review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Alexander E. Gorbalenya | Q47451293 |
Maxim Khasnatinov | Q54438314 | ||
Naomi L Forrester | Q88670736 | ||
Tamara S. Gritsun | Q110674288 | ||
Ernest A. Gould | Q24701585 | ||
Bruno Canard | Q28039067 | ||
Hélène Malet | Q28039103 | ||
P2093 | author name string | X de Lamballerie | |
S Weaver | |||
S Jamal | |||
I Delogu | |||
B Morin | |||
B Coutard | |||
C Baronti | |||
G Moureau | |||
P2860 | cites work | A single mutation in chikungunya virus affects vector specificity and epidemic potential | Q21131599 |
Out of Africa: a molecular perspective on the introduction of yellow fever virus into the Americas | Q21131608 | ||
Identification of a Novel Function of theAlphavirusCapping Apparatus | Q56878291 | ||
A new superfamily of replicative proteins | Q59069349 | ||
Antigenic Relationships of Group a Arboviruses by Plaque Reduction Neutralization Testing | Q67312975 | ||
Venezuelan equine encephalitis | Q69359388 | ||
Long-term duration of detectable neutralizing antibodies after administration of live-attenuated VEE vaccine and following booster vaccination with inactivated VEE vaccine | Q71356875 | ||
Genome microevolution of chikungunya viruses causing the Indian Ocean outbreak | Q21144706 | ||
Chikungunya virus adapts to tiger mosquito via evolutionary convergence: a sign of things to come? | Q21245126 | ||
A mouse model for Chikungunya: young age and inefficient type-I interferon signaling are risk factors for severe disease | Q21559504 | ||
Spread of the tiger: global risk of invasion by the mosquito Aedes albopictus | Q24289219 | ||
Chikungunya, an epidemic arbovirosis | Q24291001 | ||
Evolutionary relationships and systematics of the alphaviruses | Q24529186 | ||
RNA virus error catastrophe: direct molecular test by using ribavirin | Q24599371 | ||
Techniques for hemagglutination and hemagglutination-inhibition with arthropod-borne viruses | Q24696032 | ||
Yellow fever in South Wales, 1865 | Q24792724 | ||
A highly specific phosphatase that acts on ADP-ribose 1''-phosphate, a metabolite of tRNA splicing in Saccharomyces cerevisiae | Q24802001 | ||
Pegylated alpha interferon is an effective treatment for virulent venezuelan equine encephalitis virus and has profound effects on the host immune response to infection | Q27469593 | ||
Effects of palmitoylation of replicase protein nsP1 on alphavirus infection | Q27469680 | ||
Modification of the 5' terminus of Sindbis virus genomic RNA allows nsP4 RNA polymerases with nonaromatic amino acids at the N terminus to function in RNA replication | Q27473100 | ||
Global traffic and disease vector dispersal | Q27473134 | ||
Catalytic Core of Alphavirus Nonstructural Protein nsP4 Possesses Terminal Adenylyltransferase Activity | Q27477547 | ||
Effects of chloroquine and cytochalasin B on the infection of cells by Sindbis virus and vesicular stomatitis virus | Q27477806 | ||
Role of the Amphipathic Peptide of Semliki Forest Virus Replicase Protein nsP1 in Membrane Association and Virus Replication | Q27478041 | ||
Enzymatic Defects of the nsP2 Proteins of Semliki Forest Virus Temperature-Sensitive Mutants | Q27478372 | ||
Seco-pregnane steroids target the subgenomic RNA of alphavirus-like RNA viruses | Q27478419 | ||
Recombinational history and molecular evolution of western equine encephalomyelitis complex alphaviruses | Q27480774 | ||
Proteolytic activation of tick-borne encephalitis virus by furin | Q27480892 | ||
Regulation of Sindbis virus RNA replication: uncleaved P123 and nsP4 function in minus-strand RNA synthesis, whereas cleaved products from P123 are required for efficient plus-strand RNA synthesis | Q27485961 | ||
ATPase and GTPase activities associated with Semliki Forest virus nonstructural protein nsP2 | Q27485993 | ||
