review article | Q7318358 |
scholarly article | Q13442814 |
P2093 | author name string | S. J. Harper | |
P. LoGrasso | |||
P2860 | cites work | The JIP group of mitogen-activated protein kinase scaffold proteins | Q22010547 |
Interaction of c-Jun amino-terminal kinase interacting protein-1 with p190 rhoGEF and its localization in differentiated neurons | Q22010849 | ||
Signal transduction by tumor necrosis factor mediated by JNK protein kinases | Q24308037 | ||
JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain | Q24308838 | ||
Identification of mitogen-activated protein (MAP) kinase-activated protein kinase-3, a novel substrate of CSBP p38 MAP kinase | Q24309889 | ||
p493F12 kinase: a novel MAP kinase expressed in a subset of neurons in the human nervous system | Q24310112 | ||
A protein kinase involved in the regulation of inflammatory cytokine biosynthesis | Q24311139 | ||
Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms | Q24312029 | ||
Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2 | Q24313872 | ||
Selective interaction of JNK protein kinase isoforms with transcription factors | Q24317346 | ||
Characterization of the structure and function of a new mitogen-activated protein kinase (p38beta) | Q24321919 | ||
Characterization of the structure and function of a novel MAP kinase kinase (MKK6) | Q24336966 | ||
Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2 | Q24532154 | ||
ATF-2 contains a phosphorylation-dependent transcriptional activation domain | Q24568315 | ||
Grb2-associated binder-1 mediates phosphatidylinositol 3-kinase activation and the promotion of cell survival by nerve growth factor | Q24648537 | ||
MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway | Q24650627 | ||
A splicing variant of a death domain protein that is regulated by a mitogen-activated kinase is a substrate for c-Jun N-terminal kinase in the human central nervous system | Q24681222 | ||
Crystal structure of JNK3: a kinase implicated in neuronal apoptosis | Q27765333 | ||
Neurotrophin signal transduction in the nervous system | Q27876223 | ||
AKT/PKB and other D3 phosphoinositide-regulated kinases: kinase activation by phosphoinositide-dependent phosphorylation | Q28139447 | ||
A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells | Q28237789 | ||
Characterization of the mitogen-activated protein kinase kinase 4 (MKK4)/c-Jun NH2-terminal kinase 1 and MKK3/p38 pathways regulated by MEK kinases 2 and 3. MEK kinase 3 activates MKK3 but does not cause activation of p38 kinase in vivo | Q28238990 | ||
JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation | Q28243308 | ||
Identification of c-Jun NH2-terminal protein kinase (JNK)-activating kinase 2 as an activator of JNK but not p38 | Q28249893 | ||
Nuclear accumulation of NFAT4 opposed by the JNK signal transduction pathway | Q28255002 | ||
JNK1, JNK2 and JNK3 are p53 N-terminal serine 34 kinases | Q28256056 | ||
Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP Kinase | Q28280649 | ||
A mammalian scaffold complex that selectively mediates MAP kinase activation | Q28281953 | ||
Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine | Q28287650 | ||
Deficiency of the stress kinase p38alpha results in embryonic lethality: characterization of the kinase dependence of stress responses of enzyme-deficient embryonic stem cells | Q28343994 | ||
JNK is required for effector T-cell function but not for T-cell activation | Q28507174 | ||
Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene | Q28507982 | ||
Molecular cloning of multiple splicing variants of JIP-1 preferentially expressed in brain | Q28571844 | ||
Differential expression of SAPK isoforms in the rat brain. An in situ hybridisation study in the adult rat brain and during post-natal development | Q28575489 | ||
c-Jun N-terminal kinase (JNK) and JNK interacting protein response in rat brain after transient middle cerebral artery occlusion | Q28576960 | ||
Spatial, temporal and subcellular localization of islet-brain 1 (IB1), a homologue of JIP-1, in mouse brain | Q28581943 | ||
A cytoplasmic inhibitor of the JNK signal transduction pathway | Q28586970 | ||
Loss of neurofibromin results in neurotrophin-independent survival of embryonic sensory and sympathetic neurons | Q28590132 | ||
MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis | Q28593865 | ||
