| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1014275197 |
| P356 | DOI | 10.1038/10049 |
| P3181 | OpenCitations bibliographic resource ID | 1497716 |
| P698 | PubMed publication ID | 10559878 |
| P5875 | ResearchGate publication ID | 12741045 |
| P2093 | author name string | Pines J | |
| Clute P | |||
| P2860 | cites work | CDC27Hs colocalizes with CDC16Hs to the centrosome and mitotic spindle and is essential for the metaphase to anaphase transition | Q24316218 |
| Destruction of the CDC28/CLB mitotic kinase is not required for the metaphase to anaphase transition in budding yeast | Q24564643 | ||
| The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation | Q24601346 | ||
| MAD2 associates with the cyclosome/anaphase-promoting complex and inhibits its activity | Q24648493 | ||
| The checkpoint delaying anaphase in response to chromosome monoorientation is mediated by an inhibitory signal produced by unattached kinetochores | Q24651512 | ||
| The cyclosome, a large complex containing cyclin-selective ubiquitin ligase activity, targets cyclins for destruction at the end of mitosis | Q24656114 | ||
| The Schizosaccharomyces pombe spindle checkpoint protein mad2p blocks anaphase and genetically interacts with the anaphase-promoting complex | Q24683919 | ||
| Control of cyclin ubiquitination by CDK-regulated binding of Hct1 to the anaphase promoting complex | Q27933305 | ||
| An ESP1/PDS1 complex regulates loss of sister chromatid cohesion at the metaphase to anaphase transition in yeast | Q27938525 | ||
| Cyclin is degraded by the ubiquitin pathway | Q28131704 | ||
| Isolation of a human cyclin cDNA: evidence for cyclin mRNA and protein regulation in the cell cycle and for interaction with p34cdc2 | Q28257603 | ||
| How proteolysis drives the cell cycle | Q28297983 | ||
| Human cyclins A and B1 are differentially located in the cell and undergo cell cycle-dependent nuclear transport | Q28612313 | ||
| Control of cyclin B1 localization through regulated binding of the nuclear export factor CRM1 | Q28613275 | ||
| Cell cycle checkpoints: preventing an identity crisis | Q29547644 | ||
| Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC-dependent degradation of the anaphase inhibitor Pds1p | Q29615276 | ||
| A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B | Q29620071 | ||
| Localization of Mad2 to kinetochores depends on microtubule attachment, not tension | Q29620330 | ||
| Microinjection of antibody to Mad2 protein into mammalian cells in mitosis induces premature anaphase | Q30442107 | ||
| Differential expression of a phosphoepitope at the kinetochores of moving chromosomes | Q30464717 | ||
| Cell cycle checkpoints: arresting progress in mitosis | Q30470283 | ||
| Cyclin B2 undergoes cell cycle-dependent nuclear translocation and, when expressed as a non-destructible mutant, causes mitotic arrest in HeLa cells. | Q31107812 | ||
| The disappearance of cyclin B at the end of mitosis is regulated spatially in Drosophila cells | Q33890771 | ||
| The A- and B-type cyclin associated cdc2 kinases in Xenopus turn on and off at different times in the cell cycle. | Q33921443 | ||
| A subunit of the anaphase-promoting complex is a centromere-associated protein in mammalian cells | Q33997177 | ||
| Anaphase is initiated by proteolysis rather than by the inactivation of maturation-promoting factor. | Q34729839 | ||
| Cut2 proteolysis required for sister-chromatid seperation in fission yeast | Q34733084 | ||
| Anaphase onset in vertebrate somatic cells is controlled by a checkpoint that monitors sister kinetochore attachment to the spindle | Q36234928 | ||
| The requirements for protein synthesis and degradation, and the control of destruction of cyclins A and B in the meiotic and mitotic cell cycles of the clam embryo | Q36530877 | ||
| Mitosis in vertebrate somatic cells with two spindles: implications for the metaphase/anaphase transition checkpoint and cleavage | Q36765631 | ||
| Imaging green fluorescent protein fusion proteins in Saccharomyces cerevisiae. | Q36880918 | ||
| Mutagenic analysis of the destruction signal of mitotic cyclins and structural characterization of ubiquitinated intermediates | Q37382258 | ||
| Fission yeast Slp1: an effector of the Mad2-dependent spindle checkpoint | Q39450461 | ||
| Destruction of Xenopus cyclins A and B2, but not B1, requires binding to p34cdc2. | Q40790755 | ||
| The spindle assembly checkpoint | Q41239083 | ||
| Nuclear export of cyclin B1 and its possible role in the DNA damage-induced G2 checkpoint | Q41828411 | ||
| MPF localization is controlled by nuclear export | Q42649263 | ||
| The role of the destruction box and its neighbouring lysine residues in cyclin B for anaphase ubiquitin-dependent proteolysis in fission yeast: defining the D-box receptor | Q42655734 | ||
| Cyclin/Cdk-Dependent Initiation of DNA Replication in a Human Cell-Free System | Q58198972 | ||
| Mitotic arrest: Mad2 prevents sleepy from waking up the APC | Q74269541 | ||
| P433 | issue | 2 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 82-7 | |
| P577 | publication date | 1999-06-01 | |
| P1433 | published in | Nature Cell Biology | Q1574111 |
| P1476 | title | Temporal and spatial control of cyclin B1 destruction in metaphase | |
| P478 | volume | 1 |
| Q91960778 | A Chemical Screen Identifies Compounds Capable of Selecting for Haploidy in Mammalian Cells |
| Q42169114 | A cdk1 gradient guides surface contraction waves in oocytes. |
