Control of immune cell entry through the tumour vasculature: a missing link in optimising melanoma immunotherapy?

scientific article (publication date: March 2017)

Control of immune cell entry through the tumour vasculature: a missing link in optimising melanoma immunotherapy? is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/CTI.2017.7
P932PMC publication ID5382436
P698PubMed publication ID28435677

P50authorClaudine S. BonderQ91341775
Lisa M EbertQ57415932
P2093author name stringMichael P Brown
Zvi G Fridlender
Carmela Martini
Lih Yin Tan
P2860cites workRecruitment of monocytes/macrophages by tissue factor-mediated coagulation is essential for metastatic cell survival and premetastatic niche establishment in miceQ83427822
Overexpression of CXCL5 mediates neutrophil infiltration and indicates poor prognosis for hepatocellular carcinomaQ84405957
Maximal T cell-mediated antitumor responses rely upon CCR5 expression in both CD4(+) and CD8(+) T cellsQ84470745
Integrin alphaDbeta2, an adhesion receptor up-regulated on macrophage foam cells, exhibits multiligand-binding propertiesQ24538851
Durable complete responses in heavily pretreated patients with metastatic melanoma using T-cell transfer immunotherapyQ24596055
Platelets Guide Leukocytes to Their Sites of ExtravasationQ27342832
Immune checkpoint blockade: a common denominator approach to cancer therapyQ28083981
Facilitating T Cell Infiltration in Tumor Microenvironment Overcomes Resistance to PD-L1 BlockadeQ28119095
Platelet chemokines and chemokine receptors: linking hemostasis, inflammation, and host defenseQ28186087
Combined Nivolumab and Ipilimumab or Monotherapy in Untreated MelanomaQ29615443
Polarization of tumor-associated neutrophil phenotype by TGF-beta: "N1" versus "N2" TANQ29619346
Chemokine receptor patterns in lymphocytes mirror metastatic spreading in melanoma.Q30358552
Vascular channels formed by subpopulations of PECAM1+ melanoma cellsQ30413784
Chemokine expression in melanoma metastases associated with CD8+ T-cell recruitmentQ30415355
CXC chemokine receptor 3 expression by activated CD8+ T cells is associated with survival in melanoma patients with stage III diseaseQ30435000
A novel function of junctional adhesion molecule-C in mediating melanoma cell metastasis.Q30501230
Quantitative expression of VEGF, VEGF-R1, VEGF-R2, and VEGF-R3 in melanoma tissue microarraysQ33665758
Tumor endothelium FasL establishes a selective immune barrier promoting tolerance in tumorsQ33765767
Response to BRAF inhibition in melanoma is enhanced when combined with immune checkpoint blockadeQ33898182
BRAF inhibition increases tumor infiltration by T cells and enhances the antitumor activity of adoptive immunotherapy in miceQ33996674
Platelets guide the formation of early metastatic nichesQ34002250
Adoptive cell transfer as personalized immunotherapy for human cancerQ34043643
Leukocyte recruitment at sites of tumor: dissonant orchestrationQ34330220
Neoantigens in cancer immunotherapy.Q34470074
The role of chemokines in melanoma tumor growth and metastasisQ34680888
CD73 has distinct roles in nonhematopoietic and hematopoietic cells to promote tumor growth in miceQ35015717
Galectin-3 expression correlates with apoptosis of tumor-associated lymphocytes in human melanoma biopsiesQ35088257
Chemokine nitration prevents intratumoral infiltration of antigen-specific T cells.Q35237477
BRAF Inhibition Stimulates Melanoma-Associated Macrophages to Drive Tumor GrowthQ35251663
Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancerQ35463514
Induction of Vasculogenic Mimicry Overrides VEGF-A Silencing and Enriches Stem-like Cancer Cells in MelanomaQ35463820
Tumor angiogenesis induced by granulocyte chemotactic protein-2 as a countercurrent principleQ35746831
Melanoma-associated expression of transforming growth factor-beta isoformsQ35773976
Monocytic CCR2(+) myeloid-derived suppressor cells promote immune escape by limiting activated CD8 T-cell infiltration into the tumor microenvironmentQ35783465
CANCER IMMUNOLOGY. The "cancer immunogram".Q36010386
Non-redundant requirement for CXCR3 signalling during tumoricidal T-cell trafficking across tumour vascular checkpointsQ36160526
Transduction of tumor-specific T cells with CXCR2 chemokine receptor improves migration to tumor and antitumor immune responsesQ36333963
Endothelial vascular cell adhesion molecule 1 expression is suppressed by melanoma and carcinomaQ36364471
