| scholarly article | Q13442814 |
| review article | Q7318358 |
| P50 | author | Jürg Tschopp | Q28320791 |
| P2093 | author name string | Martinon F | |
| Mayor A | |||
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | inflammasome complex | Q412405 |
| P304 | page(s) | 229-65 | |
| P577 | publication date | 2009-01-01 | |
| P1433 | published in | Annual Review of Immunology | Q567362 |
| P1476 | title | The inflammasomes: guardians of the body | |
| P478 | volume | 27 |
| Q35050189 | 3,4-methylenedioxy-β-nitrostyrene inhibits NLRP3 inflammasome activation by blocking assembly of the inflammasome |
| Q33718494 | 3-Hydroxyl-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor (statin)-induced 28-kDa interleukin-1β interferes with mature IL-1β signaling |
| Q37770954 | A 'complexity' of urate transporters |
| Q37557862 | A Double-edged Sword: Uric Acid and Neurological Disorders |
| Q42317064 | A Novel Role for Brain Natriuretic Peptide: Inhibition of IL-1β Secretion via Downregulation of NF-kB/Erk 1/2 and NALP3/ASC/Caspase-1 Activation in Human THP-1 Monocyte. |
| Q64950592 | A Novel Sex-Dependent Target for the Treatment of Postoperative Pain: The NLRP3 Inflammasome. |
| Q33906693 | A Yersinia effector protein promotes virulence by preventing inflammasome recognition of the type III secretion system |
| Q33886139 | A Yersinia effector with enhanced inhibitory activity on the NF-κB pathway activates the NLRP3/ASC/caspase-1 inflammasome in macrophages |
| Q22001534 | A bacterial E3 ubiquitin ligase IpaH9.8 targets NEMO/IKKgamma to dampen the host NF-kappaB-mediated inflammatory response |
| Q34315760 | A bioluminescent transposon reporter-trap identifies tumor-specific microenvironment-induced promoters in Salmonella for conditional bacterial-based tumor therapy |
| Q42183571 | A comparative study of stress-mediated immunological functions with the adjuvanticity of alum |
| Q38242025 | A long-awaited merger of the pathways mediating host defence and programmed cell death. |
| Q39003335 | A motive for killing: effector functions of regulated lytic cell death. |
| Q34758768 | A multicentre, randomised, double-blind, placebo-controlled trial with the interleukin-1 receptor antagonist anakinra in patients with systemic-onset juvenile idiopathic arthritis (ANAJIS trial) |
| Q37769443 | A new role for T cells in dampening innate inflammatory responses |
| Q36161438 | A novel role for APOBEC3: susceptibility to sexual transmission of murine acquired immunodeficiency virus (mAIDS) is aggravated in APOBEC3 deficient mice. |
| Q35621585 | A protective role for inflammasome activation following injury. |
| Q89180784 | A proximity-dependent biotinylation (BioID) approach flags the p62/sequestosome-1 protein as a caspase-1 substrate |
| Q27002620 | A review of hypothalamic-pituitary-adrenal axis function in chronic fatigue syndrome |
| Q24630474 | A role for the human nucleotide-binding domain, leucine-rich repeat-containing family member NLRC5 in antiviral responses |
| Q38773387 | A systematic approach to autoinflammatory syndromes: a spelling booklet for the beginner |
| Q36546351 | A virological view of innate immune recognition |
| Q34996919 | A20 restricts ubiquitination of pro-interleukin-1β protein complexes and suppresses NLRP3 inflammasome activity |
| Q38842848 | AIM2 inflammasome is associated with disease severity in tegumentary leishmaniasis caused by Leishmania (V.) braziliensis. |
| Q84078597 | AIMing 2 defend against intracellular pathogens |
| Q37856788 | AMP-activated protein kinase inhibits NF-κB signaling and inflammation: impact on healthspan and lifespan |
| Q36515084 | ATP release and purinergic signaling in NLRP3 inflammasome activation |
| Q51493013 | ATP-induced IL-1β secretion is selectively impaired in microglia as compared to hematopoietic macrophages. |
| Q35123281 | ATP-sensitive potassium channel (K(ATP))-dependent regulation of cardiotropic viral infections |
| Q35394987 | Accurate and simple measurement of the pro-inflammatory cytokine IL-1β using a whole blood stimulation assay |
| Q37474645 | Actin is an evolutionarily-conserved damage-associated molecular pattern that signals tissue injury in Drosophila melanogaster |
| Q37708784 | Activation of NLRP1 and NLRP3 inflammasomes contributed to cyclic stretch-induced pyroptosis and release of IL-1β in human periodontal ligament cells |
| Q37548150 | Activation of NLRP3 and AIM2 inflammasomes by Porphyromonas gingivalis infection |
| Q48295279 | Activation of NLRP3 inflammasome by cholesterol crystals in alcohol consumption induces atherosclerotic lesions. |
| Q43083568 | Activation of NLRP3 inflammasome complex potentiates venous thrombosis in response to hypoxia. |
| Q39320142 | Activation of NLRP3 inflammasome in alveolar macrophages contributes to mechanical stretch-induced lung inflammation and injury |
| Q37521297 | Activation of Nlrp3 inflammasomes enhances macrophage lipid-deposition and migration: implication of a novel role of inflammasome in atherogenesis |
| Q21134608 | Activation of P2X(7) receptor by ATP plays an important role in regulating inflammatory responses during acute viral infection |
| Q52930876 | Activation of inflammasomes in dendritic cells and macrophages by Mycoplasma salivarium. |
| Q34103835 | Activation of macrophages by P2X7-induced microvesicles from myeloid cells is mediated by phospholipids and is partially dependent on TLR4. |
| Q40549518 | Activation of nucleotide-binding domain-like receptor containing protein 3 inflammasome in dendritic cells and macrophages by Streptococcus sanguinis. |
| Q27334659 | Activation of the NLRP3 inflammasome by IAV virulence protein PB1-F2 contributes to severe pathophysiology and disease |
| Q34421170 | Activation of the NLRP3 inflammasome by intracellular poly I:C |
| Q34749353 | Activation of the NLRP3 inflammasome by vault nanoparticles expressing a chlamydial epitope. |
| Q35528594 | Activation of the NLRP3 inflammasome in association with calcium oxalate crystal induced reactive oxygen species in kidneys |
| Q35551778 | Activation of the Nlrp3 inflammasome by mitochondrial reactive oxygen species: a novel mechanism of albumin-induced tubulointerstitial inflammation |
| Q57258422 | Activation of the inflammasome by amorphous silica and TiO2nanoparticles in murine dendritic cells |
| Q30527774 | Activation of the pyrin inflammasome by intracellular Burkholderia cenocepacia |
| Q46095596 | Acute-on-chronic liver failure in cirrhosis. |
| Q37968304 | Adapting to environmental stresses: the role of the microbiota in controlling innate immunity and behavioral responses |
| Q91680550 | Adenosine Triphosphate Release is Required for Toll-Like Receptor-Induced Monocyte/Macrophage Activation, Inflammasome Signaling, Interleukin-1β Production, and the Host Immune Response to Infection |
| Q37492552 | Adenosine is required for sustained inflammasome activation via the A₂A receptor and the HIF-1α pathway |
| Q34744544 | Adenosine-5'-triphosphate (ATP) protects mice against bacterial infection by activation of the NLRP3 inflammasome |
| Q92072181 | Adenovirus VA RNAI Blocks ASC Oligomerization and Inhibits NLRP3 Inflammasome Activation |
| Q39639156 | Adenovirus membrane penetration activates the NLRP3 inflammasome. |
| Q37332628 | Adjuvant effect of cationic liposomes for subunit influenza vaccine: influence of antigen loading method, cholesterol and immune modulators |
| Q38096056 | Adjuvant immunotherapies as a novel approach to bacterial infections |
| Q35090905 | Adjuvanticity of the oil-in-water emulsion MF59 is independent of Nlrp3 inflammasome but requires the adaptor protein MyD88 |
| Q38264288 | Adjuvants and delivery systems for antifungal vaccines: current state and future developments |
| Q36502879 | Adrenergic stimulation alters the expression of inflammasome components and interleukins in primary human monocytes |
| Q88599910 | Advances in Biomaterials for Drug Delivery |
| Q36183332 | Airway epithelial regulation of allergic sensitization in asthma |
| Q33817302 | Alarmins, inflammasomes and immunity |
| Q26861620 | Alcoholic liver disease: pathogenesis, management, and novel targets for therapy |
| Q36093514 | Alkaline phosphatase for treatment of sepsis-induced acute kidney injury: a prospective randomized double-blind placebo-controlled trial |
| Q34006421 | Altered redox state of monocytes from cryopyrin-associated periodic syndromes causes accelerated IL-1beta secretion |
| Q38952803 | Alternative functions for the multifarious inflammasome. |
| Q36757998 | Alternative mechanism for white adipose tissue lipolysis after thermal injury. |
| Q39576961 | Alum interaction with dendritic cell membrane lipids is essential for its adjuvanticity |
| Q64110608 | Amelioration of PM-induced lung toxicity in rats by nutritional supplementation with fish oil and Vitamin E |
| Q59136530 | Amyloid β directly interacts with NLRP3 to initiate inflammasome activation: identification of an intrinsic NLRP3 ligand in a cell-free system |
| Q93014137 | Amyloids in Site-Specific Autoimmune Reactions and Inflammatory Responses |
| Q89595472 | An Acetylation Switch of the NLRP3 Inflammasome Regulates Aging-Associated Chronic Inflammation and Insulin Resistance |
| Q90412015 | An Overview of the Heterogeneity of Major Depressive Disorder: Current Knowledge and Future Prospective |
| Q33911383 | An shRNA-based screen of splicing regulators identifies SFRS3 as a negative regulator of IL-1β secretion |
| Q59136398 | Anakinra Therapy for Non-cancer Inflammatory Diseases |
| Q34675068 | Analysis of the murine immune response to pulmonary delivery of precisely fabricated nano- and microscale particles |
| Q34323818 | Anaplasma phagocytophilum dihydrolipoamide dehydrogenase 1 affects host-derived immunopathology during microbial colonization |
| Q35878129 | Anthrax and the inflammasome |
| Q28481797 | Anthrax lethal factor cleavage of Nlrp1 is required for activation of the inflammasome |
| Q28572221 | Anthrax lethal toxin activates the inflammasome in sensitive rat macrophages |
| Q41867870 | Anthrax toxin induces macrophage death by p38 MAPK inhibition but leads to inflammasome activation via ATP leakage |
| Q33667612 | Anti-CD73 antibody therapy inhibits breast tumor growth and metastasis |
| Q38091182 | Anti-cytokine therapies in T1D: Concepts and strategies |
| Q33744674 | Anti-inflammatory compounds parthenolide and Bay 11-7082 are direct inhibitors of the inflammasome |
| Q56768795 | Antibody-mediated inhibition of integrin α5β1 blocks neurotoxic prion peptide PrP106-126-induced activation of BV2 microglia |
| Q89070492 | Antioxidant and anti-inflammatory capacities of collagen peptides from milkfish (Chanos chanos) scales |
| Q36918159 | Antiviral immune responses in the genital tract: clues for vaccines |
| Q38666600 | Antiviral innate immunity through the lens of systems biology |
| Q38626002 | Antofine suppresses endotoxin-induced inflammation and metabolic disorder via AMP-activated protein kinase. |
| Q35231260 | Apoptotic cells induce NF-κB and inflammasome negative signaling |
| Q47093501 | Applications of reconstituted inflammasomes in a cell-free system to drug discovery and elucidation of the pathogenesis of autoinflammatory diseases. |
| Q37449578 | Arsenic trioxide and other arsenical compounds inhibit the NLRP1, NLRP3, and NAIP5/NLRC4 inflammasomes |
| Q33901562 | Aryl hydrocarbon receptor control of a disease tolerance defence pathway |
| Q28387699 | Asbestos and erionite prime and activate the NLRP3 inflammasome that stimulates autocrine cytokine release in human mesothelial cells |
| Q47795988 | Association of NLRP3 polymorphisms with susceptibility to primary gouty arthritis in a Chinese Han population |
| Q34758946 | Association of TLR4 Gene rs2149356 polymorphism with primary gouty arthritis in a case-control study |
| Q38902064 | Association study of CARD8 (p.C10X) and NLRP3 (p.Q705K) variants with rheumatoid arthritis in French and Tunisian populations. |
| Q55403025 | Atherosclerosis as autoimmune disease. |
| Q35006409 | Atherosclerosis in ApoE-deficient mice progresses independently of the NLRP3 inflammasome |
| Q38816005 | Atrial natriuretic peptide down-regulates LPS/ATP-mediated IL-1β release by inhibiting NF-kB, NLRP3 inflammasome and caspase-1 activation in THP-1 cells. |
| Q48054486 | Atypical Inflammasomes |
| Q33768371 | Auranofin protects against anthrax lethal toxin-induced activation of the Nlrp1b inflammasome |
| Q35558406 | Autoinflammation: translating mechanism to therapy |
| Q36520994 | Autoinflammatory disease reloaded: a clinical perspective |
| Q37733859 | Autophagy and innate immunity: triggering, targeting and tuning |
| Q36499896 | Autophagy and selective deployment of Atg proteins in antiviral defense |
| Q38897741 | Autophagy, Inflammation, and Immunity: A Troika Governing Cancer and Its Treatment |
| Q36116965 | Autophagy, microbial sensing, endoplasmic reticulum stress, and epithelial function in inflammatory bowel disease |
| Q34126944 | Behavioral and genetic investigations of low exploratory behavior in Il18r1(-/-) mice: we can't always blame it on the targeted gene |
