Structural details of the OxyR peroxide-sensing mechanism

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Structural details of the OxyR peroxide-sensing mechanism is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2015PNAS..112.6443J
P356DOI10.1073/PNAS.1424495112
P932PMC publication ID4443364
P698PubMed publication ID25931525
P5875ResearchGate publication ID277360446

P50authorInseong JoQ51152128
You-Hee ChoQ73348533
P2093author name stringNam-Chul Ha
Jin-Sik Kim
Saemee Song
In-Young Chung
Hee-Won Bae
P2860cites workA new and rapid colorimetric determination of acetylcholinesterase activityQ26778487
Structural basis of the redox switch in the OxyR transcription factorQ27631186
Crystal structure of peroxiredoxin from Aeropyrum pernix K1 complexed with its substrate, hydrogen peroxideQ27657747
The structure of a reduced form of OxyR from Neisseria meningitidisQ27661691
Structural Evidence that Peroxiredoxin Catalytic Power Is Based on Transition-State StabilizationQ27663573
Structures of thePorphyromonas gingivalisOxyR regulatory domain explain differences in expression of the OxyR regulon inEscherichia coliandP. gingivalisQ27680170
Coot: model-building tools for molecular graphicsQ27860505
Overview of the CCP4 suite and current developmentsQ27860782
The major catalase gene (katA) of Pseudomonas aeruginosa PA14 is under both positive and negative control of the global transactivator OxyR in response to hydrogen peroxideQ28492604
OxyR regulated the expression of two major catalases, KatA and KatB, along with peroxiredoxin, AhpC in Pseudomonas putidaQ29346845
Molecular biology of the LysR family of transcriptional regulatorsQ29615198
Cellular defenses against superoxide and hydrogen peroxideQ29615306
Mutational analysis of the redox-sensitive transcriptional regulator OxyR: regions important for DNA binding and multimerizationQ30452531
Redox regulation of OxyR requires specific disulfide bond formation involving a rapid kinetic reaction pathQ31127419
Improved low-resolution crystallographic refinement with Phenix and RosettaQ33978661
Thiol-based redox switches and gene regulationQ35040525
Peroxide-sensing transcriptional regulators in bacteriaQ36281008
Regulation of the OxyR transcription factor by hydrogen peroxide and the cellular thiol-disulfide statusQ37199804
Bacterial defenses against oxidative stressQ37570468
Redox-dependent shift of OxyR-DNA contacts along an extended DNA-binding site: a mechanism for differential promoter selectionQ38304435
Mutational analysis of Pseudomonas aeruginosa OxyR to define the regions required for peroxide resistance and acute virulenceQ45197288
Differential roles of OxyR-controlled antioxidant enzymes alkyl hydroperoxide reductase (AhpCF) and catalase (KatB) in the protection of Pseudomonas aeruginosa against hydrogen peroxide in biofilm vs. planktonic culture.Q47760451
A general method for rapid site-directed mutagenesis using the polymerase chain reaction.Q48247178
Factors affecting protein thiol reactivity and specificity in peroxide reductionQ83579737
P433issue20
P407language of work or nameEnglishQ1860
P304page(s)6443-6448
P577publication date2015-04-30
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleStructural details of the OxyR peroxide-sensing mechanism
P478volume112

