| review article | Q7318358 |
| scholarly article | Q13442814 |
| P50 | author | Larry Sklar | Q59753606 |
| P2093 | author name string | Bruce S Edwards | |
| P2860 | cites work | Phenotypic screening with human iPS cell-derived cardiomyocytes: HTS-compatible assays for interrogating cardiac hypertrophy | Q43769949 |
| Mixing small volumes for continuous high-throughput flow cytometry: performance of a mixing Y and peristaltic sample delivery | Q43916521 | ||
| The contribution of mechanistic understanding to phenotypic screening for first-in-class medicines | Q44143302 | ||
| High‐throughput flow cytometry: Validation in microvolume bioassays | Q44407454 | ||
| Intracellular phospho-protein staining techniques for flow cytometry: monitoring single cell signaling events | Q44593406 | ||
| An investigation of liquid carryover and sample residual for a high-throughput flow cytometer sample delivery system | Q44959658 | ||
| Resolution of dimly fluorescent particles: a practical measure of fluorescence sensitivity. | Q46023209 | ||
| High-content analysis to leverage a robust phenotypic profiling approach to vascular modulation | Q46568868 | ||
| Integration of virtual screening with high-throughput flow cytometry to identify novel small molecule formylpeptide receptor antagonists | Q46666020 | ||
| Pharmacologic characterization of a kinetic in vitro human co-culture angiogenesis model using clinically relevant compounds | Q46676600 | ||
| Analytical performance of an ultrasonic particle focusing flow cytometer | Q46959646 | ||
| The discovery of first-in-class drugs: origins and evolution. | Q48070614 | ||
| Time interval gating for analysis of cell function using flow cytometry | Q48649950 | ||
| Distinguishing modes of cell death using the ImageStream multispectral imaging flow cytometer. | Q49301662 | ||
| Development of phenotypic screening assays for γ-globin induction using primary human bone marrow day 7 erythroid progenitor cells. | Q50484219 | ||
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Q50734050 | ||
| Individualized systems medicine strategy to tailor treatments for patients with chemorefractory acute myeloid leukemia. | Q51781980 | ||
| Unravelling cancer stem cell potential. | Q53089167 | ||
| Plug flow cytometry: An automated coupling device for rapid sequential flow cytometric sample analysis. | Q53925209 | ||
| Multiplexing high-content flow (HCF) and quantitative high-throughput screening (qHTS) to identify compounds capable of decreasing cell viability, activating caspase 3/7, expressing annexin V, and changing mitochondrial membrane integrity. | Q54372681 | ||
| Biomolecular screening of formylpeptide receptor ligands with a sensitive, quantitative, high-throughput flow cytometry platform | Q57016985 | ||
| Performance of in-line microfluidic mixers in laminar flow for high-throughput flow cytometry | Q61772060 | ||
| Analysis of ligand-receptor interactions with the fluorescence activated cell sorter | Q67244663 | ||
| High throughput flow cytometry | Q73774939 | ||
| Drug development: Raise standards for preclinical cancer research | Q22348097 | ||
| Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum | Q24594356 | ||
| Isolation of rare circulating tumour cells in cancer patients by microchip technology | Q24597164 | ||
| mTOR: from growth signal integration to cancer, diabetes and ageing | Q24633662 | ||
| International Union of Basic and Clinical Pharmacology. LXXIII. Nomenclature for the formyl peptide receptor (FPR) family | Q24652940 | ||
| A deep profiler's guide to cytometry | Q26824238 | ||
| Mass cytometry: a highly multiplexed single-cell technology for advancing drug development | Q26853371 | ||
| Single cell analysis using surface enhanced Raman scattering (SERS) tags | Q26860552 | ||
| iPSCs and small molecules: a reciprocal effort towards better approaches for drug discovery | Q26865055 | ||
| Global analysis of protein localization in budding yeast | Q27653962 | ||
| Flow cytometry for high-throughput, high-content screening | Q28275173 | ||
| How to improve R&D productivity: the pharmaceutical industry's grand challenge | Q28314992 | ||
| A novel flow cytometric high throughput assay for a systematic study on molecular mechanisms underlying T cell receptor-mediated integrin activation | Q28475665 | ||
| Selective chemical inhibition of agr quorum sensing in Staphylococcus aureus promotes host defense with minimal impact on resistance | Q28539668 | ||
| Believe it or not: how much can we rely on published data on potential drug targets? | Q29547529 | ||
| How were new medicines discovered? | Q29616641 | ||
| Cell growth control: little eukaryotes make big contributions. | Q30357437 | ||
| The intersection of flow cytometry with microfluidics and microfabrication | Q30416353 | ||
| Identification of Inhibitors of triacylglyceride accumulation in muscle cells: comparing HTS results from 1536-well plate-based and high-content platforms | Q30421866 | ||
| Flow cytometry: retrospective, fundamentals and recent instrumentation. | Q30457706 | ||
| Multinode acoustic focusing for parallel flow cytometry. | Q30458031 | ||