| Q37973108 | Bench-to-bedside review: Damage-associated molecular patterns in the onset of ventilator-induced lung injury |
| Q38165936 | Beneficial and Detrimental Roles of NLRs in Carcinogenesis |
| Q59791521 | Betaine Inhibits Interleukin-1β Production and Release: Potential Mechanisms |
| Q55016760 | Betaine in Inflammation: Mechanistic Aspects and Applications. |
| Q39429221 | Beyond infection - Maternal immune activation by environmental factors, microglial development, and relevance for autism spectrum disorders |
| Q38936714 | Biological roles of glycans |
| Q40297124 | Blockade of Notch signaling promotes acetaminophen-induced liver injury. |
| Q37260491 | Blocking toll-like receptor 2 and 4 signaling during a stressor prevents stress-induced priming of neuroinflammatory responses to a subsequent immune challenge. |
| Q42722151 | Borrelia burgdorferi infection regulates CD1 expression in human cells and tissues via IL1-β. |
| Q30496116 | Bothrops snake myotoxins induce a large efflux of ATP and potassium with spreading of cell damage and pain |
| Q36789815 | C/EBPβ-Thr217 Phosphorylation Stimulates Macrophage Inflammasome Activation and Liver Injury |
| Q38473823 | CAPS--pathogenesis, presentation and treatment of an autoinflammatory disease |
| Q33765679 | CARD8 is a negative regulator for NLRP3 inflammasome, but mutant NLRP3 in cryopyrin-associated periodic syndromes escapes the restriction. |
| Q60045986 | CASP4 gene silencing in epithelial cancer cells leads to impairment of cell migration, cell-matrix adhesion and tissue invasion |
| Q39657231 | CCR8 signaling influences Toll-like receptor 4 responses in human macrophages in inflammatory diseases |
| Q34146362 | CD36 participates in PrP(106-126)-induced activation of microglia |
| Q47661727 | COPs and POPs Patrol Inflammasome Activation |
| Q59072636 | Candida Immunity |
| Q33595895 | Canonical Nlrp3 inflammasome links systemic low-grade inflammation to functional decline in aging |
| Q35947488 | Capsular Polysaccharide Is Involved in NLRP3 Inflammasome Activation by Klebsiella pneumoniae Serotype K1 |
| Q44655782 | Carcinoma cuniculatum in course of etanercept: blocking autoimmunity but propagation of carcinogenesis? |
| Q38040046 | Cardiovascular disease and high-mobility group box 1--is a new inflammatory killer in town? |
| Q35826657 | Caspase-1 Dependent IL-1β Secretion and Antigen-Specific T-Cell Activation by the Novel Adjuvant, PCEP. |
| Q41464455 | Caspase-1 activation by NLRP3 inflammasome dampens IL-33-dependent house dust mite-induced allergic lung inflammation |
| Q34505406 | Caspase-1 and IL-1β processing in a teleost fish |
| Q33952490 | Caspase-1 dependent IL-1β secretion is critical for host defense in a mouse model of Chlamydia pneumoniae lung infection |
| Q92558719 | Caspase-1 inflammasome activity in patients with Staphylococcus aureus bacteremia |
| Q39040821 | Caspase-1 promotes monocyte-macrophage differentiation by repressing PPARγ. |
| Q34553081 | Caspase-11 controls interleukin-1β release through degradation of TRPC1. |
| Q34044187 | Caspase-1: an integral regulator of innate immunity |
| Q83060208 | Caspase-5 expression is upregulated in lesional psoriatic skin |
| Q48952209 | Casting the critical regions in nucleotide binding oligomerization domain 2 protein: a signature mediated structural dynamics approach. |
| Q42366543 | Celastrol ameliorates inflammation through inhibition of NLRP3 inflammasome activation |
| Q37776184 | Cell Death and Fibrogenesis |
| Q39269818 | Cell cooperation and role of the P2X₇ receptor in pulmonary inflammation induced by nanoparticles. |
| Q27000347 | Cell death pathways and autophagy in the central nervous system and its involvement in neurodegeneration, immunity and central nervous system infection: to die or not to die--that is the question |
| Q35157045 | Cell stress increases ATP release in NLRP3 inflammasome-mediated autoinflammatory diseases, resulting in cytokine imbalance |
| Q35223235 | Cell surface signaling molecules in the control of immune responses: a tide model. |
| Q52671863 | Cell-Free Assay for Inflammasome Activation. |
| Q40398567 | Cellular Innate Immunity: An Old Game with New Players. |
| Q92404329 | Cellulose nanocrystal cationic derivative induces NLRP3 inflammasome-dependent IL-1β secretion associated with mitochondrial ROS production |
| Q85774794 | Changes in toll-like receptor (TLR)4-NFκB-IL1β signaling in male gout patients might be involved in the pathogenesis of primary gouty arthritis |
| Q57817474 | Characterization and Roles of Cherry Valley Duck NLRP3 in Innate Immunity During Avian Pathogenic Infection |
| Q39653478 | Chemical probing reveals insights into the signaling mechanism of inflammasome activation |
| Q33808933 | Chlamydia muridarum Infection of Macrophages Stimulates IL-1β Secretion and Cell Death via Activation of Caspase-1 in an RIP3-Independent Manner |
| Q33644572 | Cholesterol crystals activate the NLRP3 inflammasome in human macrophages: a novel link between cholesterol metabolism and inflammation |
| Q37700323 | Cholesterol crystals induce complement-dependent inflammasome activation and cytokine release |
| Q37415517 | Cholesterol-dependent cytolysins induce rapid release of mature IL-1beta from murine macrophages in a NLRP3 inflammasome and cathepsin B-dependent manner |
| Q52297206 | Chronic immune stimulation as a contributing cause of chronic disease in opiate addiction including multi-system ageing |
| Q37559660 | Clash of the Cytokine Titans: counter-regulation of interleukin-1 and type I interferon-mediated inflammatory responses |
| Q37361360 | Classical swine fever virus triggers RIG-I and MDA5-dependent signaling pathway to IRF-3 and NF-κB activation to promote secretion of interferon and inflammatory cytokines in porcine alveolar macrophages |
| Q41906826 | Clinical Overlapping in Autoinflammatory Diseases: The Role of Gene Duplication. |
| Q38074354 | Clinical guidelines and definitions of autoinflammatory diseases: contrasts and comparisons with autoimmunity-a comprehensive review |
| Q30222083 | Clinical vaccine development for H5N1 influenza |
| Q47687675 | Co-Localization of Glia Maturation Factor with NLRP3 Inflammasome and Autophagosome Markers in Human Alzheimer's Disease Brain. |
| Q34189287 | Common genetic variations in the NALP3 inflammasome are associated with delayed apoptosis of human neutrophils |
| Q26766681 | Common mechanisms involved in Alzheimer's disease and type 2 diabetes: a key role of chronic bacterial infection and inflammation |
| Q93334093 | Comparative analysis of expression of microbial sensing molecules in mucosal tissues with periodontal disease |
| Q50078106 | Comparative analysis of microbial sensing molecules in mucosal tissues with aging. |
| Q37574503 | Comparative kinetic analyses of gene profiles of naïve CD4+ and CD8+ T cells from young and old animals reveal novel age-related alterations. |
| Q51697175 | Complement C5a potentiates uric acid crystal-induced IL-1β production. |
| Q85959086 | Complement--tapping into new sites and effector systems |
| Q34501875 | Complementing the inflammasome. |
| Q58603887 | Complements are involved in alcoholic fatty liver disease, hepatitis and fibrosis |
| Q37586248 | Comprehensive transcriptome profiling and functional analysis of the frog (Bombina maxima) immune system. |
| Q36305278 | Constitutive Activation of the Nlrc4 Inflammasome Prevents Hepatic Fibrosis and Promotes Hepatic Regeneration after Partial Hepatectomy |
| Q42123554 | Constitutive interferon-inducible protein 16-inflammasome activation during Epstein-Barr virus latency I, II, and III in B and epithelial cells |
| Q36177047 | Continuous Antigenic Stimulation of DO11.10 TCR Transgenic Mice in the Presence or Absence of IL-1β: Possible Implications for Mechanisms of T Cell Depletion in HIV Disease |
| Q45052622 | Contribution of guanine nucleotide exchange factor Vav2 to NLRP3 inflammasome activation in mouse podocytes during hyperhomocysteinemia |
| Q27026513 | Control of adaptive immunity by the innate immune system |
| Q27026744 | Control of innate and adaptive immunity by the inflammasome |
| Q37114315 | Control of the innate immune response by the mevalonate pathway. |
| Q33604905 | Conventional DCs reduce liver ischemia/reperfusion injury in mice via IL-10 secretion |
| Q37475156 | Cooperative assembly of IFI16 filaments on dsDNA provides insights into host defense strategy. |
| Q30641163 | Coronary endothelial dysfunction induced by nucleotide oligomerization domain-like receptor protein with pyrin domain containing 3 inflammasome activation during hypercholesterolemia: beyond inflammation |
| Q37485683 | Critical functions of priming and lysosomal damage for NLRP3 activation |
| Q34132601 | Crohn disease: a current perspective on genetics, autophagy and immunity |
| Q38615394 | Cross-talk between pathogen recognizing Toll-like receptors and immunoglobulin Fc receptors in immunity |
| Q37462492 | Crosstalk between autophagy and inflammasomes |
| Q37323341 | Curcumin Represses NLRP3 Inflammasome Activation via TLR4/MyD88/NF-κB and P2X7R Signaling in PMA-Induced Macrophages |
| Q64067979 | Current Clinical Trials in Pemphigus and Pemphigoid |
| Q29615589 | Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression |
| Q36893463 | Cutting edge: NLRC5-dependent activation of the inflammasome |
| Q89304722 | Cyclic Stretching Exacerbates Tendinitis by Enhancing NLRP3 Inflammasome Activity via F-Actin Depolymerization |
| Q39592518 | Cytoadherence-dependent induction of inflammatory responses by Mycoplasma pneumoniae |
| Q38953841 | Cytokines and T-Cell Homeostasis in HIV Infection. |
| Q34289365 | Cytosolic double-stranded RNA activates the NLRP3 inflammasome via MAVS-induced membrane permeabilization and K+ efflux |
| Q37996224 | Cytosolic surveillance and antiviral immunity |
| Q28741435 | DC priming by M. vaccae inhibits Th2 responses in contrast to specific TLR2 priming and is associated with selective activation of the CREB pathway |
| Q24621930 | DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88 |
| Q90101113 | DUSP6 Inhibitor (E/Z)-BCI Hydrochloride Attenuates Lipopolysaccharide-Induced Inflammatory Responses in Murine Macrophage Cells via Activating the Nrf2 Signaling Axis and Inhibiting the NF-κB Pathway |
| Q90707412 | Damage-associated molecular patterns in trauma |
| Q55018390 | Danger signals in stroke and their role on microglia activation after ischemia. |
| Q55355541 | Danger signals in trauma. |
| Q90167003 | Danger-associated extracellular ATP counters MDSC therapeutic efficacy in acute GVHD |
| Q30380000 | Dangers within: DAMP responses to damage and cell death in kidney disease. |
| Q37411664 | Danggui Buxue Tang Attenuates Tubulointerstitial Fibrosis via Suppressing NLRP3 Inflammasome in a Rat Model of Unilateral Ureteral Obstruction. |
| Q38177269 | Debug Your Bugs - How NLRs Shape Intestinal Host-Microbe Interactions |
| Q51605654 | Decoupling the Direct and Indirect Biological Effects of ZnO Nanoparticles Using a Communicative Dual Cell-Type Tissue Construct. |
| Q40103193 | Dectin-1 Activation during Leishmania amazonensis Phagocytosis Prompts Syk-Dependent Reactive Oxygen Species Production To Trigger Inflammasome Assembly and Restriction of Parasite Replication |
| Q91868242 | Dengue Virus Infection Activates Interleukin-1β to Induce Tissue Injury and Vascular Leakage |
| Q92623270 | Dengue Virus M Protein Promotes NLRP3 Inflammasome Activation To Induce Vascular Leakage in Mice |
| Q28300995 | Deregulation of the NLRP3 inflammasome in hepatic parenchymal cells during liver cancer progression |
| Q53064170 | Designing biomaterials with immunomodulatory properties for tissue engineering and regenerative medicine. |
| Q36205951 | Detection and characterization of mineralo-organic nanoparticles in human kidneys. |
| Q36562107 | Deubiquitinases regulate the activity of caspase-1 and interleukin-1β secretion via assembly of the inflammasome |
| Q40074273 | Development and validation of a house finch interleukin-1β (HfIL-1β) ELISA system |
| Q97544213 | Diabetes induces hepatocyte pyroptosis by promoting oxidative stress-mediated NLRP3 inflammasome activation during liver ischaemia and reperfusion injury |
| Q64098214 | Dicer regulates activation of the NLRP3 inflammasome |
| Q51646342 | Dietary fatty acid composition is sensed by the NLRP3 inflammasome: omega-3 fatty acid (DHA) prevents NLRP3 activation in human macrophages. |
| Q27000798 | Dietary interactions with the bacterial sensing machinery in the intestine: the plant polyphenol case |
| Q30397403 | Differences in Inflammatory Response Induced by Two Representatives of Clades of the Pandemic ST258 Klebsiella pneumoniae Clonal Lineage Producing KPC-Type Carbapenemases |
| Q33774843 | Different Regulation of Interleukin-1 Production and Activity in Monocytes and Macrophages: Innate Memory as an Endogenous Mechanism of IL-1 Inhibition |
| Q35133146 | Differential regulation of proinflammatory mediators following LPS- and ATP-induced activation of monocytes from patients with antiphospholipid syndrome. |