Expression of Semliki Forest virus nsP1-specific methyltransferase in insect cells and in Escherichia coli | Q27486003 | ||
Inhibition of alphavirus infection in cell culture and in mice with antisense morpholino oligomers | Q27486413 | ||
Mutagenesis of the in-frame opal termination codon preceding nsP4 of Sindbis virus: studies of translational readthrough and its effect on virus replication | Q27486486 | ||
Increased Mortality Rate Associated with Chikungunya Epidemic, Ahmedabad, India | Q27487078 | ||
Chimeric alphavirus vaccine candidates for chikungunya | Q27487105 | ||
Susceptibility of Florida mosquitoes to infection with chikungunya virus | Q27487145 | ||
Immunogenicity of novel consensus-based DNA vaccines against Chikungunya virus | Q27487330 | ||
Treatment of Venezuelan equine encephalitis virus infection with (−)-carbodine | Q27487534 | ||
Chikungunya Virus and Central Nervous System Infections in Children, India | Q27488268 | ||
The nsP3 macro domain is important for Sindbis virus replication in neurons and neurovirulence in mice | Q27488409 | ||
The Crystal Structures of Chikungunya and Venezuelan Equine Encephalitis Virus nsP3 Macro Domains Define a Conserved Adenosine Binding Pocket | Q27488798 | ||
Molecular cloning, overproduction, purification and biochemical characterization of the p39 nsp2 protease domains encoded by three alphaviruses | Q27488874 | ||
Mapping the Structure and Function of the E1 and E2 Glycoproteins in Alphaviruses | Q27489867 | ||
Western equine encephalitis virus is a recombinant virus | Q27490908 | ||
Membrane binding mechanism of an RNA virus-capping enzyme | Q27627017 | ||
The Fusion glycoprotein shell of Semliki Forest virus: an icosahedral assembly primed for fusogenic activation at endosomal pH | Q27631190 | ||
Crystal structures of the X-domains of a Group-1 and a Group-3 coronavirus reveal that ADP-ribose-binding may not be a conserved property | Q27653582 | ||
The alphaviruses: gene expression, replication, and evolution | Q27860954 | ||
Structure and mechanism of ADP-ribose-1''-monophosphatase (Appr-1''-pase), a ubiquitous cellular processing enzyme | Q27937235 | ||
A comparison of the nucleotide sequences of eastern and western equine encephalomyelitis viruses with those of other alphaviruses and related RNA viruses | Q28249445 | ||
Broad-spectrum antiviral activity of carbodine, the carbocyclic analogue of cytidine | Q28323208 | ||
Inhibitory effect of selected antiviral compounds on arenavirus replication in vitro | Q28328863 | ||
Infection with chikungunya virus in Italy: an outbreak in a temperate region | Q29346487 | ||
Antigenic variants of Venezuelan equine encephalitis virus: their geographic distribution and epidemiologic significance | Q29354416 | ||
Transmission cycles, host range, evolution and emergence of arboviral disease | Q29616258 | ||
Primary structural comparison of RNA-dependent polymerases from plant, animal and bacterial viruses | Q29617489 | ||
Changing patterns of chikungunya virus: re-emergence of a zoonotic arbovirus | Q29620003 | ||
Structure and mechanism of helicases and nucleic acid translocases | Q29620151 | ||
The VIZIER project: preparedness against pathogenic RNA viruses | Q30229225 | ||
Molecular phylogenetics of the RrmJ/fibrillarin superfamily of ribose 2'-O-methyltransferases. | Q30332409 | ||
Elimination of phosphorylation sites of Semliki Forest virus replicase protein nsP3. | Q31649623 | ||
In vitro inhibition of Chikungunya and Semliki Forest viruses replication by antiviral compounds: synergistic effect of interferon-alpha and ribavirin combination | Q33195882 | ||
Identification of compounds with anti-West Nile Virus activity | Q33236579 | ||
Impact of climate change and other factors on emerging arbovirus diseases | Q33370244 | ||