| Multitarget magnetic activated cell sorter | Q30484761 | ||
| A parallel microfluidic flow cytometer for high-content screening | Q30499961 | ||
| High-throughput single-microparticle imaging flow analyzer | Q30523388 | ||
| Cytometry by time-of-flight shows combinatorial cytokine expression and virus-specific cell niches within a continuum of CD8+ T cell phenotypes | Q30543634 | ||
| A high-content screen identifies novel compounds that inhibit stress-induced TDP-43 cellular aggregation and associated cytotoxicity. | Q30570770 | ||
| Mixture-based synthetic combinatorial libraries. | Q30784532 | ||
| High-throughput microfluidic mixing and multiparametric cell sorting for bioactive compound screening | Q30828809 | ||
| HTPS flow cytometry: a novel platform for automated high throughput drug discovery and characterization | Q31028084 | ||
| Plug flow cytometry extends analytical capabilities in cell adhesion and receptor pharmacology | Q31912825 | ||
| High-throughput screening with HyperCyt flow cytometry to detect small molecule formylpeptide receptor ligands | Q33217398 | ||
| Fluorescent cell barcoding in flow cytometry allows high-throughput drug screening and signaling profiling | Q33240546 | ||
| Strategies for the use of mixture-based synthetic combinatorial libraries: scaffold ranking, direct testing in vivo, and enhanced deconvolution by computational methods | Q33309321 | ||
| Fluorogen-activating single-chain antibodies for imaging cell surface proteins | Q33312211 | ||
| High-content single-cell drug screening with phosphospecific flow cytometry | Q33312213 | ||
| High-throughput flow cytometry to detect selective inhibitors of ABCB1, ABCC1, and ABCG2 transporters | Q33315445 | ||
| Duplex high-throughput flow cytometry screen identifies two novel formylpeptide receptor family probes | Q33368728 | ||
| Serial time-encoded amplified imaging for real-time observation of fast dynamic phenomena | Q33437641 | ||
| Detection of intracellular granularity induction in prostate cancer cell lines by small molecules using the HyperCyt high-throughput flow cytometry system | Q33453105 | ||
| Polyplexed flow cytometry protein interaction assay: a novel high-throughput screening paradigm for RGS protein inhibitors | Q33468786 | ||
| Small-molecule screening using a human primary cell model of HIV latency identifies compounds that reverse latency without cellular activation | Q33508788 | ||
| An innovation in flow cytometry data collection and analysis producing a correlated multiple sample analysis in a single file. | Q33517552 | ||
| Identification of a small GTPase inhibitor using a high-throughput flow cytometry bead-based multiplex assay | Q33518293 | ||
| Use of flow cytometric methods to quantify protein-protein interactions. | Q33767917 | ||
| High-throughput screen for the chemical inhibitors of antiapoptotic bcl-2 family proteins by multiplex flow cytometry | Q33895708 | ||
| Fluorogen-activating proteins as biosensors of cell-surface proteins in living cells | Q34155877 | ||
| Induced pluripotent stem cells--opportunities for disease modelling and drug discovery | Q34231818 | ||
| Evolution of the cancer stem cell model | Q34408981 | ||
| Phenotypic screening in cancer drug discovery - past, present and future | Q34429484 | ||
| Flow cytometry enables a high-throughput homogeneous fluorescent antibody-binding assay for cytotoxic T cell lytic granule exocytosis | Q34480436 | ||
| Flow cytometric analysis of ligand-receptor interactions and molecular assemblies | Q34623561 | ||
| Encoding microcarriers: present and future technologies. | Q34742148 | ||
| Selective agonists and antagonists of formylpeptide receptors: duplex flow cytometry and mixture-based positional scanning libraries | Q34780074 | ||
| An HTS-compatible 3D colony formation assay to identify tumor-specific chemotherapeutics | Q34897995 | ||
| A chromatic explosion: the development and future of multiparameter flow cytometry. | Q34919897 | ||
| A high-throughput assay to identify modifiers of premature chromosome condensation | Q34975412 | ||
| HIV cell fusion assay: phenotypic screening tool for the identification of HIV entry inhibitors via CXCR4. | Q34976806 | ||
| Detection of phospholipidosis induction: a cell-based assay in high-throughput and high-content format. | Q34977885 | ||
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors | Q34987358 | ||
| Comparison of methods for image-based profiling of cellular morphological responses to small-molecule treatment | Q34991555 | ||
| Mass cytometry: technique for real time single cell multitarget immunoassay based on inductively coupled plasma time-of-flight mass spectrometry | Q34992218 | ||
| FRET-based calcium imaging: a tool for high-throughput/content phenotypic drug screening in Alzheimer disease | Q35039801 | ||
| Fluorescent genetic barcoding in mammalian cells for enhanced multiplexing capabilities in flow cytometry | Q35139322 | ||
| High-throughput secondary screening at the single-cell level | Q35235361 | ||
