Advances in multicellular spheroids formation

scientific article

Advances in multicellular spheroids formation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1098/RSIF.2016.0877
P8608Fatcat IDrelease_dtyz4hhj4nhgnc4s4tmfeeuriu
P932PMC publication ID5332573
P698PubMed publication ID28202590

P50authorHu ZhangQ51222770
Xiaolin CuiQ63993141
Yusak HartantoQ89029053
P2093author name stringX Cui
P2860cites workOpportunities and challenges for use of tumor spheroids as models to test drug delivery and efficacyQ26826863
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The role of actin filaments and microtubules in hepatocyte spheroid self-assemblyQ32063631
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Enhanced percolation and gene expression in tumor hypoxia by PEGylated polyplex micelles.Q33713888
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Apoptosis, cell adhesion and the extracellular matrix in the three-dimensional growth of multicellular tumor spheroidsQ34060908
Detailed interrogation of trypanosome cell biology via differential organelle staining and automated image analysisQ34116382
Method for the determination of oxygen consumption rates and diffusion coefficients in multicellular spheroidsQ34534929
Differentiation of human embryonic stem cells into hepatocytes in 2D and 3D culture systems in vitroQ34554834
3D cell culture: a review of current approaches and techniquesQ34624917
Curcumin potentiates antitumor activity of 5-fluorouracil in a 3D alginate tumor microenvironment of colorectal cancerQ35605606
Development of poly(ethylene glycol) hydrogels for salivary gland tissue engineering applications.Q35667345
Cell adhesion and signalling by cadherins and Ig-CAMs in cancerQ35667465
Droplet-based microfluidic system to form and separate multicellular spheroids using magnetic nanoparticlesQ46515782
Microscopic images of intraspheroidal pH by 1H magnetic resonance chemical shift imaging of pH sensitive indicators.Q46835845
Three-dimensional axisymmetric flow-focusing device using stereolithographyQ47235127
Effect of particle size in a colloidal hydrogel scaffold for 3D cell cultureQ47344152
Concave microwell based size-controllable hepatosphere as a three-dimensional liver tissue modelQ47362910
Developing multi-cellular tumor spheroid model (MCTS) in the chitosan/collagen/alginate (CCA) fibrous scaffold for anticancer drug screeningQ50203846
Mass transfer and metabolic reactions in hepatocyte spheroids cultured in rotating wall gas-permeable membrane system.Q50908267
Tumor engineering: orthotopic cancer models in mice using cell-loaded, injectable, cross-linked hyaluronan-derived hydrogels.Q50974234
Tissue engineering with electric fields: immobilization of mammalian cells in multilayer aggregates using dielectrophoresis.Q51038683
Cell patterning using magnetite nanoparticles and magnetic force.Q51084742
Superhydrophobic chips for cell spheroids high-throughput generation and drug screening.Q51515213
Mixed hydrogel bead-based tumor spheroid formation and anticancer drug testing.Q51518504
An oxygen-permeable spheroid culture system for the prevention of central hypoxia and necrosis of spheroids.Q51537494
Diffusion-mediated in situ alginate encapsulation of cell spheroids using microscale concave well and nanoporous membrane.Q51551160
Spheroid formation and differentiation into hepatocyte-like cells of rat mesenchymal stem cell induced by co-culture with liver cells.Q53540825
The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini.Q53956406
Design of an artificial skin. Part III. Control of pore structure.Q53960005
A heterologous 3-D coculture model of breast tumor cells and fibroblasts to study tumor-associated fibroblast differentiation.Q55034791
Relations between pH, oxygen partial pressure and growth in cultured cell spheroids.Q55485938
A Non-Mulberry Silk Fibroin Protein Based 3D In Vitro Tumor Model for Evaluation of Anticancer Drug ActivityQ57173489
Chitosan as inter-cellular linker to accelerate multicellular spheroid generation in hydrogel scaffoldQ57356251
Thermoreversible Hydrogel for In Situ Generation and Release of HepG2 SpheroidsQ57359588