| Q34467670 | Differential requirement for Caspase-1 autoproteolysis in pathogen-induced cell death and cytokine processing |
| Q42216422 | Differential requirement for P2X7R function in IL-17 dependent vs. IL-17 independent cellular immune responses |
| Q28396225 | Differential splicing of the apoptosis-associated speck like protein containing a caspase recruitment domain (ASC) regulates inflammasomes |
| Q64054228 | Diverse small molecules prevent macrophage lysis during pyroptosis |
| Q47102513 | Do fungi have an innate immune response? An NLR-based comparison to plant and animal immune systems. |
| Q48944820 | Dopamine D1 receptor agonist A-68930 inhibits NLRP3 inflammasome activation and protects rats from spinal cord injury-induced acute lung injury. |
| Q35124414 | Doxorubicin and daunorubicin induce processing and release of interleukin-1β through activation of the NLRP3 inflammasome |
| Q37621648 | Dual role for inflammasome sensors NLRP1 and NLRP3 in murine resistance to Toxoplasma gondii |
| Q42202671 | Dynamin inhibition interferes with inflammasome activation and cytokine gene expression in Streptococcus pyogenes-infected human macrophages |
| Q91997458 | E3 ubiquitin ligase Nedd4 is a key negative regulator for non-canonical inflammasome activation |
| Q33589732 | ER stress in Alzheimer's disease: a novel neuronal trigger for inflammation and Alzheimer's pathology |
| Q36242863 | EV71 3D Protein Binds with NLRP3 and Enhances the Assembly of Inflammasome Complex |
| Q36627450 | Early immune events in the induction of allergic contact dermatitis |
| Q34024531 | Ectosomes as modulators of inflammation and immunity |
| Q28391128 | Effect of MWCNT size, carboxylation, and purification on in vitro and in vivo toxicity, inflammation and lung pathology |
| Q43032312 | Effectiveness and safety of infliximab in two cases of severe chondrocalcinosis: nine years of follow-up. |
| Q37997735 | Effector functions of NLRs in the intestine: innate sensing, cell death, and disease |
| Q35125095 | Effects of air pollutants on innate immunity: the role of Toll-like receptors and nucleotide-binding oligomerization domain-like receptors |
| Q35208545 | Effects of ex-vivo and in-vivo treatment with probiotics on the inflammasome in dogs with chronic enteropathy |
| Q33686400 | Effects of nanoporous alumina on inflammatory cell response |
| Q93077662 | Effects of supplemented culture media from solid-state fermented Isaria cicadae on performance, serum biochemical parameters, serum immune indexes, antioxidant capacity and meat quality of broiler chickens |
| Q28392057 | Effects of the Interactions between Dust Exposure and Genetic Polymorphisms in Nalp3, Caspase-1, and IL-1β on the Risk of Silicosis: A Case-Control Study |
| Q85849198 | Elevated expression of NLRP1 and IPAF are related to oral pemphigus vulgaris pathogenesis |
| Q38234944 | Emerging Concepts about NAIP/NLRC4 Inflammasomes |
| Q91867313 | Emerging Roles for NLRC5 in Immune Diseases |
| Q37954811 | Emerging role of innate immunity in organ transplantation part II: potential of damage-associated molecular patterns to generate immunostimulatory dendritic cells. |
| Q37945971 | Emerging role of innate immunity in organ transplantation: part I: evolution of innate immunity and oxidative allograft injury |
| Q36303634 | Emerging roles for cholesterol and lipoproteins in lung disease |
| Q37772578 | Endogenous toll-like receptor ligands and their biological significance |
| Q52599391 | Endosome-associated CRT1 functions early in resistance gene-mediated defense signaling in Arabidopsis and tobacco. |
| Q39102963 | Endothelial NLRP3 inflammasome activation and enhanced neointima formation in mice by adipokine visfatin |
| Q37712377 | Endothelin-1 directs airway remodeling and hyper-reactivity in a murine asthma model. |
| Q37770212 | Enemy at the gates: dendritic cells and immunity to mucosal pathogens |
| Q28384291 | Engagement of fatty acids with Toll-like receptor 2 drives interleukin-1β production via the ASC/caspase 1 pathway in monosodium urate monohydrate crystal-induced gouty arthritis |
| Q36073831 | Enhanced activity of NLRP3 inflammasome in peripheral blood cells of patients with active rheumatoid arthritis |
| Q51118297 | Enhancement of Muramyl Dipeptide-Dependent NOD2 Activity by a Self-Derived Peptide. |
| Q58560900 | Entamoeba histolytica-induced IL-1β secretion is dependent on caspase-4 and gasdermin D |
| Q35638839 | Environmental Basis of Autoimmunity |
| Q28391625 | Environmental Immunology: Lessons Learned from Exposure to a Select Panel of Immunotoxicants |
| Q38167273 | Epigenetic regulation of ASC/TMS1 expression: potential role in apoptosis and inflammasome function |
| Q35940596 | Epithelial cell responses to infection with human papillomavirus |
| Q35866679 | Epithelial cells and innate antifungal defense. |
| Q50699453 | Epithelial immune response in Drosophila malpighian tubules: interplay between Diap2 and ion channels. |
| Q26748995 | Erythropoiesis in Malaria Infections and Factors Modifying the Erythropoietic Response |
| Q46941137 | Estrogen-provided cardiac protection following burn trauma is mediated through a reduction in mitochondria-derived DAMPs |
| Q57652206 | Evaluation of pyroptosis in macrophages using cytosolic delivery of purified flagellin |
| Q57154899 | Evidence of interaction of CARD8 rs2043211 with NALP3 rs35829419 in Crohn's disease |
| Q35992500 | Exposure of Monocytes to Lipoarabinomannan Promotes Their Differentiation into Functionally and Phenotypically Immature Macrophages. |
| Q41043694 | Expression analysis of inflammasomes in experimental models of inflammatory and fibrotic liver disease |
| Q36976299 | Expression of IL-1β in rhesus EAE and MS lesions is mainly induced in the CNS itself |
| Q39293707 | Expression of inflammation-related genes in the lung of BALB/c mice response to H7N9 influenza A virus with different pathogenicity |
| Q38088676 | Expression regulation and function of NLRC5. |
| Q89746353 | Extracellular vesicle-mediated amyloid transfer to neural progenitor cells: implications for RAGE and HIV infection |
| Q42369219 | Factoring the intestinal microbiome into the pathogenesis of autoimmune hepatitis |
| Q40701526 | Fasciola hepatica infection reduces Mycobacterium bovis burden and mycobacterial uptake and suppresses the pro-inflammatory response. |
| Q34152594 | Fatty acid and endotoxin activate inflammasomes in mouse hepatocytes that release danger signals to stimulate immune cells |
| Q89142206 | Fatty and hydroxycarboxylic acid receptors: The missing link of immune response and metabolism in cattle |
| Q34568233 | Fc gamma receptor-TLR cross-talk elicits pro-inflammatory cytokine production by human M2 macrophages |
| Q42012792 | Fingolimod increases CD39-expressing regulatory T cells in multiple sclerosis patients |
| Q42828837 | Fish-oil-derived n-3 PUFAs reduce inflammatory and chemotactic adipokine-mediated cross-talk between co-cultured murine splenic CD8+ T cells and adipocytes. |
| Q28306794 | Follistatin-like protein 1 enhances NLRP3 inflammasome-mediated IL-1β secretion from monocytes and macrophages |
| Q37891775 | Francisella Recognition by Inflammasomes: Differences between Mice and Men. |
| Q37435652 | From cirrhosis to hepatocellular carcinoma: new molecular insights on inflammation and cellular senescence. |
| Q38445061 | From the draining lymph node to the liver: the induction and effector mechanisms of malaria-specific CD8+ T cells |
| Q33904504 | Functional and mechanistic integration of infection and the metabolic syndrome |
| Q104111366 | Functional crosstalk between myeloid Foxo1-β-catenin axis and Hedgehog/Gli1 signaling in oxidative stress response |
| Q36091313 | GVHD-associated, inflammasome-mediated loss of function in adoptively transferred myeloid-derived suppressor cells. |
| Q42240033 | Gal-lectin-dependent contact activates the inflammasome by invasive Entamoeba histolytica |
| Q28270330 | Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion |
| Q38909256 | General Strategies in Inflammasome Biology |
| Q37207965 | Genetic Association for P2X7R rs3751142 and CARD8 rs2043211 Polymorphisms for Susceptibility of Gout in Korean Men: Multi-Center Study |
| Q37836189 | Genetic and molecular basis of inflammasome-mediated disease |
| Q34906747 | Genetic associations with diabetes: meta-analyses of 10 candidate polymorphisms |
| Q38708244 | Genetic variants of PPAR-gamma coactivator 1B augment NLRP3-mediated inflammation in gouty arthritis |
| Q38522796 | Genetic variation in pattern recognition receptors: functional consequences and susceptibility to infectious disease. |
| Q34582211 | Genomic profiling of C/EBPβ2 transformed mammary epithelial cells: a role for nuclear interleukin-1β. |
| Q38746358 | Geoepidemiology and Immunologic Features of Autoinflammatory Diseases: a Comprehensive Review. |
| Q50332623 | Graft-versus-host disease is independent of innate signaling pathways triggered by pathogens in host hematopoietic cells. |
| Q33696637 | Grape seed extract prevents skeletal muscle wasting in interleukin 10 knockout mice |
| Q50670214 | Growth Hormone Receptor Deficiency Protects against Age-Related NLRP3 Inflammasome Activation and Immune Senescence. |
| Q39333658 | Gut-liver axis, cirrhosis and portal hypertension: the chicken and the egg. |
| Q38371533 | Gut-liver axis: role of inflammasomes |
| Q50357559 | Hearing loss in Muckle-Wells syndrome. |
| Q34844755 | Helminths and their implication in sepsis - a new branch of their immunomodulatory behaviour? |
| Q87166842 | Heme induces IL-1β secretion through activating NLRP3 in kidney inflammation |
| Q47368563 | Heparan sulfate inhibits inflammation and improves wound healing by downregulating the NLR family pyrin domain containing 3 (NLRP3) inflammasome in diabetic rats |
| Q39458996 | Hepatitis C virus activates interleukin-1β via caspase-1-inflammasome complex |
| Q38423384 | Hepatitis regulation by the inflammasome signaling pathway |
| Q34147508 | Hepatocyte Death: A Clear and Present Danger |
| Q53429155 | Heterogeneity of subordination of the IL-18/IFN-γ axis to caspase-1 among patients with Crohn's disease. |
| Q33887008 | High fat diet feeding results in gender specific steatohepatitis and inflammasome activation |
| Q38220792 | High-mobility group box-1 in sterile inflammation |
| Q35016934 | Histone deacetylase inhibitors for treating a spectrum of diseases not related to cancer |
| Q47733636 | Histones trigger sterile inflammation by activating the NLRP3 inflammasome |
| Q24631660 | Horror autoinflammaticus: the molecular pathophysiology of autoinflammatory disease (*) |
| Q52647758 | Host Immune Response to Influenza A Virus Infection. |
| Q34764124 | Host response and bacterial virulence factor expression in Pseudomonas aeruginosa and Streptococcus pneumoniae corneal ulcers. |
| Q38037555 | Host- and microbe determinants that may influence the success of S. aureus colonization |
| Q35118610 | How to design effective vaccines: lessons from an old success story |
| Q55092895 | Hsp90 inhibition as a means to inhibit activation of the NLRP3 inflammasome. |
| Q41024163 | Human Gut Microbiota: Toward an Ecology of Disease |
| Q90189609 | Human Tonsil-Derived Mesenchymal Stromal Cells Maintain Proliferating and ROS-Regulatory Properties via Stanniocalcin-1 |
| Q45353531 | Human respiratory syncytial virus viroporin SH: a viral recognition pathway used by the host to signal inflammasome activation |
| Q38611853 | IL - 10 secreted by Mesenchymal stem cells attenuates acute liver failure through inhibiting pyroptosis |
| Q34262561 | IL-1 blockade in autoinflammatory syndromes |
| Q41903813 | IL-1 in Colon Inflammation, Colon Carcinogenesis and Invasiveness of Colon Cancer |
| Q37696955 | IL-1 pathways in inflammation and human diseases |
| Q45060751 | IL-1 receptor accessory protein-Ig/IL-1 receptor type II-Ig heterodimer inhibits IL-1 response more strongly than other IL-1 blocking biopharmaceutical agents |
| Q38124723 | IL-18 in inflammatory and autoimmune disease |
| Q36625188 | IL-1R signaling in dendritic cells replaces pattern-recognition receptors in promoting CD8⁺ T cell responses to influenza A virus |
| Q30251741 | IL-1β at the crossroad between rheumatoid arthritis and type 2 diabetes: may we kill two birds with one stone? |
| Q38074355 | IL-1β biological treatment of familial Mediterranean fever. |
| Q39071077 | IL-1β drives inflammatory responses to propionibacterium acnes in vitro and in vivo. |
| Q42321500 | IL-1β mediates chronic intestinal inflammation by promoting the accumulation of IL-17A secreting innate lymphoid cells and CD4(+) Th17 cells |
| Q34916928 | IL-1β suppresses innate IL-25 and IL-33 production and maintains helminth chronicity. |
| Q37305013 | IL-1β, RAGE and FABP4: targeting the dynamic trio in metabolic inflammation and related pathologies |
| Q36310557 | IL-22, GM-CSF and IL-17 in peripheral CD4+ T cell subpopulations during multiple sclerosis relapses and remission. Impact of corticosteroid therapy |
| Q37659617 | IL-27 acts on DCs to suppress the T cell response and autoimmunity by inducing expression of the immunoregulatory molecule CD39. |