| A high-throughput phenotypic screen of cytotoxic T lymphocyte lytic granule exocytosis reveals candidate immunosuppressants | Q35404981 | ||
| The use of 3-D cultures for high-throughput screening: the multicellular spheroid model | Q35801815 | ||
| Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening | Q35803029 | ||
| Identification of a small molecule yeast TORC1 inhibitor with a multiplex screen based on flow cytometry | Q35903219 | ||
| The TOR signalling network from yeast to man. | Q36463859 | ||
| Characterization of a Cdc42 protein inhibitor and its use as a molecular probe | Q36708621 | ||
| Chip integrated strategies for acoustic separation and manipulation of cells and particles | Q36746386 | ||
| A phenotypic compound screening assay for lysosomal storage diseases | Q36759030 | ||
| Development of high-content assays for kidney progenitor cell expansion in transgenic zebrafish | Q37315733 | ||
| Cancer stem cells in solid tumors: an overview | Q37403282 | ||
| Multi-parameter phenotypic profiling: using cellular effects to characterize small-molecule compounds | Q37536897 | ||
| Genetic and environmental determinants of human NK cell diversity revealed by mass cytometry | Q37569278 | ||
| Engineering tumors: a tissue engineering perspective in cancer biology | Q37679204 | ||
| Cancer stem cells as the relevant biomass for drug discovery | Q37772680 | ||
| Primary cells and stem cells in drug discovery: emerging tools for high-throughput screening | Q37824151 | ||
| Phaedra, a protocol-driven system for analysis and validation of high-content imaging and flow cytometry | Q37974727 | ||
| Drug discovery in pharmaceutical industry: productivity challenges and trends | Q38012954 | ||
| Neoclassic drug discovery: the case for lead generation using phenotypic and functional approaches | Q38147719 | ||
| Evolution of biologics screening technologies | Q38166225 | ||
| Biology, detection, and clinical implications of circulating tumor cells | Q38268371 | ||
| Fluorescence-intensity multiplexing: simultaneous seven-marker, two-color immunophenotyping using flow cytometry | Q38419971 | ||
| Benchmarking of multivariate similarity measures for high-content screening fingerprints in phenotypic drug discovery | Q39094539 | ||
| High-content screening of natural products reveals novel nuclear export inhibitors | Q39094551 | ||
| Cell-based fuzzy metrics enhance high-content screening (HCS) assay robustness | Q39094555 | ||
| Highly multiplexed phenotypic imaging for cell proliferation studies | Q39118540 | ||
| Selected drugs with reported secondary cell-differentiating capacity prime latent HIV-1 infection for reactivation | Q39331564 | ||
| A high-throughput hybridoma selection method using fluorometric microvolume assay technology | Q40007437 | ||
| Sensitivity measurement and compensation in spectral imaging | Q40232681 | ||
| Simultaneous in vitro molecular screening of protein-peptide interactions by flow cytometry, using six Bcl-2 family proteins as examples. | Q40473386 | ||
| High-throughput flow cytometry bead-based multiplex assay for identification of Rho GTPase inhibitors | Q41972062 | ||
| Cluster cytometry for high-capacity bioanalysis. | Q42536029 | ||
| P433 | issue | 6 | |
| P921 | main subject | flow cytometry | Q1141429 |
| drug discovery | Q1418791 | ||
| P304 | page(s) | 689-707 | |
| P577 | publication date | 2015-03-24 | |
| P1433 | published in | Journal of Biomolecular Screening | Q6294856 |
| P1476 | title | Flow Cytometry: Impact on Early Drug Discovery | |
| P478 | volume | 20 |
| Q88907819 | A Fully Automated High-Throughput Flow Cytometry Screening System Enabling Phenotypic Drug Discovery |
| Q89351018 | Biologically Relevant Heterogeneity: Metrics and Practical Insights |
| Q28084264 | Cell-Based Assay Design for High-Content Screening of Drug Candidates |
| Q38805671 | Ferroptosis and Cell Death Analysis by Flow Cytometry |
| Q50428971 | Flow Cytometry Enables Multiplexed Measurements of Genetically Encoded Intramolecular FRET Sensors Suitable for Screening. |
| Q61758701 | High-Throughput Flow Cytometry Drug Combination Discovery with Novel Synergy Analysis Software, SynScreen |
| Q64389735 | High-Throughput Screening Approach for Identifying Compounds That Inhibit Nonhomologous End Joining |
| Q48531718 | Impact of a five-dimensional framework on R&D productivity at AstraZeneca. |
| Q90179514 | Label-Free Assay of Protein Tyrosine Phosphatase Activity in Single Cells |
| Q47776059 | Line-Focused Optical Excitation of Parallel Acoustic Focused Sample Streams for High Volumetric and Analytical Rate Flow Cytometry |
| Q30101118 | Multiplexed lipid bilayers on silica microspheres for analytical screening applications. |
| Q30788606 | Quantitative Magnetic Separation of Particles and Cells Using Gradient Magnetic Ratcheting |
| Q31049930 | Recent advances in quantitative high throughput and high content data analysis |
| Q64082848 | Sizing biological cells using a microfluidic acoustic flow cytometer |
| Q38837348 | Targeting efflux pumps to overcome antifungal drug resistance |
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