Protective efficacy of the recombinant, live-attenuated, CYD tetravalent dengue vaccine in Thai schoolchildren: a randomised, controlled phase 2b trial

scientific article (publication date: 3 November 2012)

Protective efficacy of the recombinant, live-attenuated, CYD tetravalent dengue vaccine in Thai schoolchildren: a randomised, controlled phase 2b trial is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0140-6736(12)61428-7
P3181OpenCitations bibliographic resource ID357113
P698PubMed publication ID22975340
P5875ResearchGate publication ID230848750

P2093author name stringLang J
Wallace D
Chanthavanich P
Sabchareon A
Pengsaa K
Sirivichayakul C
Tornieporth NG
Viviani S
Suvannadabba S
Bouckenooghe A
Limkittikul K
Saville M
Dulyachai W
Jiwariyavej V
Moureau A
Wartel TA
P2860cites workDengueQ24570132
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Population dynamics of DENV-1 genotype V in Brazil is characterized by co-circulation and strain/lineage replacementQ40281096
Live-attenuated Tetravalent Dengue Vaccine in Dengue-naïve Children, Adolescents, and Adults in Mexico City: Randomized Controlled Phase 1 Trial of Safety and ImmunogenicityQ40344756
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The use of dengue nonstructural protein 1 antigen for the early diagnosis during the febrile stage in patients with dengue infectionQ40430989
The economic burden of dengueQ43151069
P433issue9853
P407language of work or nameEnglishQ1860
P921main subjectThailandQ869
vaccineQ134808
Dengue virusQ476209
attenuated vaccineQ1810913
P5008on focus list of Wikimedia projectScienceSourceQ55439927
P304page(s)1559-67
P577publication date2012-11-03
P1433published inThe LancetQ939416
P1476titleProtective efficacy of the recombinant, live-attenuated, CYD tetravalent dengue vaccine in Thai schoolchildren: a randomised, controlled phase 2b trial
P478volume380

Reverse relations

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Q36307457Live virus vaccines based on a yellow fever vaccine backbone: standardized template with key considerations for a risk/benefit assessment
Q37706823Long-term safety assessment of live attenuated tetravalent dengue vaccines: deliberations from a WHO technical consultation
Q40142974Lot-to-lot consistency of a tetravalent dengue vaccine in healthy adults in Australia: a randomised study.
Q37130999Low antibody titers 5 years after vaccination with the CYD-TDV dengue vaccine in both pre-immune and naïve vaccinees
Q39084398Lyso-myristoyl phosphatidylcholine micelles sustain the activity of Dengue non-structural (NS) protein 3 protease domain fused with the full-length NS2B.
Q38945522Machine learning methods enable predictive modeling of antibody feature:function relationships in RV144 vaccinees
Q35065031Male mosquitoes as vehicles for insecticide
Q35488254Mapping the Interactions between the NS4B and NS3 proteins of dengue virus
Q23032973Mechanism and significance of cell type-dependent neutralization of flaviviruses
Q57812953Memory T Cells in Flavivirus Vaccination
Q40530597Modeling the Role of Epitope Arrangement on Antibody Binding Stoichiometry in Flaviviruses
Q35326145Modeling the impact on virus transmission of Wolbachia-mediated blocking of dengue virus infection of Aedes aegypti
Q40243226Modelling interventions during a dengue outbreak
Q35856554Modelling the immunological response to a tetravalent dengue vaccine from multiple phase-2 trials in Latin America and South East Asia
Q38120526Multiantibody strategies for HIV.
Q28296618Neurological complications of dengue virus infection
Q89453187Neutralizing Antibody Correlates Analysis of Tetravalent Dengue Vaccine Efficacy Trials in Asia and Latin America
Q36498207Neutralizing antibody titers against dengue virus correlate with protection from symptomatic infection in a longitudinal cohort
Q35058877Neutralizing dengue antibody in pregnant Thai women and cord blood
Q35218614New challenges in modern vaccinology
Q38646923New insights into the immunopathology and control of dengue virus infection
Q38596321Next generation dengue vaccines: A review of the preclinical development pipeline
Q28656158No effect of insecticide treated curtain deployment on aedes infestation in a cluster randomized trial in a setting of low dengue transmission in Guantanamo, Cuba
Q38904898Novel vaccination approach for dengue infection based on recombinant immune complex universal platform
Q36816140Novel vaccine strategies against emerging viruses
Q36895813Original antigenic sin in dengue revisited
Q58805757Oviposition Deterrent Efficacy and Characteristics of a Botanical Natural Product, (L.) Oil-Alginate Beads, against (L.)
