Beta-defensin 2 enhances immunogenicity and protection of an adenovirus-based H5N1 influenza vaccine at an early time

scientific article

Beta-defensin 2 enhances immunogenicity and protection of an adenovirus-based H5N1 influenza vaccine at an early time is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.VIRUSRES.2013.09.013
P932PMC publication ID3919024
P698PubMed publication ID24051000

P50authorJacqueline M. KatzQ87082629
Ruben O DonisQ87441189
Suryaprakash SambharaQ104742683
Suresh K MittalQ104783680
Sai V VemulaQ114722175
P2093author name stringOmar Amen
P2860cites workImpact of preexisting adenovirus vector immunity on immunogenicity and protection conferred with an adenovirus-based H5N1 influenza vaccineQ21134724
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Roles of antimicrobial peptides such as defensins in innate and adaptive immunityQ24675023
Mediators of innate immunity that target immature, but not mature, dendritic cells induce antitumor immunity when genetically fused with nonimmunogenic tumor antigensQ28206241
Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferretsQ29619972
Production of adenovirus vectors and their use as a delivery system for influenza vaccinesQ30226988
Bovine adenoviral vector-based H5N1 influenza vaccine overcomes exceptionally high levels of pre-existing immunity against human adenovirusQ30229074
Heterosubtypic immunity against human influenza A viruses, including recently emerged avian H5 and H9 viruses, induced by FLU-ISCOM vaccine in mice requires both cytotoxic T-lymphocyte and macrophage functionQ30233581
New pre-pandemic influenza vaccines: an egg- and adjuvant-independent human adenoviral vector strategy induces long-lasting protective immune responses in mice.Q30365380
A broadly protective vaccine against globally dispersed clade 1 and clade 2 H5N1 influenza viruses.Q30369294
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In situ tumor vaccination with adenovirus vectors encoding measles virus fusogenic membrane proteins and cytokinesQ30832171
Attraction and activation of dendritic cells at the site of tumor elicits potent antitumor immunityQ33713956
Protective CD4+ and CD8+ T cells against influenza virus induced by vaccination with nucleoprotein DNAQ33785071
β-defensin 2 as an adjuvant promotes anti-melanoma immune responses and inhibits the growth of implanted murine melanoma in vivoQ34163480
Mammalian defensins in immunity: more than just microbicidalQ34647756
Improved vaccine protection against retrovirus infection after co-administration of adenoviral vectors encoding viral antigens and type I interferon subtypesQ35353052
Codelivery of the chemokine CCL3 by an adenovirus-based vaccine improves protection from retrovirus infection.Q35689651
Defensin participation in innate and adaptive immunityQ36990379
Adenoviral vector expressing murine β-defensin 2 enhances immunogenicity of an adenoviral vector based H5N1 influenza vaccine in aged miceQ37331004
Influenza A virus nucleoprotein is a major target antigen for cross-reactive anti-influenza A virus cytotoxic T lymphocytesQ37680808
Development and characterization of bovine x human hybrid cell lines that efficiently support the replication of both wild-type bovine and human adenoviruses and those with E1 deletedQ39683618
Recombinant mouse beta-defensin 2 inhibits infection by influenza A virus by blocking its entryQ39733468
Expression of mouse beta-defensin-3 in MDCK cells and its anti-influenza-virus activityQ39870557
Decreased tumorigenic potential of EphA2-overexpressing breast cancer cells following treatment with adenoviral vectors that express EphrinA1.Q40516862
Genetic fusions with viral chemokines target delivery of nonimmunogenic antigen to trigger antitumor immunity independent of chemotaxisQ40568230
Toll-like receptor 4-dependent activation of dendritic cells by beta-defensin 2.Q40692879
Induction of TLR4-dependent CD8+ T cell immunity by murine β-defensin2 fusion protein vaccinesQ45188786
Evaluation of a genetically modified reassortant H5N1 influenza A virus vaccine candidate generated by plasmid-based reverse genetics.Q45729695
DNA vaccines encoding human immunodeficiency virus-1 glycoprotein 120 fusions with proinflammatory chemoattractants induce systemic and mucosal immune responsesQ45731543
Acceleration of influenza virus clearance by Th1 cells in the nasal site of mice immunized intranasally with adjuvant-combined recombinant nucleoprotein.Q45771024
A novel mouse beta defensin, Defb2, which is upregulated in the airways by lipopolysaccharide.Q47991688
Genetic fusion of chemokines to a self tumor antigen induces protective, T-cell dependent antitumor immunityQ74649982
P433issue2
P921main subjectinfluenza vaccineQ383260
AdenoviridaeQ193447
P304page(s)398-403
P577publication date2013-09-17
P1433published inVirus ResearchQ15749215
P1476titleBeta-defensin 2 enhances immunogenicity and protection of an adenovirus-based H5N1 influenza vaccine at an early time
P478volume178

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cites work (P2860)
Q56901675A Bovine Adenoviral Vector-Based H5N1 Influenza -Vaccine Provides Enhanced Immunogenicity and Protection at a Significantly Low Dose
Q40093625Foreign gene expression and induction of antibody response by recombinant fowl adenovirus-9-based vectors with exogenous promoters
Q90461228Immunologic Dose-Response to Adenovirus-Vectored Vaccines in Animals and Humans: A Systematic Review of Dose-Response Studies of Replication Incompetent Adenoviral Vaccine Vectors when Given via an Intramuscular or Subcutaneous Route
Q30369109Intranasal immunization of recombinant Lactococcus lactis induces protection against H5N1 virus in ferrets.
Q89514236Porcine β-defensin 2 inhibits proliferation of pseudorabies virus in vitro and in transgenic mice
Q47557198Towards the Application of Human Defensins as Antivirals
Q50111769Β-defensins - Underestimated peptides in influenza combat

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