Genomic science in understanding cholera outbreaks and evolution of Vibrio cholerae as a human pathogen.

scientific article

Genomic science in understanding cholera outbreaks and evolution of Vibrio cholerae as a human pathogen. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1007/82_2014_366
P932PMC publication ID4153709
P698PubMed publication ID24590676

P2093author name stringJohn J Mekalanos
William P Robins
P2860cites workDNA sequence of both chromosomes of the cholera pathogen Vibrio choleraeQ22122394
Comparative analysis of superintegrons: engineering extensive genetic diversity in the VibrionaceaeQ24561864
Type IV pilin structure and assembly: X-ray and EM analyses of Vibrio cholerae toxin-coregulated pilus and Pseudomonas aeruginosa PAK pilinQ27641330
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Filamentous phages linked to virulence of Vibrio choleraeQ28180172
The origin of the Haitian cholera outbreak strainQ28300132
TcpP protein is a positive regulator of virulence gene expression in Vibrio choleraeQ28485708
Toxin-co-regulated pilus cluster in non-O1, non-toxigenic Vibrio cholerae: evidence of a third allele of pilin geneQ47988516
TcpA pilin sequences and colonization requirements for O1 and O139 vibrio choleraeQ48079581
Biotype-specific tcpA genes in Vibrio choleraeQ48080591
Peru-15, a live attenuated oral cholera vaccine, is safe and immunogenic in Bangladeshi toddlers and infants.Q53588316
Single amino acid substitutions in the N-terminus of Vibrio cholerae TcpA affect colonization, autoagglutination, and serum resistance.Q54162990
Structural basis for broad DNA-specificity in integron recombinationQ56899134
Physical and genetic map of the genome of Vibrio parahaemolyticus: presence of two chromosomes in Vibrio speciesQ61794405
Phenotypic and genetic characterization of Vibrio cholerae O1 clinical isolates collected through national antimicrobial resistance surveillance network in NepalQ61856728
Delineation of pilin domains required for bacterial association into microcolonies and intestinal colonization by Vibrio choleraeQ64449713
A search for cholera toxin (CT), toxin coregulated pilus (TCP), the regulatory element ToxR and other virulence factors in non-01/non-0139 Vibrio choleraeQ64449985
Duplication and amplification of toxin genes in Vibrio choleraeQ71063547
Expression of cholera toxin B subunit in transgenic tomato plantsQ78529703
Phenotypic and genetic analyses of 111 clinical and environmental O1, O139, and non-O1/O139 Vibrio cholerae strains from different geographical areasQ82459532
Genome-wide study of the defective sucrose fermenter strain of Vibrio cholerae from the Latin American cholera epidemicQ28729188
A recalibrated molecular clock and independent origins for the cholera pandemic clonesQ28756125
Genome-scale approaches to resolving incongruence in molecular phylogeniesQ29547249
Evolutionary relationships of pathogenic clones of Vibrio cholerae by sequence analysis of four housekeeping genesQ30312630
Comparative genomic analysis of Vibrio cholerae: genes that correlate with cholera endemic and pandemic disease.Q30329522
New variants of Vibrio cholerae O1 biotype El Tor with attributes of the classical biotype from hospitalized patients with acute diarrhea in BangladeshQ30331626
Genetic characteristics of Matlab variants of Vibrio cholerae O1 that are hybrids between classical and El Tor biotypes.Q30357315
Use of chromosomal integron arrays as a phylogenetic typing system for Vibrio cholerae pandemic strains.Q30361328
Genetic diversity of toxigenic and nontoxigenic Vibrio cholerae serogroups O1 and O139 revealed by array-based comparative genomic hybridizationQ30361355
Distribution of genes for virulence and ecological fitness among diverse Vibrio cholerae population in a cholera endemic area: tracking the evolution of pathogenic strains.Q30369287
Peruvian Vibrio cholerae O1 El Tor strains possess a distinct region in the Vibrio seventh pandemic island-II that differentiates them from the prototype seventh pandemic El Tor strains.Q30374878
Comparative genomics reveals mechanism for short-term and long-term clonal transitions in pandemic Vibrio cholerae.Q30380277