Monodisperse Cell-Encapsulating Peptide Microgel Beads for 3D Cell CultureQ63989811
A simplified method for production and growth of multicellular tumor spheroidsQ67684815
Morphological and immuno-cytochemical characterization of a hetero-spheroid composed of fibroblasts and hepatocytesQ68040809
A Multi-component Radiation Survival Curve Using anin VitroTumour ModelQ71154062
Three-dimensional fibroblast-tumor cell interaction causes downregulation of RACK1 mRNA expression in breast cancer cells in vitroQ78387458
Reconstruction of 3D stacked hepatocyte tissues using degradable, microporous poly(d,l-lactide-co-glycolide) membranesQ83212243
Three-dimensional in vitro tissue culture models of breast cancer-- a review.Q35757595
Pannexin1 drives multicellular aggregate compaction via a signaling cascade that remodels the actin cytoskeletonQ35868295
Development of complex-shaped liver multicellular spheroids as a human-based model for nanoparticle toxicity assessment in vitroQ35908689
Three-dimensional type I collagen cell culture systems for the study of bone pathophysiologyQ36007408
Soft fibrin gels promote selection and growth of tumorigenic cells.Q36117097
Three-dimensional tissue culture models in cancer biologyQ36173561
Brave little world: spheroids as an in vitro model to study tumor-immune-cell interactionsQ36438583
Three-dimensional polymeric systems for cancer cell studiesQ36495645
Directed assembly of cell-laden microgels for fabrication of 3D tissue constructsQ36775306
Modeling Ewing sarcoma tumors in vitro with 3D scaffoldsQ36782138
3D Porous Chitosan-Alginate Scaffolds as an In Vitro Model for Evaluating Nanoparticle-Mediated Tumor Targeting and Gene Delivery to Prostate CancerQ36798100
Modeling tumor microenvironments using custom-designed biomaterial scaffoldsQ36857398
Wnt signaling is required for organization of the lens fiber cell cytoskeleton and development of lens three-dimensional architectureQ37118005
Rapid formation of size-controllable multicellular spheroids via 3D acoustic tweezers.Q37127381
Microfluidic system for formation of PC-3 prostate cancer co-culture spheroidsQ37173989
Recent advances in three-dimensional multicellular spheroid culture for biomedical researchQ37195879
Novel multicellular organotypic models of normal and malignant breast: tools for dissecting the role of the microenvironment in breast cancer progressionQ37205530
Thick-tissue bioreactor as a platform for long-term organotypic culture and drug deliveryQ37305892
Organ printing: tissue spheroids as building blocksQ37379489
A fully defined and scalable 3D culture system for human pluripotent stem cell expansion and differentiationQ37421348
Hyaluronic acid-based hydrogels as 3D matrices for in vitro evaluation of chemotherapeutic drugs using poorly adherent prostate cancer cells.Q37435382
beta4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epitheliumQ37460431
Strategies for directing the structure and function of three-dimensional collagen biomaterials across length scalesQ37627073
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3D tumour models: novel in vitro approaches to cancer studiesQ37866146
In vitro three-dimensional (3D) models in cancer research: an updateQ37967634
Microfluidic encapsulation of cells in polymer microgelsQ37999003
Cell encapsulation via microtechnologiesQ38179619
Hydrogels for 3D mammalian cell culture: a starting guide for laboratory practiceQ38272482
The effect of static magnetic fields on the aggregation and cytotoxicity of magnetic nanoparticlesQ38470486
3D scaffolds in breast cancer research.Q38687086
Fibroblast spheroids as a model to study sustained fibroblast quiescence and their crosstalk with tumor cellsQ38771074
Three-dimensional culture systems in cancer research: Focus on tumor spheroid modelQ38803945
A practical guide to hydrogels for cell cultureQ38819764
In-situ birth of MSCs multicellular spheroids in poly(L-glutamic acid)/chitosan scaffold for hyaline-like cartilage regenerationQ38969501
A microfluidic-based platform for tumour spheroid culture, monitoring and drug screeningQ38998051
Galactosylated reversible hydrogels as scaffold for HepG2 spheroid generation.Q39037938
