Advances in the research of melatonin in autism spectrum disorders: literature review and new perspectives

scientific article (publication date: 14 October 2013)

Advances in the research of melatonin in autism spectrum disorders: literature review and new perspectives is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.3390/IJMS141020508
P932PMC publication ID3821628
P698PubMed publication ID24129182
P5875ResearchGate publication ID257838638

P50authorSylvie TordjmanQ98512945
P2093author name stringDavid Cohen
Eric Bellissant
Guillaume Bronsard
Michel Botbol
George M Anderson
Solenn Kermarrec
Imen Najjar
Olivier Schischmanoff
Nemat Jaafari
Claire Fougerou
Julie Vernay-Leconte
Marianne Barburoth
Enas Lagdas
Rémi Fagard
Sophie Ribardiere
P2860cites workMutation screening of melatonin-related genes in patients with autism spectrum disordersQ21202036
Crystal structure and functional mapping of human ASMT, the last enzyme of the melatonin synthesis pathwayQ24292879
Perinatal and neonatal risk factors for autism: a comprehensive meta-analysisQ24594076
International Union of Basic and Clinical Pharmacology. LXXV. Nomenclature, classification, and pharmacology of G protein-coupled melatonin receptorsQ24623433
Newborn infants detect the beat in musicQ24645247
Abnormal melatonin synthesis in autism spectrum disordersQ24652560
Foundations for a new science of learningQ24657078
Neural stem cells express melatonin receptors and neurotrophic factors: colocalization of the MT1 receptor with neuronal and glial markersQ24795063
Is ASMT a susceptibility gene for autism spectrum disorders? A replication study in European populationsQ28254534
A circadian clock entrained by melatonin is ticking in the rat fetal adrenalQ28568085
Melatonin affects the temporal organization of the song of the zebra finchQ45299460
Epilepsy in autism is associated with intellectual disability and gender: evidence from a meta-analysisQ45375790
Light-at-night-induced circadian disruption, cancer and agingQ45817978
Oxidative stress after sulfur mustard intoxication and its reduction by melatonin: efficacy of antioxidant therapy during serious intoxication.Q45907352
The tick-tock of language: is language processing sensitive to circadian rhythmicity and elevated sleep pressure?Q45918046
Endogenous melatonin provides an effective circadian message to both the suprachiasmatic nuclei and the pars tuberalis of the rat.Q46193443
Melatonin and the circadian entrainment of metabolic and hormonal activities in primary isolated adipocytes.Q46459035
Melatonin is able to prevent the liver of old castrated female rats from oxidative and pro-inflammatory damageQ46523902
Melatonin as a local regulator of human placental functionQ46692866
A randomized, placebo-controlled trial of controlled release melatonin treatment of delayed sleep phase syndrome and impaired sleep maintenance in children with neurodevelopmental disabilitiesQ46851680
Light-induced melatonin suppression in humans with polychromatic and monochromatic lightQ46853731
Behavioral manifestations of autism in the first year of lifeQ47620861
Melatonin: helping to MEND impaired sleepQ48193622
Sleep-wake characterization of double MT₁/MT₂ receptor knockout mice and comparison with MT₁ and MT₂ receptor knockout miceQ48199618
Exploring motor system contributions to the perception of social information: Evidence from EEG activity in the mu/alpha frequency rangeQ48228121
CYP1A2 polymorphisms in slow melatonin metabolisers: a possible relationship with autism spectrum disorder?Q48232008
Controlled-release melatonin, singly and combined with cognitive behavioural therapy, for persistent insomnia in children with autism spectrum disorders: a randomized placebo-controlled trialQ48243417
Serum melatonin kinetics and long-term melatonin treatment for sleep disorders in Rett syndromeQ48260113
Effects of melatonin should be studied separately in each neurodevelopmental disorder and with specific sleep diagnosesQ48268054
Meta-analysing the effectiveness of melatonin for sleep-disturbed individuals with autism spectrum conditions: should Rett syndrome be included?Q48288602
Prolonged-release melatonin for children with neurodevelopmental disordersQ48294909
Oxytocin administration to parent enhances infant physiological and behavioral readiness for social engagementQ48440643
Randomized controlled trial of melatonin for children with autistic spectrum disorders and sleep problems.Q48492643
Melatonin profiles and sleep characteristics in boys with fragile X syndrome: a preliminary studyQ48704147
Effect of melatonin on sleep-wake rhythm: the sleep diary of an autistic maleQ48704186
