Site-directed disulfide bonding reveals an interaction site between energy-coupling protein TonB and BtuB, the outer membrane cobalamin transporter

scientific article published on September 1999

Site-directed disulfide bonding reveals an interaction site between energy-coupling protein TonB and BtuB, the outer membrane cobalamin transporter is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode1999PNAS...9610673C
P356DOI10.1073/PNAS.96.19.10673
P932PMC publication ID17941
P698PubMed publication ID10485884
P5875ResearchGate publication ID12814090

P50authorRobert J. KadnerQ116021146
P2093author name stringN Cadieux
P2860cites workElectrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applicationsQ24561689
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Q25938983
Siderophore-mediated iron transport: crystal structure of FhuA with bound lipopolysaccharideQ27766352
Transmembrane signaling across the ligand-gated FhuA receptor: crystal structures of free and ferrichrome-bound states reveal allosteric changesQ27766394
Crystal structure of the outer membrane active transporter FepA from Escherichia coliQ27766470
A site-directed spin-labeling study of ligand-induced conformational change in the ferric enterobactin receptor, FepA.Q30420006
Genetic suppression demonstrates interaction of TonB protein with outer membrane transport proteins in Escherichia coliQ30451874
Point mutations in a conserved region (TonB box) of Escherichia coli outer membrane protein BtuB affect vitamin B12 transportQ30451882
Vitamin B12 transport in Escherichia coli: energy coupling between membranesQ30451958
Genetic Analysis of Components Involved in Vitamin B 12 Uptake in Escherichia coliQ30452026
Regions of Escherichia coli TonB and FepA proteins essential for in vivo physical interactionsQ35623484
Specific in vivo labeling of cell surface-exposed protein loops: reactive cysteines in the predicted gating loop mark a ferrichrome binding site and a ligand-induced conformational change of the Escherichia coli FhuA protein.Q39564442
Transposition and fusion of the lac genes to selected promoters in Escherichia coli using bacteriophage lambda and MuQ39605636
Characterization of the exbBD operon of Escherichia coli and the role of ExbB and ExbD in TonB function and stability.Q39837993
Involvement of ExbB and TonB in transport across the outer membrane of Escherichia coli: phenotypic complementation of exb mutants by overexpressed tonB and physical stabilization of TonB by ExbBQ39950283
Functional Interaction of the tonA/tonB Receptor System in Escherichia coliQ39997076
TonB protein and energy transduction between membranesQ40734050
TonB-dependent iron acquisition: mechanisms of siderophore-mediated active transportQ47919308
Ligand-induced conformational change in the ferrichrome-iron receptor of Escherichia coli K-12.Q50192343
Partial suppression of an Escherichia coli TonB transmembrane domain mutation (delta V17) by a missense mutation in ExbB.Q54198381
Ligand-specific opening of a gated-porin channel in the outer membrane of living bacteria.Q54565627
Suppression of the btuB451 mutation by mutations in the tonB gene suggests a direct interaction between TonB and TonB-dependent receptor proteins in the outer membrane of Escherichia coli.Q54750034
Transmembrane Signaling across the Ligand-Gated FhuA ReceptorQ56838719
Transport across the outer membrane of Escherichia coli K12 via the FhuA receptor is regulated by the TonB protein of the cytoplasmic membraneQ69355204
Energy transduction between membranes. TonB, a cytoplasmic membrane protein, can be chemically cross-linked in vivo to the outer membrane receptor FepAQ72865408
Cell envelope signaling in Escherichia coli. Ligand binding to the ferrichrome-iron receptor fhua promotes interaction with the energy-transducing protein TonBQ73836174
Protonmotive force, ExbB and ligand-bound FepA drive conformational changes in TonBQ77345045
Active transport by customized beta-barrelsQ77787217
The genetics of disulfide bond metabolismQ77936221
P433issue19
P407language of work or nameEnglishQ1860
P304page(s)10673-10678
P577publication date1999-09-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleSite-directed disulfide bonding reveals an interaction site between energy-coupling protein TonB and BtuB, the outer membrane cobalamin transporter
P478volume96

