Diesel exhaust particles induce the over expression of tumor necrosis factor-alpha (TNF-alpha) gene in alveolar macrophages and failed to induce apoptosis through activation of nuclear factor-kappaB (NF-kappaB)

scientific article (publication date: April 2005)

Diesel exhaust particles induce the over expression of tumor necrosis factor-alpha (TNF-alpha) gene in alveolar macrophages and failed to induce apoptosis through activation of nuclear factor-kappaB (NF-kappaB) is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3390/IJERPH2005010107
P932PMC publication ID3814704
P698PubMed publication ID16705808

P2093author name stringMichael C Madden
Ramzi M Kafoury
P2860cites workMultiple nuclear factors interact with the immunoglobulin enhancer sequencesQ24296245
Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1Q24564855
Cooperativity between oxidants and tumor necrosis factor in the activation of nuclear factor (NF)-kappaB: requirement of Ras/mitogen-activated protein kinases in the activation of NF-kappaB by oxidantsQ26341684
Phosphorylation meets ubiquitination: the control of NF-[kappa]B activityQ27860643
MAP3K-related kinase involved in NF-kappaB induction by TNF, CD95 and IL-1Q28302936
Distinct mechanisms for regulation of the interleukin-8 gene involve synergism and cooperativity between C/EBP and NF-kappa BQ28646362
Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseasesQ29547555
TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaBQ29614706
An essential role for NF-kappaB in preventing TNF-alpha-induced cell deathQ29614707
Suppression of TNF-alpha-induced apoptosis by NF-kappaBQ29618717
Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell deathQ29620021
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Series introduction: the transcription factor NF-kappaB and human diseaseQ34116362
Urban particle-induced apoptosis and phenotype shifts in human alveolar macrophagesQ34937358
Suppression of alveolar macrophage membrane receptor-mediated phagocytosis by model and actual particle-adsorbate complexes. Initial contact with the alveolar macrophage membraneQ35033340
Oxidative Stress and Gene Transcription in Asthma and Chronic Obstructive Pulmonary Disease: Antioxidant Therapeutic TargetsQ35560623
Phagocytosis by cells of the pulmonary alveoli. Transformation of crystalline particlesQ36058778
Tumor necrosis factor. Characterization at the molecular, cellular and in vivo levelQ36404676
Global increases in allergic respiratory disease: the possible role of diesel exhaust particlesQ36828722
Lipopolysaccharide inhibits TNF-induced apoptosis: role of nuclear factor-kappaB activation and reactive oxygen intermediatesQ38328387
Nuclear factor-kappaB regulates inflammatory cell apoptosis and phagocytosis in rat carrageenin-sponge implant modelQ38339730
Soluble and insoluble air particle fractions induce differential production of tumor necrosis factor alpha in rat lungQ39687809
Protective role of nuclear factor kappa B against nitric oxide-induced apoptosis in J774 macrophagesQ40811159
The role of a mitochondrial pathway in the induction of apoptosis by chemicals extracted from diesel exhaust particlesQ40860919
Chemicals in diesel exhaust particles generate reactive oxygen radicals and induce apoptosis in macrophages.Q40918316
Bcl-2 down-regulates the activity of transcription factor NF-kappaB induced upon apoptosisQ41189266
Resolution of chronic inflammation by therapeutic induction of apoptosisQ41334764
The role of diesel exhaust particles and their associated polyaromatic hydrocarbons in the induction of allergic airway diseaseQ41518439
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Macrophages are necessary for maximal nuclear factor-kappa B activation in response to endotoxinQ43968762
Ambient PM(10) extracts inhibit phagocytosis of defined inert model particles by alveolar macrophagesQ44005049
Involvement of reactive oxygen species in the metabolic pathways triggered by diesel exhaust particles in human airway epithelial cellsQ44429139
Benzo(a)pyrene-coated onto Fe2O3 particles-induced apoptotic events in the lungs of Sprague–Dawley ratsQ44442820
Enhancement of allergic inflammation by the interaction between diesel exhaust particles and the immune systemQ46981373
Inhibition of TNF-induced apoptosis by NF-kappa B.Q47721535
Diesel exhaust particles stimulate human airway epithelial cells to produce cytokines relevant to airway inflammation in vitroQ47904688
Diesel exhaust particles enhance lung injury related to bacterial endotoxin through expression of proinflammatory cytokines, chemokines, and intercellular adhesion molecule-1.Q51718393
Detection of alveolar macrophage-derived IL-1 beta in asthma. Inhibition with corticosteroidsQ67907838
TNF alpha and increased chemokine expression in rat lung after particle exposureQ70991101
Redox regulation of activation of NF-kappa B transcription factor complex: effects of N-acetylcysteineQ71521694
Biological effects of diesel exhaust particles (DEP). III. Pathogenesis of asthma like symptoms in miceQ71561840
Generation of reactive oxygen species during interaction of diesel exhaust particle components with NADPH-cytochrome P450 reductase and involvement of the bioactivation in the DNA damageQ71939421
The pro- or anti-apoptotic function of NF-kappaB is determined by the nature of the apoptotic stimulusQ73883742
IkappaB-NF-kappaB structures: at the interface of inflammation controlQ77726306
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectTNFQ18032037
NF-κBQ411114
macrophageQ184204
P304page(s)107-13
P577publication date2005-04-01
P1433published inInternational Journal of Environmental Research and Public HealthQ6051382
P1476titleDiesel exhaust particles induce the over expression of tumor necrosis factor-alpha (TNF-alpha) gene in alveolar macrophages and failed to induce apoptosis through activation of nuclear factor-kappaB (NF-kappaB)
P478volume2

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cites work (P2860)
Q58564818Acute Exposure to Diesel-Biodiesel Particulate Matter Promotes Murine Lung Oxidative Stress by Nrf2/HO-1 and Inflammation Through the NF-kB/TNF-α Pathways
Q33565699Chronic traffic-induced PM exposure and self-reported respiratory and cardiovascular health in the RHINE Tartu Cohort
Q42546881Curcumin pretreatment protects against PM2.5‑induced oxidized low‑density lipoprotein‑mediated oxidative stress and inflammation in human microvascular endothelial cells
Q92258666Deciphering the Code between Air Pollution and Disease: The Effect of Particulate Matter on Cancer Hallmarks
Q28391796Diesel exhaust particles modulate the tight junction protein occludin in lung cells in vitro
Q50074745From the Cover: Lung-Specific Overexpression of Constitutively Active IKK2 Induces Pulmonary and Systemic Inflammations but Not Hypothalamic Inflammation and Glucose Intolerance
Q92073581Glucose Homeostasis following Diesel Exhaust Particulate Matter Exposure in a Lung Epithelial Cell-Specific IKK2-Deficient Mouse Model
Q35125366Pro-inflammatory mediation of myoblast proliferation
Q37649363Proximity to a Major Road and Plasma Cytokines in School-Aged Children.
Q41046950Role of tumor necrosis factor-α and its receptors in diesel exhaust particle-induced pulmonary inflammation
Q88477988Transgenic up-regulation of Claudin-6 decreases fine diesel particulate matter (DPM)-induced pulmonary inflammation

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