Drosomycin-like defensin, a human homologue of Drosophila melanogaster drosomycin with antifungal activity

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Drosomycin-like defensin, a human homologue of Drosophila melanogaster drosomycin with antifungal activity is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/AAC.00155-07
P932PMC publication ID2292511
P698PubMed publication ID18212107
P5875ResearchGate publication ID5639843

P50authorJos W. M. van der MeerQ6279152
Mihai NeteaQ24517868
Anna SimonQ37385431
Otto C. BoermanQ57233096
Patrick ZeeuwenQ57321444
Bart Jan KullbergQ62560089
Paul E. VerweijQ70514014
P2093author name stringJoost Schalkwijk
Brian Tripet
Robert Hodges
Johanna van der Ven-Jongekrijg
P2860cites workBeta-defensins: linking innate and adaptive immunity through dendritic and T cell CCR6Q22010648
Long-range sequence analysis in Xq28: thirteen known and six candidate genes in 219.4 kb of high GC DNA between the RCP/GCP and G6PD lociQ24314458
A family of human receptors structurally related to Drosophila TollQ24321888
Crystal structure of defensin HNP-3, an amphiphilic dimer: mechanisms of membrane permeabilizationQ27658909
Toll-like receptorsQ27860671
The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adultsQ28289939
Antimicrobial peptides in mammalian and insect host defenceQ33536544
Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharideQ33938936
Participation of mammalian defensins and cathelicidins in anti-microbial immunity: receptors and activities of human defensins and cathelicidin (LL-37).Q34254888
Insect immunity. Septic injury of Drosophila induces the synthesis of a potent antifungal peptide with sequence homology to plant antifungal peptides.Q34314919
Immune sensing of Candida albicans requires cooperative recognition of mannans and glucans by lectin and Toll-like receptorsQ34619615
The immune response of DrosophilaQ35577920
Infections due to emerging and uncommon medically important fungal pathogensQ35641420
Modulation of human beta-defensin-2 transcription in pulmonary epithelial cells by lipopolysaccharide-stimulated mononuclear phagocytes via proinflammatory cytokine productionQ40656602
Toll-like receptor 4-dependent activation of dendritic cells by beta-defensin 2.Q40692879
Human Toll-like receptor 2 mediates induction of the antimicrobial peptide human beta-defensin 2 in response to bacterial lipoproteinQ40763230
Insect immunity. Isolation from the lepidopteran Heliothis virescens of a novel insect defensin with potent antifungal activityQ42058984
Normal keratinocytes express Toll-like receptors (TLRs) 1, 2 and 5: modulation of TLR expression in chronic plaque psoriasisQ42441343
The active site of drosomycin, a small insect antifungal protein, delineated by comparison with the modeled structure of Rs-AFP2, a plant antifungal proteinQ42637673
Activation of Drosophila Toll during fungal infection by a blood serine proteaseQ43169335
The role of toll-like receptor (TLR) 2 and TLR4 in the host defense against disseminated candidiasisQ44933430
Structure-activity relationships in defensin dimers: a novel link between beta-defensin tertiary structure and antimicrobial activityQ45022873
Direct bacterial protein PAMP recognition by human NK cells involves TLRs and triggers alpha-defensin productionQ47422836
Drosophila immunityQ47895639
The contribution of the Toll-like/IL-1 receptor superfamily to innate and adaptive immunity to fungal pathogens in vivo.Q51024797
Determination of the disulfide array of the first inducible antifungal peptide from insects: drosomycin from Drosophila melanogaster.Q52550625
Sequence and gene content in 52 kb including and centromeric to the G6PD gene in Xq28Q61978486
Endurance run increases circulating IL-6 and IL-1ra but downregulates ex vivo TNF-alpha and IL-1 beta productionQ70984018
Aspergillus fumigatus evades immune recognition during germination through loss of toll-like receptor-4-mediated signal transductionQ73646662
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectDrosophila melanogasterQ130888
FAM3 metabolism regulating signaling molecule AQ21101260
negative regulation of antifungal innate immune responseQ24500550
Drosomycin Dmel_CG10810Q29812129
P1104number of pages6
P304page(s)1407-1412
P577publication date2008-01-22
P1433published inAntimicrobial Agents and ChemotherapyQ578004
P1476titleDrosomycin-like defensin, a human homologue of Drosophila melanogaster drosomycin with antifungal activity
P478volume52

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cites work (P2860)
Q27321184A comparison of the transcriptome of Drosophila melanogaster in response to entomopathogenic fungus, ionizing radiation, starvation and cold shock.
Q37404678Alarmins and antimicrobial immunity.
Q28482430Antagonistic regulation, yet synergistic defense: effect of bergapten and protease inhibitor on development of cowpea bruchid Callosobruchus maculatus
Q30482669Drosophila melanogaster as a model host to dissect the immunopathogenesis of zygomycosis
Q36198238Establishing a reference array for the CS-αβ superfamily of defensive peptides
Q43911990FOXO-dependent regulation of innate immune homeostasis
Q33673156Human antimicrobial peptides and proteins
Q33408059Inducible expression of beta defensins by human respiratory epithelial cells exposed to Aspergillus fumigatus organisms.
Q36460651Innate Immunity and the Role of Epithelial Barrier During Aspergillus fumigatus Infection.
Q37943844Innate immunity against moulds: lessons learned from invertebrate models
Q37492735Novel antifungal agents, targets or therapeutic strategies for the treatment of invasive fungal diseases: a review of the literature (2005-2009).
Q45406125Polar characterization of antifungal peptides from APD2 Database
Q37882410Specificity and signaling in the Drosophila immune response.

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