Parental report of sleep problems in children with autismQ48721115
Genetics of childhood disorders: XLV. Autism, part 4: serotonin in autismQ44226251
Effectiveness of melatonin in the treatment of sleep disturbances in children with Asperger disorderQ44476522
Prophylactic treatment with melatonin after status epilepticus: effects on epileptogenesis, neuronal damage, and behavioral changes in a kainate model of temporal lobe epilepsyQ44517611
Sleep problems in children with mental handicapQ45054456
'A child with severe night terrors and sleep-walking responds to melatonin therapy'.Q45148578
Nocturnal excretion of 6-sulphatoxymelatonin in children and adolescents with autistic disorder.Q45225955
Experimental evidence for synchronization to a musical beat in a nonhuman animalQ29618656
Social interaction shapes babbling: testing parallels between birdsong and speechQ30011090
Measuring progress in children with autism spectrum disorder who have cochlear implants.Q30341551
Do parentese prosody and fathers' involvement in interacting facilitate social interaction in infants who later develop autism?Q30454840
Do parents recognize autistic deviant behavior long before diagnosis? Taking into account interaction using computational methodsQ30474587
Multiplex ligation-dependent probe amplification for genetic screening in autism spectrum disorders: efficient identification of known microduplications and identification of a novel microduplication in ASMT.Q30484771
Tissue-specific abolition of Per1 expression in the pars tuberalis by pinealectomy in the Syrian hamster.Q32106539
Disorganized rhythm and synchrony: early signs of autism and Rett syndromeQ33223913
Early language acquisition: cracking the speech codeQ33268733
Identification of pathway-biased and deleterious melatonin receptor mutants in autism spectrum disorders and in the general populationQ33640009
Melatonin treatment of non-epileptic myoclonus in childrenQ33651060
Inter-brain synchronization during social interactionQ33680796
Melatonin treatment of sleep-wake cycle disorders in children and adolescentsQ33716209
Melatonin in children with autistic spectrum disorders: recent and practical dataQ33832237
Sleep patterns of children with pervasive developmental disordersQ33947349
Naturally occurring variations in maternal behavior in the rat are associated with differences in estrogen-inducible central oxytocin receptorsQ33948059
Melatonin for insomnia in children with autism spectrum disordersQ34009306
Melatonin versus placebo in children with autism spectrum conditions and severe sleep problems not amenable to behaviour management strategies: a randomised controlled crossover trial.Q34022705
Infant intersubjectivity: research, theory, and clinical applicationsQ34155460
Melatonin in autism spectrum disorders: a systematic review and meta-analysis.Q34180346
Isolation of melatonin and 5-methoxyindole-3-acetic acid from bovine pineal glandsQ34262263
The nuclear receptor REV-ERBα is required for the daily balance of carbohydrate and lipid metabolismQ34273148
Human aging and melatonin. Clinical relevance.Q34280211
Treatment outcomes in REM sleep behavior disorder.Q34324499
Melatonin protects against apoptosis-inducing factor (AIF)-dependent cell death during acetaminophen-induced acute liver failureQ34525832
An open-label study of controlled-release melatonin in treatment of sleep disorders in children with autism.Q34555558
Arylalkylamine N-acetyltransferase: "the Timezyme".Q34573239
Social timing, clock genes and autism: a new hypothesisQ34631344
Melatonin for sleep in children with autism: a controlled trial examining dose, tolerability, and outcomesQ34634252
Organisation of the circadian system in melatonin-proficient C3H and melatonin-deficient C57BL mice: a comparative investigationQ34732778
The chronobiotic properties of melatoninQ34732782
Exogenous melatonin for sleep problems in individuals with intellectual disability: a meta-analysisQ34976753
Melatonin in treatment of chronic sleep disorders in adults with autism: a retrospective studyQ34981745
Melatonin: a clock-output, a clock-inputQ35080104
Sleep disorder in Rett syndrome and melatonin treatmentQ48736466
Sleep problems in autism: prevalence, cause, and interventionQ48770519
An investigation into sleep characteristics of children with autism and Asperger's Disorder.Q48772674
What is melatonin? Is it a useful treatment for sleep problems in autism?Q48789268
Sleep dysfunction in Rett syndrome: a trial of exogenous melatonin treatmentQ48801982
The sleep/wake rhythm in children with autismQ48810591
The treatment of sleep disorders with melatonin.Q48852405
