| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1015747323 |
| P356 | DOI | 10.1007/S00439-008-0593-6 |
| P3181 | OpenCitations bibliographic resource ID | 3952235 |
| P698 | PubMed publication ID | 19034520 |
| P5875 | ResearchGate publication ID | 23498334 |
| P50 | author | Mark Thomas | Q6767708 |
| P2093 | author name string | Yuval Itan | |
| Catherine J. E. Ingram | |||
| Charlotte A. Mulcare | |||
| Dallas M. Swallow | |||
| P2860 | cites work | Hydrogen breath testing versus LCT genotyping for the diagnosis of lactose intolerance: a matter of age? | Q80489655 |
| Lactase persistence/non-persistence variants, C/T_13910 and G/A_22018, as a diagnostic tool for lactose intolerance in IBS patients | Q80812645 | ||
| Gene-culture coevolution between cattle milk protein genes and human lactase genes | Q22122052 | ||
| Regulation of lactase-phlorizin hydrolase gene expression by the caudal-related homoeodomain protein Cdx-2 | Q24530103 | ||
| Interaction between the homeodomain proteins Cdx2 and HNF1alpha mediates expression of the lactase-phlorizin hydrolase gene | Q24531962 | ||
| Genetic signatures of strong recent positive selection at the lactase gene | Q24533797 | ||
| Regulation of intestinal lactase in adult hypolactasia | Q24564897 | ||
| Independent introduction of two lactase-persistence alleles into human populations reflects different history of adaptation to milk culture | Q24643704 | ||
| Convergent adaptation of human lactase persistence in Africa and Europe | Q24655819 | ||
| Evidence of still-ongoing convergence evolution of the lactase persistence T-13910 alleles in humans | Q24677659 | ||
| Darwin's illness revealed | Q24680178 | ||
| Systemic lactose intolerance: a new perspective on an old problem | Q24680204 | ||
| The International HapMap Project | Q27860695 | ||
| Lactose intolerance | Q28141485 | ||
| Lactase persistence DNA variant enhances lactase promoter activity in vitro: functional role as a cis regulatory element | Q28201340 | ||
| Identification of a variant associated with adult-type hypolactasia | Q28215372 | ||
| An upstream polymorphism associated with lactase persistence has increased enhancer activity | Q28238875 | ||
| Microsatellite variation and evolution of human lactase persistence | Q28253975 | ||
| Gata4 is essential for the maintenance of jejunal-ileal identities in the adult mouse small intestine | Q28510344 | ||
| Hepatocyte nuclear factor-1alpha is required for expression but dispensable for histone acetylation of the lactase-phlorizin hydrolase gene in vivo | Q28588655 | ||
| Gata4 and Hnf1alpha are partially required for the expression of specific intestinal genes during development | Q28590698 | ||
| Expression and intracellular transport of microvillus membrane hydrolases in human intestinal epithelial cells | Q28636987 | ||
| Absence of the lactase-persistence-associated allele in early Neolithic Europeans | Q29541806 | ||
| Positive natural selection in the human lineage | Q29614585 | ||
| Colonic adaptation to daily lactose feeding in lactose maldigesters reduces lactose intolerance | Q33485829 | ||
| Tolerance to the daily ingestion of two cups of milk by individuals claiming lactose intolerance | Q33486717 | ||
| The bioavailability of dietary calcium | Q33887942 | ||
| Differential activation of intestinal gene promoters: functional interactions between GATA-5 and HNF-1 alpha. | Q33951590 | ||
| Cow's milk allergy: a complex disorder | Q33992511 | ||
| Lactase haplotype diversity in the Old World | Q34043700 | ||
| The causal element for the lactase persistence/non-persistence polymorphism is located in a 1 Mb region of linkage disequilibrium in Europeans. | Q34221675 | ||
| ISOLATED INTESTINAL LACTASE DEFICIENCY IN THE ADULT | Q34255108 | ||
| Biogenesis of intestinal lactase-phlorizin hydrolase in adults with lactose intolerance. Evidence for reduced biosynthesis and slowed-down maturation in enterocytes | Q34262176 | ||
| The biosynthetic basis of adult lactase deficiency | Q34262202 | ||
| Lactase polymorphism in adult British natives: estimating allele frequencies by enzyme assays in autopsy samples. | Q34270370 | ||