Replicase complex genes of Semliki Forest virus confer lethal neurovirulence | Q33804386 | ||
RNA helicase activity of Semliki Forest virus replicase protein NSP2. | Q33859798 | ||
Complete sequence of the genomic RNA of O'nyong-nyong virus and its use in the construction of alphavirus phylogenetic trees | Q33893536 | ||
Cleavage-site preferences of Sindbis virus polyproteins containing the non-structural proteinase. Evidence for temporal regulation of polyprotein processing in vivo | Q33924220 | ||
Phase II safety and immunogenicity study of live chikungunya virus vaccine TSI-GSD-218. | Q33942533 | ||
Host range, amplification and arboviral disease emergence. | Q33992289 | ||
Chikungunya outbreaks--the globalization of vectorborne diseases | Q34002554 | ||
On chikungunya acute infection and chloroquine treatment | Q34012738 | ||
Functional analysis of nsP3 phosphoprotein mutants of Sindbis virus | Q34227437 | ||
Identification of the active site residues in the nsP2 proteinase of Sindbis virus | Q34263496 | ||
Origins, evolution, and vector/host coadaptations within the genus Flavivirus | Q34286382 | ||
Evolution, epidemiology, and dispersal of flaviviruses revealed by molecular phylogenies | Q34419822 | ||
Replication and clearance of Venezuelan equine encephalitis virus from the brains of animals vaccinated with chimeric SIN/VEE viruses | Q34434918 | ||
Invasions by insect vectors of human disease | Q34453718 | ||
Mayaro virus: complete nucleotide sequence and phylogenetic relationships with other alphaviruses | Q34475206 | ||
The anti-yellow fever virus activity of ribavirin is independent of error-prone replication | Q34485851 | ||
Conservation of the putative methyltransferase domain: a hallmark of the 'Sindbis-like' supergroup of positive-strand RNA viruses | Q34490438 | ||
Evolutionary conservation of histone macroH2A subtypes and domains | Q34668581 | ||
Reaction in alphavirus mRNA capping: formation of a covalent complex of nonstructural protein nsP1 with 7-methyl-GMP. | Q34775056 | ||
L-nucleosides: antiviral activity and molecular mechanism | Q34779807 | ||
Nucleotide triphosphatase/helicase of hepatitis C virus as a target for antiviral therapy | Q34807255 | ||
Characterization of purified Sindbis virus nsP4 RNA-dependent RNA polymerase activity in vitro | Q35023244 | ||
Venezuelan equine encephalitis | Q35598701 | ||
Alphavirus nsP3 functions to form replication complexes transcribing negative-strand RNA | Q36636147 | ||
Chloroquine enhances replication of Semliki Forest virus and encephalomyocarditis virus in mice | Q36680744 | ||
Role for conserved residues of sindbis virus nonstructural protein 2 methyltransferase-like domain in regulation of minus-strand synthesis and development of cytopathic infection | Q36804640 | ||
Genetic stability among temporally and geographically diverse isolates of Barmah Forest virus | Q36881507 | ||
Effects of lysosomotropic weak bases on infection of BHK-21 cells by Sindbis virus. | Q36896646 | ||
Cross-neutralization studies with group A arthropod-borne viruses. | Q36913324 | ||
Molecular strategies to inhibit the replication of RNA viruses | Q37099776 | ||
Selective inhibitors of picornavirus replication | Q37125475 | ||
Venezuelan equine encephalitis emergence: enhanced vector infection from a single amino acid substitution in the envelope glycoprotein | Q37388695 | ||
A novel superfamily of nucleoside triphosphate-binding motif containing proteins which are probably involved in duplex unwinding in DNA and RNA replication and recombination | Q39243948 | ||
Antigenic Relationships of Alphaviruses by a Simple Micro-culture Cross-neutralization Method | Q39423135 | ||
Template-dependent initiation of Sindbis virus RNA replication in vitro | Q39579511 | ||
