Dose- and time-dependent epigenetic changes in the livers of Fisher 344 rats exposed to furan

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Dose- and time-dependent epigenetic changes in the livers of Fisher 344 rats exposed to furan is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/TOXSCI/KFU044
P932PMC publication ID4064012
P698PubMed publication ID24614236
P5875ResearchGate publication ID260682728

P50authorVolodymyr TryndyakQ55446237
Tetyana KobetsQ59995330
Aline de ContiQ114387910
Daniel R DoergeQ114387911
Frederick A. BelandQ42700100
P2093author name stringBeverly Montgomery
Claudia Escudero-Lourdes
Igor Petrovych Pogribny
P2860cites workFuran-induced dose-response relationships for liver cytotoxicity, cell proliferation, and tumorigenicity (furan-induced liver tumorigenicity).Q43488609
Chronic inorganic arsenic exposure induces hepatic global and individual gene hypomethylation: implications for arsenic hepatocarcinogenesisQ44836543
ACB-PCR measurement of spontaneous and furan-induced H-ras codon 61 CAA to CTA and CAA to AAA mutation in B6C3F1 mouse liverQ44944754
Aberrant CpG island hypermethylation in dysplastic nodules and early HCC of hepatitis B virus-related human multistep hepatocarcinogenesisQ45370630
VOC and particulate emissions from commercial cigarettes: analysis of 2,5-DMF as an ETS tracerQ46693647
Survey of furan in heat processed foods by headspace gas chromatography/mass spectrometry and estimated adult exposureQ46724917
The epigenetic magic of histone lysine methylationQ48591117
Genotoxicity of furan in Big Blue ratsQ50261983
NTP Toxicology and Carcinogenesis Studies of Furfural (CAS No. 98-01-1) in F344/N Rats and B6C3F1 Mice (Gavage Studies)Q50465739
FuranQ73209958
Frequency of Ha-ras-1 gene mutations inversely correlated with furan dose in mouse liver tumorsQ73321528
Furan is not genotoxic in the micronucleus assay in vivo or in vitroQ79561635
Epigenetics and environmental chemicalsQ24629035
Role of epigenetic aberrations in the development and progression of human hepatocellular carcinomaQ27023524
The epigenomics of cancerQ28289975
Toxicity and carcinogenicity of furan in human dietQ34104469
Identification of Driver and Passenger DNA Methylation in Cancer by Epigenomic AnalysisQ34181789
Furan in heat-treated foods: formation, exposure, toxicity, and aspects of risk assessmentQ34277773
Low doses of the carcinogen furan alter cell cycle and apoptosis gene expression in rat liver independent of DNA methylationQ34282873
Altered DNA methylation: a secondary mechanism involved in carcinogenesisQ34504084
Dnmt3a protects active chromosome domains against cancer-associated hypomethylationQ34531301
Epigenetic theories of cancer initiationQ34544420
The epigenetics of cancer etiologyQ35920461
Epigenetic regulation of condensin-mediated genome organization during the cell cycle and upon DNA damage through histone H3 lysine 56 acetylationQ36442657
Electrophilic intermediates produced by bioactivation of furanQ36673570
Towards incorporating epigenetic mechanisms into carcinogen identification and evaluationQ37151661
The RASSF proteins in cancer; from epigenetic silencing to functional characterizationQ37432498
Global DNA methylation in a population with aflatoxin B1 exposureQ37445245
Furan carcinogenicity: DNA binding and genotoxicity of furan in rats in vivo.Q37480300
Genome-wide methylation analysis and epigenetic unmasking identify tumor suppressor genes in hepatocellular carcinoma.Q37481324
DNA methylome alterations in chemical carcinogenesisQ38046356
Case study on the utility of hepatic global gene expression profiling in the risk assessment of the carcinogen furanQ38483926
Tests for genotoxicity and mutagenicity of furan and its metabolite cis-2-butene-1,4-dial in L5178Y tk+/- mouse lymphoma cellsQ39937913
Inactivation of Dnmt3b in mouse embryonic fibroblasts results in DNA hypomethylation, chromosomal instability, and spontaneous immortalization.Q40448471
High frequency of promoter hypermethylation of RASSF1A and p16 and its relationship to aflatoxin B1-DNA adduct levels in human hepatocellular carcinomaQ40701324
Differential expression of long noncoding RNAs in the livers of female B6C3F1 mice exposed to the carcinogen furan.Q42710254
Gene expression and epigenetic changes by furan in rat liverQ42723894
Toxic and genotoxic effects of oral administration of furan in mouse liver.Q43145669
Evidence of oxidative stress and associated DNA damage, increased proliferative drive, and altered gene expression in rat liver produced by the cholangiocarcinogenic agent furanQ43177447
P4510describes a project that usesImageQuantQ112270642
P433issue2
P304page(s)371-380
P577publication date2014-03-10
P1433published inToxicological SciencesQ2446966
P1476titleDose- and time-dependent epigenetic changes in the livers of Fisher 344 rats exposed to furan
P478volume139

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cites work (P2860)
Q34389874Analysis of Statistical Methods Currently used in Toxicology Journals.
Q26769972DNA Methylation Analysis: Choosing the Right Method
Q52690380Effects of continuous bisphenol A exposure from early gestation on 90 day old rat testes function and sperm molecular profiles: A CLARITY-BPA consortium study.
Q41658103From the Cover: Sperm Molecular Biomarkers Are Sensitive Indicators of Testicular Injury following Subchronic Model Toxicant Exposure
Q39166819Low dose assessment of the carcinogenicity of furan in male F344/N Nctr rats in a 2-year gavage study.
Q38244618Noncoding RNA response to xenobiotic exposure: an indicator of toxicity and carcinogenicity
Q35214589Persistence of furan-induced epigenetic aberrations in the livers of F344 rats.
Q47160723Risks for public health related to the presence of furan and methylfurans in food
Q28833760Toxicogenomic assessment of liver responses following subchronic exposure to furan in Fischer F344 rats

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