Gene-environment interactions in genome-wide association studies: current approaches and new directions

scientific article (publication date: October 2013)

Gene-environment interactions in genome-wide association studies: current approaches and new directions is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/JCPP.12114
P3181OpenCitations bibliographic resource ID1352423
P932PMC publication ID3829379
P698PubMed publication ID23808649

P50authorStacey J WinhamQ56516227
P2093author name stringJoanna M Biernacka
P2860cites workIdentifying Important Risk Factors for Survival in Kidney Graft Failure Patients Using Random Survival ForestsQ22673963
A critical review of the first 10 years of candidate gene-by-environment interaction research in psychiatryQ24288984
Genetic sensitivity to the environment: the case of the serotonin transporter gene and its implications for studying complex diseases and traitsQ24603974
Role of genotype in the cycle of violence in maltreated childrenQ28216871
Moderating role of the MAOA genotype in antisocial behaviourQ28258683
MAOA genotype, social exclusion and aggression: an experimental test of a gene-environment interactionQ28277123
Principal interactions analysis for repeated measures data: application to gene-gene and gene-environment interactionsQ28387257
Genome-wide gene-environment interaction analysis for asbestos exposure in lung cancer susceptibilityQ28391057
Using mouse models of autism spectrum disorders to study the neurotoxicology of gene-environment interactionsQ28392778
The mystery of missing heritability: Genetic interactions create phantom heritabilityQ28732355
Does parental expressed emotion moderate genetic effects in ADHD? An exploration using a genome wide association scanQ28943283
MAOA, maltreatment, and gene–environment interaction predicting children's mental health: new evidence and a meta-analysisQ29012785
Studying gene and gene-environment effects of uncommon and common variants on continuous traits: a marker-set approach using gene-trait similarity regressionQ30428383
Review and evaluation of methods correcting for population stratification with a focus on underlying statistical principlesQ30492697
Bias in random forest variable importance measures: illustrations, sources and a solutionQ33270401
Conditional variable importance for random forestsQ33351067
Identification of gene-gene interaction using principal componentsQ33519379
Genetic association analysis of coronary heart disease by profiling gene-environment interaction based on latent components in longitudinal endophenotypes.Q33519394
Detecting gene-by-smoking interactions in a genome-wide association study of early-onset coronary heart disease using random forestsQ33519396
Prioritizing GWAS results: A review of statistical methods and recommendations for their applicationQ33571786
Early life stress, MAOA, and gene-environment interactions predict behavioral disinhibition in childrenQ33665707
Using principal components of genetic variation for robust and powerful detection of gene-gene interactions in case-control and case-only studiesQ33708556
Child maltreatment moderates the association of MAOA with symptoms of depression and antisocial personality disorderQ33732067
Methods for investigating gene-environment interactions in candidate pathway and genome-wide association studiesQ33761835
Gene set analysis of SNP data: benefits, challenges, and future directionsQ33870951
The future of association studies: gene-based analysis and replicationQ33910011
Gene--environment-wide association studies: emerging approachesQ33937986
Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancerQ33951229
i-GSEA4GWAS: a web server for identification of pathways/gene sets associated with traits by applying an improved gene set enrichment analysis to genome-wide association studyQ33957530
A versatile gene-based test for genome-wide association studiesQ33960489
Next generation analytic tools for large scale genetic epidemiology studies of complex diseasesQ34029677
Use of the gamma method for self-contained gene-set analysis of SNP dataQ34100207
mbmdr: an R package for exploring gene-gene interactions associated with binary or quantitative traitsQ34123705
Epistasis: what it means, what it doesn't mean, and statistical methods to detect it in humansQ34152058
Gene-environment interaction in psychological traits and disordersQ34158242
An R package implementation of multifactor dimensionality reductionQ34208434
A two-stage random forest-based pathway analysis methodQ34269179
A gene-based method for detecting gene-gene co-association in a case-control association studyQ34329003
SNP interaction detection with Random Forests in high-dimensional genetic dataQ34336861
A novel method to identify high order gene-gene interactions in genome-wide association studies: gene-based MDR.Q34383253
Parallel multifactor dimensionality reduction: a tool for the large-scale analysis of gene-gene interactionsQ34543070
Gene-environment interactions in human disease: nuisance or opportunity?Q34777742
Sample size requirements to detect gene-environment interactions in genome-wide association studiesQ34794234
Comparisons of multi-marker association methods to detect association between a candidate region and diseaseQ35172705
Powerful multilocus tests of genetic association in the presence of gene-gene and gene-environment interactionsQ35221734
Genetics of stress response and stress-related disordersQ35236890