| Q38932588 | A chromosome separation checkpoint: A midzone Aurora B gradient mediates a chromosome separation checkpoint that regulates the anaphase-telophase transition. |
| Q42084036 | A map of protein dynamics during cell-cycle progression and cell-cycle exit. |
| Q34956519 | A novel DAG-dependent mechanism links PKCɑ and Cyclin B1 regulating cell cycle progression |
| Q37710823 | A novel direct activator of AMPK inhibits prostate cancer growth by blocking lipogenesis |
| Q33911201 | A novel synthetic 1,3-phenyl bis-thiourea compound targets microtubule polymerization to cause cancer cell death |
| Q42175728 | A proteomic study of mitotic phase-specific interactors of EB1 reveals a role for SXIP-mediated protein interactions in anaphase onset. |
| Q37293039 | A quantitative systems view of the spindle assembly checkpoint |
| Q43106462 | A role for Chk1 in blocking transcriptional elongation of p21 RNA during the S-phase checkpoint |
| Q34085727 | A single bivalent efficiently inhibits cyclin B1 degradation and polar body extrusion in mouse oocytes indicating robust SAC during female meiosis I. |
| Q92025168 | A tumor-specific modulation of heterogeneous ribonucleoprotein A0 promotes excessive mitosis and growth in colorectal cancer cells |
| Q28366341 | APC/C-mediated destruction of the centrosomal kinase Nek2A occurs in early mitosis and depends upon a cyclin A-type D-box |
| Q24338143 | APC15 drives the turnover of MCC-CDC20 to make the spindle assembly checkpoint responsive to kinetochore attachment |
| Q40370214 | APC16 is a conserved subunit of the anaphase-promoting complex/cyclosome |
| Q24651964 | APCcdh1 activity in mouse oocytes prevents entry into the first meiotic division |
| Q33799210 | Activation of cyclin B1-Cdk1 synchronizes events in the nucleus and the cytoplasm at mitosis |
| Q24338617 | Active cyclin B1-Cdk1 first appears on centrosomes in prophase |
| Q39834578 | Adenovirally mediated p53 overexpression diversely influence the cell cycle of HEp-2 and CAL 27 cell lines upon cisplatin and methotrexate treatment. |
| Q28487763 | Amitozyn impairs chromosome segregation and induces apoptosis via mitotic checkpoint activation |
| Q28483300 | An antitubulin agent BCFMT inhibits proliferation of cancer cells and induces cell death by inhibiting microtubule dynamics |
| Q48268399 | An interaction between myosin-10 and the cell cycle regulator Wee1 links spindle dynamics to mitotic progression in epithelia |
| Q58700295 | Analysis of the role of GSK3 in the mitotic checkpoint |
| Q41229624 | Anaphase-promoting complex/cyclosome participates in the acute response to protein-damaging stress |
| Q39022250 | Aneuploidy in Cancer and Aging |
| Q64106924 | Aneuploidy in Oocytes Is Prevented by Sustained CDK1 Activity through Degron Masking in Cyclin B1 |
| Q34014334 | Antagonists of anaphase-promoting complex (APC)-2-cell cycle and apoptosis regulatory protein (CARP)-1 interaction are novel regulators of cell growth and apoptosis |
| Q41671699 | Aurora B and cyclin B have opposite effects on the timing of cytokinesis abscission in Drosophila germ cells and in vertebrate somatic cells |
| Q39540799 | Aurora B potentiates Mps1 activation to ensure rapid checkpoint establishment at the onset of mitosis. |
| Q42238706 | Basis of catalytic assembly of the mitotic checkpoint complex |
| Q45968556 | Bleomycin-induced over-replication involves sustained inhibition of mitotic entry through the ATM/ATR pathway. |
| Q28508711 | Brd4 is required for recovery from antimicrotubule drug-induced mitotic arrest: preservation of acetylated chromatin |
| Q42575503 | BubR1 N terminus acts as a soluble inhibitor of cyclin B degradation by APC/C(Cdc20) in interphase |
| Q38975034 | Building a Regulatory Network with Short Linear Sequence Motifs: Lessons from the Degrons of the Anaphase-Promoting Complex. |
| Q43126373 | C-terminal domain phosphorylation of ERK3 controlled by Cdk1 and Cdc14 regulates its stability in mitosis |
| Q40030976 | CDK1 structures reveal conserved and unique features of the essential cell cycle CDK. |
| Q64295741 | CDK1-CCNB1 creates a spindle checkpoint-permissive state by enabling MPS1 kinetochore localization |
| Q42521258 | Ca(2+) oscillations promote APC/C-dependent cyclin B1 degradation during metaphase arrest and completion of meiosis in fertilizing mouse eggs. |
| Q47774194 | Ca(2+)-promoted cyclin B1 degradation in mouse oocytes requires the establishment of a metaphase arrest |
| Q39755325 | Cdc20 is required for the post-anaphase, KEN-dependent degradation of centromere protein F. |
| Q35619339 | Cdh1 regulates osteoblast function through an APC/C-independent modulation of Smurf1. |
| Q37671387 | Cdk1 inactivation terminates mitotic checkpoint surveillance and stabilizes kinetochore attachments in anaphase |
| Q30656511 | Cdk1 phosphorylates the Rac activator Tiam1 to activate centrosomal Pak and promote mitotic spindle formation. |
| Q40243297 | Cdk1 phosphorylation sites on Cdc27 are required for correct chromosomal localisation and APC/C function in syncytial Drosophila embryos |
| Q28611400 | Cdk1, Plks, Auroras, and Neks: the mitotic bodyguards |
| Q35534947 | Cdk1-mediated phosphorylation of human ATF7 at Thr-51 and Thr-53 promotes cell-cycle progression into M phase |
| Q58057607 | Cell adhesion is regulated by CDK1 during the cell cycle |
| Q27014767 | Cell cycle regulators guide mitochondrial activity in radiation-induced adaptive response |