Re-emergence of epidemic Venezuelan equine encephalomyelitis in South America. VEE Study Group | Q39582642 | ||
Ribavirin causes error catastrophe during Hantaan virus replication. | Q39698441 | ||
A new role for ns polyprotein cleavage in Sindbis virus replication | Q39767616 | ||
Substitutions of 169Lys and 173Thr in nonstructural protein 1 influence the infectivity and pathogenicity of XJ-160 virus | Q39899505 | ||
A mutant of Sindbis virus which is able to replicate in cells with reduced CTP makes a replicase/transcriptase with a decreased Km for CTP. | Q39961147 | ||
Inhibition of Chikungunya virus infection in cultured human muscle cells by furin inhibitors: impairment of the maturation of the E2 surface glycoprotein | Q39971773 | ||
Expression and biochemical characterization of nsP2 cysteine protease of Chikungunya virus | Q40160382 | ||
Inhibition of multiple strains of Venezuelan equine encephalitis virus by a pool of four short interfering RNAs | Q40198668 | ||
Sindbis virus nonstructural protein nsP2 is cytotoxic and inhibits cellular transcription | Q40274399 | ||
Deletions in the hypervariable domain of the nsP3 gene attenuate Semliki Forest virus virulence | Q40306678 | ||
The predominant mechanism by which ribavirin exerts its antiviral activity in vitro against flaviviruses and paramyxoviruses is mediated by inhibition of IMP dehydrogenase | Q40517134 | ||
Direct fluorometric measurement of hepatitis C virus helicase activity | Q40549110 | ||
Tolerability of modified tick-borne encephalitis vaccine FSME-IMMUN "NEW" in children: results of post-marketing surveillance | Q40567459 | ||
The effect of ribavirin and IMPDH inhibitors on hepatitis C virus subgenomic replicon RNA. | Q40643235 | ||
Use of the yellow fever virus vaccine strain 17D for the study of strategies for the treatment of yellow fever virus infections. | Q40668883 | ||
Alphavirus positive and negative strand RNA synthesis and the role of polyproteins in formation of viral replication complexes. | Q40672583 | ||
Chikungunya Virus Vaccine Prepared by Tween-Ether Extraction | Q40712673 | ||
Polypeptide requirements for assembly of functional Sindbis virus replication complexes: a model for the temporal regulation of minus- and plus-strand RNA synthesis | Q40792314 | ||
Deletion and duplication mutations in the C-terminal nonconserved region of Sindbis virus nsP3: effects on phosphorylation and on virus replication in vertebrate and invertebrate cells | Q41459294 | ||
Phosphorylation of Sindbis virus nsP3 in vivo and in vitro | Q41716721 | ||
SVLM21, a Sindbis virus mutant resistant to methionine deprivation, encodes an altered methyltransferase | Q41759394 | ||
In vitro inhibition of severe acute respiratory syndrome coronavirus by chloroquine | Q41913526 | ||
Chloroquine phosphate treatment of chronic Chikungunya arthritis. An open pilot study | Q41918756 | ||
Inhibition of Semliki forest virus penetration by lysosomotropic weak bases | Q41923695 | ||
Effect of chloroquine on the growth of animal viruses | Q41936128 | ||
Comparison of the antiviral activity in vitro of some non-steroidal anti-inflammatory drugs | Q41939418 | ||
Semliki Forest virus mRNA capping enzyme requires association with anionic membrane phospholipids for activity | Q42034834 | ||
Chikungunya disease outbreak, Reunion Island. | Q42616934 | ||
Aura virus is a New World representative of Sindbis-like viruses | Q42684044 | ||
Activity of ribavirin against Hantaan virus correlates with production of ribavirin-5'-triphosphate, not with inhibition of IMP dehydrogenase. | Q42718871 | ||
Identification of a ribavirin-resistant NS5B mutation of hepatitis C virus during ribavirin monotherapy | Q42980354 | ||
Epidemic Venezuelan equine encephalitis in La Guajira, Colombia, 1995. | Q42981954 | ||