Interactions between environmental factors and polymorphisms in angiogenesis pathway genes in esophageal adenocarcinoma risk: a case-only studyQ35353824
Research review: gene-environment interaction research in youth depression - a systematic review with recommendations for future researchQ35449217
A longitudinal twin study on the association between ADHD symptoms and readingQ35686641
Child abuse and neglect, MAOA, and mental health outcomes: a prospective examinationQ35808478
Inclusion of gene-gene and gene-environment interactions unlikely to dramatically improve risk prediction for complex diseasesQ36017113
Simultaneously testing for marginal genetic association and gene-environment interactionQ36402165
Association of GATA4 sequence variation with alcohol dependenceQ36418490
Natural and orthogonal interaction framework for modeling gene-environment interactions with application to lung cancerQ36501117
Powerful cocktail methods for detecting genome-wide gene-environment interactionQ36845610
Challenges and opportunities in genome-wide environmental interaction (GWEI) studiesQ36916332
Gene-environment interaction in externalizing problems among adolescents: evidence from the Pelotas 1993 Birth Cohort StudyQ37076902
Evaluation of removable statistical interaction for binary traitsQ37097369
Haplotype-association analysisQ37115923
Genome-wide association studies in ADHD.Q37175234
A partial least-square approach for modeling gene-gene and gene-environment interactions when multiple markers are genotypedQ37238577
Interaction between specific forms of childhood maltreatment and the serotonin transporter gene (5-HTT) in recurrent depressive disorderQ37302527
Invited commentary: from genome-wide association studies to gene-environment-wide interaction studies--challenges and opportunitiesQ37306204
Gene-environment interaction in genome-wide association studiesQ37321544
From nature versus nurture, via nature and nurture, to gene x environment interaction in mental disordersQ37660158
Child and adolescent psychiatric geneticsQ37688994
Molecular genetics of attention-deficit/hyperactivity disorder: an overviewQ37690166
Statistical analysis strategies for association studies involving rare variantsQ37799723
The Genetics of Child Psychiatric Disorders: Focus on Autism and Tourette SyndromeQ37801080
Rare Variant Association Analysis Methods for Complex TraitsQ37806780
Brain SCALE: brain structure and cognition: an adolescent longitudinal twin study into the genetic etiology of individual differencesQ39575529
Designing and analysing case-control studies to exploit independence of genotype and exposureQ41572695
Gene-based interaction analysis by incorporating external linkage disequilibrium informationQ41837955
A Bayesian hierarchical model for detecting haplotype-haplotype and haplotype-environment interactions in genetic association studiesQ41870175
Increasing the power of identifying gene x gene interactions in genome-wide association studiesQ41870735
Permutation and parametric bootstrap tests for gene-gene and gene-environment interactionsQ42732416
Exploiting gene-environment independence for analysis of case-control studies: an empirical Bayes-type shrinkage estimator to trade-off between bias and efficiencyQ43602602
Childhood adversity, monoamine oxidase a genotype, and risk for conduct disorderQ44903415
Testing association between disease and multiple SNPs in a candidate geneQ46112615
The combined effects of the 5-HTTLPR and 5-HTR1A genes modulates the relationship between negative life events and major depressive disorder in a Chinese populationQ46321245
Pathway analysis of single-nucleotide polymorphisms potentially associated with glioblastoma multiforme susceptibility using random forests.Q46664876
The combined effects of the BDNF and GSK3B genes modulate the relationship between negative life events and major depressive disorderQ48101596
Strong effects of environmental factors on prevalence and course of major depressive disorder are not moderated by 5-HTTLPR polymorphisms in a large Dutch sampleQ48603914
Prenatal immune activation interacts with genetic Nurr1 deficiency in the development of attentional impairments.Q48716701
LPHN3 and attention-deficit/hyperactivity disorder: interaction with maternal stress during pregnancy.Q50762347
Interaction between MAO-A genotype and maltreatment in the risk for conduct disorder: failure to confirm in adolescent patients.Q51916605
Estimation of magnitude in gene-environment interactions in the presence of measurement error.Q52001293
Truncated product method for combining P-values.Q52936699
Identifying SNPs predictive of phenotype using random forestsQ57363161
Genetic influence on smoking--a study of male twinsQ68022601
The effect of misclassification in the presence of covariatesQ71347668
Limitations of the case-only design for identifying gene-environment interactionsQ74599234
Exploiting gene-environment interaction to detect genetic associationsQ79731627
MAOA and the "cycle of violence:" childhood abuse and neglect, MAOA genotype, and risk for violent and antisocial behaviorQ79824292
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectgenome-wide association studyQ1098876
P304page(s)1120-34
P577publication date2013-10-01
P1433published inThe Journal of Child Psychology and PsychiatryQ6294936
P1476titleGene-environment interactions in genome-wide association studies: current approaches and new directions
P478volume54