| Q38915258 | Cell cycle staging of individual cells by fluorescence microscopy. |
| Q24600785 | Cell cycle- and cell growth-regulated proteolysis of mammalian CDC6 is dependent on APC-CDH1 |
| Q33411388 | Cell type specific applicability of 5-ethynyl-2'-deoxyuridine (EdU) for dynamic proliferation assessment in flow cytometry |
| Q33963387 | Cell-cycle responses to DNA damage in G2. |
| Q45067861 | Cell-cycle transitions: a common role for stoichiometric inhibitors. |
| Q37342483 | Cells satisfy the mitotic checkpoint in Taxol, and do so faster in concentrations that stabilize syntelic attachments |
| Q30662520 | Centrosomes enhance the fidelity of cytokinesis in vertebrates and are required for cell cycle progression |
| Q34645278 | Changes in the localization of the Saccharomyces cerevisiae anaphase-promoting complex upon microtubule depolymerization and spindle checkpoint activation |
| Q24304920 | Characterization and expression of mammalian cyclin b3, a prepachytene meiotic cyclin |
| Q40799759 | Characterization of an N-terminally truncated cyclin A isoform in mammalian cells. |
| Q37459418 | Characterization of mitosis-specific phosphorylation of tumor-associated microtubule-associated protein |
| Q34282259 | Checking out the G(2)/M transition. |
| Q39446342 | Choosing Cell Fate Through a Dynamic Cell Cycle |
| Q47696921 | Chromosome biorientation and APC activity remain uncoupled in oocytes with reduced volume. |
| Q28588417 | Chromosome missegregation and apoptosis in mice lacking the mitotic checkpoint protein Mad2 |
| Q36376462 | Chromosome movement in mitosis requires microtubule anchorage at spindle poles |
| Q24319757 | Chronophin, a novel HAD-type serine protein phosphatase, regulates cofilin-dependent actin dynamics |
| Q28571169 | Citron kinase is a cell cycle-dependent, nuclear protein required for G2/M transition of hepatocytes |
| Q36836276 | Classic "broken cell" techniques and newer live cell methods for cell cycle assessment |
| Q39172440 | Clusterin knockdown sensitizes prostate cancer cells to taxane by modulating mitosis. |
| Q42944697 | Co-activator independent differences in how the metaphase and anaphase APC/C recognise the same substrate. |
| Q37707482 | Co-regulation proteomics reveals substrates and mechanisms of APC/C-dependent degradation |
| Q34473920 | Cohesion fatigue explains why pharmacological inhibition of the APC/C induces a spindle checkpoint-dependent mitotic arrest |
| Q34040427 | Conditional targeting of MAD1 to kinetochores is sufficient to reactivate the spindle assembly checkpoint in metaphase |
| Q38025305 | Connecting up and clearing out: how kinetochore attachment silences the spindle assembly checkpoint. |
| Q33952284 | Control of centrin stability by Aurora A. |
| Q28611955 | Control of mitosis by changes in the subcellular location of cyclin-B1-Cdk1 and Cdc25C |
| Q36288907 | Control of mitotic exit by PP2A regulation of Cdc25C and Cdk1. |
| Q44226599 | Cooperative phosphorylation including the activity of polo-like kinase 1 regulates the subcellular localization of cyclin B1. |
| Q38298213 | Cre recombinase induces DNA damage and tetraploidy in the absence of loxP sites |
| Q48529643 | Cubism and the cell cycle: the many faces of the APC/C. |
| Q24683942 | Cyclin A is destroyed in prometaphase and can delay chromosome alignment and anaphase |
| Q44632612 | Cyclin A2 is phosphorylated during the G2/M transition in mouse two‐cell embryos |
| Q53538160 | Cyclin B1 is commonly expressed in the cytoplasm of primary human acute myelogenous leukemia cells and serves as a leukemia-associated antigen associated with autoantibody response in a subset of patients. |
| Q24306556 | Cyclin B1 is localized to unattached kinetochores and contributes to efficient microtubule attachment and proper chromosome alignment during mitosis |
| Q35442206 | Cyclin B1 overexpression induces cell death independent of mitotic arrest |
| Q64900442 | Cyclin B2 can compensate for Cyclin B1 in oocyte meiosis I. |
| Q24599817 | Cyclin F regulates the nuclear localization of cyclin B1 through a cyclin-cyclin interaction |
| Q35013072 | Cyclin destruction in mitosis: a crucial task of Cdc20. |
| Q34075028 | Cyclin-dependent kinase inhibitors: novel anticancer agents |
| Q80510509 | Cyclin-dependent kinases as targets for cancer therapy |
| Q81086253 | Cyclin-dependent kinases as targets for cancer therapy |
| Q35679855 | Cytometry of the cell cycle: cycling through history |
| Q33911093 | Cytoplasmic dynein's mitotic spindle pole localization requires a functional anaphase-promoting complex, gamma-tubulin, and NUDF/LIS1 in Aspergillus nidulans |
| Q24316471 | D53 (TPD52L1) is a cell cycle-regulated protein maximally expressed at the G2-M transition in breast cancer cells |
| Q47111336 | DNA damage induces a kinetochore-based ATM/ATR-independent SAC arrest unique to the first meiotic division in mouse oocytes |
| Q41082765 | DT-13 synergistically enhanced vinorelbine-mediated mitotic arrest through inhibition of FOXM1-BICD2 axis in non-small-cell lung cancer cells |
| Q38663796 | De novo fatty acid synthesis at the mitotic exit is required to complete cellular division |
| Q38178223 | Deciphering the spatio-temporal regulation of entry and progression through mitosis |
| Q30667509 | Defective sister chromatid cohesion is synthetically lethal with impaired APC/C function. |