| Q97523301 | INVOLVEMENT OF NLRP3 INFLAMMASOME IN SCHIZOPHRENIA-LIKE BEHAVIOR IN YOUNG ANIMALS AFTER MATERNAL IMMUNE ACTIVATION |
| Q37320087 | IPAF inflammasome is involved in interleukin-1β production from astrocytes, induced by palmitate; implications for Alzheimer's Disease |
| Q34848159 | ISCOMATRIX adjuvant combines immune activation with antigen delivery to dendritic cells in vivo leading to effective cross-priming of CD8+ T cells. |
| Q37733353 | ITAM receptor signaling and the NLRP3 inflammasome in antifungal immunity |
| Q64100565 | Identification and Analysis of Human Microbe-Disease Associations by Matrix Decomposition and Label Propagation |
| Q47666139 | Identification of a selective and direct NLRP3 inhibitor to treat inflammatory disorders |
| Q47116897 | Identification of an Evolutionarily Conserved Ankyrin Domain-Containing Protein, Caiap, Which Regulates Inflammasome-Dependent Resistance to Bacterial Infection. |
| Q40836289 | Identification of specific tethered inhibitors for caspase-5. |
| Q92264971 | Immune Response Resetting in Ongoing Sepsis |
| Q38192633 | Immune and inflammatory pathways in NASH. |
| Q47565961 | Immune aspects of sepsis and hope for new therapeutics |
| Q39214085 | Immune-related gene polymorphisms in pulmonary diseases |
| Q38116992 | Immunity to bovine herpesvirus 1: I. Viral lifecycle and innate immunity |
| Q42621970 | Immunobiotic Lactobacillus strains augment NLRP3 expression in newborn and adult porcine gut-associated lymphoid tissues |
| Q38693925 | Immunology in the liver--from homeostasis to disease |
| Q43456803 | Immunology of contact allergy |
| Q46750532 | Immunology: recognition of a unique partner |
| Q34022013 | Immunomodulatory Effects of dsRNA and Its Potential as Vaccine Adjuvant |
| Q35938891 | Immunoprophylaxis in intensive farming systems: the way forward |
| Q35603131 | Immunosuppressive tumor microenvironment in cervical cancer patients |
| Q38067452 | Immunotherapeutic applications of IL-18. |
| Q36225449 | Impact of molecular weight on the intrinsic immunogenic activity of poly(beta amino esters). |
| Q36041758 | Implications of protein post-translational modifications in IBD. |
| Q83420583 | Improving immunotherapy: revisiting the immunologist's little secret |
| Q33683367 | In macrophages, caspase-1 activation by SopE and the type III secretion system-1 of S. typhimurium can proceed in the absence of flagellin |
| Q34711482 | In vitro reconstitution of the interactions in the PIDDosome |
| Q36856554 | Increased Expression of the NOD-like Receptor Family, Pyrin Domain Containing 3 Inflammasome in Dermatomyositis and Polymyositis is a Potential Contributor to Their Pathogenesis |
| Q64056302 | Increased risk of chronic fatigue syndrome following psoriasis: a nationwide population-based cohort study |
| Q36288105 | Increasing the efficacy of tumor cell vaccines by enhancing cross priming |
| Q99365171 | Indirect regulation of HMGB1 release by gasdermin D |
| Q35754472 | Inducible innate resistance of lung epithelium to infection |
| Q35065280 | Induction of inflammasome-dependent pyroptosis by carbon black nanoparticles |
| Q26800014 | Induction of innate immunity and its perturbation by influenza viruses |
| Q92593866 | Inflammasome Regulates Hematopoiesis through Cleavage of the Master Erythroid Transcription Factor GATA1 |
| Q35518745 | Inflammasome activation and IL-1β target IL-1α for secretion as opposed to surface expression |
| Q96575977 | Inflammasome activation and regulation: toward a better understanding of complex mechanisms |
| Q42083816 | Inflammasome activation in NADPH oxidase defective mononuclear phagocytes from patients with chronic granulomatous disease |
| Q84199421 | Inflammasome activation. The missing link: how the inflammasome senses oxidative stress |
| Q92284769 | Inflammasome activation: a monocyte lineage privilege |
| Q28593473 | Inflammasome adaptor protein Apoptosis-associated speck-like protein containing CARD (ASC) is critical for the immune response and survival in west Nile virus encephalitis |
| Q37738096 | Inflammasome and IL-1beta-mediated disorders |
| Q36969137 | Inflammasome and toll-like receptor signaling in human monocytes after successful cardiopulmonary resuscitation |
| Q47852970 | Inflammasome in drug abuse |
| Q27026882 | Inflammasome in intestinal inflammation and cancer |
| Q36215032 | Inflammasome-Independent NLRP3 Restriction of a Protective Early Neutrophil Response to Pulmonary Tularemia. |
| Q28267534 | Inflammasome-associated nucleotide-binding domain, leucine-rich repeat proteins and inflammatory diseases |
| Q37446814 | Inflammasome-dependent caspase-1 activation in cervical epithelial cells stimulates growth of the intracellular pathogen Chlamydia trachomatis. |
| Q48338179 | Inflammasome-derived IL-1β production induces nitric oxide-mediated resistance to Leishmania |
| Q33782663 | Inflammasome-independent role of apoptosis-associated speck-like protein containing a CARD (ASC) in T cell priming is critical for collagen-induced arthritis |
| Q48235052 | Inflammasome-induced IL-1β secretion in microglia is characterized by delayed kinetics and is only partially dependent on inflammatory caspases. |
| Q36829403 | Inflammasome-mediated autoinflammatory disorders |
| Q35070801 | Inflammasome-mediated inhibition of Listeria monocytogenes-stimulated immunity is independent of myelomonocytic function |
| Q37302656 | Inflammasome-mediated secretion of IL-1β in human monocytes through TLR2 activation; modulation by dietary fatty acids. |
| Q36072651 | Inflammasomes and Intestinal Tumorigenesis |
| Q28067011 | Inflammasomes and Their Role in Innate Immunity of Sexually Transmitted Infections |
| Q37776164 | Inflammasomes and anti-viral immunity |
| Q38971599 | Inflammasomes and its importance in viral infections. |
| Q35332035 | Inflammasomes and the microbiota--partners in the preservation of mucosal homeostasis |
| Q34905606 | Inflammasomes and their activation. |
| Q34474244 | Inflammasomes as mediators of immunity against influenza virus |
| Q37702142 | Inflammasomes as microbial sensors |
| Q34547897 | Inflammasomes as therapeutic targets for Alzheimer's disease |
| Q37655058 | Inflammasomes bridge signaling between pathogen identification and the immune response |
| Q38178692 | Inflammasomes in antiviral immunity: clues for influenza vaccine development |
| Q35660178 | Inflammasomes in cardiovascular diseases |
| Q34043775 | Inflammasomes in host response to protozoan parasites. |
| Q60303389 | Inflammasomes: Pandora's box for sepsis |
| Q37808975 | Inflammasomes: current understanding and open questions |
| Q33861680 | Inflammasomes: molecular regulation and implications for metabolic and cognitive diseases |
| Q24647337 | Inflammasomes: too big to miss |
| Q34769124 | Inflammation driven by tumour-specific Th1 cells protects against B-cell cancer |
| Q36620693 | Inflammation in mice ectopically expressing human Pyogenic Arthritis, Pyoderma Gangrenosum, and Acne (PAPA) Syndrome-associated PSTPIP1 A230T mutant proteins |
| Q26749594 | Inflammation-inducing Factors of Mycoplasma pneumoniae |
| Q45756098 | Inflammatory and Anti-Inflammatory Equilibrium, Proliferative and Antiproliferative Balance: The Role of Cytokines in Multiple Myeloma. |
| Q29615500 | Inflammatory bowel disease |
| Q38018808 | Inflammatory cytokines in heart failure: mediators and markers |
| Q46893422 | Inflammatory pathway genes associated with inter-individual variability in the trajectories of morning and evening fatigue in patients receiving chemotherapy. |
| Q48153081 | Influence of an Allergen-Specific Th17 Response on Remodeling of the Airways. |
| Q37657060 | Influence of microbial environment on autoimmunity. |
| Q35610815 | Influenza A Virus NS1 Protein Inhibits the NLRP3 Inflammasome |
| Q28279385 | Influenza virus activates inflammasomes via its intracellular M2 ion channel |
| Q30398752 | Inhaled innate immune ligands to prevent pneumonia |
| Q36531774 | Inhibition of Alveolar Macrophage Pyroptosis Reduces Lipopolysaccharide-induced Acute Lung Injury in Mice |
| Q89494061 | Inhibition of Amyloid-Beta Production, Associated Neuroinflammation, and Histone Deacetylase 2-Mediated Epigenetic Modifications Prevent Neuropathology in Alzheimer's Disease in vitro Model |
| Q33916468 | Inhibition of Inflammasome-Dependent Interleukin 1β Production by Streptococcal NAD+-Glycohydrolase: Evidence for Extracellular Activity |
| Q36894381 | Inhibition of hyperhomocysteinemia-induced inflammasome activation and glomerular sclerosis by NLRP3 gene deletion |
| Q28394494 | Innate Immune Responses to Nanoparticle Exposure in the Lung |
| Q26801604 | Innate Immunity and Biomaterials at the Nexus: Friends or Foes |
| Q35205885 | Innate and adaptive immune responses to cell death. |
| Q37945209 | Innate antiviral immune responses to hepatitis B virus. |
| Q37694915 | Innate immune recognition in infectious and noninfectious diseases of the lung |
| Q24626598 | Innate immune sensing of DNA viruses |
| Q60700593 | Innate immunity |
| Q54983048 | Innate immunity and effector and regulatory mechanisms involved in allergic contact dermatitis. |
| Q34980214 | Innate immunity and monocyte-macrophage activation in atherosclerosis. |
| Q38120744 | Innate immunity and neuroinflammation |
| Q35084400 | Innate immunity and transplantation tolerance: the potential role of TLRs/NLRs in GVHD |
| Q37999623 | Innate immunity in the control of HIV/AIDS: recent advances and open questions |
| Q33923354 | Innate immunity to influenza virus infection |
| Q37967103 | Innate immunity: ignored for decades, but not forgotten |
| Q84441688 | Innate immunity: quo vadis? |
| Q57207237 | Innate response to hepatitis B virus infection: Observations challenging the concept of a stealth virus |
| Q33804497 | Insights into the innate immunity of the Mediterranean mussel Mytilus galloprovincialis |
| Q38752373 | Interaction of Candida albicans with host cells: virulence factors, host defense, escape strategies, and the microbiota |
| Q37970755 | Interaction of nanoparticles with immunocompetent cells: nanosafety considerations |
| Q37594928 | Interferon-Alpha Promotes Th1 Response and Epithelial Apoptosis via Inflammasome Activation in Human Intestinal Mucosa |
| Q36431053 | Interferon-β therapy against EAE is effective only when development of the disease depends on the NLRP3 inflammasome |
| Q41871311 | Interleukin 1-β, interleukin-1 receptor antagonist, and interleukin 18 in children with acute spontaneous urticaria |
| Q37494902 | Interleukin 1α and the inflammatory process |
| Q28550089 | Interleukin-1 Antagonist Anakinra in Amyotrophic Lateral Sclerosis--A Pilot Study |
| Q37088215 | Interleukin-1 antagonists and other cytokine blockade strategies for type 1 diabetes |
| Q38109212 | Interleukin-1 antagonists for diabetes |
| Q38993264 | Interleukin-1 antagonists in the treatment of autoinflammatory syndromes, including cryopyrin-associated periodic syndrome |
| Q37597282 | Interleukin-1 as a mediator of fatigue in disease: a narrative review |
| Q40376774 | Interleukin-1 cytokines, inflammasomes, NOD-signalosomes and autoinflammation |
| Q24606766 | Interleukin-1 in the pathogenesis and treatment of inflammatory diseases |
| Q64275741 | Interleukin-18 in Health and Disease |
| Q24630062 | Interleukin-36 (IL-36) ligands require processing for full agonist (IL-36α, IL-36β, and IL-36γ) or antagonist (IL-36Ra) activity |
| Q91302959 | Interplay between early-life malnutrition, epigenetic modulation of the immune function and liver diseases |
| Q36085204 | Intra-city Differences in Cardiac Expression of Inflammatory Genes and Inflammasomes in Young Urbanites: A Pilot Study |
| Q28265676 | Intracellular innate immunity in gouty arthritis: role of NALP3 inflammasome |
| Q38423864 | Intracellular signaling of cardiac fibroblasts |
| Q43165910 | Intravital imaging of IL-1beta production in skin. |
| Q36581724 | Intrinsic immunogenicity of rapidly-degradable polymers evolves during degradation |
| Q90265357 | Involvement of NLRP3 and NLRC4 Inflammasome in Uropathogenic E. coli Mediated Urinary Tract Infections |
| Q50648904 | Involvement of c-Abl Kinase in Microglial Activation of NLRP3 Inflammasome and Impairment in Autolysosomal System. |
| Q26744390 | Involvement of matrix metalloproteinases (MMPs) and inflammasome pathway in molecular mechanisms of fibrosis |
| Q42208785 | Ion flux in the lung: virus-induced inflammasome activation |
| Q58570378 | Klotho controls the brain-immune system interface in the choroid plexus |
| Q49206184 | LRP6 targeting suppresses gastric tumorigenesis via P14ARF-Mdm2-P53-dependent cellular senescence. |
| Q41676834 | Lack of the purinergic receptor P2X(7) results in resistance to contact hypersensitivity |
| Q37520116 | Leading a sheltered life: intracellular pathogens and maintenance of vacuolar compartments |
| Q45068348 | Length, but Not Reactive Edges, of Cup-stack MWCNT Is Responsible for Toxicity and Acute Lung Inflammation |
| Q34570348 | Limited role for ASC and NLRP3 during in vivo Salmonella Typhimurium infection. |