| The T allele of a single-nucleotide polymorphism 13.9 kb upstream of the lactase gene (LCT) (C-13.9kbT) does not predict or cause the lactase-persistence phenotype in Africans | Q34315984 | ||
| Phylogenetic analysis of the evolution of lactose digestion in adults. | Q34439496 | ||
| Evaluation of a novel reverse-hybridization StripAssay for typing DNA variants useful in diagnosis of adult-type hypolactasia | Q34656054 | ||
| The T/G 13915 variant upstream of the lactase gene (LCT) is the founder allele of lactase persistence in an urban Saudi population | Q34697321 | ||
| A genetic test which can be used to diagnose adult-type hypolactasia in children | Q35596958 | ||
| Molecular basis of lactase levels in adult humans | Q35597595 | ||
| A stochastic model of gene-culture coevolution suggested by the "culture historical hypothesis" for the evolution of adult lactose absorption in humans | Q35602772 | ||
| Improved clinical tolerance to chronic lactose ingestion in subjects with lactose intolerance: a placebo effect? | Q35841232 | ||
| Impact of O-glycosylation on the function of human intestinal lactase-phlorizin hydrolase. Characterization of glycoforms varying in enzyme activity and localization of O-glycoside addition | Q38323589 | ||
| Beja and Nilotes: nomadic pastoralist groups in the Sudan with opposite distributions of the adult lactase phenotypes | Q38897841 | ||
| A novel polymorphism associated with lactose tolerance in Africa: multiple causes for lactase persistence? | Q39094353 | ||
| The acceptability of milk and milk products in populations with a high prevalence of lactose intolerance | Q39442364 | ||
| A comparison of calcium, vitamin D, or both for nutritional rickets in Nigerian children. | Q39519016 | ||
| The geographic hypothesis and lactose malabsorption. A weighing of the evidence | Q39779413 | ||
| Structure of the chromosomal gene and cDNAs coding for lactase-phlorizin hydrolase in humans with adult-type hypolactasia or persistence of lactase | Q40562629 | ||
| Control of lactase in human adult-type hypolactasia and in weaning rabbits and rats | Q40577384 | ||
| Gene-dosage effect on intestinal lactase activity demonstrated in vivo | Q40606625 | ||
| Clinical picture of hypolactasia and lactose intolerance. | Q40678465 | ||
| The prosequence of human lactase-phlorizin hydrolase modulates the folding of the mature enzyme | Q40761800 | ||
| Common polymorphism in a highly variable region upstream of the human lactase gene affects DNA-protein interactions | Q40916208 | ||
| Maturation of human intestinal lactase-phlorizin hydrolase: generation of the brush border form of the enzyme involves at least two proteolytic cleavage steps | Q41215458 | ||
| Transport, function, and sorting of lactase-phlorizin hydrolase in Madin-Darby canine kidney cells. | Q41493342 | ||
| Primary adult lactose intolerance and the milking habit: a problem in biologic and cultural interrelations. II. A culture historical hypothesis | Q41522317 | ||
| The homeodomain protein Cdx2 regulates lactase gene promoter activity during enterocyte differentiation | Q41710607 | ||
| Expression of lactase-phlorizin hydrolase in sheep is regulated at the RNA level | Q41952682 | ||
| DNA test for hypolactasia premature. | Q42844333 | ||
| Did malaria select for primary adult lactase deficiency? | Q43214167 | ||
| Lactose absorption in patients with ovarian cancer | Q44122855 | ||
| Lactose tolerance in adult Jordanian Arabs | Q44141813 | ||
| Milk, milk products and lactose intake and ovarian cancer risk: a meta-analysis of epidemiological studies | Q44403574 | ||
| Genetic predisposition for adult lactose intolerance and relation to diet, bone density, and bone fractures. | Q44749835 | ||
| Genetic variant of lactase-persistent C/T-13910 is associated with bone fractures in very old age. | Q45236104 | ||
| Evaluation of a new DNA test compared with the lactose hydrogen breath test for the diagnosis of lactase non-persistence | Q45270219 | ||
| GATA family transcription factors activate lactase gene promoter in intestinal Caco-2 cells | Q46559337 | ||
| Genetically defined adult-type hypolactasia and self-reported lactose intolerance as risk factors of osteoporosis in Finnish postmenopausal women | Q46598996 | ||