| Q34733424 | Defects in G1-S cell cycle control in head and neck cancer: a review |
| Q41550121 | Delayed APC/C activation extends the first mitosis of mouse embryos |
| Q41997479 | Deoxyribonucleotide metabolism in cycling and resting human fibroblasts with a missense mutation in p53R2, a subunit of ribonucleotide reductase |
| Q28207995 | Deregulated human Cdc14A phosphatase disrupts centrosome separation and chromosome segregation |
| Q34626099 | Determinants of human cyclin B1 association with mitotic chromosomes |
| Q33306110 | Developmental role and regulation of cortex, a meiosis-specific anaphase-promoting complex/cyclosome activator |
| Q41872421 | Different types of cell cycle- and apoptosis-related gene expressions alter in corticosteroid-, vincristine-, and melphalan-resistant u-266 multiple myeloma cell lines |
| Q24530195 | Differential expression, localization and activity of two alternatively spliced isoforms of human APC regulator CDH1 |
| Q53544045 | Differential mitotic degradation of the CDC25B phosphatase variants. |
| Q30480758 | Distinct sequence elements of cyclin B1 promote localization to chromatin, centrosomes, and kinetochores during mitosis |
| Q60046403 | Divergent impact of actin isoforms on cell cycle regulation |
| Q30477570 | Dose-dependent effects of stable cyclin B1 on progression through mitosis in human cells |
| Q37625057 | Double duty for nuclear proteins--the price of more open forms of mitosis |
| Q27304870 | Dual control by Cdk1 phosphorylation of the budding yeast APC/C ubiquitin ligase activator Cdh1 |
| Q48873086 | Dual inhibition of sister chromatid separation at metaphase |
| Q28386155 | Dual mode of degradation of Cdc25 A phosphatase |
| Q37721752 | Dual-mode regulation of the APC/C by CDK1 and MAPK controls meiosis I progression and fidelity |
| Q30359502 | Dynamic Phosphorylation of NudC by Aurora B in Cytokinesis |
| Q40207573 | Dynamic green fluorescent protein sensors for high-content analysis of the cell cycle |
| Q28345518 | Dynamic recruitment of Cdc2 to specific microtubule structures during mitosis |
| Q24521352 | Dynamic recruitment of Nek2 kinase to the centrosome involves microtubules, PCM-1, and localized proteasomal degradation. |
| Q50877102 | Dynamics of ubiquitin-mediated signalling: insights from mathematical modelling and experimental studies. |
| Q24312788 | Dynein light intermediate chain 1 is required for progress through the spindle assembly checkpoint |
| Q27437627 | Dynein/Dynactin-mediated transport of kinetochore components off kinetochores and onto spindle poles induced by nordihydroguaiaretic acid |
| Q24322917 | Early mitotic degradation of Nek2A depends on Cdc20-independent interaction with the APC/C |
| Q24681647 | Early mitotic degradation of the homeoprotein HOXC10 is potentially linked to cell cycle progression |
| Q35120100 | Effect of demecolcine-assisted enucleation on the MPF level and cyclin B1 distribution in porcine oocytes |
| Q36336999 | Efficient APC/C substrate degradation in cells undergoing mitotic exit depends on K11 ubiquitin linkages |
| Q28199187 | Emi1 is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex |
| Q30480589 | Emi1 is needed to couple DNA replication with mitosis but does not regulate activation of the mitotic APC/C |
| Q81304007 | Enhanced matrix degradation after withdrawal of TGF-beta1 triggers hepatocytes from apoptosis to proliferation and regeneration |
| Q43968083 | Evidence for a pre-restriction point Cdk3 activity |
| Q42128896 | Evidence that mitotic exit is a better cancer therapeutic target than spindle assembly. |
| Q52903614 | Expression and Clinical Role of Cdc5L as a Novel Cell Cycle Protein in Hepatocellular Carcinoma. |
| Q24338161 | Fcp1-dependent dephosphorylation is required for M-phase-promoting factor inactivation at mitosis exit |
| Q36636175 | Feedback regulation between atypical E2Fs and APC/CCdh1 coordinates cell cycle progression |
| Q58793764 | Fenbendazole acts as a moderate microtubule destabilizing agent and causes cancer cell death by modulating multiple cellular pathways |
| Q44970229 | Fertilization and InsP3-induced Ca2+ release stimulate a persistent increase in the rate of degradation of cyclin B1 specifically in mature mouse oocytes |
| Q24299543 | Fez1/Lzts1 absence impairs Cdk1/Cdc25C interaction during mitosis and predisposes mice to cancer development. |
| Q42936188 | Fiat Lux: illuminating the cell cycle. |
| Q30439662 | Fine tuning the cell cycle: activation of the Cdk1 inhibitory phosphorylation pathway during mitotic exit |
| Q47072481 | Flies without a spindle checkpoint |
| Q53578573 | Flow cytometry to sort mammalian cells in cytokinesis. |
| Q42910791 | Forkhead transcription factor FoxM1 regulates mitotic entry and prevents spindle defects in cerebellar granule neuron precursors. |
| Q33772655 | Four-dimensional control of the cell cycle |
| Q26998944 | Functional characterization of Anaphase Promoting Complex/Cyclosome (APC/C) E3 ubiquitin ligases in tumorigenesis |
| Q24683190 | Functional importance of the anaphase-promoting complex-Cdh1-mediated degradation of TMAP/CKAP2 in regulation of spindle function and cytokinesis |
| Q30480028 | GEF-H1 modulates localized RhoA activation during cytokinesis under the control of mitotic kinases |
| Q34048293 | HER4 D-box sequences regulate mitotic progression and degradation of the nuclear HER4 cleavage product s80HER4. |
