scholarly article | Q13442814 |
P50 | author | Peter Joseph Jacques Parker | Q21165177 |
Robert Hall Michell | Q21165643 | ||
P2093 | author name string | A B Holmes | |
Y Ohya | |||
A Shisheva | |||
G F Painter | |||
F T Cooke | |||
R K McEwen | |||
S K Dove | |||
P2860 | cites work | Active and inactive protein kinases: structural basis for regulation | Q29616320 |
Vectors for the inducible overexpression of glutathione S-transferase fusion proteins in yeast | Q29618547 | ||
Phosphoinositide 3-kinases and their FYVE domain-containing effectors as regulators of vacuolar/lysosomal membrane trafficking pathways | Q33545062 | ||
The sequence of phosphatidylinositol-4-phosphate 5-kinase defines a novel family of lipid kinases | Q34318366 | ||
Phosphatidylinositol 3,5-bisphosphate defines a novel PI 3-kinase pathway in resting mouse fibroblasts | Q34427650 | ||
Osmotic stress activates phosphatidylinositol-3,5-bisphosphate synthesis | Q34446025 | ||
Distinct roles for the p110alpha and hVPS34 phosphatidylinositol 3'-kinases in vesicular trafficking, regulation of the actin cytoskeleton, and mitogenesis | Q36255998 | ||
Role for phosphatidylinositol 3-kinase in the sorting and transport of newly synthesized lysosomal enzymes in mammalian cells | Q36382633 | ||
Nucleosomal location of the STE6 TATA box and Mat alpha 2p-mediated repression | Q36654886 | ||
Identification of an early endosomal protein regulated by phosphatidylinositol 3-kinase. | Q36655286 | ||
Characterization of VPS34, a gene required for vacuolar protein sorting and vacuole segregation in Saccharomyces cerevisiae | Q36775602 | ||
Domain movements in protein kinases | Q40504109 | ||
Phosphoinositides as regulators in membrane traffic | Q40968891 | ||
Lipid kinase and protein kinase activities of G-protein-coupled phosphoinositide 3-kinase gamma: structure-activity analysis and interactions with wortmannin. | Q41108091 | ||
Metabolic and structural evidence for the existence of a third species of polyphosphoinositide in cells: D-phosphatidyl-myo-inositol 3-phosphate | Q42067723 | ||
cAMP-dependent protein kinase: crystallographic insights into substrate recognition and phosphotransfer | Q42844060 | ||
A family of yeast expression vectors containing the phage f1 intergenic region | Q45019834 | ||
A functional PtdIns(3)P-binding motif | Q47713511 | ||
PIPkins1, their substrates and their products: new functions for old enzymes | Q48566438 | ||
Structure of Type IIβ Phosphatidylinositol Phosphate Kinase | Q56603096 | ||
Type I phosphatidylinositol-4-phosphate 5-kinases are distinct members of this novel lipid kinase family | Q24336406 | ||
Cloning, characterization, and expression of a novel Zn2+-binding FYVE finger-containing phosphoinositide kinase in insulin-sensitive cells | Q24554631 | ||
Novel PI(4)P 5-kinase homologue, Fab1p, essential for normal vacuole function and morphology in yeast | Q24619173 | ||
Vac7p, a novel vacuolar protein, is required for normal vacuole inheritance and morphology | Q24644105 | ||
Fab1p is essential for PtdIns(3)P 5-kinase activity and the maintenance of vacuolar size and membrane homeostasis | Q27931112 | ||
Phosphatidylinositol(3)-phosphate signaling mediated by specific binding to RING FYVE domains | Q27933286 | ||
Phosphatidylinositol-4-phosphate 5-kinase localized on the plasma membrane is essential for yeast cell morphogenesis | Q27935369 | ||
Protein sorting in Saccharomyces cerevisiae: isolation of mutants defective in the delivery and processing of multiple vacuolar hydrolases | Q27937990 | ||
MSS4, a phosphatidylinositol-4-phosphate 5-kinase required for organization of the actin cytoskeleton in Saccharomyces cerevisiae. | Q27939032 | ||
The stress-activated phosphatidylinositol 3-phosphate 5-kinase Fab1p is essential for vacuole function in S. cerevisiae | Q27939343 | ||
Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting | Q27940116 | ||
PIKfyve, a mammalian ortholog of yeast Fab1p lipid kinase, synthesizes 5-phosphoinositides. Effect of insulin | Q28140455 | ||
PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cells | Q28236975 | ||
A new pathway for synthesis of phosphatidylinositol-4,5-bisphosphate | Q28254402 | ||
Type I phosphatidylinositol-4-phosphate 5-kinases. Cloning of the third isoform and deletion/substitution analysis of members of this novel lipid kinase family | Q28267069 | ||
FYVE fingers bind PtdIns(3)P | Q28279043 | ||
Endosomal localization of the autoantigen EEA1 is mediated by a zinc-binding FYVE finger | Q28289331 | ||