Characterization of the structure and function of the fourth member of p38 group mitogen-activated protein kinases, p38delta | Q28646538 | ||
Selective activation of p38 mitogen-activated protein (MAP) kinase isoforms by the MAP kinase kinases MKK3 and MKK6 | Q28678886 | ||
Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis | Q29547567 | ||
Cellular survival: a play in three Akts | Q29547806 | ||
Regulation of neuronal survival by the serine-threonine protein kinase Akt | Q29614185 | ||
The stress-activated protein kinase subfamily of c-Jun kinases | Q29620001 | ||
Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain | Q29620169 | ||
SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1 | Q29620495 | ||
Up-regulation of genes involved in cellular stress and apoptosis in a rat model of hippocampal degeneration | Q30835083 | ||
The p38 signal transduction pathway: activation and function | Q33838955 | ||
Distinct mechanisms underlie neurotoxin-mediated cell death in cultured dopaminergic neurons. | Q48287496 | ||
Expression of c-fos, c-jun, and c-jun N-terminal kinase (JNK) in a developmental model of induced apoptotic death in neurons of the substantia nigra | Q48292836 | ||
PACAP protects hippocampal neurons against apoptosis: involvement of JNK/SAPK signaling pathway | Q48295219 | ||
Inhibition of phosphatidylinositol 3-kinase activity elevates c-Jun N-terminal kinase activity in apoptosis of cultured cerebellar granule neurons | Q48312815 | ||
JNK and p38 stresskinases--degenerative effectors of signal-transduction-cascades in the nervous system | Q33887876 | ||
Activation of JNK3 alpha 1 requires both MKK4 and MKK7: kinetic characterization of in vitro phosphorylated JNK3 alpha 1. | Q33893183 | ||
Identification and characterization of a predominant isoform of human MKK3. | Q34416895 | ||
Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation | Q34419537 | ||
p38-2, a novel mitogen-activated protein kinase with distinct properties. | Q34433633 | ||
MAPKAPK5, a novel mitogen-activated protein kinase (MAPK)-activated protein kinase, is a substrate of the extracellular-regulated kinase (ERK) and p38 kinase | Q34457998 | ||
Phosphatidylinositol 3-kinase and Akt protein kinase are necessary and sufficient for the survival of nerve growth factor-dependent sympathetic neurons. | Q34462515 | ||
Targeted disruption of the MKK4 gene causes embryonic death, inhibition of c-Jun NH2-terminal kinase activation, and defects in AP-1 transcriptional activity | Q36074411 | ||
Altered gene expression in neurons during programmed cell death: identification of c-jun as necessary for neuronal apoptosis | Q36235038 | ||
c-Jun N-terminal phosphorylation correlates with activation of the JNK subgroup but not the ERK subgroup of mitogen-activated protein kinases | Q36667357 | ||
MKK7 is a stress-activated mitogen-activated protein kinase kinase functionally related to hemipterous. | Q36884483 | ||
Peripheral axotomy induces long-term c-Jun amino-terminal kinase-1 activation and activator protein-1 binding activity by c-Jun and junD in adult rat dorsal root ganglia In vivo. | Q37019949 | ||
Nerve growth factor activates extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways to stimulate CREB serine 133 phosphorylation | Q39631004 | ||
Molecular determinants that mediate selective activation of p38 MAP kinase isoforms | Q40387373 | ||
Early events in neurotrophin signalling via Trk and p75 receptors | Q40957968 | ||
MLK-3 activates the SAPK/JNK and p38/RK pathways via SEK1 and MKK3/6 | Q41079070 | ||
Molecular cloning and characterization of a novel p38 mitogen-activated protein kinase | Q41091097 | ||
p53 is essential for developmental neuron death as regulated by the TrkA and p75 neurotrophin receptors | Q42071377 | ||
Involvement of ras p21 in neurotrophin-induced response of sensory, but not sympathetic neurons | Q42181592 | ||
Neurotrophic 3,9-bis[(alkylthio)methyl]-and-bis(alkoxymethyl)-K-252a derivatives | Q42439874 | ||
Role of the Jun kinase pathway in the regulation of c-Jun expression and apoptosis in sympathetic neurons. | Q42450734 | ||
Preservation of cholinergic activity and prevention of neuron death by CEP-1347/KT-7515 following excitotoxic injury of the nucleus basalis magnocellularis. | Q42466285 | ||