Genome sequence of hybrid Vibrio cholerae O1 MJ-1236, B-33, and CIRS101 and comparative genomics with V. choleraeQ30387356
Evolution of seventh cholera pandemic and origin of 1991 epidemic, Latin AmericaQ30390859
Evidence for several waves of global transmission in the seventh cholera pandemicQ30406370
Structural variation of the superintegron in the toxigenic Vibrio cholerae O1 El Tor.Q30413522
Multi-locus variable number tandem repeat analysis of 7th pandemic Vibrio choleraeQ30417198
The Molecular Epidemiology of Cholera in Latin AmericaQ30417930
Molecular evolution of the seventh-pandemic clone of Vibrio cholerae and its relationship to other pandemic and epidemic V. cholerae isolatesQ30419835
Structure of the Vibrio cholerae Type IVb Pilus and stability comparison with the Neisseria gonorrhoeae type IVa pilusQ30419868
Spatio-temporal dynamics of cholera during the first year of the epidemic in HaitiQ30429500
Use of in vivo-induced antigen technology (IVIAT) to identify genes uniquely expressed during human infection with Vibrio choleraeQ31147722
A Statistical Approach to the Epidemiology of Cholera in Madras PresidencyQ33766740
Self-limiting nature of seasonal cholera epidemics: Role of host-mediated amplification of phageQ33771191
Clinical and environmental isolates of Vibrio cholerae serogroup O141 carry the CTX phage and the genes encoding the toxin-coregulated piliQ33974053
Molecular analysis of Vibrio cholerae O1, O139, non-O1, and non-O139 strains: clonal relationships between clinical and environmental isolatesQ33988961
Genotypes associated with virulence in environmental isolates of Vibrio choleraeQ33989564
Analysis of an autoregulatory loop controlling ToxT, cholera toxin, and toxin-coregulated pilus production in Vibrio choleraeQ33991807
RNA-Seq-based monitoring of infection-linked changes in Vibrio cholerae gene expression.Q33993574
Characterization of VPI pathogenicity island and CTXphi prophage in environmental strains of Vibrio choleraeQ34011461
A hybrid approach for the automated finishing of bacterial genomesQ34032597
Lysogenic conversion by a filamentous phage encoding cholera toxinQ34062735
Evolutionary and functional analyses of variants of the toxin-coregulated pilus protein TcpA from toxigenic Vibrio cholerae non-O1/non-O139 serogroup isolatesQ34132602
Satellite phage TLCφ enables toxigenic conversion by CTX phage through dif site alteration.Q34143438
The Vibrio cholerae ToxR/TcpP/ToxT virulence cascade: distinct roles for two membrane-localized transcriptional activators on a single promoterQ38307608
Molecular analysis of rugosity in a Vibrio cholerae O1 El Tor phase variantQ38339427
A satellite phage-encoded antirepressor induces repressor aggregation and cholera toxin gene transferQ39647882
TcpH influences virulence gene expression in Vibrio cholerae by inhibiting degradation of the transcription activator TcpP.Q40534708
Cholera due to altered El Tor strains of Vibrio cholerae O1 in BangladeshQ41067202
A bacteriophage encoding a pathogenicity island, a type-IV pilus and a phage receptor in cholera bacteria.Q41482707
The gene encoding the heat-stable enterotoxin of Vibrio cholerae is flanked by 123-base pair direct repeatsQ41504394
Structural inferences for Cholera toxin mutations in Vibrio choleraeQ41865473
Virulence and the environment: a novel role for Vibrio cholerae toxin-coregulated pili in biofilm formation on chitinQ42092038
Complete genome sequence of a sucrose-nonfermenting epidemic strain of Vibrio cholerae O1 from Brazil.Q42152546
On the origins of a Vibrio speciesQ42213027
Non-O1 Vibrio cholerae unlinked to cholera in HaitiQ42374402
Cholera in Mozambique, variant of Vibrio choleraeQ42541007
VlpA of Vibrio cholerae O1: the first bacterial member of the alpha 2-microglobulin lipocalin superfamilyQ42659197
Regulation, replication, and integration functions of the Vibrio cholerae CTXphi are encoded by region RS2.Q42660232
Replication and integration of a Vibrio cholerae cryptic plasmid linked to the CTX prophageQ42681743
Environmental factors influencing epidemic choleraQ42838003