Pathway of phosphatidylinositol(3,4,5)-trisphosphate synthesis in activated neutrophils | Q28327099 | ||
Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reaction | Q28378871 | ||
Phosphatidylinositol-4-phosphate 5-kinase isozymes catalyze the synthesis of 3-phosphate-containing phosphatidylinositol signaling molecules | Q28640210 | ||
Type I phosphatidylinositol-4-phosphate 5-kinases synthesize the novel lipids phosphatidylinositol 3,5-bisphosphate and phosphatidylinositol 5-phosphate | Q28678918 | ||
P433 | issue | 48 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | Schizosaccharomyces pombe | Q2236682 |
P1104 | number of pages | 8 | |
P304 | page(s) | 33905-33912 | |
P577 | publication date | 1999-11-01 | |
P1433 | published in | Journal of Biological Chemistry | Q867727 |
P1476 | title | Complementation analysis in PtdInsP kinase-deficient yeast mutants demonstrates that Schizosaccharomyces pombe and murine Fab1p homologues are phosphatidylinositol 3-phosphate 5-kinases | |
P478 | volume | 274 |
Q36761494 | A conspicuous connection: structure defines function for the phosphatidylinositol-phosphate kinase family. |
Q24559992 | A mammalian ortholog of Saccharomyces cerevisiae Vac14 that associates with and up-regulates PIKfyve phosphoinositide 5-kinase activity |
Q24645971 | A selective PIKfyve inhibitor blocks PtdIns(3,5)P(2) production and disrupts endomembrane transport and retroviral budding |
Q34368311 | Acquisition of unprecedented phosphatidylinositol 3,5-bisphosphate rise in hyperosmotically stressed 3T3-L1 adipocytes, mediated by ArPIKfyve-PIKfyve pathway |
Q42157829 | AtPIP5K1, an Arabidopsis thaliana phosphatidylinositol phosphate kinase, synthesizes PtdIns(3,4)P(2) and PtdIns(4,5)P(2) in vitro and is inhibited by phosphorylation |
Q24336059 | Binding of Vac14 to neuronal nitric oxide synthase: Characterisation of a new internal PDZ-recognition motif |
Q24532611 | Cellular functions of phosphatidylinositol 3-phosphate and FYVE domain proteins |
Q24291835 | Characterization of MTMR3. an inositol lipid 3-phosphatase with novel substrate specificity |
Q34171101 | Distinct pathogenic processes between Fig4-deficient motor and sensory neurons. |
Q39258904 | Essential roles of PIKfyve and PTEN on phagosomal phosphatidylinositol 3-phosphate dynamics |
Q41066260 | Essential roles of class E Vps proteins for sorting into multivesicular bodies in Schizosaccharomyces pombe |
Q35175628 | Exploring phosphatidylinositol 5-phosphate 4-kinase function |
Q34102439 | Functional dissection of lipid and protein kinase signals of PIKfyve reveals the role of PtdIns 3,5-P2 production for endomembrane integrity |
Q40767356 | Identification of a new polyphosphoinositide in plants, phosphatidylinositol 5-monophosphate (PtdIns5P), and its accumulation upon osmotic stress |
Q35145808 | Identification of new players in cell division, DNA damage response, and morphogenesis through construction of Schizosaccharomyces pombe deletion strains |
Q24617439 | In vivo, Pikfyve generates PI(3,5)P2, which serves as both a signaling lipid and the major precursor for PI5P. |
Q24620024 | Inhibition of the PtdIns(5) kinase PIKfyve disrupts intracellular replication of Salmonella |
Q26852772 | Inositol lipids: from an archaeal origin to phosphatidylinositol 3,5-bisphosphate faults in human disease |
Q34844493 | Inositol phospholipid metabolism in Arabidopsis. Characterized and putative isoforms of inositol phospholipid kinase and phosphoinositide-specific phospholipase C. |
Q42607479 | Isolation of suppressor mutants of phosphatidylinositol 3-phosphate 5-kinase deficient cells in Schizosaccharomyces pombe |
Q35168572 | Lipid kinases are essential for apicoplast homeostasis in Toxoplasma gondii |
Q28511012 | Localization and insulin-regulated relocation of phosphoinositide 5-kinase PIKfyve in 3T3-L1 adipocytes |
Q24678783 | Loss of Vac14, a regulator of the signaling lipid phosphatidylinositol 3,5-bisphosphate, results in neurodegeneration in mice. |
Q50530834 | Loss-of-function and gain-of-function mutations in FAB1A/B impair endomembrane homeostasis, conferring pleiotropic developmental abnormalities in Arabidopsis. |
Q50730452 | MORN motifs in plant PIPKs are involved in the regulation of subcellular localization and phospholipid binding. |
Q28210351 | Mammalian cell morphology and endocytic membrane homeostasis require enzymatically active phosphoinositide 5-kinase PIKfyve |
Q37161706 | Mechanism of substrate specificity of phosphatidylinositol phosphate kinases |