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cites work (P2860)
Q48042620A Dynamic Protein-Protein Coupling between the TonB-Dependent Transporter FhuA and TonB.
Q36950257A TonB-dependent receptor regulates antifungal HSAF biosynthesis in Lysobacter
Q48330465A putative iron-regulated TonB-dependent receptor of Mannheimia (Pasteurella) haemolytica A1: possible mechanism for phase variation
Q35058516Acquisition of siderophores in gram-negative bacteria.
Q27635214Active transport of an antibiotic rifamycin derivative by the outer-membrane protein FhuA
Q30160202Activities of the Serratia marcescens heme receptor HasR and isolated plug and beta-barrel domains: the beta-barrel forms a heme-specific channel
Q30275526Allosteric Signaling Is Bidirectional in an Outer-Membrane Transport Protein
Q34514548Analysis of residues determining specificity of Vibrio cholerae TonB1 for its receptors
Q34992680Analysis of the Escherichia coli Tol-Pal and TonB systems by periplasmic production of Tol, TonB, colicin, or phage capsid soluble domains.
Q40597783Appropriate NR1-NR1 disulfide-linked homodimer formation is requisite for efficient expression of functional, cell surface N-methyl-D-aspartate NR1/NR2 receptors
Q33879806Bacterial heme sources: the role of heme, hemoprotein receptors and hemophores
Q29615095Bacterial iron homeostasis
Q34011314Characterization of in vitro interactions between a truncated TonB protein from Escherichia coli and the outer membrane receptors FhuA and FepA.
Q24671701Colicin biology
Q30311379Competing ligands stabilize alternate conformations of the energy coupling motif of a TonB-dependent outer membrane transporter
Q33995191Control of the ferric citrate transport system of Escherichia coli: mutations in region 2.1 of the FecI extracytoplasmic-function sigma factor suppress mutations in the FecR transmembrane regulatory protein
Q30434165Coupling of calcium and substrate binding through loop alignment in the outer-membrane transporter BtuB.
Q27631524Crystal structure of the dimeric C-terminal domain of TonB reveals a novel fold
Q27640116Crystal structures of the BtuF periplasmic-binding protein for vitamin B12 suggest a functionally important reduction in protein mobility upon ligand binding
Q30440904Crystallization and preliminary X-ray crystallographic analysis of the Escherichia coli outer membrane cobalamin transporter BtuB in complex with the carboxy-terminal domain of TonB
Q42618079Deletion and substitution analysis of the Escherichia coli TonB Q160 region.
Q43057857Deletion of the proline-rich region of TonB disrupts formation of a 2:1 complex with FhuA, an outer membrane receptor of Escherichia coli.
Q34842018Demonstration and characterization of a specific interaction between gonococcal transferrin binding protein A and TonB.
Q36576714Determination of surface-exposed, functional domains of gonococcal transferrin-binding protein A.
Q28492816Differential effects of mutations in tonB1 on intrinsic multidrug resistance and iron acquisition in Pseudomonas aeruginosa
Q30311199Differential substrate-induced signaling through the TonB-dependent transporter BtuB.
Q30165146Diffusion through channel derivatives of the Escherichia coli FhuA transport protein
Q27642759Dimerization of TonB is not essential for its binding to the outer membrane siderophore receptor FhuA of Escherichia coli
Q46847484Dual roles of the central domain of colicin D tRNase in TonB-mediated import and in immunity.
Q44688344Enhanced binding of TonB to a ligand-loaded outer membrane receptor: role of the oligomeric state of TonB in formation of a functional FhuA.TonB complex.
Q30168335Exchangeability of N termini in the ligand-gated porins of Escherichia coli
Q30165218FepA with globular domain deletions lacks activity
Q30168191FhuA barrel-cork hybrids are active transporters and receptors
Q40909411Free and hemophore-bound heme acquisitions through the outer membrane receptor HasR have different requirements for the TonB-ExbB-ExbD complex
Q41814192Gating of TonB-dependent transporters by substrate-specific forced remodelling
Q30152652Going Outside the TonB Box: Identification of Novel FepA-TonB Interactions In Vivo
Q92268257Identification and detection of iha subtypes in LEE-negative Shiga toxin-producing Escherichia coli (STEC) strains isolated from humans, cattle and food
Q30168622Identification of discrete domains within gonococcal transferrin-binding protein A that are necessary for ligand binding and iron uptake functions
Q36019137Identification of functionally important TonB-ExbD periplasmic domain interactions in vivo.
Q34470696Identification of the gene responsible for methylmalonic aciduria and homocystinuria, cblC type
Q41870719Import of the transfer RNase colicin D requires site-specific interaction with the energy-transducing protein TonB.
Q34992683Importation of nuclease colicins into E coli cells: endoproteolytic cleavage and its prevention by the immunity protein.
Q91666620In situ observation of conformational dynamics and protein ligand-substrate interactions in outer-membrane proteins with DEER/PELDOR spectroscopy
Q39887805In vivo evidence for TonB dimerization