Chronic sparing of delayed alternation performance and choline acetyltransferase activity by CEP-1347/KT-7515 in rats with lesions of nucleus basalis magnocellularis | Q42466288 | ||
Activity and expression of JNK1, p38 and ERK kinases, c-Jun N-terminal phosphorylation, and c-jun promoter binding in the adult rat brain following kainate-induced seizures | Q42473299 | ||
Colocalisation and covariation of c-JUN transcription factor with galanin in primary afferent neurons and with CGRP in spinal motoneurons following transection of rat sciatic nerve | Q42482823 | ||
A role for MAPK/ERK in sympathetic neuron survival: protection against a p53-dependent, JNK-independent induction of apoptosis by cytosine arabinoside. | Q42536958 | ||
Requirement of p38 mitogen-activated protein kinase for neuronal differentiation in PC12 cells | Q42539781 | ||
Opposite functions of jun-B and c-jun in growth regulation and neuronal differentiation | Q42813493 | ||
Lasting N-terminal phosphorylation of c-Jun and activation of c-Jun N-terminal kinases after neuronal injury. | Q42828653 | ||
Study of proline-directed protein kinases involved in phosphorylation of the heavy neurofilament subunit. | Q42833278 | ||
Depolarization and neurotrophins converge on the phosphatidylinositol 3-kinase-Akt pathway to synergistically regulate neuronal survival | Q42911158 | ||
Neurotrophic molecules: strategies for designing effective therapeutic molecules in neurodegeneration | Q45890180 | ||
The primary structure of p38 gamma: a new member of p38 group of MAP kinases | Q46763189 | ||
Apoptosis of cerebellar granule cells induced by serum withdrawal, glutamate or beta-amyloid, is independent of Jun kinase or p38 mitogen activated protein kinase activation. | Q47719854 | ||
CEP-1347/KT7515, a JNK pathway inhibitor, supports the in vitro survival of chick embryonic neurons. | Q47959232 | ||
Progress toward understanding the molecular mechanisms of neurotrophic factor signalling | Q48026353 | ||
Bidirectional regulation of p38 kinase and c-Jun N-terminal protein kinase by insulin-like growth factor-I. | Q48034415 | ||
Inhibitors of mitogen-activated protein kinases protect axotomized developing neurons | Q48087861 | ||
Nerve growth factor-induced PKB/Akt activity is sustained by phosphoinositide 3-kinase dependent and independent signals in sympathetic neurons | Q48144694 | ||
An inhibitor of p38 and JNK MAP kinases prevents activation of caspase and apoptosis of cultured cerebellar granule neurons | Q48219466 | ||
The Jnk1 and Jnk2 protein kinases are required for regional specific apoptosis during early brain development | Q48219557 | ||
p38 kinase is activated in the Alzheimer's disease brain | Q48227440 | ||
Human c-Jun N-terminal kinase expression and activation in the nervous system | Q48249466 | ||
Is c-Jun involved in nerve cell death following status epilepticus and hypoxic-ischaemic brain injury? | Q48277117 | ||
Axotomy-induced c-JUN expression in young medial septal neurons is regulated by nerve growth factor | Q48382326 | ||
Activation of p38MAPK in microglia after ischemia. | Q48497493 | ||
Phosphorylation of c-Jun is necessary for apoptosis induced by survival signal withdrawal in cerebellar granule neurons. | Q48548127 | ||
Localization of the messenger RNA for the c-Jun NH2-terminal kinase kinase in the adult and developing rat brain: an in situ hybridization study | Q48633600 | ||
Activation and involvement of p38 mitogen-activated protein kinase in glutamate-induced apoptosis in rat cerebellar granule cells | Q48656057 | ||
Glutamate, but not dopamine, stimulates stress-activated protein kinase and AP-1-mediated transcription in striatal neurons. | Q48707018 | ||
Medial septal cholinergic neurons express c-Jun but do not undergo DNA fragmentation after fornix-fimbria transections | Q48826522 | ||
Selective expression of the immediate early gene c-jun in axotomized rat medial septal neurons is not related to neuronal degeneration. | Q49085222 | ||
Transection of rat fimbria-fornix induces lasting expression of c-Jun protein in axotomized septal neurons immunonegative for choline acetyltransferase and nitric oxide synthase. | Q50760566 | ||
Comparison between the timing of JNK activation, c-Jun phosphorylation, and onset of death commitment in sympathetic neurones. | Q51101721 | ||
Nerve growth factor induces survival and differentiation through two distinct signaling cascades in PC12 cells. | Q52177288 | ||
