Monitoring C-Peptide Storage and Secretion in Islet β-Cells In Vitro and In Vivo.

scientific article

Monitoring C-Peptide Storage and Secretion in Islet β-Cells In Vitro and In Vivo. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.2337/DB15-1264
P932PMC publication ID4764152
P698PubMed publication ID26647386

P50authorArfah AnjumQ86872818
Robert KennedyQ86872820
David CastleQ86872822
P2093author name stringLeena Haataja
Peter Arvan
Shuaishuai Zhu
Dennis Larkin
Shusheng Lu
Candice Inouye
P2860cites workHigh resolution intravital imaging of subcellular structures of mouse abdominal organs using a microstage deviceQ27306080
A subset of 50 secretory granules in close contact with L-type Ca2+ channels accounts for first-phase insulin secretion in mouse beta-cellsQ27863714
Natural history of β-cell adaptation and failure in type 2 diabetesQ28082002
Pancreatic β-Cell Adaptive Plasticity in Obesity Increases Insulin Production but Adversely Affects Secretory FunctionQ30708894
Misfolded proinsulin affects bystander proinsulin in neonatal diabetesQ33581459
The Cell Physiology of Biphasic Insulin Secretion.Q34272522
Engineering and characterization of a superfolder green fluorescent proteinQ34478574
Stimulation of insulin secretion reveals heterogeneity of pancreatic B cells in vivoQ35575860
Pancreatic β cell dedifferentiation as a mechanism of diabetic β cell failureQ36241895
Proinsulin intermolecular interactions during secretory trafficking in pancreatic β cellsQ36543789
Islet β cell mass in diabetes and how it relates to function, birth, and deathQ36745536
Insulin granule biogenesis, trafficking and exocytosisQ37403987
Quantification of pancreatic islet distribution in situ in miceQ37474450
Stress and the inflammatory process: a major cause of pancreatic cell death in type 2 diabetes.Q37568237
Sorting and storage during secretory granule biogenesis: looking backward and looking forwardQ40855911
Role of reduced β-cell mass versus impaired β-cell function in the pathogenesis of type 2 diabetesQ41945969
Quantitative monitoring of insulin secretion from single islets of Langerhans in parallel on a microfluidic chipQ42058517
The stunned beta cell: a brief historyQ43073326
The deletion variant of nicotinamide nucleotide transhydrogenase (Nnt) does not affect insulin secretion or glucose toleranceQ43244153
Pathogenesis of NIDDM. A balanced overviewQ43832606
The effect of rate and dose of glucose infusion on the acute insulin response in manQ44008551
Pancreatic beta-cell mass in European subjects with type 2 diabetesQ46332814
Impaired islet function in commonly used transgenic mouse lines due to human growth hormone minigene expression.Q47100743
Imaging pancreatic beta-cells in the intact pancreas.Q50744722
Recapture after exocytosis causes differential retention of protein in granules of bovine chromaffin cells.Q50796308
Ultrastructural morphometric analysis of insulin secretory granules in human type 2 diabetesQ57503376
Deletion of Nicotinamide Nucleotide Transhydrogenase: A New Quantitive Trait Locus Accounting for Glucose Intolerance in C57BL/6J MiceQ64355613
The biosynthesis of the subtilisin-related proprotein convertase PC3, but no that of the PC2 convertase, is regulated by glucose in parallel to proinsulin biosynthesis in rat pancreatic isletsQ70578965
Kinetics of proinsulin conversion in human isletsQ70721752
The dual peroxisome proliferator-activated receptor alpha/gamma activator muraglitazar prevents the natural progression of diabetes in db/db miceQ79678420
Pancreatic beta-cells secrete insulin in fast- and slow-release formsQ82676084
P4510describes a project that usesImageJQ1659584
P433issue3
P407language of work or nameEnglishQ1860
P1104number of pages11
P304page(s)699-709
P577publication date2015-12-08
P1433published inDiabetesQ895262
P1476titleMonitoring C-Peptide Storage and Secretion in Islet β-Cells In Vitro and In Vivo
P478volume65

Reverse relations

cites work (P2860)
Q38724059Chaperone-Driven Degradation of a Misfolded Proinsulin Mutant in Parallel With Restoration of Wild-Type Insulin Secretion.
Q52726541Control of Insulin Granule Formation and Function by the ABC Transporters ABCG1 and ABCA1 and by Oxysterol Binding Protein OSBP.
Q36608783Emptying the Pool: Modular Insulin Secretion From the Pancreas
Q93364183Imaging Insulin Secretion from Mouse Pancreas by MRI Is Improved by Use of a Zinc-Responsive MRI Sensor with Lower Affinity for Zn2+ Ions
Q48152192Misfolded proinsulin in the endoplasmic reticulum during development of beta cell failure in diabetes.
Q39089307Probes for monitoring regulated exocytosis
Q36548431Regulation of Glucokinase by Intracellular Calcium Levels in Pancreatic β Cells
Q47117770Sulfonylurea for the treatment of neonatal diabetes owing to KATP-channel mutations: a systematic review and meta-analysis
Q55216417The role of beta cell heterogeneity in islet function and insulin release.