| Q39443989 | Limiting inflammation-the negative regulation of NF-κB and the NLRP3 inflammasome |
| Q35042272 | Link between chronic inflammation and human papillomavirus-induced carcinogenesis (Review). |
| Q39565363 | Lipopolysaccharide induces and activates the Nalp3 inflammasome in the liver |
| Q45399633 | Lipopolysaccharide/adenosine triphosphate-mediated signal transduction in the regulation of NLRP3 protein expression and caspase-1-mediated interleukin-1β secretion |
| Q37942172 | Liposomal photosensitizers: potential platforms for anticancer photodynamic therapy |
| Q35134104 | Listeria monocytogenes engineered to activate the Nlrc4 inflammasome are severely attenuated and are poor inducers of protective immunity |
| Q42785062 | Listeria monocytogenes is sensed by the NLRP3 and AIM2 inflammasome |
| Q34163303 | Listeria monocytogenes triggers AIM2-mediated pyroptosis upon infrequent bacteriolysis in the macrophage cytosol. |
| Q48260251 | Listeria monocytogenes: The Impact of Cell Death on Infection and Immunity |
| Q36977730 | Listeria monocytogenes: a promising vehicle for neonatal vaccination |
| Q48323030 | Low-level light emitting diode (LED) therapy suppresses inflammasome-mediated brain damage in experimental ischemic stroke |
| Q53239141 | Lung Aspergillosis in renal cell carcinoma patient treated with sunitinib. |
| Q38810913 | Lymph node - an organ for T-cell activation and pathogen defense. |
| Q36827145 | Lymphoid-tissue stromal cells coordinate innate defense to cytomegalovirus |
| Q39593763 | Lysosomal localization and mechanism of membrane penetration influence nonenveloped virus activation of the NLRP3 inflammasome. |
| Q47649630 | M-CSF induces the expression of a membrane-bound form of IL-18 in a subset of human monocytes differentiating in vitro toward macrophages |
| Q55488915 | MCC950, a specific small molecule inhibitor of NLRP3 inflammasome attenuates colonic inflammation in spontaneous colitis mice. |
| Q33693237 | Macrophage CGI-58 deficiency activates ROS-inflammasome pathway to promote insulin resistance in mice |
| Q41704840 | Macrophage activation-like syndrome: an immunological entity associated with rapid progression to death in sepsis |
| Q26828497 | Macrophages and Uveitis in Experimental Animal Models |
| Q38134101 | Macrophages control innate inflammation |
| Q53220575 | Macrophages from patients with atopic dermatitis show a reduced CXCL10 expression in response to staphylococcal α-toxin. |
| Q35595537 | Macrophages in immunopathology of atherosclerosis: a target for diagnostics and therapy. |
| Q35421025 | Macrophages make me sick: how macrophage activation states influence sickness behavior |
| Q30813096 | Macrophages mediate flagellin induced inflammasome activation and host defense in zebrafish |
| Q35536092 | Manganese superoxide dismutase: guardian of the powerhouse |
| Q38633155 | Mast cells in asthma--state of the art. |
| Q35599347 | Measles virus V protein inhibits NLRP3 inflammasome-mediated interleukin-1β secretion |
| Q42036323 | Mechanism of immunopotentiation and safety of aluminum adjuvants. |
| Q39402899 | Mechanisms and treatments for severe, steroid-resistant allergic airway disease and asthma. |
| Q38817338 | Mechanisms by which obesity impacts upon asthma |
| Q38110539 | Mechanisms of action of adjuvants |
| Q44876003 | Mechanisms of carbon nanotube-induced pulmonary fibrosis: a physicochemical characteristic perspective |
| Q27687785 | Mechanisms of chemical-induced innate immunity in allergic contact dermatitis |
| Q35609312 | Mechanisms of inflammasome activation by Vibrio cholerae secreted toxins vary with strain biotype |
| Q84154578 | Mechanisms of inflammation in gout |
| Q35859536 | Megalin/Cubulin-Lysosome-mediated Albumin Reabsorption Is Involved in the Tubular Cell Activation of NLRP3 Inflammasome and Tubulointerstitial Inflammation |
| Q47098709 | Melatonin as an Anti-Inflammatory Agent Modulating Inflammasome Activation |
| Q38635632 | Melatonin, clock genes and mitochondria in sepsis. |
| Q41097438 | Memory Training Program Decreases the Circulating Level of Cortisol and Pro-inflammatory Cytokines in Healthy Older Adults |
| Q39048543 | Mesenchymal stem/stromal cells inhibit the NLRP3 inflammasome by decreasing mitochondrial reactive oxygen species |
| Q37682953 | Mesocestoides corti intracranial infection as a murine model for neurocysticercosis |
| Q55011065 | Meta-Analysis of Maternal and Fetal Transcriptomic Data Elucidates the Role of Adaptive and Innate Immunity in Preterm Birth. |
| Q47135824 | Meta-analysis of the association between NLRP1 polymorphisms and the susceptibility to vitiligo and associated autoimmune diseases |
| Q26799973 | Mevalonate Pathway Blockade, Mitochondrial Dysfunction and Autophagy: A Possible Link |
| Q36687916 | MicroRNA-454 regulates stromal cell derived factor-1 in the control of the growth of pancreatic ductal adenocarcinoma |
| Q46380108 | Microbiota, NASH, HCC and the potential role of probiotics |
| Q35861527 | Microbiota-Modulated Metabolites Shape the Intestinal Microenvironment by Regulating NLRP6 Inflammasome Signaling. |
| Q37983851 | Microcrystals as DAMPs and their role in joint inflammation |
| Q36547001 | Microglial M1/M2 polarization and metabolic states |
| Q57792126 | Microglial Mincle receptor in the PVN contributes to sympathetic hyperactivity in acute myocardial infarction rat |
| Q34359569 | Microglial phenotype and adaptation |
| Q38072224 | Microparticles and their impact on intestinal immunity |
| Q35124329 | Microvesicular caspase-1 mediates lymphocyte apoptosis in sepsis |
| Q91982321 | Mitochondria and Aging-The Role of Exercise as a Countermeasure |
| Q58596343 | Mitochondria, Oxidative Stress and Innate Immunity |
| Q42056008 | Mitochondria-targeted drugs enhance Nlrp3 inflammasome-dependent IL-1β secretion in association with alterations in cellular redox and energy status |
| Q37667286 | Mitochondrial DNA Activates the NLRP3 Inflammasome and Predisposes to Type 1 Diabetes in Murine Model |
| Q42732446 | Mitochondrial NLRP3 protein induces reactive oxygen species to promote Smad protein signaling and fibrosis independent from the inflammasome. |
| Q36137078 | Mitochondrial ROS Induces Cardiac Inflammation via a Pathway through mtDNA Damage in a Pneumonia-Related Sepsis Model. |
| Q38856957 | Mitochondrial ROS fuel the inflammasome |
| Q61811552 | Mitochondrial Stress-Initiated Aberrant Activation of the NLRP3 Inflammasome Regulates the Functional Deterioration of Hematopoietic Stem Cell Aging |
| Q37996828 | Mitochondrial dysfunction and oxidative stress activate inflammasomes: impact on the aging process and age-related diseases |
| Q37847792 | Mitochondrial reactive oxygen species drive proinflammatory cytokine production |
| Q93062900 | Mitophagy and Innate Immunity in Infection |
| Q35205924 | Mitoxosome: a mitochondrial platform for cross-talk between cellular stress and antiviral signaling. |
| Q26768562 | Modulation of inflammasome activity by Porphyromonas gingivalis in periodontitis and associated systemic diseases |
| Q58784853 | Molecular Targets in Hepatocarcinogenesis and Implications for Therapy |
| Q27310134 | Molecular basis of caspase-1 polymerization and its inhibition by a new capping mechanism. |
| Q37950957 | Molecular battle between host and bacterium: recognition in innate immunity |
| Q26866436 | Molecular mechanisms of inflammasome activation during microbial infections |
| Q33907429 | Molecular mechanisms of liver fibrosis in HIV/HCV coinfection |
| Q26778556 | Molecular mechanisms regulating NLRP3 inflammasome activation |
| Q28397153 | Molecular pathways: targeting mechanisms of asbestos and erionite carcinogenesis in mesothelioma |
| Q44280533 | Molecular signature of the immune and tissue response to non-coding plasmid DNA in skeletal muscle after electrotransfer |
| Q26765189 | Monocyte Activation in Immunopathology: Cellular Test for Development of Diagnostics and Therapy |
| Q26823168 | Monocyte chemotactic protein-1-induced protein-1 (MCPIP1) is a novel multifunctional modulator of inflammatory reactions |
| Q33506630 | Monocyte derived microvesicles deliver a cell death message via encapsulated caspase-1. |
| Q37688255 | Monocyte-derived factors including PLA2G7 induced by macrophage-nasopharyngeal carcinoma cell interaction promote tumor cell invasiveness |
| Q36666383 | Monosodium urate activates Src/Pyk2/PI3 kinase and cathepsin dependent unconventional protein secretion from human primary macrophages |
| Q42790753 | Mouse granzyme K has pro-inflammatory potential. |
| Q33702318 | Mouse models to unravel the role of inhaled pollutants on allergic sensitization and airway inflammation |
| Q42875223 | Multiple interleukin-1beta-converting enzymes contribute to inflammatory arthritis |
| Q33786763 | Multiple roles of Myd88 in the immune response to the plague F1-V vaccine and in protection against an aerosol challenge of Yersinia pestis CO92 in mice |
| Q28740326 | Multiplex immunoassay of lower genital tract mucosal fluid from women attending an urban STD clinic shows broadly increased IL1ß and lactoferrin |
| Q36159273 | Multiplicative interaction of functional inflammasome genetic variants in determining the risk of gout |
| Q39182409 | Muramyl dipeptide mediated activation of human bronchial epithelial cells interacting with basophils: a novel mechanism of airway inflammation |
| Q38070410 | Muramyl dipeptide responsive pathways in Crohn's disease: from NOD2 and beyond |
| Q35191858 | Mutations of the Listeria monocytogenes peptidoglycan N-deacetylase and O-acetylase result in enhanced lysozyme sensitivity, bacteriolysis, and hyperinduction of innate immune pathways |
| Q39529700 | MyD88-dependent TLR1/2 signals educate dendritic cells with gut-specific imprinting properties |
| Q94521960 | Myeloid PTEN promotes chemotherapy-induced NLRP3-inflammasome activation and antitumour immunity |
| Q54225782 | Myeloid-related proteins 8 and 14 contribute to monosodium urate monohydrate crystal-induced inflammation in gout. |
| Q38961205 | Myxoma virus lacking the pyrin-like protein M013 is sensed in human myeloid cells by both NLRP3 and multiple Toll-like receptors, which independently activate the inflammasome and NF-κB innate response pathways |
| Q98386218 | N-acetylcysteine alleviates post-resuscitation myocardial dysfunction and improves survival outcomes via partly inhibiting NLRP3 inflammasome induced-pyroptosis |
| Q36731427 | NADPH oxidase-mediated triggering of inflammasome activation in mouse podocytes and glomeruli during hyperhomocysteinemia |
| Q34529550 | NALP1 influences susceptibility to human congenital toxoplasmosis, proinflammatory cytokine response, and fate of Toxoplasma gondii-infected monocytic cells. |
| Q39607181 | NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux |
| Q40019351 | NF-kappaB: no longer an island, but a piece of a continent |
| Q36964401 | NF-κB pathway activators as potential ageing biomarkers: targets for new therapeutic strategies. |
| Q61955081 | NLR functions beyond pathogen recognition |
| Q34764912 | NLRP1 inflammasome activation induces pyroptosis of hematopoietic progenitor cells |
| Q47126550 | NLRP11 attenuates Toll-like receptor signalling by targeting TRAF6 for degradation via the ubiquitin ligase RNF19A. |
| Q36273965 | NLRP12 Inflammasome Expression in the Rat Brain in Response to LPS during Morphine Tolerance |
| Q35895281 | NLRP3 Inflammasome Activation by Viroporins of Animal Viruses |
| Q34544678 | NLRP3 Inflammasome Activation in the Brain after Global Cerebral Ischemia and Regulation by 17β-Estradiol. |
| Q53172204 | NLRP3 deletion protects against renal fibrosis and attenuates mitochondrial abnormality in mouse with 5/6 nephrectomy. |
| Q37677541 | NLRP3 has a sweet tooth |
| Q35068077 | NLRP3 inflammasome activation by Paracoccidioides brasiliensis |
| Q28389971 | NLRP3 inflammasome activation in murine alveolar macrophages and related lung pathology is associated with MWCNT nickel contamination |
| Q28387817 | NLRP3 inflammasome activation induced by engineered nanomaterials |
| Q48151440 | NLRP3 inflammasome activation is associated with proliferative diabetic retinopathy. |
| Q41595173 | NLRP3 inflammasome activation promotes inflammation-induced carcinogenesis in head and neck squamous cell carcinoma. |
| Q29619524 | NLRP3 inflammasome activation: The convergence of multiple signalling pathways on ROS production? |
| Q37220437 | NLRP3 inflammasome and host protection against bacterial infection |
| Q90262460 | NLRP3 inflammasome blockade reduces adipose tissue inflammation and extracellular matrix remodeling |
| Q87982723 | NLRP3 inflammasome inhibition ameliorates tubulointerstitial injury in the remnant kidney model |
| Q37422647 | NLRP3 inflammasome knockout mice are protected against ischemic but not cisplatin-induced acute kidney injury |
| Q91387247 | NLRP3 inflammasome pathway is involved in olfactory bulb pathological alteration induced by MPTP |
| Q29615704 | NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals |
| Q24604235 | NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice |
| Q52715020 | NLRP3 promotes tumor growth and metastasis in human oral squamous cell carcinoma. |