High-throughput screening assay of hepatitis C virus helicase inhibitors using fluorescence-quenching phenomenon. | Q42984520 | ||
Mutations that confer resistance to mycophenolic acid and ribavirin on sindbis virus map to the nonstructural protein nsP1 | Q42986339 | ||
Vectors vs. humans in Australia--who is on top down under? An update on vector-borne disease and research on vectors in Australia. | Q42989209 | ||
Association of the Sindbis virus RNA methyltransferase activity with the nonstructural protein nsP1. | Q42990081 | ||
Sindbis virus mutants resistant to mycophenolic acid and ribavirin | Q42992087 | ||
Persistence in humans of antibody to subtypes of Venezuelan equine encephalomyelitis (VEE) virus after immunization with attenuated (TC-83) VEE virus vaccine | Q43514367 | ||
Expression of sindbis virus nsP1 and methyltransferase activity inEscherichia coli | Q43571353 | ||
The crystal structure of the Venezuelan equine encephalitis alphavirus nsP2 protease | Q43589065 | ||
Guanosine nucleotide analogs as inhibitors of alphavirus mRNA capping enzyme | Q43624139 | ||
Site-specific protease activity of the carboxyl-terminal domain of Semliki Forest virus replicase protein nsP2. | Q43643522 | ||
The effects of palmitoylation on membrane association of Semliki forest virus RNA capping enzyme | Q43828148 | ||
On the use of chloroquine for chikungunya. | Q43973239 | ||
Inhibition of replication of Venezuelan equine encephalomyelitis with polyclonal antibodies to laminin-binding protein | Q44055458 | ||
Neurologic manifestations of pediatric chikungunya infection | Q44140290 | ||
Attenuated Mutants of Venezuelan Equine Encephalitis Virus Containing Lethal Mutations in the PE2 Cleavage Signal Combined with a Second-Site Suppressor Mutation in E1 | Q44169045 | ||
Sequelae of Venezuelan equine encephalitis in humans: a four year follow-up | Q44252532 | ||
Regulation of the sequential processing of Semliki Forest virus replicase polyprotein | Q44548826 | ||
Putative papain-related thiol proteases of positive-strand RNA viruses. Identification of rubi- and aphthovirus proteases and delineation of a novel conserved domain associated with proteases of rubi-, alpha- and coronaviruses | Q44808922 | ||
An animal model for studying the pathogenesis of chikungunya virus infection | Q44851012 | ||
Improved mucosal protection against Venezuelan equine encephalitis virus is induced by the molecularly defined, live-attenuated V3526 vaccine candidate | Q45742226 | ||
Mutagenesis of the Sindbis virus nsP1 protein: effects on methyltransferase activity and viral infectivity | Q45771191 | ||
Live, attenuated Venezuelan equine encephalomyelitis virus vaccine. I. Clinical effects in man. | Q45808070 | ||
P433 | issue | 2 | |
P921 | main subject | alphavirus infections | Q4735280 |
Chikungunya virus | Q15794049 | ||
emerging pathogen | Q108429945 | ||
P304 | page(s) | 111-124 | |
P577 | publication date | 2009-07-16 | |
2010-08-01 | |||
P1433 | published in | Antiviral Research | Q4775352 |
P1476 | title | Understanding the alphaviruses: recent research on important emerging pathogens and progress towards their control | |
P478 | volume | 87 |
Q41923647 | A compendium of small molecule direct-acting and host-targeting inhibitors as therapies against alphaviruses |
Q34015300 | A novel live-attenuated vaccine candidate for mayaro Fever |
Q44913691 | A simple model explains the dynamics of preferential host switching among mammal RNA viruses |
Q37890054 | An alternative pathway for alphavirus entry |
Q39614599 | Antiviral RNA interference responses induced by Semliki Forest virus infection of mosquito cells: characterization, origin, and frequency-dependent functions of virus-derived small interfering RNAs |