Ras regulates sympathetic neuron survival by suppressing the p53-mediated cell death pathway | Q57042606 | ||
Integration of MAP kinase signal transduction pathways at the serum response element | Q58415341 | ||
The anti-apoptotic protein ITA is essential for NGF-mediated survival of embryonic chick neurons | Q60215412 | ||
Aberrant neurofilament phosphorylation in sensory neurons of rats with diabetic neuropathy | Q60227864 | ||
Differential transcription and translation of immediate early genes in the gerbil hippocampus after transient global ischemia | Q70501469 | ||
Inhibition of p38 mitogen-activated protein kinase by insulin in cultured fetal neurons | Q71070351 | ||
Mitogen-activated protein kinase-independent pathways mediate the effects of nerve growth factor and cAMP on neuronal survival | Q71246241 | ||
Inhibition of p42 and p44 mitogen-activated protein kinase activity by PD98059 does not suppress nerve growth factor-induced survival of sympathetic neurones | Q71667558 | ||
Aberrant stress-induced phosphorylation of perikaryal neurofilaments | Q71825265 | ||
A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death | Q72232625 | ||
Neutralizing anti-p21ras Fabs suppress rat sympathetic neuron survival induced by NGF, LIF, CNTF and cAMP | Q72254074 | ||
Differential regulation of c-JUN expression in rat retinal ganglion cells after proximal and distal optic nerve transection | Q72396757 | ||
Expression of c-Jun as a response to dorsal root and peripheral nerve section in damaged and adjacent intact primary sensory neurons in the rat | Q72657041 | ||
Regulation of the transcription factor c-JUN by nerve growth factor in adult sensory neurons | Q72903790 | ||
p38 map kinase substrate specificity differs greatly for protein and peptide substrates | Q73165790 | ||
Identification of two distinct regions of p38 MAPK required for substrate binding and phosphorylation | Q73226384 | ||
Expression of cell death-associated phospho-c-Jun and p53-activated gene 608 in hippocampal CA1 neurons following global ischemia | Q73226725 | ||
Mediation by a CREB family transcription factor of NGF-dependent survival of sympathetic neurons | Q73278662 | ||
Selective expression of JNK isoforms and stress-specific JNK activity in different neural cell lines | Q73387849 | ||
Inhibition of the cardiac p38-MAPK pathway by SB203580 delays ischemic cell death | Q73531785 | ||
Apoptosis induced by withdrawal of trophic factors is mediated by p38 mitogen-activated protein kinase | Q73575389 | ||
Kinetic mechanism for p38 MAP kinase | Q73611887 | ||
Apoptosis and impaired axonal regeneration of sensory neurons after nerve crush in diabetic rats | Q73658201 | ||
Differential activation of MAPK/ERK and p38/SAPK in neurones and glia following focal cerebral ischaemia in the rat | Q73800967 | ||
Synergetic activation of p38 mitogen-activated protein kinase and caspase-3-like proteases for execution of calyculin A-induced apoptosis but not N-methyl-d-aspartate-induced necrosis in mouse cortical neurons | Q73812100 | ||
Motoneuron apoptosis is blocked by CEP-1347 (KT 7515), a novel inhibitor of the JNK signaling pathway | Q73977274 | ||
CEP-1347 increases ChAT activity in culture and promotes cholinergic neurone survival following fimbria-fornix lesion | Q74102463 | ||
Apoptosis of central and peripheral neurons can be prevented with cyclin-dependent kinase/mitogen-activated protein kinase inhibitors | Q74384001 | ||
Inhibitors of p38 mitogen-activated protein kinase promote neuronal survival in vitro | Q74555031 | ||
Synergistic activation of SAPK1/JNK1 by two MAP kinase kinases in vitro | Q77796005 | ||
The inhibitors of apoptosis (IAPs) and their emerging role in cancer | Q77900361 | ||
Design and synthesis of potent, selective, and orally bioavailable tetrasubstituted imidazole inhibitors of p38 mitogen-activated protein kinase | Q77906539 | ||
Specific activation of the p38 mitogen-activated protein kinase signaling pathway and induction of neurite outgrowth in PC12 cells by bone morphogenetic protein-2 | Q78208149 | ||
P433 | issue | 5 | |
P304 | page(s) | 299–310 | |
P577 | publication date | 2001-05-01 | |
P1433 | published in | Cellular Signalling | Q1524097 |
P1476 | title | Signalling for survival and death in neurones: the role of stress-activated kinases, JNK and p38 | |
P478 | volume | 13 |