Q39527357In vivo synthesis of the periplasmic domain of TonB inhibits transport through the FecA and FhuA iron siderophore transporters of Escherichia coli
Q39631054Induction of cell death after localization to the host cell mitochondria by the Mycobacterium tuberculosis PE_PGRS33 protein
Q42578182Interaction of TonB with the outer membrane receptor FpvA of Pseudomonas aeruginosa
Q39734949Interactions between the outer membrane ferric citrate transporter FecA and TonB: studies of the FecA TonB box.
Q36422274Interactions of the energy transducer TonB with noncognate energy-harvesting complexes
Q34922187Iron transport and signaling in Escherichia coli
Q37193615Kinetic analysis of ligand interaction with the gonococcal transferrin-iron acquisition system
Q30416370Ligand-induced structural changes in the Escherichia coli ferric citrate transporter reveal modes for regulating protein-protein interactions
Q30441392Mechanics of force propagation in TonB-dependent outer membrane transport
Q93162859Metagenomic and chemical characterization of soil cobalamin production
Q35626594Metal import through microbial membranes
Q30441351Molecular basis for substrate-dependent transmembrane signaling in an outer-membrane transporter
Q29616208Molecular basis of bacterial outer membrane permeability revisited
Q27652701Molecular characterization of the TonB2 protein from the fish pathogen Vibrio anguillarum
Q30413811Monomeric TonB and the Ton box are required for the formation of a high-affinity transporter-TonB complex.
Q30160310Multiple extracellular loops contribute to substrate binding and transport by the Escherichia coli cobalamin transporter BtuB.
Q30164589Mutant analysis of the Escherichia coli FhuA protein reveals sites of FhuA activity
Q39679960Mutational analysis of the TolA C-terminal domain of Escherichia coli and genetic evidence for an interaction between TolA and TolB.
Q30453261Mutational analysis of the TonB1 energy coupler of Pseudomonas aeruginosa
Q36969550Mutations in Escherichia coli ExbB transmembrane domains identify scaffolding and signal transduction functions and exclude participation in a proton pathway
Q43725769Mutations in the Escherichia coli receptor FepA reveal residues involved in ligand binding and transport
Q35272687Mutations in the ExbB cytoplasmic carboxy terminus prevent energy-dependent interaction between the TonB and ExbD periplasmic domains
Q58700950NMR structure of the C-terminal domain of TonB protein from
Q30157664NagA-dependent uptake of N-acetyl-glucosamine and N-acetyl-chitin oligosaccharides across the outer membrane of Caulobacter crescentus
Q40220690Neisseria gonorrhoeae requires expression of TonB and the putative transporter TdfF to replicate within cervical epithelial cells
Q30444642Observations on the calcium dependence and reversibility of cobalamin transport across the outer membrane of Escherichia coli
Q35171815Performance of standard phenotypic assays for TonB activity, as evaluated by varying the level of functional, wild-type TonB.
Q26770858ROSET Model of TonB Action in Gram-Negative Bacterial Iron Acquisition
Q33930253RcnB is a periplasmic protein essential for maintaining intracellular Ni and Co concentrations in Escherichia coli.
Q42545967Role of TonB1 in pyoverdine-mediated signaling in Pseudomonas aeruginosa
Q30306230Sequence changes in the ton box region of BtuB affect its transport activities and interaction with TonB protein
Q30160187Siderophore transport through Escherichia coli outer membrane receptor FhuA with disulfide-tethered cork and barrel domains
Q30439364Solutes modify a conformational transition in a membrane transport protein
Q27638127Structural basis of gating by the outer membrane transporter FecA
Q30157945Studies on colicin B translocation: FepA is gated by TonB.
Q30443903Substrate-dependent transmembrane signaling in TonB-dependent transporters is not conserved
Q30441272Substrate-dependent unfolding of the energy coupling motif of a membrane transport protein determined by double electron-electron resonance
Q27640766Substrate-induced transmembrane signaling in the cobalamin transporter BtuB
Q83230158Ternary structure of the outer membrane transporter FoxA with resolved signalling domain provides insights into TonB-mediated siderophore uptake
Q36019148The ExbD periplasmic domain contains distinct functional regions for two stages in TonB energization
Q30419480The N-terminal domain of a TonB-dependent transporter undergoes a reversible stepwise denaturation
Q34334962The Tol-Pal proteins of the Escherichia coli cell envelope: an energized system required for outer membrane integrity?
Q34422739The TonB dimeric crystal structures do not exist in vivo.
Q30676540The iron- and temperature-regulated cjrBC genes of Shigella and enteroinvasive Escherichia coli strains code for colicin Js uptake
Q34110000Tol-dependent macromolecule import through the Escherichia coli cell envelope requires the presence of an exposed TolA binding motif.
Q37860145TonB or not TonB: is that the question?
Q30362887TonB system, in vivo assays and characterization.
Q30165118TonB-dependent receptors-structural perspectives

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