| Q33613221 | HIV-1 Tat regulates cyclin B1 by promoting both expression and degradation |
| Q27488266 | Hepatitis C Virus NS5A Protein Down-regulates the Expression of Spindle Gene Aspm through PKR-p38 Signaling Pathway |
| Q24304133 | Hip2 interacts with cyclin B1 and promotes its degradation through the ubiquitin proteasome pathway |
| Q42699227 | How APC/C-Cdc20 changes its substrate specificity in mitosis |
| Q34083210 | How cyclin A destruction escapes the spindle assembly checkpoint |
| Q21203559 | How eggs arrest at metaphase II: MPF stabilisation plus APC/C inhibition equals Cytostatic Factor |
| Q24536263 | Human Mps1 kinase is required for the spindle assembly checkpoint but not for centrosome duplication |
| Q42918706 | Human cyclin A is required for mitosis until mid prophase |
| Q41316394 | Human kinetochores are swivel joints that mediate microtubule attachments. |
| Q39698930 | Human replication protein Cdc6 prevents mitosis through a checkpoint mechanism that implicates Chk1. |
| Q40724282 | Human securin proteolysis is controlled by the spindle checkpoint and reveals when the APC/C switches from activation by Cdc20 to Cdh1. |
| Q33899518 | Identification of CIP-1-associated regulator of cyclin B (CARB), a novel p21-binding protein acting in the G2 phase of the cell cycle |
| Q57887391 | Identification of Cell Cycle‐Dependent Phosphorylation Sites on the Anaphase‐Promoting Complex/Cyclosome by Mass Spectrometry |
| Q24299394 | Identification of a novel brain-specific and Reelin-regulated gene that encodes a protein colocalized with synapsin |
| Q52740508 | Inducing "cytokinesis" without mitosis in unfertilized Drosophila eggs. |
| Q34733119 | Inducing precocious anaphase in cultured mammalian cells |
| Q30621924 | Insights into the cellular mechanism of the yeast ubiquitin ligase APC/C-Cdh1 from the analysis of in vivo degrons |
| Q41035104 | Insulin-like growth factor I regulates G2/M progression through mammalian target of rapamycin signaling in oligodendrocyte progenitors. |
| Q27324227 | Interphase APC/C-Cdc20 inhibition by cyclin A2-Cdk2 ensures efficient mitotic entry |
| Q92421651 | Interplay between Phosphatases and the Anaphase-Promoting Complex/Cyclosome in Mitosis |
| Q24322804 | Involvement of SIRT7 in resumption of rDNA transcription at the exit from mitosis |
| Q37033808 | Is the time dimension of the cell cycle re-entry in AD regulated by centromere cohesion dynamics? |
| Q36710812 | JunB breakdown in mid-/late G2 is required for down-regulation of cyclin A2 levels and proper mitosis |
| Q37106715 | Kinetochore stretching inactivates the spindle assembly checkpoint |
| Q92727428 | Lack of Cyclin B1 in zebrafish causes lengthening of G2 and M phases |
| Q36235524 | Lack of response to unaligned chromosomes in mammalian female gametes |
| Q48703968 | Large-scale purification of the vertebrate anaphase-promoting complex/cyclosome |
| Q33942360 | Late mitotic failure in mice lacking Sak, a polo-like kinase. |
| Q38214413 | Less understood issues: p21(Cip1) in mitosis and its therapeutic potential. |
| Q42564429 | Linking cell division to cell growth in a spatiotemporal model of the cell cycle |
| Q31122048 | Localization of gamma-tubulin and cyclin B during early cleavage in physiologically polyspermic newt eggs |
| Q111442281 | Low Cell Number Proteomic Analysis Using In-Cell Protease Digests Reveals a Robust Signature for Cell Cycle State Classification |
| Q64936442 | M2I-1 disrupts the in vivo interaction between CDC20 and MAD2 and increases the sensitivities of cancer cell lines to anti-mitotic drugs via MCL-1s. |
| Q33496461 | MT7, a novel compound from a combinatorial library, arrests mitosis via inhibiting the polymerization of microtubules |
| Q33763645 | Mad2 prevents aneuploidy and premature proteolysis of cyclin B and securin during meiosis I in mouse oocytes |
| Q36879638 | Making an effective switch at the kinetochore by phosphorylation and dephosphorylation |
| Q93160968 | Mammalian kinetochores count attached microtubules in a sensitive and switch-like manner |
| Q38026773 | Maturation of the kinetochore-microtubule interface and the meaning of metaphase. |
| Q30514185 | Mechanical impulses can control metaphase progression in a mammalian cell |
| Q33836931 | Mechanism of Aurora-B degradation and its dependency on intact KEN and A-boxes: identification of an aneuploidy-promoting property |
| Q27303672 | Mechanism of cancer cell death induced by depletion of an essential replication regulator |
| Q24307635 | Mechanisms controlling the temporal degradation of Nek2A and Kif18A by the APC/C-Cdc20 complex |
| Q47614531 | Medicinal Attributes of Thienopyrimidine Based Scaffold Targeting Tyrosine Kinases and Their Potential Anticancer Activities. |
| Q36339146 | Methods to measure ubiquitin-dependent proteolysis mediated by the anaphase-promoting complex. |
| Q74340087 | Microtubule disassembly delays the G2-M transition in vertebrates |
| Q24555706 | Microtubule-dependent changes in assembly of microtubule motor proteins and mitotic spindle checkpoint proteins at PtK1 kinetochores |
| Q24642588 | Microtubules do not promote mitotic slippage when the spindle assembly checkpoint cannot be satisfied |
| Q52321991 | Mitotic Exit dysfunction through the deregulation of APC/C characterizes cisplatin resistant state in epithelial ovarian cancer. |
| Q42254103 | Mitotic Kinases and p53 Signaling |
| Q38961886 | Mitotic arrest and slippage induced by pharmacological inhibition of Polo-like kinase 1. |
