Structural effects and translocation of doxorubicin in a DPPC/Chol bilayer: the role of cholesterol

scientific article (publication date: 20 July 2011)

Structural effects and translocation of doxorubicin in a DPPC/Chol bilayer: the role of cholesterol is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.BPJ.2011.06.015
P932PMC publication ID3136772
P698PubMed publication ID21767490
P5875ResearchGate publication ID51500605

P50authorIgal SzleiferQ38546558
P2093author name stringAllam S Reddy
Tyrone J Yacoub
P2860cites workDrugBank: a knowledgebase for drugs, drug actions and drug targetsQ24650300
GROMACS 4:  Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular SimulationQ27860944
Drug delivery systems: entering the mainstreamQ29618136
Partitioning of nonsteroidal antiinflammatory drugs in lipid membranes: a molecular dynamics simulation study.Q33647834
Optimizing liposomes for delivery of chemotherapeutic agents to solid tumors.Q33784378
Areas of molecules in membranes consisting of mixturesQ34092946
Cholesterol-induced modifications in lipid bilayers: a simulation studyQ34178803
Permeation across hydrated DPPC lipid bilayers: simulation of the titrable amphiphilic drug valproic acidQ34183816
Adriamycin. A new anticancer drug with significant clinical activityQ34699440
On the thermodynamic stability of a charged arginine side chain in a transmembrane helixQ35691013
Distribution and dynamics of adamantanes in a lipid bilayerQ37008274
Ordering effects of cholesterol and its analoguesQ37281808
Targeting anticancer drugs to tumor vasculature using cationic liposomes.Q37718056
Molecular dynamics simulations of salicylate effects on the micro- and mesoscopic properties of a dipalmitoylphosphatidylcholine bilayerQ39408569
Fate and behavior of liposomes in vivo: a review of controlling factorsQ39754313
Molecular dynamics simulations of phospholipid bilayers with cholesterolQ40232945
Distribution of pentachlorophenol in phospholipid bilayers: a molecular dynamics studyQ40268182
The hepatic pharmacokinetics of doxorubicin and liposomal doxorubicinQ44982069
The role of lipid composition for insertion and stabilization of amino acids in membranes.Q46007526
A comparison of sulfur mustard and heptane penetrating a dipalmitoylphosphatidylcholine bilayer membraneQ46062082
Mechanism of unassisted ion transport across membrane bilayersQ46146180
Thermodynamic analysis of the effect of cholesterol on dipalmitoylphosphatidylcholine lipid membranesQ46161627
Molecular dynamics - potential of mean force calculations as a tool for understanding ion permeation and selectivity in narrow channelsQ46357860
Transport of anthracyclines and mitoxantrone across membranes by a flip-flop mechanismQ46512279
Behaviour of small solutes and large drugs in a lipid bilayer from computer simulationsQ46830635
Modulating membrane properties: the effect of trehalose and cholesterol on a phospholipid bilayerQ46866159
Flip-flop of doxorubicin across erythrocyte and lipid membranes.Q48536073
An improved united atom force field for simulation of mixed lipid bilayers.Q51798189
Phase transitions in phospholipid vesicles Fluorescence polarization and permeability measurements concerning the effect of temperature and cholesterolQ52938610
Steroid structural requirements for interaction of ostreolysin, a lipid-raft binding cytolysin, with lipid monolayers and bilayersQ57359284
Influence of vesicle size, lipid composition, and drug-to-lipid ratio on the biological activity of liposomal doxorubicin in miceQ69746848
Cholesterol content of small unilamellar liposomes controls phospholipid loss to high density lipoproteins in the presence of serumQ71142092
Prolonged circulation time and enhanced accumulation in malignant exudates of doxorubicin encapsulated in polyethylene-glycol coated liposomesQ72785658
Permeability of lipid bilayer to anthracycline derivatives. Role of the bilayer composition and of the temperatureQ74094233
A comparison of methods to compute the potential of mean forceQ79387967
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectbiophysicsQ7100
doxorubicinQ18936
P1104number of pages8
P304page(s)378-385
P577publication date2011-07-01
P1433published inBiophysical JournalQ2032955
P1476titleStructural effects and translocation of doxorubicin in a DPPC/Chol bilayer: the role of cholesterol
P478volume101

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cites work (P2860)
Q61795933A computational study of Anthracyclines interacting with lipid bilayers: Correlation of membrane insertion rates, orientation effects and localisation with cytotoxicity
Q50921814Combination of anti-hypertensive drugs: a molecular dynamics simulation study.
Q57368201Development of tailored SPION-PNIPAM nanoparticles by ATRP for dually responsive doxorubicin delivery and MR imaging
Q41108256Influence of doxorubicin on model cell membrane properties: insights from in vitro and in silico studies
Q53444089Liposomal Co-Encapsulation of Two Novel Europium Complexes and Doxorubicin: Fluorescence Study.
Q63547192Multiscale Simulations of Biological Membranes: The Challenge To Understand Biological Phenomena in a Living Substance
Q53483815Predicting solute partitioning in lipid bilayers: Free energies and partition coefficients from molecular dynamics simulations and COSMOmic.
Q41157019Study of curcumin behavior in two different lipid bilayer models of liposomal curcumin using molecular dynamics simulation.
Q47278974Study of the properties of doxorubicin-resistant cells affected by acute leucosis.
Q41633843The cellular membrane as a mediator for small molecule interaction with membrane proteins
Q40643109Thermodynamics of cell-penetrating HIV1 TAT peptide insertion into PC/PS/CHOL model bilayers through transmembrane pores: the roles of cholesterol and anionic lipids

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