Q89977562 | Antivirals against Chikungunya Virus: Is the Solution in Nature? |
Q38228539 | Basics of virology. |
Q41933000 | Chikungunya disease and chloroquine treatment |
Q34222718 | Chikungunya disease: infection-associated markers from the acute to the chronic phase of arbovirus-induced arthralgia |
Q33907288 | Chikungunya outbreak in a rural area of Western Cameroon in 2006: A retrospective serological and entomological survey |
Q34120636 | Detection of all species of the genus Alphavirus by reverse transcription-PCR with diagnostic sensitivity |
Q59357882 | Development of an ELISA assay for screening inhibitors against divalent metal ion dependent alphavirus capping enzyme |
Q42222907 | Discovery of in silico hits targeting the nsP3 macro domain of chikungunya virus |
Q47269135 | Emerging Alphaviruses are Sensitive to Cellular States Induced by a Novel Small Molecule Agonist of the STING Pathway |
Q38156916 | Emerging arboviruses: Why today? |
Q35786348 | Evolutionary and Ecological Characterization of Mayaro Virus Strains Isolated during an Outbreak, Venezuela, 2010. |
Q24701730 | Evolutionary genetics and vector adaptation of recombinant viruses of the western equine encephalitis antigenic complex provides new insights into alphavirus diversity and host switching |
Q33890431 | Expecting the unexpected: nucleic acid-based diagnosis and discovery of emerging viruses |
Q37576241 | Genome-wide RNAi screen identifies SEC61A and VCP as conserved regulators of Sindbis virus entry |
Q24701727 | Global emergence of Alphaviruses that cause arthritis in humans |
Q41929353 | Impact of environmental factors on neglected emerging arboviral diseases |
Q34113650 | Inhibitors of alphavirus entry and replication identified with a stable Chikungunya replicon cell line and virus-based assays |
Q90343022 | Membrane binding and rearrangement by chikungunya virus capping enzyme nsP1 |
Q36304985 | Molecular Docking Studies to Explore Potential Binding Pockets and Inhibitors for Chikungunya Virus Envelope Glycoproteins |
Q36276696 | Myd88-dependent toll-like receptor 7 signaling mediates protection from severe Ross River virus-induced disease in mice |
Q35188739 | Natural resistance-associated macrophage protein is a cellular receptor for sindbis virus in both insect and mammalian hosts |
Q24288666 | New insights into flavivirus evolution, taxonomy and biogeographic history, extended by analysis of canonical and alternative coding sequences |
Q40051547 | Obatoclax Inhibits Alphavirus Membrane Fusion by Neutralizing the Acidic Environment of Endocytic Compartments |
Q33618170 | On the entry of an emerging arbovirus into host cells: Mayaro virus takes the highway to the cytoplasm through fusion with early endosomes and caveolae-derived vesicles. |
Q36384418 | Phenoloxidase activity acts as a mosquito innate immune response against infection with Semliki Forest virus |
Q34200300 | Rapid, specific detection of alphaviruses from tissue cultures using a replicon-defective reporter gene assay |
Q98906721 | Snapshots of ADP-ribose bound to Getah virus macro domain reveal an intriguing choreography |
Q38415017 | Temporal SILAC-based quantitative proteomics identifies host factors involved in chikungunya virus replication. |
Q37347319 | The Antiviral Alkaloid Berberine Reduces Chikungunya Virus-Induced Mitogen-Activated Protein Kinase Signaling |
Q37708361 | The VIZIER project: overview; expectations; and achievements |
Q57265533 | The genetics of alphaviruses |
Q34670977 | Towards antivirals against chikungunya virus |
Q37996242 | Virus entry: old viruses, new receptors |
Q24701721 | mRNA Capping by Venezuelan Equine Encephalitis Virus nsP1: Functional Characterization and Implications for Antiviral Research |
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