Transcriptional profiling of Vibrio cholerae recovered directly from patient specimens during early and late stages of human infectionQ42957120
Classical ctxB in Vibrio cholerae O1, Kolkata, IndiaQ43144512
Construction of a recombinant live oral vaccine from a non-toxigenic strain of Vibrio cholerae O1 serotype inaba biotype E1 Tor and assessment of its reactogenicity and immunogenicity in the rabbit modelQ43338204
A Vibrio cholerae serogroup O1 vaccine candidate against CTX ET Phi infectionQ44533423
Nepalese origin of cholera epidemic in HaitiQ34268765
Evolutionary dynamics of Vibrio cholerae O1 following a single-source introduction to HaitiQ34355034
High depth, whole-genome sequencing of cholera isolates from Haiti and the Dominican Republic.Q34410299
A distinctive class of integron in the Vibrio cholerae genome.Q34465137
A colonization factor links Vibrio cholerae environmental survival and human infectionQ34474848
Chitin induces natural competence in Vibrio choleraeQ34476987
The Vibrio cholerae genome contains two unique circular chromosomes.Q34481163
Cholera toxin production by the El Tor variant of Vibrio cholerae O1 compared to prototype El Tor and classical biotypesQ34489318
Cholera and climate: revisiting the quantitative evidenceQ34552851
Evidence of a dominant lineage of Vibrio cholerae-specific lytic bacteriophages shed by cholera patients over a 10-year period in Dhaka, BangladeshQ34565895
Modeling the role of bacteriophage in the control of cholera outbreaksQ34574901
Building phylogenetic trees from molecular data with MEGA.Q34619723
CMG-biotools, a free workbench for basic comparative microbial genomics.Q34663646
Comparative genomic analyses of the vibrio pathogenicity island and cholera toxin prophage regions in nonepidemic serogroup strains of Vibrio choleraeQ34765878
Examination of diverse toxin-coregulated pilus-positive Vibrio cholerae strains fails to demonstrate evidence for Vibrio pathogenicity island phage.Q35011631
Population genetics of Vibrio cholerae from Nepal in 2010: evidence on the origin of the Haitian outbreakQ35187011
Characterization of Vibrio cholerae O1 El Tor biotype variant clinical isolates from Bangladesh and Haiti, including a molecular genetic analysis of virulence genesQ35530669
Pathogenicity islands and phages in Vibrio cholerae evolution.Q35579485
A new type of conjugative transposon encodes resistance to sulfamethoxazole, trimethoprim, and streptomycin in Vibrio cholerae O139.Q35609627
Drug-resistance mechanisms in Vibrio cholerae O1 outbreak strain, Haiti, 2010.Q35847243
Comparative genomics of Vibrio cholerae from Haiti, Asia, and AfricaQ35847274
Characterization of toxigenic Vibrio cholerae from Haiti, 2010-2011.Q35847286
Recent clonal origin of cholera in HaitiQ36039635
Construction and Evaluation of a Safe, Live, Oral Vibrio cholerae Vaccine Candidate, IEM108Q36045133
Genomic diversity of 2010 Haitian cholera outbreak strainsQ36122809
Identification of toxS, a regulatory gene whose product enhances toxR-mediated activation of the cholera toxin promoterQ36174807
Toxin, toxin-coregulated pili, and the toxR regulon are essential for Vibrio cholerae pathogenesis in humansQ36355455
Epidemic cholera in Ecuador: multidrug-resistance and transmission by water and seafoodQ36504105
CTXphi immunity: application in the development of cholera vaccinesQ36506802
Characterization of Vibrio cgolerae non-O1 serogroups obtained from an outbreak of diarrhea in Lima, Peru.Q36525462
Novel cholix toxin variants, ADP-ribosylating toxins in Vibrio cholerae non-O1/non-O139 strains, and their pathogenicityQ36558763
Genetic diversity and virulence potential of environmental Vibrio cholerae population in a cholera-endemic areaQ36604953
Genome Sequences of Clinical Vibrio cholerae Isolates from an Oyster-Borne Cholera Outbreak in FloridaQ37333902
P921main subjectVibrio choleraeQ160821
genomicsQ222046
choleraQ12090
P304page(s)211-229
P577publication date2014-01-01
P1433published inCurrent Topics in Microbiology and ImmunologyQ15752446
P1476titleGenomic science in understanding cholera outbreaks and evolution of Vibrio cholerae as a human pathogen.
P478volume379

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