Immunoproteomics analysis of the murine antibody response to vaccination with an improved Francisella tularensis live vaccine strain (LVS)

scientific article (publication date: 2 April 2010)

Immunoproteomics analysis of the murine antibody response to vaccination with an improved Francisella tularensis live vaccine strain (LVS) is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2010PLoSO...510000T
P356DOI10.1371/JOURNAL.PONE.0010000
P932PMC publication ID2848853
P698PubMed publication ID20368994
P5875ResearchGate publication ID43023943

P2093author name stringJ Wayne Conlan
Susan M Twine
Kelly M Fulton
Robert V House
Mireille D Petit
P2860cites workImmunodominant Francisella tularensis antigens identified using proteome microarray.Q51579914
Susceptibility of various mouse strains to systemically- or aerosol-initiated tularemia by virulent type A Francisella tularensis before and after immunization with the attenuated live vaccine strain of the pathogen.Q53895179
Rapid immunodetection on polyvinylidene fluoride membrane blots without blockingQ70817174
The immune response against Francisella tularensis live vaccine strain in Lps(n) and Lps(d) miceQ71661740
Tularemia in BALB/c and C57BL/6 mice vaccinated with Francisella tularensis LVS and challenged intradermally, or by aerosol with virulent isolates of the pathogen: protection varies depending on pathogen virulence, route of exposure, and host genetiQ73816633
Tularemia: a perusal of three hundred thirty-nine casesQ76481815
Studies with tularemia vaccines in volunteers. III. Serologic aspects following intracutaneous or respiratory challenge in both vaccinated and nonvaccinated volunteersQ79015674
Tularemia vaccine study. II. Respiratory challengeQ79015704
Tularemia vaccine study. I. Intracutaneous challengeQ79015708
Immunoproteomic analysis of the murine antibody response to successful and failed immunization with live anti-Francisella vaccinesQ79744513
Aerosol-, but not intradermal-immunization with the live vaccine strain of Francisella tularensis protects mice against subsequent aerosol challenge with a highly virulent type A strain of the pathogen by an alphabeta T cell- and interferon gamma- dQ81488446
Natural killer and CD8 T cells dominate the response by human peripheral blood mononuclear cells to inactivated Francisella tularensis live vaccine strainQ82138765
In vivo proteomic analysis of the intracellular bacterial pathogen, Francisella tularensis, isolated from mouse spleenQ83859430
Proteomic analysis of the Escherichia coli outer membrane.Q30870112
Proteomic analysis of anti-Francisella tularensis LVS antibody response in murine model of tularemia.Q33215033
Identification of immunoreactive antigens in membrane proteins enriched fraction from Francisella tularensis LVS.Q33269973
Intranasal vaccination induces protective immunity against intranasal infection with virulent Francisella tularensis biovar AQ33768818
CD4+ and CD8+ T-cell-dependent and -independent host defense mechanisms can operate to control and resolve primary and secondary Francisella tularensis LVS infection in miceQ34549016
Low dose aerosol infection of mice with virulent type A Francisella tularensis induces severe thymus atrophy and CD4+CD8+ thymocyte depletionQ35025586
A vaccine for tularaemiaQ35164813
Vaccines against Francisella tularensis--past, present and futureQ35791781
Tularemia vaccine: past, present and futureQ36147043
CD4-CD8- T cells control intracellular bacterial infections both in vitro and in vivoQ36403153
Vaccines against Francisella tularensisQ36774993
Animal models of Francisella tularensis infectionQ36775013
An improved Francisella tularensis live vaccine strain (LVS) is well tolerated and highly immunogenic when administered to rabbits in escalating doses using various immunization routesQ37183341
Molecular immunology of experimental primary tularemia in mice infected by respiratory or intradermal routes with type A Francisella tularensisQ37275515
Humoral and cell-mediated immunity to the intracellular pathogen Francisella tularensis.Q37287818
Safety, reactogenicity and immunogenicity of Francisella tularensis live vaccine strain in humansQ37305453
Nature of protective immunity to Francisella tularensis.Q38663749
Susceptibility to secondary Francisella tularensis live vaccine strain infection in B-cell-deficient mice is associated with neutrophilia but not with defects in specific T-cell-mediated immunityQ39517769
In vivo clearance of an intracellular bacterium, Francisella tularensis LVS, is dependent on the p40 subunit of interleukin-12 (IL-12) but not on IL-12 p70.Q39654574
Aerogenic immunization of man with live Tularemia vaccineQ40720507
Multiple T cell subsets control Francisella tularensis LVS intracellular growth without stimulation through macrophage interferon gamma receptorsQ42047613
Mapping of immunoreactive antigens of Francisella tularensis live vaccine strainQ44068981
Francisella tularensis proteome: low levels of ASB-14 facilitate the visualization of membrane proteins in total protein extractsQ46741767
Various membrane proteins of Francisella tularensis induce interferon-gamma production in both CD4+ and CD8+ T cells of primed humansQ46892532
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectFrancisella tularensisQ1003460
attenuated vaccineQ1810913
antibodyQ79460
P304page(s)e10000
P577publication date2010-04-02
P1433published inPLOS OneQ564954
P1476titleImmunoproteomics analysis of the murine antibody response to vaccination with an improved Francisella tularensis live vaccine strain (LVS)
P478volume5

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cites work (P2860)
Q28394941Antibodies for biodefense
Q27684471B-Cell Epitopes in GroEL of Francisella tularensis
Q83831171BALB/c mice, but not C57BL/6 mice immunized with a ΔclpB mutant of Francisella tularensis subspecies tularensis are protected against respiratory challenge with wild-type bacteria: association of protection with post-vaccination and post-challenge i
Q38687410Differential Growth of Francisella tularensis, Which Alters Expression of Virulence Factors, Dominant Antigens, and Surface-Carbohydrate Synthases, Governs the Apparent Virulence of Ft SchuS4 to Immunized Animals
Q35072870Francisella tularensis LVS surface and membrane proteins as targets of effective post-exposure immunization for tularemia
Q35606536Francisella tularensis Vaccines Elicit Concurrent Protective T- and B-Cell Immune Responses in BALB/cByJ Mice
Q40319759Immunoproteomic Analysis of Antibody Response of Rabbit Host Against Heat-Killed Francisella tularensis Live Vaccine Strain
Q35049264Immunoproteomic analysis of proteins expressed by two related pathogens, Burkholderia multivorans and Burkholderia cenocepacia, during human infection
Q35251703Immunoproteomic analysis of the human antibody response to natural tularemia infection with Type A or Type B strains or LVS vaccination
Q36676050Immunoproteomics: the key to discovery of new vaccine antigens against bacterial respiratory infections.
Q30409782Live attenuated mutants of Francisella tularensis protect rabbits against aerosol challenge with a virulent type A strain
Q34023860Pneumonic tularemia in rabbits resembles the human disease as illustrated by radiographic and hematological changes after infection
Q34077689Roles for wbtC, wbtI, and kdtA Genes in Lipopolysaccharide Biosynthesis, Protein Glycosylation, Virulence, and Immunogenicity in Francisella tularensis2 Strain SCHU S4.
Q35029271The francisella tularensis proteome and its recognition by antibodies
Q34180914Tularemia vaccines: recent developments and remaining hurdles