Q38636217Paradoxical role of antibodies in dengue virus infections: considerations for prophylactic vaccine development
Q28729784Patterns of cellular immunity associated with experimental infection with rDEN2Δ30 (Tonga/74) supports its suitability as a human DENV challenge strain
Q37694849Persistence of Th1/Tc1 responses one year after tetravalent dengue vaccination in adults and adolescents in Singapore
Q33773563Phase 1 Randomized Study of a Tetravalent Dengue Purified Inactivated Vaccine in Healthy Adults in the United States
Q91704346Phenotype and functionality of follicular helper T cells in patients with acute dengue infection
Q34746139Pichia pastoris-expressed dengue 2 envelope forms virus-like particles without pre-membrane protein and induces high titer neutralizing antibodies
Q40136145Pichia pastoris-expressed dengue 3 envelope-based virus-like particles elicit predominantly domain III-focused high titer neutralizing antibodies.
Q37683785Plaque reduction neutralization antibody test does not accurately predict protection against dengue infection in Ratchaburi cohort, Thailand
Q38664198Points for Consideration for dengue vaccine introduction - recommendations by the Dengue Vaccine Initiative
Q26247399Potent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance Profiling
Q40040450Potent Plasmablast-Derived Antibodies Elicited by the National Institutes of Health Dengue Vaccine
Q34080726Potential opportunities and perils of imperfect dengue vaccines.
Q37666763Preclinical and clinical development of a YFV 17 D-based chimeric vaccine against West Nile virus
Q40148624Preclinical development of a dengue tetravalent recombinant subunit vaccine: Immunogenicity and protective efficacy in nonhuman primates
Q59209121Predatory efficiency of the copepod Megacyclops formosanus and toxic effect of the red alga Gracilaria firma-synthesized silver nanoparticles against the dengue vector Aedes aegypti
Q35221318Preexisting neutralizing antibody responses distinguish clinically inapparent and apparent dengue virus infections in a Sri Lankan pediatric cohort
Q38202176Preparing for dengue vaccine introduction in ASEAN countries: recommendations from the first ADVA regional workshop
Q21562244Preparing for dengue vaccine introduction: recommendations from the 1st dengue v2V International Meeting
Q38368332Prevention and Control Strategies to Counter Dengue Virus Infection
Q28729782Prevention and control of dengue-the light at the end of the tunnel
Q38871575Production of a Recombinant Dengue Virus 2 NS5 Protein and Potential Use as a Vaccine Antigen
Q38794583Progress towards understanding the pathogenesis of dengue hemorrhagic fever.
Q35836631Prospective cohort study with active surveillance for fever in four dengue endemic countries in Latin America
Q30235612Prospects for a Zika Virus Vaccine
Q40191440Prospects for a dengue vaccine: progress and pitfalls.
Q35898318Protection against dengue disease by synthetic nucleic acid antibody prophylaxis/immunotherapy
Q33414156Protection against dengue virus infection in mice by administration of antibodies against modified nonstructural protein 1.
Q38731663Protective and immunological behavior of chimeric yellow fever dengue vaccine
Q40166759Protective immune responses to dengue virus infection and vaccines: perspectives from the field to the bench
Q34999848Public acceptance and willingness-to-pay for a future dengue vaccine: a community-based survey in Bandung, Indonesia
Q34351411QTL mapping of genome regions controlling temephos resistance in larvae of the mosquito Aedes aegypti
Q38266413RNA-based viral vectors
Q25202252Rapid and Non-destructive Detection and Identification of Two Strains of Wolbachia in Aedes aegypti by Near-Infrared Spectroscopy
Q27334248Rational design of a live attenuated dengue vaccine: 2'-o-methyltransferase mutants are highly attenuated and immunogenic in mice and macaques
Q26825426Recent Advances in Dengue: Relevance to Puerto Rico
Q38605203Recent advances in dengue pathogenesis and clinical management
Q92859173Recent advances in understanding dengue
Q38303232Recent progress in dengue vaccine development
Q51782806Recombinant Zika virus envelope protein elicited protective immunity against Zika virus in immunocompetent mice.