An investigation on sleep disturbance of autistic children.Q49091055
Evidence of pineal endocrine hypofunction in autistic childrenQ49253980
Are there "autistic-like" features in congenitally blind children?Q50302275
More on melatoninQ50302331
Brief report: circadian melatonin, thyroid-stimulating hormone, prolactin, and cortisol levels in serum of young adults with autismQ50303476
Autism and hypomelanosis of Ito in twinsQ50304854
Day and nighttime excretion of 6-sulphatoxymelatonin in adolescents and young adults with autistic disorderQ50307004
Brief report: Recognition of autism spectrum disorder before one year of age: a retrospective study based on home videotapesQ50312874
Usefulness of melatonin for developmental sleep and emotional/behavior disorders--studies of melatonin trial on 50 patients with developmental disordersQ50313606
Pharmacokinetics of melatonin in human sexual maturation.Q51033617
Melatonin reduces X-ray radiation-induced lung injury in mice by modulating oxidative stress and cytokine expression.Q53358016
Very early signs of autism reported by parents include many concerns not specific to autism criteriaQ58171415
Adipokines and Adipocyte Function in Clock Mutant Mice That Retain Melatonin RhythmicityQ59709675
Twenty-four hour urinary excretion of 6-hydroxymelatonin sulfate in Down syndrome subjectsQ71121577
The cross-modal coordination of interpersonal timing: six-week-olds infants' gaze with adults' vocal behaviorQ77850623
Behavioral speed contagion: automatic modulation of movement timing by observation of body movementsQ80571183
Circadian modulation of human erythrocyte plasma membrane redox system by melatoninQ84073737
Elevated daytime melatonin concentrations in autism: A pilot studyQ88998440
Melatonin action in the pituitary: neuroendocrine synchronizer and developmental modulator?Q35080117
Generation of the melatonin endocrine message in mammals: a review of the complex regulation of melatonin synthesis by norepinephrine, peptides, and other pineal transmittersQ35139570
Systematic review of melatonin treatment in children with neurodevelopmental disabilities and sleep impairmentQ35947025
Melatonin therapy for circadian rhythm sleep disorders in children with multiple disabilities: what have we learned in the last decade?Q35947030
Oscillation of clock and clock controlled genes induced by serum shock in human breast epithelial and breast cancer cells: regulation by melatoninQ36251714
Melatonin for sleep problems in children with neurodevelopmental disorders: randomised double masked placebo controlled trialQ36372805
Melatonin and human rhythmsQ36474457
Therapeutic application of melatonin in mild cognitive impairment.Q36576496
Altered circadian expression of cytokines and cytolytic factors in splenic natural killer cells of Per1(-/-) mutant miceQ36679671
Parent-infant synchrony and the construction of shared timing; physiological precursors, developmental outcomes, and risk conditionsQ36758633
The efficacy of melatonin for sleep problems in children with autism, fragile X syndrome, or autism and fragile X syndrome.Q37161368
The roles of melatonin and light in the pathophysiology and treatment of circadian rhythm sleep disordersQ37217240
Gene expression profiling differentiates autism case-controls and phenotypic variants of autism spectrum disorders: evidence for circadian rhythm dysfunction in severe autism.Q37332233
Long-term effects of melatonin on quality of life and sleep in haemodialysis patients (Melody study): a randomized controlled trialQ37369290
Circadian rhythms and sleep in children with autismQ37644989
Getting answers from babies about autismQ37675414
Clinical uses of melatonin: evaluation of human trialsQ37737750
At the crossroads between psychoanalysis and neuroscience: The importance of subjectivityQ37785271
Melatonin as the most effective organizer of the rhythm of protein synthesis in hepatocytes in vitro and in vivoQ37808501
Melatonin for disordered sleep in individuals with autism spectrum disorders: systematic review and discussion.Q37851731
Melatonin as a central molecule connecting neural development and calcium signalingQ37861604
Infant rhythms versus parental time: promoting parent-infant synchronyQ37904031
Melatonin: both master clock output and internal time-giver in the circadian clocks networkQ37931490
Sleep in children with autism spectrum disorderQ38042257
Melatonin and clock genes expression in the cardiovascular systemQ38070615
Effect of chronic melatonin administration on several physiological parameters from old Wistar rats and SAMP8 mice.Q38079647
