High Leucine Diets Stimulate Cerebral Branched-Chain Amino Acid Degradation and Modify Serotonin and Ketone Body Concentrations in a Pig Model

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High Leucine Diets Stimulate Cerebral Branched-Chain Amino Acid Degradation and Modify Serotonin and Ketone Body Concentrations in a Pig Model is …
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P819ADS bibcode2016PLoSO..1150376W
P356DOI10.1371/JOURNAL.PONE.0150376
P8608Fatcat IDrelease_lgehy2f76bcyxgf7j7q7bvxyom
P932PMC publication ID4773154
P698PubMed publication ID26930301
P5875ResearchGate publication ID296624442

P50authorAlexandra SchutkowskiQ47169064
P2093author name stringBettina König
Frank Hirche
Gabriele I Stangl
Holger Kluge
Etienne Corrent
Andreas Kiowski
Anna G Wessels
Jörg Bartelt
P2860cites workDeproteinization techniques for HPLC amino acid analysis in fresh pork muscle and dry-cured hamQ58477891
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Determination of branched-chain alpha-keto acid dehydrogenase activity state and branched-chain alpha-keto acid dehydrogenase kinase activity and protein in mammalian tissuesQ74318097
5-Hydroxytryptamine (serotonin) in the gastrointestinal tractQ26829448
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Therapeutic use of branched-chain amino acids in burn, trauma, and sepsisQ36347165
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Postprandial muscle protein synthesis is higher after a high whey protein, leucine-enriched supplement than after a dairy-like product in healthy older people: a randomized controlled trialQ37539874
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Leucine stimulates mammalian target of rapamycin signaling in C2C12 myoblasts in part through inhibition of adenosine monophosphate-activated protein kinaseQ40193113
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Leucine regulates translation of specific mRNAs in L6 myoblasts through mTOR-mediated changes in availability of eIF4E and phosphorylation of ribosomal protein S6.Q40960220
Supplementing L-leucine to a low-protein diet increases tissue protein synthesis in weanling pigsQ43062070
The effects of branched-chain amino acid interactions on growth performance, blood metabolites, enzyme kinetics and transcriptomics in weaned pigs.Q43144937
Chronic administration of branched-chain amino acids impairs spatial memory and increases brain-derived neurotrophic factor in a rat modelQ44233381
Specific dietary selection for tryptophan by the pigletQ44840734
Physiological rise in plasma leucine stimulates muscle protein synthesis in neonatal pigs by enhancing translation initiation factor activationQ45219972
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Uncharged tRNA and sensing of amino acid deficiency in mammalian piriform cortex.Q46386380
A molecular model of human branched-chain amino acid metabolismQ46762438
Effects of a high-protein ketogenic diet on hunger, appetite, and weight loss in obese men feeding ad libitumQ47253645
Interactive effects of dietary levels of tryptophan and protein on voluntary feed intake and growth performance in pigs, in relation to plasma free amino acids and hypothalamic serotonin1Q48470957
Potential anxiolytic properties of R-(+)-8-OSO2CF3-PAT, a 5-HT 1A receptor agonist.Q49113191
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectserotoninQ167934
P304page(s)e0150376
P577publication date2016-03-01
P1433published inPLOS OneQ564954
P1476titleHigh Leucine Diets Stimulate Cerebral Branched-Chain Amino Acid Degradation and Modify Serotonin and Ketone Body Concentrations in a Pig Model
P478volume11