Q39028302Recombinant lipidated dengue-4 envelope protein domain III elicits protective immunity
Q47681827Redefining priorities towards graded travel-related infectious disease research
Q36799290Redesign of a cross-reactive antibody to dengue virus with broad-spectrum activity and increased in vivo potency
Q37109553Reduced risk of disease during postsecondary dengue virus infections
Q58759739Refined efficacy estimates of the Sanofi Pasteur dengue vaccine CYD-TDV using machine learning
Q40185164Refolding of a fully functional flavivirus methyltransferase revealed that S-adenosyl methionine but not S-adenosyl homocysteine is copurified with flavivirus methyltransferase
Q38974932Repurposing of prochlorperazine for use against dengue virus infection
Q26825672Reviewing dengue: still a neglected tropical disease?
Q38174301Revisiting dengue virus-host cell interaction: new insights into molecular and cellular virology
Q92689689Revisiting the Correlate of Reduced HIV Infection Risk in the Rv144 Vaccine Trial
Q35034240Role of humoral versus cellular responses induced by a protective dengue vaccine candidate
Q26700096Safety Overview of a Recombinant Live-Attenuated Tetravalent Dengue Vaccine: Pooled Analysis of Data from 18 Clinical Trials
Q36024479Safety and Immunogenicity of a Live Attenuated Tetravalent Dengue Vaccine Candidate in Flavivirus-Naive Adults: A Randomized, Double-Blinded Phase 1 Clinical Trial
Q49833104Safety and Immunogenicity of a Tetravalent Dengue DNA Vaccine Administered with a Cationic Lipid-Based Adjuvant in a Phase 1 Clinical Trial
Q39468688Safety and Immunogenicity of a Tetravalent Dengue Vaccine Candidate in Healthy Children and Adults in Dengue-Endemic Regions: A Randomized, Placebo-Controlled Phase 2 Study
Q36288109Safety and immunogenicity of a recombinant live attenuated tetravalent dengue vaccine (DENVax) in flavivirus-naive healthy adults in Colombia: a randomised, placebo-controlled, phase 1 study
Q40231133Safety and immunogenicity of a tetravalent dengue vaccine in healthy children aged 2-11 years in Malaysia: a randomized, placebo-controlled, Phase III study
Q40235135Safety and immunogenicity of three tetravalent dengue vaccine formulations in healthy adults in the USA.
Q52684747Safety issues from a Phase 3 clinical trial of a live-attenuated chimeric yellow fever tetravalent dengue vaccine.
Q38232097Safety, immunogenicity and efficacy of a recombinant tetravalent dengue vaccine: a meta-analysis of randomized trials.
Q90733120Seeking Flavivirus Cross-Protective Immunity
Q35250382Sensitivity and specificity of a novel classifier for the early diagnosis of dengue
Q98164941Sequential immunization induces strong and broad immunity against all four dengue virus serotypes
Q34496118Seroprevalence of neutralizing antibodies against dengue virus in two localities in the state of Morelos, Mexico
Q37553822Silencing sexually transmitted infections: topical siRNA-based interventions for the prevention of HIV and HSV
Q33709817Simulations to compare efficacies of tetravalent dengue vaccines and mosquito vector control
Q35557524Site-specific characterization of envelope protein N-glycosylation on Sanofi Pasteur's tetravalent CYD dengue vaccine.