Q34572888 | Nuclear phosphoinositides could bring FYVE alive. |
Q37766113 | One lipid, multiple functions: how various pools of PI(4,5)P(2) are created in the plasma membrane |
Q44908072 | OsPIPK 1, a rice phosphatidylinositol monophosphate kinase, regulates rice heading by modifying the expression of floral induction genes |
Q27930743 | Osmotic stress-induced increase of phosphatidylinositol 3,5-bisphosphate requires Vac14p, an activator of the lipid kinase Fab1p |
Q37275823 | Overexpression of PPK-1, the Caenorhabditis elegans Type I PIP kinase, inhibits growth cone collapse in the developing nervous system and causes axonal degeneration in adults |
Q34285811 | Overexpression of the amplified Pip4k2beta gene from 17q11-12 in breast cancer cells confers proliferation advantage |
Q50293910 | PI3P is phosphorylated to PI(3,5)P2 by PIKFYVE at the Golgi membrane |
Q28258731 | PIKfyve negatively regulates exocytosis in neurosecretory cells |
Q41852844 | PIKfyve regulation of endosome-linked pathways |
Q24652827 | PIKfyve: Partners, significance, debates and paradoxes |
Q26823539 | Phosphatidylinositol 3,5-bisphosphate: low abundance, high significance |
Q34987225 | Phosphatidylinositol 3,5-bisphosphate: metabolism and function |
Q38174542 | Phosphatidylinositol 5-phosphate: a nuclear stress lipid and a tuner of membranes and cytoskeleton dynamics. |
Q34264164 | Phosphatidylinositol Phosphate Kinases Put PI4,5P 2 in Its Place |
Q37314660 | Phosphoinositides and the endocytic pathway |
Q27012953 | Phosphoinositides: tiny lipids with giant impact on cell regulation |
Q36257177 | Plentiful PtdIns5P from scanty PtdIns(3,5)P2 or from ample PtdIns? PIKfyve-dependent models: Evidence and speculation (response to: DOI 10.1002/bies.201300012). |
Q24316670 | PtdIns-specific MPR pathway association of a novel WD40 repeat protein, WIPI49 |
Q35763394 | PtdIns5P: news and views of its appearance, disappearance and deeds |
Q47139214 | Radiolabeling and Quantification of Cellular Levels of Phosphoinositides by High Performance Liquid Chromatography-coupled Flow Scintillation |
Q43694028 | Rapid structural changes and acidification of guard cell vacuoles during stomatal closure require phosphatidylinositol 3,5-bisphosphate |
Q42826889 | Selective insulin-induced activation of class I(A) phosphoinositide 3-kinase in PIKfyve immune complexes from 3T3-L1 adipocytes |
Q33954578 | Sorting in the endosomal system in yeast and animal cells. |
Q77322068 | Stereo-specific substrate recognition by phosphatidylinositol phosphate kinases is swapped by changing a single amino acid residue |
Q36542078 | Supervised membrane swimming: small G-protein lifeguards regulate PIPK signalling and monitor intracellular PtdIns(4,5)P2 pools. |
Q27936381 | Svp1p defines a family of phosphatidylinositol 3,5-bisphosphate effectors |
Q34089143 | Synthesis and biological evaluation of phosphatidylinositol phosphate affinity probes |
Q36768641 | Synthesis and function of membrane phosphoinositides in budding yeast, Saccharomyces cerevisiae |
Q97069589 | TMEM16K is an interorganelle regulator of endosomal sorting |
Q33294829 | The Princeton Protein Orthology Database (P-POD): a comparative genomics analysis tool for biologists |
Q24301637 | The mammalian phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) regulates endosome-to-TGN retrograde transport. |
Q28219187 | The phox homology (PX) domain-dependent, 3-phosphoinositide-mediated association of sorting nexin-1 with an early sorting endosomal compartment is required for its ability to regulate epidermal growth factor receptor degradation |
Q41018413 | The serum- and glucocorticoid-inducible kinases SGK1 and SGK3 regulate hERG channel expression via ubiquitin ligase Nedd4-2 and GTPase Rab11. |
Q33896654 | Type I phosphatidylinositol 4-phosphate 5-kinase directly interacts with ADP-ribosylation factor 1 and is responsible for phosphatidylinositol 4,5-bisphosphate synthesis in the golgi compartment. |
Q43505527 | Type Ialpha phosphatidylinositol 4-phosphate 5-kinase is a putative target for increased intracellular phosphatidic acid |
Q27932192 | Vac14 controls PtdIns(3,5)P(2) synthesis and Fab1-dependent protein trafficking to the multivesicular body |
Q44564199 | YXXM motifs in the PDGF-beta receptor serve dual roles as phosphoinositide 3-kinase binding motifs and tyrosine-based endocytic sorting signals |
Q35582986 | Yeast Vacuole Inheritance and Dynamics |
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