| Q24648791 | Mitotic checkpoint slippage in humans occurs via cyclin B destruction in the presence of an active checkpoint |
| Q34132846 | Mitotic checkpoints: from yeast to cancer |
| Q30499682 | Mitotic progression becomes irreversible in prometaphase and collapses when Wee1 and Cdc25 are inhibited |
| Q24301075 | Mitotic regulation of the human anaphase-promoting complex by phosphorylation |
| Q30487023 | Mlp1 acts as a mitotic scaffold to spatially regulate spindle assembly checkpoint proteins in Aspergillus nidulans |
| Q35130703 | Modeling dual pathways for the metazoan spindle assembly checkpoint |
| Q37032329 | Molecular mechanisms creating bistable switches at cell cycle transitions. |
| Q39131699 | Mps1 kinase activity restrains anaphase during an unperturbed mitosis and targets Mad2 to kinetochores. |
| Q37894287 | Multi-scale modeling in biology: how to bridge the gaps between scales? |
| Q30591637 | Multiple mechanisms determine the order of APC/C substrate degradation in mitosis |
| Q36232665 | Mutant MyoD lacking Cdc2 phosphorylation sites delays M-phase entry |
| Q36527208 | Myt1 protein kinase is essential for Golgi and ER assembly during mitotic exit |
| Q34434372 | New insights into development from mitosis of a unicellular yeast |
| Q35576437 | New insights into the genetic regulation of homologue disjunction in mammalian oocytes. |
| Q33828711 | Novel microtubule-targeted agent 6-chloro-4-(methoxyphenyl) coumarin induces G2-M arrest and apoptosis in HeLa cells |
| Q24338466 | Nuclear pores protect genome integrity by assembling a premitotic and Mad1-dependent anaphase inhibitor |
| Q27937931 | Nuclear-specific degradation of Far1 is controlled by the localization of the F-box protein Cdc4. |
| Q36326406 | Nucleolar assembly of the rRNA processing machinery in living cells |
| Q33991847 | Nucleolus: from structure to dynamics |
| Q24679693 | Nucleolus: the fascinating nuclear body |
| Q30480911 | Oncogenic H-Ras V12 promotes anchorage-independent cytokinesis in human fibroblasts |
| Q36322375 | Ordered proteolysis in anaphase inactivates Plk1 to contribute to proper mitotic exit in human cells |
| Q38232313 | Organization of early frog embryos by chemical waves emanating from centrosomes. |
| Q37653615 | Overcoming inhibition in the spindle checkpoint |
| Q35011977 | Overexpression of the dynein light chain km23-1 in human ovarian carcinoma cells inhibits tumor formation in vivo and causes mitotic delay at prometaphase/metaphase |
| Q90171686 | Paradoxical mitotic exit induced by a small molecule inhibitor of APC/CCdc20 |
| Q42007577 | Persistence of DNA threads in human anaphase cells suggests late completion of sister chromatid decatenation |
| Q24303577 | Pharmacologic inhibition of the anaphase-promoting complex induces a spindle checkpoint-dependent mitotic arrest in the absence of spindle damage |
| Q37900486 | Phosphatases: providing safe passage through mitotic exit |
| Q53175734 | Pituitary tumor-transforming gene 1 enhances proliferation and suppresses early differentiation of keratinocytes. |
| Q30496569 | Polo kinase interacts with RacGAP50C and is required to localize the cytokinesis initiation complex. |
| Q38984499 | Polo-like kinase 1 regulates the stability of the mitotic centromere-associated kinesin in mitosis |
| Q34813724 | Pre-M phase-promoting factor associates with annulate lamellae in Xenopus oocytes and egg extracts |
| Q50452528 | Pre-anaphase chromosome oscillations are regulated by the antagonistic activities of Cdk1 and PP1 on Kif18A. |
| Q33810216 | Precocious centriole disengagement and centrosome fragmentation induced by mitotic delay |
| Q37863285 | Processive ubiquitin chain formation by the anaphase-promoting complex. |
| Q39711792 | Progressive activation of CyclinB1-Cdk1 coordinates entry to mitosis |
| Q36901528 | Prostate-specific membrane antigen associates with anaphase-promoting complex and induces chromosomal instability |
| Q43990578 | Proteasome dynamics during cell cycle in rat Schwann cells |
| Q38707201 | Proteasome inhibition enhances the efficacy of volasertib-induced mitotic arrest in AML in vitro and prolongs survival in vivo |
| Q33686351 | Protein Phosphatase 2A (PP2A) Regulates EG5 to Control Mitotic Progression |
| Q93183779 | Protein phosphatases in the regulation of mitosis |
| Q48550111 | Proteolysis: anytime, any place, anywhere? |
| Q35804599 | Proteomic Analysis of the Ubiquitin Landscape in the Drosophila Embryonic Nervous System and the Adult Photoreceptor Cells. |
| Q96958860 | Quantitative Imaging of B1 Cyclin Expression Across the Cell Cycle Using Green Fluorescent Protein Tagging and Epifluorescence |
| Q42915416 | Quantitative kinetic analysis of nucleolar breakdown and reassembly during mitosis in live human cells |
| Q35904350 | Quantitative proteomics reveals the basis for the biochemical specificity of the cell-cycle machinery |
| Q37930573 | Rat eggs cannot wait: Spontaneous exit from meiotic metaphase-II arrest |
| Q34354353 | Re-evaluating centrosome function |
| Q37181390 | Recombinant adenovirus of human p66Shc inhibits MCF-7 cell proliferation |
| Q34040203 | Recruitment of Mad1 to metaphase kinetochores is sufficient to reactivate the mitotic checkpoint. |
| Q29999767 | Recycling the Cell Cycle |
| Q35161978 | Regulated inactivation of the spindle assembly checkpoint without functional mitotic spindles |