| T-13910 DNA variant associated with lactase persistence interacts with Oct-1 and stimulates lactase promoter activity in vitro | Q46814728 | ||
| Complex regulation of the lactase-phlorizin hydrolase promoter by GATA-4. | Q47392177 | ||
| Primary lactase deficiency and past malarial endemicity in Sardinia | Q47840216 | ||
| Coordinate expression of lactase-phlorizin hydrolase mRNA and enzyme levels in rat intestine during development | Q48269530 | ||
| Pitfalls in LightCycler diagnosis of the single-nucleotide polymorphism 13.9 kb upstream of the lactase gene that is associated with adult-type hypolactasia. | Q50951728 | ||
| The lactase persistence/non-persistence polymorphism is controlled by a cis-acting element. | Q52209390 | ||
| Lactase gene promoter fragments mediate differential spatial and temporal expression patterns in transgenic mice. | Q53626444 | ||
| Lactose nutrition and natural selection. | Q54020788 | ||
| A novel proximal -13914G>A base replacement in the vicinity of the common-13910T/C lactase gene variation results in an atypical LightCycler melting curve in testing with the MutaREAL Lactase test. | Q54564339 | ||
| High intestinal lactase concentrations in adult Arbs in Saudi Arabia. | Q55035521 | ||
| The genetic variant of lactase persistence C (−13910) T as a risk factor for type I and II diabetes in the Finnish population | Q57365874 | ||
| High prevalence of lactose absorbers in Northern Sardinian patients with type 1 and type 2 diabetes mellitus | Q57560625 | ||
| Regulation of Intestine-specific Spatiotemporal Expression by the Rat Lactase Promoter | Q60285343 | ||
| Prospective Comparison of Indirect Methods for Detecting Lactase Deficiency | Q67328848 | ||
| Mosaic pattern of lactase expression by villous enterocytes in human adult-type hypolactasia | Q67677630 | ||
| The inheritance of selective adult-type lactose malabsorption | Q69065595 | ||
| Genetic aetiology of lactose intolerance | Q70074018 | ||
| A study of lactose absorption capacity in twins | Q70493933 | ||
| Distribution of the lactase phenotypes in the population of the Democratic Republic of the Sudan | Q71558058 | ||
| Folding of human intestinal lactase-phlorizin hydrolase | Q71942241 | ||
| Mosaic regulation of lactase in human adult-type hypolactasia | Q72036093 | ||
| DNA polymorphisms in the lactase gene. Linkage disequilibrium across the 70-kb region | Q72280171 | ||
| 1 kb of the lactase-phlorizin hydrolase promoter directs post-weaning decline and small intestinal-specific expression in transgenic mice | Q72345443 | ||
| Fecal hydrogen production and consumption measurements. Response to daily lactose ingestion by lactose maldigesters | Q73114694 | ||
| Lactose intolerance-a confusing clinical diagnosis | Q73386503 | ||
| Transcriptional regulation of pig lactase-phlorizin hydrolase: involvement of HNF-1 and FREACs | Q74637105 | ||
| INTESTINAL LACTASE DEFICIENCY AND LACTOSE INTOLERANCE IN ADULTS. PRELIMINARY REPORT | Q76581504 | ||
| Lactase haplotype frequencies in Caucasians: association with the lactase persistence/non-persistence polymorphism | Q77515786 | ||
| A randomized trial of Lactobacillus acidophilus BG2FO4 to treat lactose intolerance | Q77926288 | ||
| P433 | issue | 6 | |
| P304 | page(s) | 579-591 | |
| P577 | publication date | 2008-11-26 | |
| P1433 | published in | Human Genetics | Q5937167 |
| P1476 | title | Lactose digestion and the evolutionary genetics of lactase persistence | |
| P478 | volume | 124 |
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| Q53096015 | Comparing the rehydration potential of different milk-based drinks to a carbohydrate-electrolyte beverage. |
| Q28306390 | Comparison of lactase persistence polymorphism in ancient and present-day Hungarian populations |
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| Q48260115 | Functional characterization of adaptive variation within a cis-regulatory element influencing Drosophila melanogaster growth. |
| Q35020667 | Functional significance of single nucleotide polymorphisms in the lactase gene in diverse US patients and evidence for a novel lactase persistence allele at -13909 in those of European ancestry |
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