| Q36867370 | NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22. |
| Q60935590 | NLRP3-Dependent and -Independent Processing of Interleukin (IL)-1β in Active Ulcerative Colitis |
| Q89047710 | NLRP3/ASC-mediated alveolar macrophage pyroptosis enhances HMGB1 secretion in acute lung injury induced by cardiopulmonary bypass |
| Q34230280 | NLRP7 inter-domain interactions: the NACHT-associated domain is the physical mediator for oligomeric assembly |
| Q35169896 | NLRs in immune privileged sites |
| Q89529534 | NOD-like Receptors in the Eye: Uncovering Its Role in Diabetic Retinopathy |
| Q35948586 | NOD2 triggers an interleukin-32-dependent human dendritic cell program in leprosy |
| Q34995164 | NSD1 mitigates caspase-1 activation by listeriolysin O in macrophages |
| Q91667785 | Nanomaterial-Based Vaccine Adjuvants |
| Q37850519 | Natural products and the search for novel vaccine adjuvants |
| Q34846646 | Nedd8 regulates inflammasome-dependent caspase-1 activation |
| Q47217292 | Negative regulation of MAVS-mediated innate immune response by ASC. |
| Q38092025 | Negative regulation of NLRP3 inflammasome signaling |
| Q30500145 | Neuroinflammation leads to region-dependent alterations in astrocyte gap junction communication and hemichannel activity |
| Q38975577 | Neuroinflammation, immune system and Alzheimer disease: searching for the missing link |
| Q35720256 | Neuropathic Pain Phenotype Does Not Involve the NLRP3 Inflammasome and Its End Product Interleukin-1β in the Mice Spared Nerve Injury Model |
| Q35804151 | Neutrophil serine proteases promote IL-1β generation and injury in necrotizing crescentic glomerulonephritis |
| Q47592796 | Neutrophils drive alveolar macrophage IL-1β release during respiratory viral infection. |
| Q38076334 | Neutrophils, IL-1β, and gout: is there a link? |
| Q38121074 | New Insights in the Immunobiology of IL-1 Family Members |
| Q35026692 | New and improved strategies for the treatment of gout |
| Q52624393 | New insights into Nod-like receptors (NLRs) in liver diseases. |
| Q59090498 | New mitochondrial DNA synthesis enables NLRP3 inflammasome activation |
| Q52578738 | New use for CETSA: monitoring innate immune receptor stability via post-translational modification by OGT. |
| Q44248847 | No evidence for involvement of the toll-like receptor (TLR) 4 gene Asp299Gly and Thr399Ile polymorphisms in susceptibility to primary gouty arthritis |
| Q35582494 | Nod-like receptor protein-3 inflammasome plays an important role during early stages of wound healing |
| Q55116645 | Nod2 is required for antigen-specific humoral responses against antigens orally delivered using a recombinant Lactobacillus vaccine platform. |
| Q92984193 | Non-canonical NLRP3 inflammasome activation and IL-1β signaling are necessary to L. amazonensis control mediated by P2X7 receptor and leukotriene B4 |
| Q36392069 | Nonpathogenic Lactobacillus rhamnosus activates the inflammasome and antiviral responses in human macrophages |
| Q28069227 | Novel concept of iSALT (inducible skin-associated lymphoid tissue) in the elicitation of allergic contact dermatitis |
| Q36688203 | Novel insights into molecular mechanisms of abruption-induced preterm birth |
| Q28081241 | Novel insights into the role of immune cells in skin and inducible skin-associated lymphoid tissue (iSALT) |
| Q88990365 | Novel insights into the role of inflammasomes in autoimmune and metabolic rheumatic diseases |
| Q60042076 | Novel macrophage polarization model: from gene expression to identification of new anti-inflammatory molecules |
| Q37781515 | Nuclear Receptors, Inflammation, and Neurodegenerative Diseases |
| Q38231610 | Nucleic acid sensing and beyond: virtues and vices of high-mobility group box 1. |
| Q26997784 | Obesity, fatty liver disease and intestinal microbiota |
| Q44846869 | Octacalcium phosphate crystals induce inflammation in vivo through interleukin-1 but independent of the NLRP3 inflammasome in mice |
| Q38038253 | Ocular manifestations of the autoinflammatory syndromes |
| Q55447541 | Oridonin is a covalent NLRP3 inhibitor with strong anti-inflammasome activity. |
| Q82297572 | Osteoarthritis: Crystal-gazing into the pathogenesis of osteoarthritis |
| Q28975785 | Overexpressed NLRC3 acts as an anti-inflammatory cytosolic protein |
| Q39079743 | OxLDL-induced IL-1 beta secretion promoting foam cells formation was mainly via CD36 mediated ROS production leading to NLRP3 inflammasome activation |
| Q37830940 | Oxidation-specific epitopes are danger-associated molecular patterns recognized by pattern recognition receptors of innate immunity |
| Q41526360 | Oxidative Stress-Mediated Atherosclerosis: Mechanisms and Therapies |
| Q39349571 | Oxidative stress and reactive oxygen species in endothelial dysfunction associated with cardiovascular and metabolic diseases. |
| Q27490449 | Oxidized Hemoglobin Is an Endogenous Proinflammatory Agonist That Targets Vascular Endothelial Cells |
| Q29619852 | Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis |
| Q46237880 | P17, an Original Host Defense Peptide from Ant Venom, Promotes Antifungal Activities of Macrophages through the Induction of C-Type Lectin Receptors Dependent on LTB4-Mediated PPARγ Activation. |
| Q21285096 | P2X7 receptor activation induces reactive oxygen species formation and cell death in murine EOC13 microglia |
| Q39270880 | P2X7 receptor activation induces reactive oxygen species formation in erythroid cells |
| Q37435917 | PADI4 haplotypes in association with RA Mexican patients, a new prospect for antigen modulation |
| Q34049431 | PIDD mediates and stabilizes the interaction between RAIDD and caspase-2 for the PIDDosome assembly |
| Q28818003 | PKR promotes choroidal neovascularization via upregulating the PI3K/Akt signaling pathway in VEGF expression |
| Q91710918 | PTPN2 as a promoter of colon carcinoma via reduction of inflammasome activation |
| Q41670079 | PTPN22 regulates NLRP3-mediated IL1B secretion in an autophagy-dependent manner |
| Q50143105 | PTX3, a Humoral Pattern Recognition Molecule, in Innate Immunity, Tissue Repair, and Cancer. |
| Q37878390 | Parthenolide, a sesquiterpene lactone, expresses multiple anti-cancer and anti-inflammatory activities. |
| Q23919994 | Particle length-dependent titanium dioxide nanomaterials toxicity and bioactivity |
| Q26798034 | Pattern Recognition Receptors in Cancer Progression and Metastasis |
| Q38167648 | Pattern recognition receptors in innate immunity, host defense, and immunopathology |
| Q37981769 | Pattern recognition receptors: sentinels in innate immunity and targets of new vaccine adjuvants |
| Q26991941 | Pattern-recognition receptors and gastric cancer |
| Q40071267 | Periodic Fever with Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis Syndrome Is Associated with a CARD8 Variant Unable To Bind the NLRP3 Inflammasome. |
| Q38777758 | Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis (PFAPA) Syndrome: a Review of the Pathogenesis |
| Q38674213 | Pharmacological treatment options for cryopyrin-associated periodic syndromes |
| Q36745305 | Phosphorylation of the adaptor ASC acts as a molecular switch that controls the formation of speck-like aggregates and inflammasome activity |
| Q46432664 | Plant Lectins Activate the NLRP3 Inflammasome To Promote Inflammatory Disorders. |
| Q37763999 | Plasticity in programming of effector and memory CD8 T-cell formation |
| Q33750041 | Pneumolysin activates the NLRP3 inflammasome and promotes proinflammatory cytokines independently of TLR4. |
| Q33916170 | Polyene macrolide antifungal drugs trigger interleukin-1β secretion by activating the NLRP3 inflammasome |
| Q58068781 | Polyhydroxylated Metallofullerenols Stimulate IL-1β Secretion of Macrophage through TLRs/MyD88/NF-κB Pathway and NLRP3Inflammasome Activation |
| Q36240780 | Porphyromonas gingivalis activates NFκB and MAPK pathways in human oral epithelial cells |
| Q40489303 | Porphyromonas gingivalis attenuates ATP-mediated inflammasome activation and HMGB1 release through expression of a nucleoside-diphosphate kinase. |
| Q42323962 | Post-transcriptional inhibition of luciferase reporter assays by the Nod-like receptor proteins NLRX1 and NLRC3. |
| Q90212908 | Prdx4 limits caspase-1 activation and restricts inflammasome-mediated signaling by extracellular vesicles |
| Q39260594 | Prion protein participates in the regulation of classical and alternative activation of BV2 microglia |
| Q90198037 | Prolonged treatment with the synthetic glucocorticoid methylprednisolone affects adrenal steroidogenic function and response to inflammatory stress in the rat |
| Q57272998 | Proteases in Allergy |
| Q57065905 | Protective Role of Autophagy in Nlrp3 Inflammasome Activation and Medial Thickening of Mouse Coronary Arteries |
| Q92154148 | Protopine Protects Mice against LPS-Induced Acute Kidney Injury by Inhibiting Apoptosis and Inflammation via the TLR4 Signaling Pathway |
| Q36195845 | Pseudomonas aeruginosa pilin activates the inflammasome |
| Q35217392 | Pulmonary and systemic inflammatory responses to intra-amniotic IL-1α in fetal sheep |
| Q23919996 | Purification and sidewall functionalization of multiwalled carbon nanotubes and resulting bioactivity in two macrophage models |
| Q36923670 | Purinergic Signaling and the Immune Response in Sepsis: A Review |
| Q33908383 | Pyrin-only protein 2 limits inflammation but improves protection against bacteria. |
| Q60212390 | Pyroptosis Induction and Detection |
| Q46582632 | Quantitative expression of RIG-like helicase, NOD-like receptor and inflammasome-related mRNAs in humans and mice. |
| Q33904023 | Quantitative subcellular proteome and secretome profiling of influenza A virus-infected human primary macrophages |
| Q46612218 | Quercetin suppresses NLRP3 inflammasome activation and attenuates histopathology in a rat model of spinal cord injury |
| Q57040838 | RAIDD mutations underlie the pathogenesis of thin lissencephaly (TLIS) |
| Q34345194 | RETRACTED: Innate immune activation by inhaled lipopolysaccharide, independent of oxidative stress, exacerbates silica-induced pulmonary fibrosis in mice |
| Q24315639 | RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate |
| Q33619299 | RNA and β-hemolysin of group B Streptococcus induce interleukin-1β (IL-1β) by activating NLRP3 inflammasomes in mouse macrophages. |
| Q38946818 | RNA viruses promote activation of the NLRP3 inflammasome through a RIP1-RIP3-DRP1 signaling pathway. |
| Q39786986 | Rab39a binds caspase-1 and is required for caspase-1-dependent interleukin-1beta secretion |
| Q34140548 | Rac1 regulates the NLRP3 inflammasome which mediates IL-1beta production in Chlamydophila pneumoniae infected human mononuclear cells |
| Q28396273 | Reactive oxygen species in inflammation and tissue injury |
| Q28076650 | Recent Advances of the NLRP3 Inflammasome in Central Nervous System Disorders |
| Q96953619 | Receptors Mediating Host-Microbiota Communication in the Metaorganism: The Invertebrate Perspective |
| Q34080884 | Recognition of virus infection and innate host responses to viral gene therapy vectors |
| Q58695160 | Recombinant human proteoglycan-4 reduces phagocytosis of urate crystals and downstream nuclear factor kappa B and inflammasome activation and production of cytokines and chemokines in human and murine macrophages |
| Q38551809 | Redox stress unbalances the inflammatory cytokine network: role in autoinflammatory patients and healthy subjects |
| Q41658682 | Redundant and cooperative interactions between TLR5 and NLRC4 in protective lung mucosal immunity against Pseudomonas aeruginosa. |
| Q34044445 | Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense against Salmonella |
| Q39140447 | Regiospecific methylation of a dietary flavonoid scaffold selectively enhances IL-1β production following Toll-like receptor 2 stimulation in THP-1 monocytes |
| Q47146914 | Regulation and Sensing of Inflammasomes and Their Impact on Intestinal Health |
| Q41463764 | Regulation of Treg-associated CD39 in multiple sclerosis and effects of corticotherapy during relapse |
| Q34659642 | Regulation of adaptive immunity by the innate immune system |
| Q37750913 | Regulation of inflammasome activity. |
| Q38253147 | Regulation of innate immunity by the molecular machinery of macroautophagy |
| Q31141885 | Regulation of innate responses during pre-patent schistosome infection provides an immune environment permissive for parasite development |
| Q91772526 | Regulation of lung immunity by dendritic cells: Implications for asthma, chronic obstructive pulmonary disease and infectious disease |
| Q44744224 | Regulation of neutrophil apoptosis differs after in vivo transmigration to skin chambers and synovial fluid: a role for inflammasome-dependent interleukin-1β release. |
| Q38693569 | Regulation of xanthine dehydrogensase gene expression and uric acid production in human airway epithelial cells. |
| Q60921906 | Reprogramming the adjuvant properties of aluminum oxyhydroxide with nanoparticle technology |
| Q47916938 | Research of differential expression of sIL1RAP in low-grade gliomas between children and adults. |
