Enhanced antitumor efficacy of a vascular disrupting agent combined with an antiangiogenic in a rat liver tumor model evaluated by multiparametric MRI

scientific article (publication date: 2012)

Enhanced antitumor efficacy of a vascular disrupting agent combined with an antiangiogenic in a rat liver tumor model evaluated by multiparametric MRI is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2012PLoSO...741140C
P356DOI10.1371/JOURNAL.PONE.0041140
P932PMC publication ID3399789
P698PubMed publication ID22815943
P5875ResearchGate publication ID229427945

P50authorCatherine VerfaillieQ615166
P2093author name stringFeng Chen
Jie Yu
Marlein Miranda Cona
Raymond Oyen
Yansheng Jiang
Yicheng Ni
Yuanbo Feng
Junjie Li
Bart De Geest
Yingmei Feng
Guy Marchal
Huaijun Wang
Frederik De Keyzer
Kaier Zheng
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Complications from vascular disrupting agents and angiogenesis inhibitors: aberrant control of hemostasis and thrombosisQ28222601
Normalization of tumor vasculature: an emerging concept in antiangiogenic therapyQ29547379
Osteogenic sarcoma: noninvasive in vivo assessment of tumor necrosis with diffusion-weighted MR imagingQ32153909
Thalidomide in solid tumours: the resurrection of an old drugQ33208578
Thalidomide radiosensitizes tumors through early changes in the tumor microenvironment.Q33211653
Anti-vascular agent Combretastatin A-4-P modulates hypoxia inducible factor-1 and gene expressionQ33265941
Thalidomide stimulates vessel maturation and reduces epistaxis in individuals with hereditary hemorrhagic telangiectasiaQ34021937
A review of angiogenesis and antiangiogenic therapy with thalidomide in multiple myeloma.Q34046046
The unique characteristics of tumor vasculature and preclinical evidence for its selective disruption by Tumor-Vascular Disrupting AgentsQ34122191
Multiplexed imaging in cancer diagnosis: applications and future advancesQ36143279
Disrupting tumour blood vesselsQ36146900
Repopulation of cancer cells during therapy: an important cause of treatment failureQ36167592
Non-invasive assessment of vessel morphology and function in tumors by magnetic resonance imagingQ36739621
Antivascular actions of microtubule-binding drugsQ37349697
Contribution of granulocyte colony-stimulating factor to the acute mobilization of endothelial precursor cells by vascular disrupting agents.Q37378187
Microtubule depolymerizing vascular disrupting agents: novel therapeutic agents for oncology and other pathologiesQ37534993
Liver tumor model with implanted rhabdomyosarcoma in rats: MR imaging, microangiography, and histopathologic analysisQ39748901
A novel anticancer effect of thalidomide: inhibition of intercellular adhesion molecule-1-mediated cell invasion and metastasis through suppression of nuclear factor-kappaB.Q40200899
Therapy-induced acute recruitment of circulating endothelial progenitor cells to tumors.Q40228810
Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation: role of oxygenation, angiopoietin-1, and matrix metalloproteinases.Q40479307
ZD6126: a novel small molecule vascular targeting agentQ40686415
High resolution measurement of cerebral blood flow using intravascular tracer bolus passages. Part I: Mathematical approach and statistical analysisQ41209024
Modeling tracer kinetics in dynamic Gd-DTPA MR imagingQ41352795
Endothelial-cell proliferation in experimental tumoursQ41502842
Diffusion-weighted magnetic resonance imaging allows noninvasive in vivo monitoring of the effects of combretastatin a-4 phosphate after repeated administrationQ41537813
Targeted therapies: Thalidomide in lung cancer therapy-what have we learned?Q43146801
Efficacy of combined antiangiogenic and vascular disrupting agents in treatment of solid tumorsQ45133701
Treatment of rodent liver tumor with combretastatin a4 phosphate: noninvasive therapeutic evaluation using multiparametric magnetic resonance imaging in correlation with microangiography and histologyQ46228470
Human ApoA-I transfer attenuates transplant arteriosclerosis via enhanced incorporation of bone marrow-derived endothelial progenitor cellsQ46862751
Antiangiogenic combination therapy after local radiotherapy with topotecan radiosensitizer improved quality of life for children with inoperable brainstem gliomasQ48088826
Diffusion weighted imaging in small rodents using clinical MRI scanners.Q53466991
Combretastatin A-4, an agent that displays potent and selective toxicity toward tumor vasculatureQ73352832
Pre-clinical and clinical evaluation of estramustine, docetaxel and thalidomide combination in androgen-independent prostate cancerQ80165576
Multiparametric imaging of tumor response to therapyQ84591883
Cancer models-multiparametric applications of clinical MRI in rodent hepatic tumor modelQ84847970
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectangiogenesis inhibitorQ574834
P304page(s)e41140
P577publication date2012-01-01
P1433published inPLOS OneQ564954
P1476titleEnhanced antitumor efficacy of a vascular disrupting agent combined with an antiangiogenic in a rat liver tumor model evaluated by multiparametric MRI
P478volume7

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cites work (P2860)
Q34849516Combination therapy of VEGF-trap and gemcitabine results in improved anti-tumor efficacy in a mouse lung cancer model
Q36613314Diverse responses to vascular disrupting agent combretastatin a4 phosphate: a comparative study in rats with hepatic and subcutaneous tumor allografts using MRI biomarkers, microangiography, and histopathology
Q35077659Dynamic contrast-enhanced and diffusion-weighted magnetic resonance imaging noninvasive evaluation of vascular disrupting treatment on rabbit liver tumors
Q41549134Micro-HCCs in rats with liver cirrhosis: paradoxical targeting effects with vascular disrupting agent CA4P.
Q50041830Monitoring tumor response to the vascular disrupting agent CKD-516 in a rabbit VX2 intramuscular tumor model using PET/MRI: Simultaneous evaluation of vascular and metabolic parameters
Q89551846Predicting Clinical Efficacy of Vascular Disrupting Agents in Rodent Models of Primary and Secondary Liver Cancers: An Overview with Imaging-Histopathology Correlation
Q37408968Separate calculation of DW-MRI in assessing therapeutic effect in liver tumors in rats
Q36609881Small Molecule Sequential Dual-Targeting Theragnostic Strategy (SMSDTTS): from Preclinical Experiments towards Possible Clinical Anticancer Applications
Q38259982Targeting the Angiopoietin-2/Tie-2 axis in conjunction with VEGF signal interference
Q26774355Tumor resistance to vascular disrupting agents: mechanisms, imaging, and solutions

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