The dissociation and aggregation of cells from organ rudiments of the early chick embryoQ39388304
Elucidating the mechanobiology of malignant brain tumors using a brain matrix-mimetic hyaluronic acid hydrogel platformQ39494266
Multicellular tumor spheroids as an in vivo-like tumor model for three-dimensional imaging of chemotherapeutic and nano material cellular penetrationQ39533609
A multicellular spheroid formation and extraction chip using removable cell trapping barriersQ39637627
Fabrication of a modular tissue construct in a microfluidic chipQ39989181
Diversity of cell-mediated adhesions in breast cancer spheroids.Q40056404
Engineering tumors with 3D scaffoldsQ40085983
Rapid generation of single-tumor spheroids for high-throughput cell function and toxicity analysisQ40231706
Design of custom-shaped vascularized tissues using microtissue spheroids as minimal building unitsQ40289114
Dynamic analysis of hepatoma spheroid formation: roles of E-cadherin and beta1-integrinQ40314002
The origin of the myofibroblasts in breast cancer. Recapitulation of tumor environment in culture unravels diversity and implicates converted fibroblasts and recruited smooth muscle cellsQ40342271
Role of complex cadherins in cell-cell adhesion evaluated by spheroid formation in renal cell carcinoma cell lines.Q40600074
Method for generation of homogeneous multicellular tumor spheroids applicable to a wide variety of cell typesQ40644738
Fibronectin matrix assembly regulates alpha5beta1-mediated cell cohesionQ40648245
Cellular changes involved in conversion of normal to malignant breast: importance of the stromal reactionQ40964604
A Novel Core-Shell Microcapsule for Encapsulation and 3D Culture of Embryonic Stem CellsQ41188345
Human mesenchymal stem cell spheroids in fibrin hydrogels exhibit improved cell survival and potential for bone healingQ41954071
Cell-enclosing gelatin-based microcapsule production for tissue engineering using a microfluidic flow-focusing systemQ42100010
Encapsulation of adipose stromal vascular fraction cells in alginate hydrogel spheroids using a direct-write three-dimensional printing systemQ42185851
Influence of pancreatic islets on spheroid formation and functions of hepatocytes in hepatocyte-pancreatic islet spheroid cultureQ42467444
Integration of endothelial cells in multicellular spheroids prevents apoptosis and induces differentiationQ42549775
Three-Dimensional Neural Spheroid Culture: An In Vitro Model for Cortical StudiesQ42636669
Hydrogel thin film with swelling-induced wrinkling patterns for high-throughput generation of multicellular spheroids.Q42798670
Micromolding of photocrosslinkable hyaluronic acid for cell encapsulation and entrapmentQ42800004
Three-dimensional co-culture of rat hepatocyte spheroids and NIH/3T3 fibroblasts enhances hepatocyte functional maintenance.Q42802027
Molding cell beads for rapid construction of macroscopic 3D tissue architectureQ42813943
Cell-sized condensed collagen microparticles for preparing microengineered composite spheroids of primary hepatocytesQ42823671
Application of open porous poly(D,L-lactide-co-glycolide) microspheres and the strategy of hydrophobic seeding in hepatic tissue cultivationQ42824487
Microarrays for the scalable production of metabolically relevant tumour spheroids: a tool for modulating chemosensitivity traits.Q44439189
Development of co-culture system of hepatocytes with bone marrow cells for expression and maintenance of hepatic functions.Q44828038
Adhesion-mediated signal transduction in human articular chondrocytes: the influence of biomaterial chemistry and tenascin-C.Q45142294
Three-dimensional growth patterns of various human tumor cell lines in simulated microgravity of a NASA bioreactorQ45294496
Structural polarity and functional bile canaliculi in rat hepatocyte spheroidsQ45713503
Monodisperse semi-permeable microcapsules for continuous observation of cells.Q45928153
P433issue127
P921main subjectmulticellularityQ110243984
P577publication date2017-02-01
P1433published inJournal of the Royal Society InterfaceQ2492390
P1476titleAdvances in multicellular spheroids formation
P478volume14