Elevated neutrophil and monocyte counts in peripheral blood are associated with poor survival in patients with metastatic melanoma: a prognostic modelQ36615128
Dynamic Patterns of Clonal Evolution in Tumor Vasculature Underlie Alterations in Lymphocyte-Endothelial Recognition to Foster Tumor Immune EscapeQ36693233
Using macrophage activation to augment immunotherapy of established tumoursQ36747346
Systemic blockade of transforming growth factor-beta signaling augments the efficacy of immunogene therapyQ37087603
Phase II study of vemurafenib followed by ipilimumab in patients with previously untreated BRAF-mutated metastatic melanomaQ37178677
CXCR3/CCR5 pathways in metastatic melanoma patients treated with adoptive therapy and interleukin-2.Q37279217
Adenosine limits the therapeutic effectiveness of anti-CTLA4 mAb in a mouse melanoma modelQ37650141
Blood vessel maturation, vascular phenotype and angiogenic potential in malignant melanoma: one step forward for overcoming anti-angiogenic drug resistance?Q37846342
Tumor-associated macrophages: functional diversity, clinical significance, and open questionsQ38105286
Regulatory T cells in cancer immunotherapyQ38177627
How leukocytes cross the vascular endotheliumQ38608338
Tumor cell vascular mimicry: Novel targeting opportunity in melanomaQ38710798
GD2-specific CAR T Cells Undergo Potent Activation and Deletion Following Antigen Encounter but can be Protected From Activation-induced Cell Death by PD-1 BlockadeQ38782845
Resistance to combination BRAF and MEK inhibition in metastatic melanoma: Where to next?Q38845962
BRAF and MEK inhibition variably affect GD2-specific chimeric antigen receptor (CAR) T-cell function in vitroQ38938635
Tumor-associated neutrophils (TAN) develop pro-tumorigenic properties during tumor progressionQ39087629
Vemurafenib reverses immunosuppression by myeloid derived suppressor cellsQ39445924
A galectin-3 ligand corrects the impaired function of human CD4 and CD8 tumor-infiltrating lymphocytes and favors tumor rejection in miceQ39666028
Endothelin B receptor mediates the endothelial barrier to T cell homing to tumors and disables immune therapy.Q40031362
Targeting tumor-associated macrophages and inhibition of MCP-1 reduce angiogenesis and tumor growth in a human melanoma xenograftQ40140782
Tumour-associated macrophage infiltration, neovascularization and aggressiveness in malignant melanoma: role of monocyte chemotactic protein-1 and vascular endothelial growth factor-A.Q40369844
High neutrophil to lymphocyte ratio measured before starting ipilimumab treatment is associated with reduced overall survival in patients with melanoma.Q40569572
Melanoma Induces, and Adenosine Suppresses, CXCR3-Cognate Chemokine Production and T-cell Infiltration of Lungs Bearing Metastatic-like Disease.Q40864107
Recurrence of melanoma following T cell treatment: continued antigen expression in a tumor that evades T cell recruitmentQ41150808
Myeloid Cells and Related Chronic Inflammatory Factors as Novel Predictive Markers in Melanoma Treatment with IpilimumabQ41469907
VEGF Neutralization Plus CTLA-4 Blockade Alters Soluble and Cellular Factors Associated with Enhancing Lymphocyte Infiltration and Humoral Recognition in MelanomaQ41636554
Endothelial P-selectin expression is reduced in advanced primary melanoma and melanoma metastasis.Q41971783
Strong expression of the lymphoattractant C-X-C chemokine Mig is associated with heavy infiltration of T cells in human malignant melanomaQ42482085
Integrin CD11c/CD18 α-chain phosphorylation is functionally important.Q42905780
Chemotherapy induces intratumoral expression of chemokines in cutaneous melanoma, favoring T-cell infiltration and tumor control.Q43665853
Frequencies of circulating MDSC correlate with clinical outcome of melanoma patients treated with ipilimumabQ44017442
Favorable outcome in clinically stage II melanoma patients is associated with the presence of activated tumor infiltrating T-lymphocytes and preserved MHC class I antigen expressionQ45201798
Low-dose irradiation programs macrophage differentiation to an iNOS⁺/M1 phenotype that orchestrates effective T cell immunotherapyQ46817579
Selective BRAF inhibitors induce marked T-cell infiltration into human metastatic melanomaQ47573472
L1 adhesion molecule on human lymphocytes and monocytes: expression and involvement in binding to alpha v beta 3 integrinQ48059490
Three-year follow-up of advanced melanoma patients who received ipilimumab plus fotemustine in the Italian Network for Tumor Biotherapy (NIBIT)-M1 phase II studyQ48401064
