Resistance-resistant antibiotics

scientific article

Resistance-resistant antibiotics is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1016/J.TIPS.2014.10.007
P3181OpenCitations bibliographic resource ID2103758
P932PMC publication ID4314344
P698PubMed publication ID25458541

P2093author name stringEric Oldfield
Xinxin Feng
P2860cites workChemotherapy for second-stage Human African trypanosomiasisQ24201785
Ancient Chinese anti-fever cure becomes panacea for malariaQ24642245
Staphylococcus aureus golden pigment impairs neutrophil killing and promotes virulence through its antioxidant activityQ24646340
A cholesterol biosynthesis inhibitor blocks Staphylococcus aureus virulenceQ24650591
Shifting from the single to the multitarget paradigm in drug discoveryQ27144242
Bisphosphonates target multiple sites in both cis- and trans-prenyltransferasesQ27645000
Lipophilic Bisphosphonates as Dual Farnesyl/Geranylgeranyl Diphosphate Synthase Inhibitors: An X-ray and NMR InvestigationQ27654261
Applying Molecular Dynamics Simulations to Identify Rarely Sampled Ligand-bound Conformational States of Undecaprenyl Pyrophosphate Synthase, an Antibacterial TargetQ27666848
Antibacterial drug leads targeting isoprenoid biosynthesisQ27675524
Dual Dehydrosqualene/Squalene Synthase Inhibitors: Leads for Innate Immune System-Based TherapeuticsQ27676950
Lipophilic analogs of zoledronate and risedronate inhibit Plasmodium geranylgeranyl diphosphate synthase (GGPPS) and exhibit potent antimalarial activityQ27677853
HIV-1 Integrase Inhibitor-Inspired Antibacterials Targeting Isoprenoid BiosynthesisQ27679484
Structure and Inhibition of Tuberculosinol Synthase and Decaprenyl Diphosphate Synthase from Mycobacterium tuberculosisQ27681516
Molecular profiling of Mycobacterium tuberculosis identifies tuberculosinyl nucleoside products of the virulence-associated enzyme Rv3378cQ27681663
Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010Q27860791
Antibacterial effect of human V gamma 2V delta 2 T cells in vivoQ28363497
Phosphoantigen/IL2 expansion and differentiation of Vγ2Vδ2 T cells increase resistance to tuberculosis in nonhuman primatesQ28535348
Trypanosoma cruzi contains major pyrophosphate stores, and its growth in vitro and in vivo is blocked by pyrophosphate analogsQ57188906
Nitrogen-containing bisphosphonates as carbocation transition state analogs for isoprenoid biosynthesisQ73062260
Antibiotics: a shot in the armQ80889978
Antibiotics at the crossroadsQ80889994
Targeting virulence: can we make evolution-proof drugs?Q87435859
Drugs for bad bugs: confronting the challenges of antibacterial discoveryQ29547723
Bioorganometallic chemistry with IspG and IspH: structure, function, and inhibition of the [Fe(4)S(4)] proteins involved in isoprenoid biosynthesis.Q31149060
Identification of a new antitubercular drug candidate, SQ109, from a combinatorial library of 1,2-ethylenediaminesQ33223601
Challenges of antibacterial discoveryQ33793074
Multitarget drug discovery for tuberculosis and other infectious diseasesQ33854785
Parasitic loads in tissues of mice infected with Trypanosoma cruzi and treated with AmBisomeQ33955428
Transferable vancomycin resistance in a community-associated MRSA lineageQ33956707
Amphotericin B: spectrum and resistanceQ34110285
The discovery of artemisinin (qinghaosu) and gifts from Chinese medicineQ34223139
The composition of Ehrlich's salvarsan: resolution of a century-old debateQ34380428
Metabolic engineering of Salmonella vaccine bacteria to boost human Vγ2Vδ2 T cell immunity.Q34560345
Progress in the discovery of treatments for C. difficile infection: A clinical and medicinal chemistry review.Q35044119
SQ109 targets MmpL3, a membrane transporter of trehalose monomycolate involved in mycolic acid donation to the cell wall core of Mycobacterium tuberculosisQ35867500
Multi-targeting by monotherapeutic antibacterials.Q36679193
Farnesyl diphosphate synthase inhibitors from in silico screeningQ36899690
Membrane lipid homeostasis in bacteriaQ37080837
From molecular fossils of bacterial hopanoids to the formation of isoprene units: discovery and elucidation of the methylerythritol phosphate pathwayQ37326534
Trypanosoma brucei aquaglyceroporin 2 is a high-affinity transporter for pentamidine and melaminophenyl arsenic drugs and the main genetic determinant of resistance to these drugsQ37579799
The emerging role of amiodarone and dronedarone in Chagas diseaseQ38032507
Multitarget ligands in antibacterial research: progress and opportunitiesQ38068475
Viable screening targets related to the bacterial cell wall.Q38070780
Ribosome-targeting antibiotics and mechanisms of bacterial resistance.Q38171225
Crystal structure of a pentamidine-oligonucleotide complex: implications for DNA-binding propertiesQ38326809
Pyrophosphate-dependent phosphofructokinase of Entamoeba histolytica: molecular cloning, recombinant expression and inhibition by pyrophosphate analoguesQ38357749
Targeting isoprenoid biosynthesis for drug discovery: bench to bedsideQ39321531
Lipophilic pyridinium bisphosphonates: potent gammadelta T cell stimulatorsQ39758159
Concurrent Chagas' disease and borderline disseminated cutaneous leishmaniasis: The role of amiodarone as an antitrypanosomatidae drugQ41360414
Statins enhance formation of phagocyte extracellular trapsQ41426439
Antibiotic effectiveness: balancing conservation against innovationQ41741779
Antibiotic resistance: An infectious arms race.Q42217180
Bisphosphonates inhibit the growth of Trypanosoma brucei, Trypanosoma cruzi, Leishmania donovani, Toxoplasma gondii, and Plasmodium falciparum: a potential route to chemotherapyQ43574122
Characterization of a novel, broad-based fungicidal activity for the antiarrhythmic drug amiodaroneQ43830145
Antifungal Activity of Amiodarone Is Mediated by Disruption of Calcium HomeostasisQ44445840
Amiodarone and itraconazole: a rational therapeutic approach for the treatment of chronic Chagas' disease.Q46006642
Orally active squalene synthase inhibitors: bis((acyloxy)alkyl) prodrugs of the alpha-phosphonosulfonic acid moietyQ46641730
Pentamidine is an uncoupler of oxidative phosphorylation in rat liver mitochondriaQ46899992
Amiodarone has intrinsic anti-Trypanosoma cruzi activity and acts synergistically with posaconazoleQ46922516
Mycobacteria possess a surprisingly small number of ribosomal RNA genes in relation to the size of their genomeQ47208727
Additivity of molecular fields: CoMFA study on dual activators of PPARalpha and PPARgammaQ48006778
An audience with...John ReedQ48375310
Resistance to polyene antibiotics and correlated sterol changes in two isolates of Candida tropicalis from a patient with an amphotericin B-resistant funguria.Q53743852
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectantibiotic resistanceQ380775
P304page(s)664-74
P577publication date2014-12-01
P1433published inTrends in Pharmacological SciencesQ2451474
P1476titleResistance-resistant antibiotics
P478volume35