| Q37810600 | Respective roles of TLR, RIG-I and NLRP3 in influenza virus infection and immunity: impact on vaccine design |
| Q35805767 | Resveratrol pretreatment protects rat hearts from ischemia/reperfusion injury partly via a NALP3 inflammasome pathway |
| Q27001120 | Review of experimental animal models of biliary acute pancreatitis and recent advances in basic research |
| Q34141940 | Ricin Toxin Activates the NALP3 Inflammasome |
| Q35557377 | Rilonacept in the management of cryopyrin-associated periodic syndromes (CAPS). |
| Q37983640 | Role and function of macrophages in the metabolic syndrome |
| Q90347811 | Role of Inflammasomes in Kidney Diseases via Both Canonical and Non-canonical Pathways |
| Q36712641 | Role of caspase-1 in regulation of triglyceride metabolism. |
| Q42279289 | Role of ginsenosides, the main active components of Panax ginseng, in inflammatory responses and diseases |
| Q38209324 | Role of innate immune response in non-alcoholic Fatty liver disease: metabolic complications and therapeutic tools |
| Q35495434 | Role of the NLRP3 inflammasome in the transient release of IL-1β induced by monosodium urate crystals in human fibroblast-like synoviocytes |
| Q38522801 | Role of virulence factors on host inflammatory response induced by diarrheagenic Escherichia coli pathotypes |
| Q34973392 | S100A8 and S100A9 induce cytokine expression and regulate the NLRP3 inflammasome via ROS-dependent activation of NF-κB(1.). |
| Q107981993 | SARS-CoV-2 N protein promotes NLRP3 inflammasome activation to induce hyperinflammation |
| Q100416003 | SENP7 knockdown inhibited pyroptosis and NF-κB/NLRP3 inflammasome pathway activation in Raw 264.7 cells |
| Q90427150 | STING promotes NLRP3 localization in ER and facilitates NLRP3 deubiquitination to activate the inflammasome upon HSV-1 infection |
| Q37733331 | SYK kinase signaling and the NLRP3 inflammasome in antifungal immunity |
| Q50900027 | Salivary Levels of NLRP3 Inflammasome-Related Proteins as Potential Biomarkers of Periodontal Clinical Status. |
| Q39002277 | Sebum, inflammasomes and the skin: current concepts and future perspective |
| Q56551568 | Sendai Virus V Protein Inhibits the Secretion of Interleukin-1β by Preventing NLRP3 Inflammasome Assembly |
| Q36253171 | Sensing and reacting to microbes through the inflammasomes |
| Q37733350 | Sensing cytoplasmic danger signals by the inflammasome |
| Q37925073 | Sensing damage by the NLRP3 inflammasome |
| Q26853544 | Sepsis-induced Cardiac Mitochondrial Damage and Potential Therapeutic Interventions in the Elderly |
| Q33627261 | Serum apoprotein A1 levels are inversely associated with disease activity in gout: From a southern Chinese Han population |
| Q57213668 | Serum uric acid level is not associated with osteoarthritis in Korean population: data from the Seventh Korea National Health and Nutrition Examination Survey 2016 |
| Q37834022 | Setting up TRAPS. |
| Q36162879 | Severe Changes in Thymic Microenvironment in a Chronic Experimental Model of Paracoccidioidomycosis |
| Q39271570 | Sevoflurane combined with ATP activates caspase-1 and triggers caspase-1-dependent pyroptosis in murine J774 macrophages |
| Q36410999 | Shiga Toxins Activate the NLRP3 Inflammasome Pathway To Promote Both Production of the Proinflammatory Cytokine Interleukin-1β and Apoptotic Cell Death |
| Q94588769 | Should we stimulate or suppress immune responses in COVID-19? Cytokine and anti-cytokine interventions |
| Q37702144 | Signaling by ROS drives inflammasome activation |
| Q39398295 | Simultaneous targeting of toll- and nod-like receptors induces effective tumor-specific immune responses |
| Q35147045 | Since there are PAMPs and DAMPs, there must be SAMPs? Glycan “self-associated molecular patterns” dampen innate immunity, but pathogens can mimic them |
| Q38450509 | Sjögren's syndrome patients with ectopic germinal centers present with a distinct salivary proteome. |
| Q37062344 | Skin Immunity to Candida albicans |
| Q39379300 | Skin Immunity. |
| Q34165173 | Skin immune sentinels in health and disease |
| Q37644622 | Skin symptoms as diagnostic clue for autoinflammatory diseases. |
| Q26769682 | Small Heterodimer Partner and Innate Immune Regulation |
| Q38770923 | Soluble Uric Acid Activates the NLRP3 Inflammasome. |
| Q41570690 | Sphingosine-1-phosphate receptor-2 function in myeloid cells regulates vascular inflammation and atherosclerosis |
| Q30525355 | Spontaneous formation of IpaB ion channels in host cell membranes reveals how Shigella induces pyroptosis in macrophages |
| Q34130857 | Stable extracellular RNA fragments of Mycobacterium tuberculosis induce early apoptosis in human monocytes via a caspase-8 dependent mechanism |
| Q36332700 | Staphylococcus aureus Panton-Valentine leukocidin induces an inflammatory response in human phagocytes via the NLRP3 inflammasome |
| Q33510340 | Staphylococcus aureus alpha-hemolysin activates the NLRP3-inflammasome in human and mouse monocytic cells |
| Q38783989 | Sterile inflammation induced by Carbopol elicits robust adaptive immune responses in the absence of pathogen-associated molecular patterns |
| Q37702140 | Sterile inflammatory responses mediated by the NLRP3 inflammasome |
| Q92481375 | Streptolysin O Induces the Ubiquitination and Degradation of Pro-IL-1β |
| Q34869746 | Stress induces the danger-associated molecular pattern HMGB-1 in the hippocampus of male Sprague Dawley rats: a priming stimulus of microglia and the NLRP3 inflammasome. |
| Q27013816 | Stress sounds the alarmin: The role of the danger-associated molecular pattern HMGB1 in stress-induced neuroinflammatory priming |
| Q35860660 | Stress-activated Dendritic Cells (DC) Induce Dual Interleukin (IL)-15- and IL1β-mediated Pathways, Which May Elicit CD4+ Memory T Cells and Interferon (IFN)-stimulated Genes. |
| Q38086372 | Stress-induced glucocorticoids as a neuroendocrine alarm signal of danger |
| Q28071417 | Stress-induced neuroinflammatory priming: A liability factor in the etiology of psychiatric disorders |
| Q38909260 | Structural Mechanisms in NLR Inflammasome Assembly and Signaling |
| Q27671760 | Structural and Functional Analysis of the NLRP4 Pyrin Domain |
| Q28250563 | Structural mechanisms of inflammasome assembly |
| Q27684604 | Structures of the NLRP14 pyrin domain reveal a conformational switch mechanism regulating its molecular interactions |
| Q27025594 | Subversion of host recognition and defense systems by Francisella spp |
| Q41721216 | Subversion of human intestinal mucosa innate immunity by a Crohn's disease-associated E. coli |
| Q39612410 | Suppression of NLRP3 Inflammasome Activation Ameliorates Chronic Kidney Disease-Induced Cardiac Fibrosis and Diastolic Dysfunction |
| Q33587520 | Susceptibility to anthrax lethal toxin-induced rat death is controlled by a single chromosome 10 locus that includes rNlrp1 |
| Q37597048 | Sustained inflammasome activity in macrophages impairs wound healing in type 2 diabetic humans and mice |
| Q42872553 | Synergism of NOD2 and NLRP3 activators promotes a unique transcriptional profile in murine dendritic cells. |
| Q51158523 | Synthesis and Biological Evaluation of Novel Benzimidazole Derivatives and Analogs Targeting the NLRP3 Inflammasome. |
| Q33715213 | T cell-intrinsic role of IL-6 signaling in primary and memory responses |
| Q35210606 | TLR-2 and TLR-9 are sensors of apoptosis in a mouse model of doxorubicin-induced acute inflammation |
| Q34147516 | TLR2/MyD88/NF-κB pathway, reactive oxygen species, potassium efflux activates NLRP3/ASC inflammasome during respiratory syncytial virus infection |
| Q34451414 | TLR5 activation induces secretory interleukin-1 receptor antagonist (sIL-1Ra) and reduces inflammasome-associated tissue damage |
| Q35085962 | TLR9 and the NLRP3 inflammasome link acinar cell death with inflammation in acute pancreatitis |
| Q34937708 | TNF-Α may mediate inflammasome activation in the absence of bacterial infection in more than one way. |
| Q48022132 | TNF-α potentiates uric acid-induced interleukin-1β (IL-1β) secretion in human neutrophils |
| Q41927259 | TNFalpha shedding and epidermal inflammation are controlled by Jun proteins |
| Q89575217 | TRP Channel Involvement in Salivary Glands-Some Good, Some Bad |
| Q26795462 | TRPM2 Channel-Mediated ROS-Sensitive Ca(2+) Signaling Mechanisms in Immune Cells |
| Q37117804 | Target deletion of complement component 9 attenuates antibody-mediated hemolysis and lipopolysaccharide (LPS)-induced acute shock in mice |
| Q34167205 | Targeting cytokines in inflammatory diseases: focus on interleukin-1-mediated autoinflammation |
| Q57022694 | Targeting of NLRP3 inflammasome with gene editing for the amelioration of inflammatory diseases |
| Q27023252 | Targeting the redox balance in inflammatory skin conditions |
| Q60923395 | Tat-ATOX1 inhibits inflammatory responses via regulation of MAPK and NF-κB pathways |
| Q34281678 | Technical advance: Caspase-1 activation and IL-1β release correlate with the degree of lysosome damage, as illustrated by a novel imaging method to quantify phagolysosome damage. |
| Q39343545 | Temperature and drug treatments in mevalonate kinase deficiency: an ex vivo study |
| Q41525172 | Teuvincenone F Suppresses LPS-Induced Inflammation and NLRP3 Inflammasome Activation by Attenuating NEMO Ubiquitination |
| Q29622833 | The AIM2 inflammasome is critical for innate immunity to Francisella tularensis |
| Q29614469 | The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses |
| Q46238323 | The AIM2 inflammasome: Sensor of pathogens and cellular perturbations |
| Q52332673 | The ATP-P2X7 Signaling Axis Is an Essential Sentinel for Intracellular Clostridium difficile Pathogen-Induced Inflammasome Activation. |
| Q28554605 | The Biophysical Characterisation and SAXS Analysis of Human NLRP1 Uncover a New Level of Complexity of NLR Proteins |
| Q90458248 | The C5a/C5aR2 axis promotes renal inflammation and tissue damage |
| Q38517487 | The CARD plays a critical role in ASC foci formation and inflammasome signalling |
| Q24298464 | The CLRX.1/NOD24 (NLRP2P) pseudogene codes a functional negative regulator of NF-κB, pyrin-only protein 4 |
| Q49920469 | The Circulating Protease Persephone Is an Immune Sensor for Microbial Proteolytic Activities Upstream of the Drosophila Toll Pathway. |
| Q39123220 | The DHX33 RNA helicase senses cytosolic RNA and activates the NLRP3 inflammasome |
| Q57177982 | The Future of IL-1 Targeting in Kidney Disease |
| Q37676929 | The IL-1 family: regulators of immunity |
| Q39292960 | The IL-1-dependent sterile inflammatory response has a substantial caspase-1-independent component that requires cathepsin C. |
| Q38839551 | The IRAK-ERK-p67phox-Nox-2 axis mediates TLR4, 2-induced ROS production for IL-1β transcription and processing in monocytes |
| Q47367020 | The Imbalance between n-6/n-3 Polyunsaturated Fatty Acids and Inflammatory Bowel Disease: A Comprehensive Review and Future Therapeutic Perspectives |
| Q38901677 | The Immune System and the Role of Inflammation in Perinatal Depression. |
| Q35891957 | The Importance of NLRP3 Inflammasome in Heart Failure |
| Q28568698 | The NALP1 inflammasome controls cytokine production and nociception in a rat fracture model of complex regional pain syndrome |
| Q36088252 | The NALP3 inflammasome is involved in neurotoxic prion peptide-induced microglial activation |
| Q41411108 | The NLRP12 inflammasome recognizes Yersinia pestis |
| Q38963273 | The NLRP3 Inflammasome Has a Critical Role in Peritoneal Dialysis-Related Peritonitis |
| Q38779167 | The NLRP3 and NLRP1 inflammasomes are activated in Alzheimer's disease. |
| Q42779770 | The NLRP3 inflammasome detects encephalomyocarditis virus and vesicular stomatitis virus infection |
| Q29616026 | The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance |
| Q41809689 | The NLRP3 inflammasome is active but not essential in endotoxin-induced uveitis |
| Q34455462 | The NLRP3 inflammasome promotes renal inflammation and contributes to CKD. |
| Q37675505 | The NLRP3 inflammasome: a sensor for metabolic danger? |
| Q33717170 | The NOD-like receptor signalling pathway in Helicobacter pylori infection and related gastric cancer: a case-control study and gene expression analyses |
| Q37444372 | The Nlrp3 inflammasome promotes age-related thymic demise and immunosenescence |
| Q37194967 | The Nlrp3 inflammasome regulates acute graft-versus-host disease |
| Q41444442 | The P2X7 Receptor Contributes to the Development of the Exacerbated Inflammatory Response Associated with Sepsis. |
| Q48332393 | The Phagocytic Function of Macrophage-Enforcing Innate Immunity and Tissue Homeostasis. |
| Q55344660 | The Pivotal Role of DNA Repair in Infection Mediated-Inflammation and Cancer. |
| Q47341459 | The Pore-Forming Protein Gasdermin D Regulates Interleukin-1 Secretion from Living Macrophages. |
| Q38928554 | The Recombinant BCG ΔureC::hly Vaccine Targets the AIM2 Inflammasome to Induce Autophagy and Inflammation. |
| Q41836016 | The Recombinant Bacille Calmette-Guérin Vaccine VPM1002: Ready for Clinical Efficacy Testing |
| Q26749025 | The Relationship between NALP3 and Autoinflammatory Syndromes |