Expression of the endothelin-B receptor in pigment cell lesions of the skin. Evidence for its role as tumor progression marker in malignant melanoma.Q50505009
VEGF suppresses T-lymphocyte infiltration in the tumor microenvironment through inhibition of NF-κB-induced endothelial activation.Q50848908
Human solid tumors contain high endothelial venules: association with T- and B-lymphocyte infiltration and favorable prognosis in breast cancer.Q50996147
Macrophage infiltration correlates with tumor stage and angiogenesis in human malignant melanoma: possible involvement of TNFalpha and IL-1alpha.Q52832336
Tumor vasculogenic mimicry predicts poor prognosis in cancer patients: a meta-analysis.Q53168767
Intratumoral neutrophils and plasmacytoid dendritic cells indicate poor prognosis and are associated with pSTAT3 expression in AJCC stage I/II melanoma.Q53281128
Combination of T-cell therapy and trigger of inflammation induces remodeling of the vasculature and tumor eradication.Q53391760
Leukocyte infiltration and tumor cell plasticity are parameters of aggressiveness in primary cutaneous melanoma.Q54133911
CXCR2-mediated tumor-associated neutrophil recruitment is regulated by IFN-β.Q54704650
An immune-active tumor microenvironment favors clinical response to ipilimumabQ56898024
Macrophage infiltration is associated with VEGF and EGFR expression in breast cancerQ58212139
A study of adhesion molecules as markers of progression in malignant melanomaQ58212505
Epigenetic Regulation of Tumor Endothelial Cell Anergy: Silencing of Intercellular Adhesion Molecule-1 by Histone ModificationsQ60541942
Differential response of primary and metastatic melanomas to neutrophils attracted by IL-8Q61609536
Low-Level Monocyte Chemoattractant Protein-1 Stimulation of Monocytes Leads to Tumor Formation in Nontumorigenic Melanoma CellsQ61609539
A chemokine receptor antagonist inhibits experimental breast tumor growthQ61819228
Prognostic factors in patients with metastatic malignant melanoma. A multivariate analysisQ72559262
Tumor angiogenesis modulates leukocyte-vessel wall interactions in vivo by reducing endothelial adhesion molecule expressionQ73344300
T-cell activation marker expression on tumor-infiltrating lymphocytes as prognostic factor in cutaneous malignant melanomaQ75402946
T-cell distribution and adhesion receptor expression in metastatic melanomaQ80249359
Role of galectin-3 in leukocyte recruitment in a murine model of lung infection by Streptococcus pneumoniaeQ80633633
The predictive value of CD8, CD4, CD68, and human leukocyte antigen-D-related cells in the prognosis of cutaneous malignant melanoma with vertical growth phaseQ81000005
Utility of tumour-infiltrating CD25+FOXP3+ regulatory T cell evaluation in predicting local recurrence in vertical growth phase cutaneous melanomaQ81393637
Distinct expression of CXCL8 and its receptors CXCR1 and CXCR2 and their association with vessel density and aggressiveness in malignant melanomaQ82174987
Inhibition of neutrophil infiltration into A549 lung tumors in vitro and in vivo using a CXCR2-specific antagonist is associated with reduced tumor growthQ83427428
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectimmunotherapyQ1427096
P304page(s)e134
P577publication date2017-03-17
P1433published inClinical & translational immunologyQ27725955
P1476titleControl of immune cell entry through the tumour vasculature: a missing link in optimising melanoma immunotherapy?
P478volume6

Reverse relations

cites work (P2860)
Q60938431A Computational Approach Identifies Immunogenic Features of Prognosis in Human Cancers
Q93270141Effects of anti-PD-1 immunotherapy on tumor regression: insights from a patient-derived xenograft model
Q91779668Immunogenomics of Colorectal Tumors: Facts and Hypotheses on an Evolving Saga
Q51765579Molecular Magnetic Resonance Imaging of Endothelial Activation in the Central Nervous System.
Q58607867Nondestructive, multiplex three-dimensional mapping of immune infiltrates in core needle biopsy
Q49166013Overexpression of adhesion molecules and barrier molecules is associated with differential infiltration of immune cells in non-small cell lung cancer
Q41935730Targeting myeloid derived suppressor cells with all-trans retinoic acid is highly time-dependent in therapeutic tumor vaccination
Q55343888Transcriptome-derived stromal and immune scores infer clinical outcomes of patients with cancer.
Q92855987Uveal Melanoma, Angiogenesis and Immunotherapy, Is There Any Hope?

Search more.