Reverse relations

cites work (P2860)
Q39175852A Critical Review of Analytical Methods for Quantification of Cefotaxime.
Q91645862A Repurposing Approach for Uncovering the Anti-Tubercular Activity of FDA-Approved Drugs with Potential Multi-Targeting Profiles
Q49912940A multitarget approach to drug discovery inhibiting Mycobacterium tuberculosis PyrG and PanK.
Q37637620A stepwise introduction of a successful antimicrobial stewardship program. Experience from a tertiary care university hospital in Western, Saudi Arabia
Q35886164Antibacterial drug leads: DNA and enzyme multitargeting
Q38380313Antibacterial synergic effect of honey from two stingless bees: Scaptotrigona bipunctata Lepeletier, 1836, and S. postica Latreille, 1807.
Q36419761Antiinfectives targeting enzymes and the proton motive force.
Q26752527Antimicrobial Drugs in Fighting against Antimicrobial Resistance
Q92178633Characterization of Antimicrobial, Antioxidant, and Leishmanicidal Activities of Schiff Base Derivatives of 4-Aminoantipyrine
Q27727743Dynamic Structure and Inhibition of a Malaria Drug Target: Geranylgeranyl Diphosphate Synthase
Q28822179Endless Resistance. Endless Antibiotics?
Q53686599Failure of daptomycin to kill Staphylococcus aureus: impact of bacterial membrane fatty acid composition.
Q35963318In Vitro and in Vivo Activity of Multitarget Inhibitors against Trypanosoma brucei
Q42351008Isoprenoid Biosynthesis Inhibitors Targeting Bacterial Cell Growth.
Q92682023Ligands and Receptors with Broad Binding Capabilities Have Common Structural Characteristics: An Antibiotic Design Perspective
Q30385391Moenomycin Biosynthesis: Structure and Mechanism of Action of the Prenyltransferase MoeN5.
Q28276967Morphological and ultrastructural changes in bacterial cells as an indicator of antibacterial mechanism of action
Q52655075Novel Staphyloxanthin Inhibitors with Improved Potency against Multidrug Resistant Staphylococcus aureus.
Q26747572One for All? Hitting Multiple Alzheimer's Disease Targets with One Drug
Q59128929PLGA/Nano-ZnO Composite Particles for Use in Biomedical Applications: Preparation, Characterization, and Antimicrobial Activity
Q39039936Potential of marine natural products against drug-resistant fungal, viral, and parasitic infections.
Q38778154Research and development of antibiotics: insights from patents and citation network.
Q38755043Resisting resistance: is there a solution for malaria?
Q40072185Spontaneous mutation rate is a plastic trait associated with population density across domains of life
Q92604028Staphyloxanthin: a potential target for antivirulence therapy
Q40824085Sugar-Grafted Cyclodextrin Nanocarrier as a "Trojan Horse" for Potentiating Antibiotic Activity

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