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cites work (P2860)
Q52682442A Novel Tetrameric Assembly Configuration in VV2_1132, a LysR-Type Transcriptional Regulator in Vibrio vulnificus.
Q95314983A dual attack on the peroxide bond. The common principle of peroxidatic cysteine or selenocysteine residues
Q48172391Activation of leuO by LrhA in Escherichia coli
Q47763123Amino acid residues critical for DNA binding and inducer recognition in CbnR, a LysR-type transcriptional regulator from Cupriavidus necator NH9.
Q88918474Cell-Wall Recycling of the Gram-Negative Bacteria and the Nexus to Antibiotic Resistance
Q47389167Characterization of redox-active cysteine residues of persulfide-responsive transcriptional repressor SqrR.
Q92655481Characterization of the pleiotropic LysR-type transcription regulator LeuO of Escherichia coli
Q38634845Conferring specificity in redox pathways by enzymatic thiol/disulfide exchange reactions.
Q49568129Coordinating carbon and nitrogen metabolic signaling through the cyanobacterial global repressor NdhR.
Q48200830Crystal structure of peroxiredoxin 3 from Vibrio vulnificus and its implications for scavenging peroxides and nitric oxide
Q39387054Cysteines as Redox Molecular Switches and Targets of Disease
Q58615361DbdR, a new member of the LysR family of transcriptional regulators, coordinately controls four promoters in the AR-1 3,5-dihydroxybenzoate anaerobic degradation pathway
Q48524463Defining the binding determinants of Shewanella oneidensis OxyR: implications for the link between the contracted OxyR regulon and adaptation
Q58749692Discovery of as a Global Regulator of Environmental Adaptation and Virulence in
Q38924604Discrimination and Integration of Stress Signals by Pathogenic Bacteria.
Q37153801Dual promoters of the major catalase (KatA) govern distinct survival strategies of Pseudomonas aeruginosa
Q55409105Functional Mechanism of the Efflux Pumps Transcription Regulators From Pseudomonas aeruginosa Based on 3D Structures.
Q92482137Glutathione Activates Type III Secretion System Through Vfr in Pseudomonas aeruginosa
Q55396456Mechanistic studies of DepR in regulating FK228 biosynthesis in Chromobacterium violaceum no. 968.
Q36819315New perspectives: Insights into oxidative stress from bacterial studies
Q92764979Oligoribonuclease Contributes to Tolerance to Aminoglycoside and β-Lactam Antibiotics by Regulating KatA in Pseudomonas aeruginosa
Q57294459OxyR regulates the transcriptional response to hydrogen peroxide
Q92672949OxyR senses sulfane sulfur and activates the genes for its removal in Escherichia coli
Q36185947OxyR-regulated catalase CatB promotes the virulence in rice via detoxifying hydrogen peroxide in Xanthomonas oryzae pv. oryzae
Q42030587OxyR2 Functions as a Three-state Redox Switch to Tightly Regulate Production of Prx2, a Peroxiredoxin of Vibrio vulnificus.
Q37223553Protocols for Molecular Modeling with Rosetta3 and RosettaScripts
Q37503911Pseudomonas aeruginosa Enolase Influences Bacterial Tolerance to Oxidative Stresses and Virulence
Q52597647PutA Is Required for Virulence and Regulated by PruR in Pseudomonas aeruginosa.
Q58790706Reduce, Induce, Thrive: Bacterial Redox Sensing during Pathogenesis
Q55499758RitR is an archetype for a novel family of redox sensors in the streptococci that has evolved from two-component response regulators and is required for pneumococcal colonization.
Q39682183Structural basis for DNA recognition by the transcription regulator MetR.
Q64235123Structural basis for HOCl recognition and regulation mechanisms of HypT, a hypochlorite-specific transcriptional regulator
Q47129169Structural basis of effector and operator recognition by the phenolic acid-responsive transcriptional regulator PadR.
Q59199785Structural snapshots of OxyR reveal the peroxidatic mechanism of H2O2 sensing
Q28552750The Role of Reactive Oxygen Species in Antibiotic-Induced Cell Death in Burkholderia cepacia Complex Bacteria
Q46408244The hydrogen peroxide hypersensitivity of OxyR2 in Vibrio vulnificus depends on conformational constraints.
Q40947197The solution configurations of inactive and activated DntR have implications for the sliding dimer mechanism of LysR transcription factors
Q36199932Transcription Factors That Defend Bacteria Against Reactive Oxygen Species
Q91623270Transcription of cis Antisense Small RNA MtlS in Vibrio cholerae Is Regulated by Transcription of Its Target Gene, mtlA