Plasma beta-endorphin, adrenocorticotropin hormone, and cortisol in autismQ39115297
The pineal gland: a neurochemical transducerQ39874149
Concepts of autism: a review of researchQ39980651
Melatonin. A Mammalian Pineal Hormone*Q40126035
Use of melatonin in the treatment of paediatric sleep disordersQ41301692
Melatonin site and mechanism of action: single or multiple?Q41649636
Melatonin: a sleep-promoting hormone.Q41672320
Rhythmic gene expression in pituitary depends on heterologous sensitization by the neurohormone melatoninQ42166598
Long-term oral administration of melatonin improves spatial learning and memory and protects against cholinergic degeneration in middle-aged Ts65Dn mice, a model of Down syndromeQ42519840
Melatonin: a panacea for desperate parents? (Hype or truth).Q42699214
Loss of response to melatonin treatment is associated with slow melatonin metabolism.Q43006480
Brain serotonin and dopamine transporter bindings in adults with high-functioning autism.Q43202668
Urinary excretion of 5-hydroxyindoleacetic acid, serotonin and 6-sulphatoxymelatonin in normoserotonemic and hyperserotonemic autistic individualsQ43239157
Daily infusion of melatonin entrains circadian activity rhythms in the diurnal rodent Arvicanthis ansorgeiQ44016871
Entrainment of circadian activity rhythms in rats to melatonin administered at T cycles different from 24 hoursQ44037246
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectautism spectrum disorderQ1436063
melatoninQ180912
heterocyclic compoundQ193430
catalysisQ82264
organic chemistryQ11351
pervasive developmental disorderQ6691991
hormoneQ11364
autismQ38404
P5008on focus list of Wikimedia projectScienceSourceQ55439927
P304page(s)20508-42
P577publication date2013-10-14
P1433published inInternational Journal of Molecular SciencesQ3153277
P1476titleAdvances in the research of melatonin in autism spectrum disorders: literature review and new perspectives
P478volume14

Reverse relations

cites work (P2860)
Q30577543A novel automated behavioral test battery assessing cognitive rigidity in two genetic mouse models of autism
Q99548991Analyzing the Potential Biological Determinants of Autism Spectrum Disorder: From Neuroinflammation to the Kynurenine Pathway
Q28080719Autism as a disorder of biological and behavioral rhythms: toward new therapeutic perspectives
Q38246388Autism biomarkers: challenges, pitfalls and possibilities
Q59326917Brain hyperserotonemia causes autism-relevant social deficits in mice
Q38939664Clock Genes and Altered Sleep-Wake Rhythms: Their Role in the Development of Psychiatric Disorders.
Q28082433Complementary and Alternative Therapies for Autism Spectrum Disorder
Q38271292Current Phase II investigational therapies for insomnia
Q33997473Gene × Environment interactions in autism spectrum disorders: role of epigenetic mechanisms.
Q47653834Immune-pineal axis - acute inflammatory responses coordinate melatonin synthesis by pinealocytes and phagocytes.
Q92711524Investigating Potential Biomarkers in Autism Spectrum Disorder
Q50418448Low maternal melatonin level increases autism spectrum disorder risk in children
Q50304298Making progress in autism drug discovery
Q47739841Melatonin and circadian rhythms in autism: Case report
Q39061446Melatonin: pharmacology, functions and therapeutic benefits
Q59791335Molecular Pathology and Pharmacological Treatment of Autism Spectrum Disorder-Like Phenotypes Using Rodent Models
Q61798771Morning Plasma Melatonin Differences in Autism: Beyond the Impact of Pineal Gland Volume
Q47557441New perspectives on the role of melatonin in human sleep, circadian rhythms and their regulation
Q47936966Nocturnal light pollution and underexposure to daytime sunlight: Complementary mechanisms of circadian disruption and related diseases
Q30235312Role of Genetics in the Etiology of Autistic Spectrum Disorder: Towards a Hierarchical Diagnostic Strategy
Q38684197Sleep in Children with Autism Spectrum Disorder.
Q88935101Sleep in Infants and Children with Prenatal Alcohol Exposure
Q65000720Systematic Review of Sleep Disturbances and Circadian Sleep Desynchronization in Autism Spectrum Disorder: Toward an Integrative Model of a Self-Reinforcing Loop.
Q90396141The Neurochemistry of Autism
Q102075254The influence of circadian rhythms and aerobic glycolysis in autism spectrum disorder
Q30436298The melatonin receptor agonist ramelteon effectively treats insomnia and behavioral symptoms in autistic disorder
Q34739720The relationship between sleep and behavior in autism spectrum disorder (ASD): a review
Q64235901Updated View on the Relation of the Pineal Gland to Autism Spectrum Disorders

Search more.