| Q64095098 | The Role of Connexin and Pannexin Channels in Perinatal Brain Injury and Inflammation |
| Q36662082 | The SYK tyrosine kinase: a crucial player in diverse biological functions |
| Q91639014 | The Secreted Virulence Factor NADase of Group A Streptococcus Inhibits P2X7 Receptor-Mediated Release of IL-1β |
| Q33996553 | The TLR4/TRIF-Mediated Activation of NLRP3 Inflammasome Underlies Endotoxin-Induced Liver Injury in Mice |
| Q37633282 | The battlefield of perforin/granzyme cell death pathways. |
| Q37899787 | The biology of interleukin-1: emerging concepts in the regulation of the actin cytoskeleton and cell junction dynamics |
| Q37428424 | The characterization of sponge NLRs provides insight into the origin and evolution of this innate immune gene family in animals |
| Q64104128 | The classical NLRP3 inflammasome controls FADD unconventional secretion through microvesicle shedding |
| Q91592665 | The complex functioning of the complement system in xenotransplantation |
| Q38866187 | The contribution of inflammasome components on macrophage response to surface nanotopography and chemistry |
| Q37702155 | The controversial relationship between NLRP3, alum, danger signals and the next-generation adjuvants. |
| Q38175384 | The effect of inflammatory cytokines in alcoholic liver disease. |
| Q90295724 | The effects of barium concentration levels on the pulmonary inflammatory response in a rat model of aspiration |
| Q38177259 | The emerging Pannexin 1 signalome: a new nexus revealed? |
| Q37802305 | The emerging role of interleukin-1β in autoinflammatory diseases |
| Q36096120 | The evolutionary landscape of cytosolic microbial sensors in humans |
| Q39061008 | The function of NOD-like receptors in central nervous system diseases |
| Q38097500 | The genetics of innate immunity sensors and human disease |
| Q37991392 | The immune response to severe bacterial infections: consequences for therapy |
| Q34871440 | The immunological, environmental, and phylogenetic perpetrators of metastatic leishmaniasis. |
| Q37682484 | The immunology of fibrosis: innate and adaptive responses |
| Q84612714 | The importance of biologicals in the treatment of SoJIA |
| Q91174157 | The inflammasome NLRP3 plays a dual role on mouse corpora cavernosa relaxation |
| Q35232670 | The inflammasome adaptor ASC contributes to multiple innate immune processes in the resolution of otitis media |
| Q38389302 | The inflammasome and IL-1β: implications for the treatment of inflammatory diseases. |
| Q38562425 | The inflammasome and danger molecule signaling: at the crossroads of inflammation and pathogen persistence in the oral cavity |
| Q39036848 | The inflammasome as a target for pain therapy |
| Q39619917 | The inflammasome component NLRP3 impairs antitumor vaccine by enhancing the accumulation of tumor-associated myeloid-derived suppressor cells |
| Q37982362 | The inflammasome in host defense. |
| Q24304087 | The inflammasomes |
| Q33748704 | The inflammasomes: mechanisms of activation and function |
| Q34329251 | The inhibition of mevalonate pathway induces upregulation of NALP3 expression: new insight in the pathogenesis of mevalonate kinase deficiency. |
| Q37896918 | The innate immune system in transplantation. |
| Q38062538 | The interplay between autophagy and ROS in tumorigenesis |
| Q35155012 | The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease |
| Q64086358 | The lncRNA Neat1 promotes activation of inflammasomes in macrophages |
| Q48193738 | The long pentraxin PTX3: A prototypical sensor of tissue injury and a regulator of homeostasis |
| Q38453147 | The mechanisms of action of vaccines containing aluminum adjuvants: an in vitro vs in vivo paradigm. |
| Q42713634 | The myeloid heat shock transcription factor 1/β-catenin axis regulates NLR family, pyrin domain-containing 3 inflammasome activation in mouse liver ischemia/reperfusion injury |
| Q27027790 | The neutrophil in antineutrophil cytoplasmic autoantibody-associated vasculitis |
| Q42265456 | The nucleotide-binding domain and leucine-rich repeat protein-3 inflammasome is not activated in airway smooth muscle upon toll-like receptor-2 ligation. |
| Q42559247 | The peptide toxin amylosin of Bacillus amyloliquefaciens from moisture-damaged buildings is immunotoxic, induces potassium efflux from mammalian cells, and has antimicrobial activity |
| Q28085212 | The permissive role of glucocorticoids in neuroinflammatory priming: mechanisms and insights |
| Q92604093 | The regenerative potential of skin and the immune system |
| Q35752267 | The return of metabolism: biochemistry and physiology of the pentose phosphate pathway |
| Q37683553 | The role IL-1 in tumor-mediated angiogenesis |
| Q33820331 | The role of NLRP3 inflammasome in 5-fluorouracil resistance of oral squamous cell carcinoma |
| Q37690949 | The role of NOD-like Receptors in shaping adaptive immunity. |
| Q89928658 | The role of annexin A1 in the modulation of the NLRP3 inflammasome |
| Q41218452 | The role of bacteria and pattern recognition receptors in GVHD |
| Q38074434 | The role of gut-liver axis in the pathogenesis of liver cirrhosis and portal hypertension |
| Q26996822 | The role of inflammasome in Alzheimer's disease |
| Q38056731 | The role of innate immune signals in immunity to Brucella abortus |
| Q37855697 | The role of innate immunity in donor organ procurement |
| Q93206516 | The role of innate immunity in mucopolysaccharide diseases |
| Q27860900 | The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors |
| Q30494136 | The role of potassium in inflammasome activation by bacteria |
| Q37768045 | The role of the inflammasome in nonmyeloid cells |
| Q92875049 | The role of the innate immune system in allergic contact dermatitis |
| Q38367696 | The role of the mediators of inflammation in cancer development. |
| Q37784863 | The roles of TNF in brain dysfunction and disease |
| Q24337667 | The sedoheptulose kinase CARKL directs macrophage polarization through control of glucose metabolism |
| Q35373060 | The sterile inflammation in the exacerbation of HBV-associated liver injury |
| Q37716003 | The sterile inflammatory response |
| Q28539757 | The structural pathway of interleukin 1 (IL-1) initiated signaling reveals mechanisms of oncogenic mutations and SNPs in inflammation and cancer |
| Q42233804 | The teleost acute-phase inflammatory response and caspase activation by a novel alarmin-like ligand |
| Q39271545 | Therapeutic Strategies Under Development Targeting Inflammatory Mechanisms in Amyotrophic Lateral Sclerosis |
| Q50233845 | Therapeutic approaches targeting inflammation for diabetes and associated cardiovascular risk. |
| Q33651739 | Therapeutic effect of Schistosoma japonicum cystatin on bacterial sepsis in mice |
| Q35868028 | Therapy of autoinflammatory syndromes |
| Q29614471 | Thioredoxin-interacting protein links oxidative stress to inflammasome activation |
| Q38050454 | Thymosin β4 and cardiac protection: implication in inflammation and fibrosis |
| Q38644037 | Tick-Borne Viruses and Biological Processes at the Tick-Host-Virus Interface |
| Q37322741 | Ticks and tick-borne pathogens at the cutaneous interface: host defenses, tick countermeasures, and a suitable environment for pathogen establishment |
| Q51018682 | Tissue-based class control: the other side of tolerance. |
| Q37820049 | To be or not to be a pathogen: that is the mucosally relevant question |
| Q30418305 | To forge a solid immune recognition |
| Q36058919 | Toll-like receptor (TLR) and inflammasome actions in the central nervous system |
| Q36322359 | Toll-like receptor 4-interacting SPA4 peptide suppresses the NLRP3 inflammasome in response to LPS and ATP stimuli |
| Q37616217 | Toll-like receptors and NOD-like receptors in rheumatic diseases |
| Q37036694 | Toward understanding the mechanism underlying the strong adjuvant activity of aluminum salt nanoparticles |
| Q52659646 | Tranilast directly targets NLRP3 to treat inflammasome-driven diseases. |
| Q92802198 | Transcriptional analysis of THP-1 cells infected with Leishmania infantum indicates no activation of the inflammasome platform |
| Q34626353 | Transcriptional analysis of the three Nlrp1 paralogs in mice |
| Q27310102 | Transcriptome markers of viral persistence in naturally-infected andes virus (bunyaviridae) seropositive long-tailed pygmy rice rats |
| Q36816872 | Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases |
| Q37636664 | Treating inflammation by blocking interleukin-1 in humans |
| Q26799747 | Treating rheumatological diseases and co-morbidities with interleukin-1 blocking therapies |
| Q38365710 | Treatment of hyperimmunoglobulinemia D syndrome with biologics in children: review of the literature and Finnish experience |
| Q45072779 | Trimethylamine-N-Oxide Instigates NLRP3 Inflammasome Activation and Endothelial Dysfunction |
| Q54433700 | Two SNPs in NLRP3 gene are involved in the predisposition to type-1 diabetes and celiac disease in a pediatric population from northeast Brazil. |
| Q38004932 | Type I IFN-mediated regulation of IL-1 production in inflammatory disorders. |
| Q44492801 | Type I NKT-cell-mediated TNF-α is a positive regulator of NLRP3 inflammasome priming. |
| Q36220759 | Tyrosine phosphatase inhibition induces an ASC-dependent pyroptosis |
| Q26751376 | Ubiquitin signaling in immune responses |
| Q28550483 | Ultradeformable Archaeosomes for Needle Free Nanovaccination with Leishmania braziliensis Antigens |
| Q42504727 | Ultraviolet Radiation-Induced Downregulation of SERCA2 Mediates Activation of NLRP3 Inflammasome in Basal Cell Carcinoma |
| Q34224580 | Unbiased identification of target antigens of CD8+ T cells with combinatorial libraries coding for short peptides |
| Q89967655 | Understanding Inflammatory Responses in the Manifestation of Prothrombotic Phenotypes |
| Q64961502 | Understanding the Role of Innate Immunity in the Response to Intracortical Microelectrodes. |
| Q55312741 | Unique Action of Interleukin-18 on T Cells and Other Immune Cells. |
| Q41943672 | Unique Versus Redundant Functions of IL-1α and IL-1β in the Tumor Microenvironment |
| Q36639213 | Unique and differential protein signatures within the mononuclear cells of HIV-1 and HCV mono-infected and co-infected patients |
| Q37176714 | Unsolved Mysteries in NLR Biology |
| Q37420844 | Up-regulation of mRNA ventricular PRNP prion protein gene expression in air pollution highly exposed young urbanites: endoplasmic reticulum stress, glucose regulated protein 78, and nanosized particles |
| Q27000320 | Update of immune events in the murine contact hypersensitivity model: toward the understanding of allergic contact dermatitis |
| Q37738119 | Update on biology: uric acid and the activation of immune and inflammatory cells |
| Q40474919 | Upregulation of NLRP3 inflammasome components in Mooren's ulcer. |
| Q34493996 | Urban air pollution produces up-regulation of myocardial inflammatory genes and dark chocolate provides cardioprotection |
| Q39956677 | Urban air pollution targets the dorsal vagal complex and dark chocolate offers neuroprotection. |
| Q50046250 | Uric acid and the vaccine adjuvant activity of aluminium (oxy)hydroxide nanoparticles. |
| Q26850727 | Uric acid, hyperuricemia and vascular diseases |
| Q37308070 | Use of anti-cancer drugs, mitocans, to enhance the immune responses against tumors. |
| Q36168232 | Vaccine adjuvants: putting innate immunity to work |
| Q36835632 | Vaccinia virus F1L protein promotes virulence by inhibiting inflammasome activation |
| Q34979025 | Varicella-zoster virus infection triggers formation of an interleukin-1β (IL-1β)-processing inflammasome complex |
| Q47549703 | Verdinexor Targeting of CRM1 is a Promising Therapeutic Approach against RSV and Influenza Viruses |
| Q90198276 | Viroporins and inflammasomes: A key to understand virus-induced inflammation |
| Q111086228 | Viroporins: structure, function, and their role in the life cycle of SARS-CoV-2 |
| Q35260293 | Virus infection recognition and early innate responses to non-enveloped viral vectors |
| Q92000902 | Walking over the inflammasome |
| Q34420031 | When less is more: primary immunodeficiency with an autoinflammatory kick |
| Q28387356 | Why does the hemolytic activity of silica predict its pro-inflammatory activity? |
| Q38224492 | Wound healing reaction: A switch from gestation to senescence |
| Q47192369 | Yupingfeng San Inhibits NLRP3 Inflammasome to Attenuate the Inflammatory Response in Asthma Mice |
| Q56342324 | Zika virus elicits inflammation to evade antiviral response by cleaving cGAS via NS1-caspase-1 axis |
| Q47215672 | Zika virus infection induces host inflammatory responses by facilitating NLRP3 inflammasome assembly and interleukin-1β secretion |
| Q52887889 | [Comments on the pathogenesis of Behçet's disease. A key to understanding new therapies?]. |
| Q89068270 | [Intervention with Schistosoma japonicum cysteine protease inhibitor for treatment of lipopolysaccharide-induced sepsis in mice] |
| Q34023192 | iGLuc: a luciferase-based inflammasome and protease activity reporter |
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