Complementation analysis in PtdInsP kinase-deficient yeast mutants demonstrates that Schizosaccharomyces pombe and murine Fab1p homologues are phosphatidylinositol 3-phosphate 5-kinases

scientific journal article

Complementation analysis in PtdInsP kinase-deficient yeast mutants demonstrates that Schizosaccharomyces pombe and murine Fab1p homologues are phosphatidylinositol 3-phosphate 5-kinases is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.274.48.33905
P698PubMed publication ID10567352
P5875ResearchGate publication ID12734575

P50authorPeter Joseph Jacques ParkerQ21165177
Robert Hall MichellQ21165643
P2093author name stringA B Holmes
Y Ohya
A Shisheva
G F Painter
F T Cooke
R K McEwen
S K Dove
P2860cites workActive and inactive protein kinases: structural basis for regulationQ29616320
Vectors for the inducible overexpression of glutathione S-transferase fusion proteins in yeastQ29618547
Phosphoinositide 3-kinases and their FYVE domain-containing effectors as regulators of vacuolar/lysosomal membrane trafficking pathwaysQ33545062
The sequence of phosphatidylinositol-4-phosphate 5-kinase defines a novel family of lipid kinasesQ34318366
Phosphatidylinositol 3,5-bisphosphate defines a novel PI 3-kinase pathway in resting mouse fibroblastsQ34427650
Osmotic stress activates phosphatidylinositol-3,5-bisphosphate synthesisQ34446025
Distinct roles for the p110alpha and hVPS34 phosphatidylinositol 3'-kinases in vesicular trafficking, regulation of the actin cytoskeleton, and mitogenesisQ36255998
Role for phosphatidylinositol 3-kinase in the sorting and transport of newly synthesized lysosomal enzymes in mammalian cellsQ36382633
Nucleosomal location of the STE6 TATA box and Mat alpha 2p-mediated repressionQ36654886
Identification of an early endosomal protein regulated by phosphatidylinositol 3-kinase.Q36655286
Characterization of VPS34, a gene required for vacuolar protein sorting and vacuole segregation in Saccharomyces cerevisiaeQ36775602
Domain movements in protein kinasesQ40504109
Phosphoinositides as regulators in membrane trafficQ40968891
Lipid kinase and protein kinase activities of G-protein-coupled phosphoinositide 3-kinase gamma: structure-activity analysis and interactions with wortmannin.Q41108091
Metabolic and structural evidence for the existence of a third species of polyphosphoinositide in cells: D-phosphatidyl-myo-inositol 3-phosphateQ42067723
cAMP-dependent protein kinase: crystallographic insights into substrate recognition and phosphotransferQ42844060
A family of yeast expression vectors containing the phage f1 intergenic regionQ45019834
A functional PtdIns(3)P-binding motifQ47713511
PIPkins1, their substrates and their products: new functions for old enzymesQ48566438
Structure of Type IIβ Phosphatidylinositol Phosphate KinaseQ56603096
Type I phosphatidylinositol-4-phosphate 5-kinases are distinct members of this novel lipid kinase familyQ24336406
Cloning, characterization, and expression of a novel Zn2+-binding FYVE finger-containing phosphoinositide kinase in insulin-sensitive cellsQ24554631
Novel PI(4)P 5-kinase homologue, Fab1p, essential for normal vacuole function and morphology in yeastQ24619173
Vac7p, a novel vacuolar protein, is required for normal vacuole inheritance and morphologyQ24644105
Fab1p is essential for PtdIns(3)P 5-kinase activity and the maintenance of vacuolar size and membrane homeostasisQ27931112
Phosphatidylinositol(3)-phosphate signaling mediated by specific binding to RING FYVE domainsQ27933286
Phosphatidylinositol-4-phosphate 5-kinase localized on the plasma membrane is essential for yeast cell morphogenesisQ27935369
Protein sorting in Saccharomyces cerevisiae: isolation of mutants defective in the delivery and processing of multiple vacuolar hydrolasesQ27937990
MSS4, a phosphatidylinositol-4-phosphate 5-kinase required for organization of the actin cytoskeleton in Saccharomyces cerevisiae.Q27939032
The stress-activated phosphatidylinositol 3-phosphate 5-kinase Fab1p is essential for vacuole function in S. cerevisiaeQ27939343
Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sortingQ27940116
PIKfyve, a mammalian ortholog of yeast Fab1p lipid kinase, synthesizes 5-phosphoinositides. Effect of insulinQ28140455
PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cellsQ28236975
A new pathway for synthesis of phosphatidylinositol-4,5-bisphosphateQ28254402
Type I phosphatidylinositol-4-phosphate 5-kinases. Cloning of the third isoform and deletion/substitution analysis of members of this novel lipid kinase familyQ28267069
FYVE fingers bind PtdIns(3)PQ28279043
Endosomal localization of the autoantigen EEA1 is mediated by a zinc-binding FYVE fingerQ28289331
Pathway of phosphatidylinositol(3,4,5)-trisphosphate synthesis in activated neutrophilsQ28327099
Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reactionQ28378871
Phosphatidylinositol-4-phosphate 5-kinase isozymes catalyze the synthesis of 3-phosphate-containing phosphatidylinositol signaling moleculesQ28640210
Type I phosphatidylinositol-4-phosphate 5-kinases synthesize the novel lipids phosphatidylinositol 3,5-bisphosphate and phosphatidylinositol 5-phosphateQ28678918
P433issue48
P407language of work or nameEnglishQ1860
P921main subjectSchizosaccharomyces pombeQ2236682
P1104number of pages8
P304page(s)33905-33912
P577publication date1999-11-01
P1433published inJournal of Biological ChemistryQ867727
P1476titleComplementation analysis in PtdInsP kinase-deficient yeast mutants demonstrates that Schizosaccharomyces pombe and murine Fab1p homologues are phosphatidylinositol 3-phosphate 5-kinases
P478volume274

Reverse relations

cites work (P2860)
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