Q61053717Small molecules targeting the flavivirus E protein with broad-spectrum activity and antiviral efficacy in vivo
Q37677793Socially structured human movement shapes dengue transmission despite the diffusive effect of mosquito dispersal
Q36332097Socioeconomic and environmental determinants of dengue transmission in an urban setting: An ecological study in Nouméa, New Caledonia
Q28656178Spatiotemporal distribution of dengue vectors & identification of high risk zones in district Sonitpur, Assam, India
Q38773323Status of vaccine research and development of vaccines for dengue
Q104617064Stimulation of B Cell Immunity in Flavivirus-Naive Individuals by the Tetravalent Live Attenuated Dengue Vaccine TV003
Q24740325Structural basis of potent Zika–dengue virus antibody cross-neutralization
Q26700120Structure-Guided Design of an Anti-dengue Antibody Directed to a Non-immunodominant Epitope
Q40205459Stumbles on the path to dengue control
Q56355933Successful Vaccines
Q35077611Synthetic 1,4-pyran naphthoquinones are potent inhibitors of dengue virus replication
Q92909202Systematic review of dengue vaccine efficacy
Q26782580Systems Biology Approach for Cancer Vaccine Development and Evaluation
Q66679253T Cell Responses Induced by DNA Vaccines Based on the DENV2 E and NS1 Proteins in Mice: Importance in Protection and Immunodominant Epitope Identification
Q38631171T cell immunity to dengue virus and implications for vaccine design.
Q33414009T-cell immunity to infection with dengue virus in humans
Q24288867Tackling dengue fever: Current status and challenges
Q38923188Tetravalent Dengue Vaccine: A Review in the Prevention of Dengue Disease
Q40170464Tetravalent dengue DIIIC protein together with alum and ODN elicits a Th1 response and neutralizing antibodies in mice
Q26700056The Cellular Bases of Antibody Responses during Dengue Virus Infection
Q26995782The Complexity of a Dengue Vaccine: A Review of the Human Antibody Response
Q92756077The Dengue ED3 Dot Assay, a Novel Serological Test for the Detection of Denguevirus Type-Specific Antibodies and Its Application in a Retrospective Seroprevalence Study
Q54557957The Dengue Virus Replication Complex: From RNA Replication to Protein-Protein Interactions to Evasion of Innate Immunity.
Q59360089The Development of Peptide-based Antimicrobial Agents against Dengue Virus
Q36776077The Effect of Temperature on Wolbachia-Mediated Dengue Virus Blocking in Aedes aegypti
Q28954848The RNAi pathway plays a small part in Wolbachia-mediated blocking of dengue virus in mosquito cells
Q27332223The Spread of Dengue in an Endemic Urban Milieu--The Case of Delhi, India
Q55432397The US Military Commitment to Vaccine Development: A Century of Successes and Challenges.
Q47558217The bright and the dark side of human antibody responses to flaviviruses: lessons for vaccine design.
Q33624593The contribution of vaccination to global health: past, present and future
Q42987133The dengue human challenge model: has the time come to accept this challenge?
Q26314683The dengue vaccine pipeline: Implications for the future of dengue control
Q35034544The effects of vector movement and distribution in a mathematical model of dengue transmission
Q24628768The global distribution and burden of dengue
Q34989348The high-affinity human IgG receptor Fc gamma receptor I (FcγRI) is not associated with vascular leakage of dengue
Q34992520The human CD8+ T cell responses induced by a live attenuated tetravalent dengue vaccine are directed against highly conserved epitopes
Q40205673The human dengue challenge experience at the Walter Reed Army Institute of Research
Q58569778The immune response against flaviviruses
Q38176451The introduction of new vaccines into developing countries. V: Will we lose a decade or more in the introduction of dengue vaccines to developing countries?
Q40109446The live attenuated dengue vaccine TV003 elicits complete protection against dengue in a human challenge model
Q38994574The mechanistic role of antibodies to dengue virus in protection and disease pathogenesis
Q35236379The protein DIIIC-2, aggregated with a specific oligodeoxynucleotide and adjuvanted in alum, protects mice and monkeys against DENV-2.
Q38284671The relevance of dengue virus genotypes surveillance at country level before vaccine approval
Q33676847The role of the mosquito in a dengue human infection model
Q37135489The successful induction of T-cell and antibody responses by a recombinant measles virus-vectored tetravalent dengue vaccine provides partial protection against dengue-2 infection.