| Q24683455 | Regulation of APC activity by phosphorylation and regulatory factors |
| Q92106577 | Regulation of Cell Cycle Entry and Exit: A Single Cell Perspective |
| Q28612074 | Regulation of G(2)/M events by Cdc25A through phosphorylation-dependent modulation of its stability |
| Q89719971 | Regulation of Mitotic Exit by Cell Cycle Checkpoints: Lessons From Saccharomyces cerevisiae |
| Q46240452 | Regulation of chromosome segregation in oocytes and the cellular basis for female meiotic errors |
| Q33772649 | Regulation of the APC and the exit from mitosis |
| Q28198064 | Regulation of the anaphase-promoting complex by the dual specificity phosphatase human Cdc14a |
| Q33816797 | Removal of Spindly from microtubule-attached kinetochores controls spindle checkpoint silencing in human cells |
| Q43628110 | Requirement of cyclin B2, but not cyclin B1, for bipolar spindle formation in frog (Rana japonica) oocytes. |
| Q38919400 | Responses of chromosome segregation machinery to mechanical perturbations |
| Q36732296 | Role for Cdk1 (Cdc2)/cyclin A in preventing the mammalian origin recognition complex's largest subunit (Orc1) from binding to chromatin during mitosis |
| Q33930496 | Rough deal and Zw10 are required for the metaphase checkpoint in Drosophila |
| Q46910564 | RyR channel-mediated increase of cytosolic free calcium level signals cyclin B1 degradation during abortive spontaneous egg activation in rat. |
| Q28475032 | S9, a novel anticancer agent, exerts its anti-proliferative activity by interfering with both PI3K-Akt-mTOR signaling and microtubule cytoskeleton |
| Q24545581 | Securin degradation is mediated by fzy and fzr, and is required for complete chromatid separation but not for cytokinesis |
| Q44229519 | Securin regulates entry into M-phase by modulating the stability of cyclin B. |
| Q30835754 | Separating centrosomes interact in the absence of associated chromosomes during mitosis in cultured vertebrate cells |
| Q24306351 | Shugoshin is a Mad1/Cdc20-like interactor of Mad2 |
| Q38258850 | Signalling dynamics in the spindle checkpoint response |
| Q36544267 | Skp1 in lung cancer: clinical significance and therapeutic efficacy of its small molecule inhibitors |
| Q28478936 | Small compound 6-O-angeloylplenolin induces mitotic arrest and exhibits therapeutic potentials in multiple myeloma |
| Q37552312 | Sorbus rufopilosa Extract Exhibits Antioxidant and Anticancer Activities by Inducing Cell Cycle Arrest and Apoptosis in Human Colon Adenocarcinoma HT29 Cells |
| Q34180443 | Spatial-temporal model for silencing of the mitotic spindle assembly checkpoint |
| Q83230151 | Spatiotemporal control of mitotic exit during anaphase by an aurora B-Cdk1 crosstalk |
| Q24546385 | Spatiotemporal control of spindle midzone formation by PRC1 in human cells |
| Q28081253 | Spatiotemporal regulation of the anaphase-promoting complex in mitosis |
| Q27318387 | Spindle assembly checkpoint inactivation fails to suppress neuroblast tumour formation in aurA mutant Drosophila. |
| Q35944756 | Spindle assembly checkpoint signalling is uncoupled from chromosomal position in mouse oocytes. |
| Q52717063 | Spindle assembly checkpoint strength is linked to cell fate in the C. elegans embryo. |
| Q37956287 | Spindle assembly checkpoint: the third decade |
| Q30431071 | Spindle poisons and cell fate: a tale of two pathways. |
| Q36074463 | Strain-specific spontaneous activation during mouse oocyte maturation |
| Q46259214 | Strong expression of cyclin B2 mRNA correlates with a poor prognosis in patients with non-small cell lung cancer |
| Q37956288 | Structural insights into anaphase-promoting complex function and mechanism |
| Q37811107 | Structure, function and mechanism of the anaphase promoting complex (APC/C) |
| Q40750476 | Study of the G2/M cell cycle checkpoint in irradiated mammary epithelial cells overexpressing Cul-4A gene |
| Q35186944 | Substrate degradation by the anaphase promoting complex occurs during mitotic slippage |
| Q52095924 | Substrate-dependent and organ-specific chloroplast protein import in planta. |
| Q33712149 | Sustained spindle-assembly checkpoint response requires de novo transcription and translation of cyclin B1. |
| Q41627572 | Synergistic inhibition of the APC/C by the removal of APC15 in HCT116 cells lacking UBE2C. |
| Q35049184 | System-level feedbacks make the anaphase switch irreversible |
| Q28115138 | TRAMM/TrappC12 plays a role in chromosome congression, kinetochore stability, and CENP-E recruitment |
| Q35688708 | Targeting Cdc20 as a novel cancer therapeutic strategy |
| Q27331477 | Targeting of Fzr/Cdh1 for timely activation of the APC/C at the centrosome during mitotic exit. |
| Q42008917 | The ABBA motif binds APC/C activators and is shared by APC/C substrates and regulators |
| Q31808529 | The APC is dispensable for first meiotic anaphase in Xenopus oocytes. |
| Q52118880 | The APC regulator CDH1 is essential for the progression of embryonic cell cycles in Xenopus. |
| Q24658244 | The APC/C maintains the spindle assembly checkpoint by targeting Cdc20 for destruction |
| Q28749570 | The APC/C recruits cyclin B1-Cdk1-Cks in prometaphase before D box recognition to control mitotic exit |
| Q92651169 | The Anaphase Promoting Complex/Cyclosome (APC/C): A Versatile E3 Ubiquitin Ligase |
| Q98178414 | The Error-Prone Kinetochore-Microtubule Attachments During Meiosis I in Vitrified Oocytes |
