Endovascular therapy yields significantly superior outcomes for large vessel occlusions compared with intravenous thrombolysis: is it time to randomize?

journal article published in 2013

Endovascular therapy yields significantly superior outcomes for large vessel occlusions compared with intravenous thrombolysis: is it time to randomize? is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1136/NEURINTSURG-2012-010429
P2880NIOSHTIC-2 ID20049369
P698PubMed publication ID22842210

P2093author name stringDaniel Rodgers
Gerald R Hobbs
Ansaar T Rai
Jeffrey S Carpenter
Thomas D Roberts
Karthikram Raghuram
P2860cites workEfficacy of Intra-Arterial Fibrinolysis for Acute Ischemic Stroke: Meta-Analysis of Randomized Controlled TrialsQ22306330
Safety and efficacy of mechanical embolectomy in acute ischemic stroke: results of the MERCI trialQ28257163
Mechanical thrombectomy for acute ischemic stroke: final results of the Multi MERCI trialQ28270791
Mechanical thrombectomy of intracranial internal carotid occlusion: pooled results of the MERCI and Multi MERCI Part I trialsQ28291017
SAFETY, EFFECTIVENESS, AND PRACTICALITY OF ENDOVASCULAR THERAPY WITHIN THE FIRST 3 HOURS OF ACUTE ISCHEMIC STROKE ONSETQ29399767
Tissue plasminogen activator for acute ischemic strokeQ29619377
Intra-arterial prourokinase for acute ischemic stroke. The PROACT II study: a randomized controlled trial. Prolyse in Acute Cerebral Thromboembolism.Q33883119
Recommendations for the establishment of primary stroke centers. Brain Attack CoalitionQ33949258
Timing of recanalization after tissue plasminogen activator therapy determined by transcranial doppler correlates with clinical recovery from ischemic strokeQ33991631
Thrombus burden is associated with clinical outcome after intra-arterial therapy for acute ischemic stroke.Q37178669
Good clinical outcome after ischemic stroke with successful revascularization is time-dependentQ37368356
Significance of large vessel intracranial occlusion causing acute ischemic stroke and TIA.Q37486129
Outcomes of mechanical endovascular therapy for acute ischemic stroke: a clinical registry study and systematic review.Q37858263
Pharmacokinetics of alteplase in the treatment of ischaemic strokeQ37976123
Spontaneous middle cerebral artery reperfusion in ischemic stroke. A follow-up study with transcranial DopplerQ39387643
Specific transcranial Doppler flow findings related to the presence and site of arterial occlusionQ39526109
Early recanalization after intravenous administration of recombinant tissue plasminogen activator as assessed by pre- and post-thrombolytic angiography in acute ischemic stroke patientsQ39775137
Predictors of good clinical outcomes, mortality, and successful revascularization in patients with acute ischemic stroke undergoing thrombectomy: pooled analysis of the Mechanical Embolus Removal in Cerebral Ischemia (MERCI) and Multi MERCI TrialsQ39934242
Evolving paradigms in neuroimaging of the ischemic penumbra.Q40477142
Comparison of intravenous alteplase with a combined intravenous-endovascular approach in patients with stroke and confirmed arterial occlusion (RECANALISE study): a prospective cohort study.Q43506227
Comparison of mechanical embolectomy and intraarterial thrombolysis in acute ischemic stroke within the MCA: MERCI and Multi MERCI compared to PROACT II.Q46075511
Emergency treatment of acute ischemic stroke: expanding the time windowQ46111613
Mechanical approaches combined with intra-arterial pharmacological therapy are associated with higher recanalization rates than either intervention alone in revascularization of acute carotid terminus occlusion.Q47952489
Combined intravenous and intra-arterial recanalization for acute ischemic stroke: the Interventional Management of Stroke StudyQ47961940
Hyperdense middle cerebral artery sign: can it be used to select intra-arterial versus intravenous thrombolysis in acute ischemic stroke?Q48100034
SYNTHESIS expansion: design of a nonprofit, pragmatic, randomized, controlled trial on the best fast-track endovascular treatment vs. standard intravenous alteplase for acute ischemic stroke.Q48264894
Site of arterial occlusion identified by transcranial Doppler predicts the response to intravenous thrombolysis for stroke.Q48278361
Intra-arterial or intravenous thrombolysis for acute ischemic stroke? The SYNTHESIS pilot trialQ48291623
IV vs. IA TPA in acute ischemic stroke with CT angiographic evidence of major vessel occlusion: a feasibility study.Q48709129
Results of a multicentre, randomised controlled trial of intra-arterial urokinase in the treatment of acute posterior circulation ischaemic strokeQ48877140
Guidelines for thrombolytic therapy for acute stroke: a supplement to the guidelines for the management of patients with acute ischemic stroke. A statement for healthcare professionals from a Special Writing Group of the Stroke Council, American HeaQ48936157
Tissue plasminogen activator reduces neurological damage after cerebral embolism.Q53986915
Effect of Intravenous Thrombolysis on MRI Parameters and Functional Outcome in Acute Stroke <6 HoursQ56971524
Low Rates of Acute Recanalization With Intravenous Recombinant Tissue Plasminogen Activator in Ischemic StrokeQ57756700
P6195funding schemegrantQ230788
P433issue5
P407language of work or nameEnglishQ1860
P921main subjecthealth careQ31207
mortality rateQ58702
thrombolysisQ1931577
P5008on focus list of Wikimedia projectWikimedia–NIOSH collaborationQ104416361
P304page(s)430-434
P12526performing organizationWest Virginia UniversityQ115376
P577publication date2012-07-28
P1433published inJournal of NeuroInterventional SurgeryQ6295638
P859sponsorNational Institute for Occupational Safety and HealthQ60346
P1476titleEndovascular therapy yields significantly superior outcomes for large vessel occlusions compared with intravenous thrombolysis: is it time to randomize?
P478volume5

Reverse relations

cites work (P2860)
Q45068832A population-based incidence of M2 strokes indicates potential expansion of large vessel occlusions amenable to endovascular therapy.
Q38722253Endovascular Treatment Versus Intravenous Thrombolysis for Acute Ischemic Stroke: a Quantitative Review and Meta-Analysis of 21 Randomized Trials
Q37518030Endovascular therapy in hyperacute ischaemic stroke: history and current status
Q44993430Hospital-based financial analysis of endovascular therapy and intravenous thrombolysis for large vessel acute ischemic strokes: the 'bottom line'.
Q44564922Intravenous thrombolysis of large vessel occlusions is associated with higher hospital costs than small vessel strokes: a rationale for developing stroke severity-based financial models
Q44998853Intravenous thrombolysis outcomes in patients presenting with large vessel acute ischemic strokes--CT angiography-based prognosis
Q39985382Sudden coma from acute bilateral m1 occlusion: successful treatment with mechanical thrombectomy
Q34498039Understanding IMS III: old data shed new light on a futile trial
Q37161839Unique cause of right hemispheric syndrome: Embolism of myocardium after open septal myectomy.