Q34614953The synergistic effect of combined immunization with a DNA vaccine and chimeric yellow fever/dengue virus leads to strong protection against dengue
Q35069160The type-specific neutralizing antibody response elicited by a dengue vaccine candidate is focused on two amino acids of the envelope protein
Q26865102The yellow fever 17D virus as a platform for new live attenuated vaccines
Q38149195Therapeutic antibodies as a treatment option for dengue fever
Q34607919Therapeutic efficacy of antibodies lacking Fcγ receptor binding against lethal dengue virus infection is due to neutralizing potency and blocking of enhancing antibodies [corrected].
Q37230310Three-Month Real-Time Dengue Forecast Models: An Early Warning System for Outbreak Alerts and Policy Decision Support in Singapore
Q33854218Time-varying, serotype-specific force of infection of dengue virus
Q91173745Tracking the polyclonal neutralizing antibody response to a dengue virus serotype 1 type-specific epitope across two populations in Asia and the Americas
Q35097106Transmission-blocking antibodies against mosquito C-type lectins for dengue prevention
Q45323668Transplantation of a quaternary structure neutralizing antibody epitope from dengue virus serotype 3 into serotype 4.
Q28074355Trends in clinical trials of dengue vaccine
Q38540058Trials and tribulations on the path to developing a dengue vaccine
Q91741475Two Is Better Than One: Evidence for T-Cell Cross-Protection Between Dengue and Zika and Implications on Vaccine Design
Q33744074Type I interferon signals in macrophages and dendritic cells control dengue virus infection: implications for a new mouse model to test dengue vaccines
Q27011587Understanding the dengue viruses and progress towards their control
Q38126179Urbanization and geographic expansion of zoonotic arboviral diseases: mechanisms and potential strategies for prevention
Q40053434Use of a Recombinant Gamma-2 Herpesvirus Vaccine Vector against Dengue Virus in Rhesus Monkeys
Q59354478Using a virion assembly-defective dengue virus as a vaccine approach
Q34238916Utility, limitations, and future of non-human primates for dengue research and vaccine development
Q37184768Vaccination of volunteers with low-dose, live-attenuated, dengue viruses leads to serotype-specific immunologic and virologic profiles
Q40197584Vaccination strategies for SIR vector-transmitted diseases.
Q27014663Vaccine-mediated immunity against dengue and the potential for long-term protection against disease
Q28077521Vaccines and immunization strategies for dengue prevention
Q27007529Vaccines for the 21st century
Q37096221Vaccines for viral hemorrhagic fevers--progress and shortcomings
Q39172722Vaccines licensed and in clinical trials for the prevention of dengue
Q35195545Variability in dengue titer estimates from plaque reduction neutralization tests poses a challenge to epidemiological studies and vaccine development
Q33413903Vascular events in viral hemorrhagic fevers: a comparative study of dengue and hantaviruses
Q40261818Vector biology prospects in dengue research
Q58367215Viral genetic diversity and protective efficacy of a tetravalent dengue vaccine in two phase 3 trials
Q36082908Viral kinetics of primary dengue virus infection in non-human primates: a systematic review and individual pooled analysis
Q34262245Virus-like particle secretion and genotype-dependent immunogenicity of dengue virus serotype 2 DNA vaccine
Q36365735Viruses acquired abroad: what does the primary care physician need to know?
Q47232816Vivo-morpholino oligomers strongly inhibit dengue virus replication and production.
Q92538927Wanted Dead or Alive: A Correlate of Protection Against Dengue Virus
Q38674884Which Dengue Vaccine Approach Is the Most Promising, and Should We Be Concerned about Enhanced Disease after Vaccination? Questions Raised by the Development and Implementation of Dengue Vaccines: Example of the Sanofi Pasteur Tetravalent Dengue Vac
Q38157725Which Dengue Vaccine Approach Is the Most Promising, and Should We Be Concerned about Enhanced Disease after Vaccination? The Challenges of a Dengue Vaccine
Q40047872Which Dengue Vaccine Approach Is the Most Promising, and Should We Be Concerned about Enhanced Disease after Vaccination? There Is Only One True Winner
Q40245518Will people change their vector-control practices in the presence of an imperfect dengue vaccine?
Q35675701Wolbachia Reduces the Transmission Potential of Dengue-Infected Aedes aegypti
Q39008654Wolbachia: The selfish Trojan Horse in dengue control
Q26261644Zika virus disease: a current review of the literature

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