| Q52582189 | The Eukaryotic Nucleus, 9-13 September 1999, Coolfont Conference Center, Berkeley Springs, WV, USA. |
| Q90528409 | The G2-to-M Transition Is Ensured by a Dual Mechanism that Protects Cyclin B from Degradation by Cdc20-Activated APC/C |
| Q37025677 | The Genetic Program of Pancreatic β-Cell Replication In Vivo |
| Q44462834 | The MDM2 RING finger is required for cell cycle-dependent regulation of its protein expression. |
| Q39720335 | The Mitotic Checkpoint Complex Requires an Evolutionary Conserved Cassette to Bind and Inhibit Active APC/C. |
| Q27000712 | The Renaissance or the cuckoo clock |
| Q90736521 | The Role of Hydrogen Peroxide and Peroxiredoxins throughout the Cell Cycle |
| Q35868075 | The anaphase promoting complex/cyclosome is recruited to centromeres by the spindle assembly checkpoint. |
| Q29618398 | The anaphase promoting complex/cyclosome: a machine designed to destroy |
| Q36022931 | The anaphase-promoting complex: a key factor in the regulation of cell cycle |
| Q28610045 | The anaphase-promoting complex: proteolysis in mitosis and beyond |
| Q37194528 | The benefits of local depletion: The centrosome as a scaffold for ubiquitin-proteasome-mediated degradation |
| Q35164326 | The biochemistry of mitosis |
| Q90625848 | The coordination of nuclear envelope assembly and chromosome segregation in metazoans |
| Q42724508 | The cyclin B1 gene is actively transcribed during mitosis in HeLa cells. |
| Q33505663 | The human RNA polymerase II-associated factor 1 (hPaf1): a new regulator of cell-cycle progression |
| Q30835774 | The kinetochore-dependent and -independent formation of the CDC20-MAD2 complex and its functions in HeLa cells |
| Q28647358 | The localization of human cyclins B1 and B2 determines CDK1 substrate specificity and neither enzyme requires MEK to disassemble the Golgi apparatus |
| Q41832436 | The mitotic checkpoint complex binds a second CDC20 to inhibit active APC/C |
| Q37467150 | The nature of cell-cycle checkpoints: facts and fallacies |
| Q36533957 | The nucleolus: a model for the organization of nuclear functions |
| Q48886104 | The polo-like kinase Plx1 prevents premature inactivation of the APC(Fizzy)-dependent pathway in the early Xenopus cell cycle |
| Q30445825 | The reversibility of mitotic exit in vertebrate cells |
| Q36593086 | The role of modelling in identifying drug targets for diseases of the cell cycle |
| Q42917794 | The roles of Fzy/Cdc20 and Fzr/Cdh1 in regulating the destruction of cyclin B in space and time |
| Q24610068 | The roles of cyclin A2, B1, and B2 in early and late mitotic events |
| Q38700629 | The small molecule inhibitor YK-4-279 disrupts mitotic progression of neuroblastoma cells, overcomes drug resistance and synergizes with inhibitors of mitosis |
| Q37607534 | The spindle and kinetochore-associated (Ska) complex enhances binding of the anaphase-promoting complex/cyclosome (APC/C) to chromosomes and promotes mitotic exit |
| Q30557537 | The spindle assembly checkpoint works like a rheostat rather than a toggle switch |
| Q39138382 | The spindle checkpoint, APC/C(Cdc20), and APC/C(Cdh1) play distinct roles in connecting mitosis to S phase. |
| Q27860766 | The spindle-assembly checkpoint in space and time |
| Q34538530 | The traffic of proteins between nucleolar organizer regions and prenucleolar bodies governs the assembly of the nucleolus at exit of mitosis |
| Q34659420 | The transforming acidic coiled coil 3 protein is essential for spindle-dependent chromosome alignment and mitotic survival |
| Q37375173 | The ubiquitin ligase CRL2ZYG11 targets cyclin B1 for degradation in a conserved pathway that facilitates mitotic slippage. |
| Q38087182 | The ubiquitin proteasome system - implications for cell cycle control and the targeted treatment of cancer |
| Q24534348 | Timing of APC/C substrate degradation is determined by fzy/fzr specificity of destruction boxes |
| Q38845231 | Tracking the Cyclin B1-GFP Sensor to Profile the Pattern of Mitosis Versus Mitotic Bypass. |
| Q53216551 | Translationally controlled tumor protein induces mitotic defects and chromosome missegregation in hepatocellular carcinoma development. |
| Q28392478 | Tumor suppressors and cell-cycle proteins in lung cancer |
| Q27308744 | Tumor treating fields perturb the localization of septins and cause aberrant mitotic exit |
| Q73487714 | Two different modes of cyclin clb2 proteolysis during mitosis in Saccharomyces cerevisiae |
| Q64935679 | UBE2C overexpression in melanoma and its essential role in G2/M transition. |
| Q101140335 | Ubiquitin signaling in cell cycle control and tumorigenesis |
| Q39559509 | Ubiquitin-specific protease 22 is a deubiquitinase of CCNB1. |
| Q36565972 | Unattached kinetochores rather than intrakinetochore tension arrest mitosis in taxol-treated cells |
| Q38992135 | Using in vivo biotinylated ubiquitin to describe a mitotic exit ubiquitome from human cells. |
| Q36293815 | Visualization of Mad2 dynamics at kinetochores, along spindle fibers, and at spindle poles in living cells |
| Q47105112 | Visualizing the complex functions and mechanisms of the anaphase promoting complex/cyclosome (APC/C). |
| Q37702038 | Welcome to a new kind of tension: translating kinetochore mechanics into a wait-anaphase signal |
| Q42924839 | c-Myb contributes to G2/M cell cycle transition in human hematopoietic cells by direct regulation of cyclin B1 expression |
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