Reverse relations

cites work (P2860)
Q36411231A genetic stochastic process model for genome-wide joint analysis of biomarker dynamics and disease susceptibility with longitudinal data.
Q92815913A genetic sum score of risk alleles associated with body mass index interacts with socioeconomic position in the Heinz Nixdorf Recall Study
Q35145722Assessing gene-environment interactions for common and rare variants with binary traits using gene-trait similarity regression
Q36209594Associations of prodynorphin sequence variation with alcohol dependence and related traits are phenotype-specific and sex-dependent.
Q47876061Author's reply: Considerations of context, distractions by politics and evaluations of evidence
Q37166191Beyond main effects of gene-sets: harsh parenting moderates the association between a dopamine gene-set and child externalizing behavior
Q34940625Correcting systematic inflation in genetic association tests that consider interaction effects: application to a genome-wide association study of posttraumatic stress disorder.
Q37621129Dose-dependent cannabis use, depressive symptoms, and FAAH genotype predict sleep quality in emerging adults: a pilot study
Q36782711GENOME-WIDE ASSOCIATION STUDY (GWAS) AND GENOME-WIDE BY ENVIRONMENT INTERACTION STUDY (GWEIS) OF DEPRESSIVE SYMPTOMS IN AFRICAN AMERICAN AND HISPANIC/LATINA WOMEN.
Q89625837Gene expression in peripheral blood in treatment-free major depression
Q47681304Gene-based interaction analysis shows GABAergic genes interacting with parenting in adolescent depressive symptoms.
Q27027836Genetic determinants of depression: recent findings and future directions
Q35738812Genetics of cardiovascular disease: Importance of sex and ethnicity
Q39469472Genome-wide gene-environment interaction analysis of pesticide exposure and risk of Parkinson's disease
Q31049597Genomic Bayesian Prediction Model for Count Data with Genotype × Environment Interaction
Q94544800Identifying novel associations in GWAS by hierarchical Bayesian latent variable detection of differentially misclassified phenotypes
Q60045127Improving pharmacogenetic prediction of extrapyramidal symptoms induced by antipsychotics
Q30000261Integrating Genetic, Neuropsychological and Neuroimaging Data to Model Early-Onset Obsessive Compulsive Disorder Severity
Q92754531Isfahan Twins Registry (ITR): An Invaluable Platform for Epidemiological and Epigenetic Studies: Design and Methodology of ITR
Q47336884Keeping Pace with the Red Queen: Identifying the Genetic Basis of Susceptibility to Infectious Disease.
Q98499811Long-term antibiotic use during early life and risks to mental traits: an observational study and gene-environment-wide interaction study in UK Biobank cohort
Q41577410The Roles of Genes in the Neuronal Migration and Neurite Outgrowth Network in Developmental Dyslexia: Single- and Multiple-Risk Genetic Variants
Q91665877The UKB envirome of depression: from interactions to synergistic effects

Search more.