review article | Q7318358 |
scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1033538366 |
P356 | DOI | 10.1007/S12265-009-9129-2 |
P932 | PMC publication ID | 4342148 |
P698 | PubMed publication ID | 20560001 |
P5875 | ResearchGate publication ID | 44684660 |
P2093 | author name string | James A Spudich | |
Euan Ashley | |||
Leslie Leinwand | |||
Sivaraj Sivaramakrishnan | |||
P2860 | cites work | Myosin-V is a processive actin-based motor | Q22003739 |
Skeletal muscle expression and abnormal function of beta-myosin in hypertrophic cardiomyopathy | Q24309554 | ||
Myosin VI is a processive motor with a large step size | Q24555089 | ||
Molecular cloning and characterization of human cardiac alpha- and beta-form myosin heavy chain complementary DNA clones. Regulation of expression during development and pressure overload in human atrium | Q24629385 | ||
Single-molecule mechanics of R403Q cardiac myosin isolated from the mouse model of familial hypertrophic cardiomyopathy | Q28141697 | ||
Myosin-IXb is a single-headed and processive motor | Q28215994 | ||
The mechanism of muscular contraction | Q28237595 | ||
Differential cross-bridge kinetics of FHC myosin mutations R403Q and R453C in heterozygous mouse myocardium | Q28507314 | ||
Cardiac myosin missense mutations cause dilated cardiomyopathy in mouse models and depress molecular motor function. | Q28594348 | ||
The power stroke of myosin VI and the basis of reverse directionality | Q30478493 | ||
R403Q and L908V mutant beta-cardiac myosin from patients with familial hypertrophic cardiomyopathy exhibit enhanced mechanical performance at the single molecule level | Q30656473 | ||
Kinetic differences at the single molecule level account for the functional diversity of rabbit cardiac myosin isoforms | Q30756973 | ||
Single molecule high-resolution colocalization of Cy3 and Cy5 attached to macromolecules measures intramolecular distances through time | Q30854446 | ||
Functional consequences of mutations in the smooth muscle myosin heavy chain at sites implicated in familial hypertrophic cardiomyopathy | Q30884033 | ||
Building and using optical traps to study properties of molecular motors | Q31134487 | ||
Hypertrophic cardiomyopathy: etiology, diagnosis, and treatment | Q33156364 | ||
ELECTRON MICROSCOPE STUDIES ON THE STRUCTURE OF NATURAL AND SYNTHETIC PROTEIN FILAMENTS FROM STRIATED MUSCLE. | Q33191423 | ||
Hypertrophic and dilated cardiomyopathy mutations differentially affect the molecular force generation of mouse alpha-cardiac myosin in the laser trap assay | Q33277814 | ||
The myosin step size: measurement of the unit displacement per ATP hydrolyzed in an in vitro assay | Q33793860 | ||
Control of cardiac myosin heavy chain gene expression | Q34040340 | ||
Prevalence of hypertrophic cardiomyopathy in a general population of young adults. Echocardiographic analysis of 4111 subjects in the CARDIA Study. Coronary Artery Risk Development in (Young) Adults | Q34058337 | ||
Kinetic and equilibrium analysis of the myosin ATPase | Q34066040 | ||
Hypertrophic cardiomyopathy: a systematic review | Q34117625 | ||
Force measurements by micromanipulation of a single actin filament by glass needles | Q34177181 | ||
Sliding distance of actin filament induced by a myosin crossbridge during one ATP hydrolysis cycle. | Q34199192 | ||
Movement of myosin-coated fluorescent beads on actin cables in vitro | Q34266105 | ||
Single myosin molecule mechanics: piconewton forces and nanometre steps | Q34338098 | ||
Dilated cardiomyopathy: a genetically heterogeneous disease | Q34871768 | ||
Why choose myofibrils to study muscle myosin ATPase? | Q35580317 | ||
Molecular genetics and genomics of heart failure | Q35936390 | ||
Kinetic Analysis of Myosin and Actomyosin ATPase | Q36072483 | ||
Myosin-X: a molecular motor at the cell's fingertips | Q36248392 | ||
Walking with myosin V. | Q36354001 | ||
Sarcomere length-resting tension relation in single frog atrial cardiac cells | Q36528735 | ||
The kinetic mechanism of myosin V. | Q36700327 | ||
Protein kinase A does not alter economy of force maintenance in skinned rat cardiac trabeculae. | Q36701635 | ||
Expression of a mutation causing hypertrophic cardiomyopathy disrupts sarcomere assembly in adult feline cardiac myocytes | Q36708559 | ||
Functional effects of the hypertrophic cardiomyopathy R403Q mutation are different in an alpha- or beta-myosin heavy chain backbone | Q36761852 | ||
Sarcomere dynamics during muscular contraction and their implications to muscle function. | Q36832339 | ||
Myosin V from head to tail | Q37073565 | ||
Modulation of cardiac performance by motor protein gene transfer | Q37122799 | ||
Responses of single-ventricular myocytes to dynamic axial stretching | Q37159932 | ||
Fluorescent actin filaments move on myosin fixed to a glass surface | Q37396490 | ||
Direct observation of the mechanochemical coupling in myosin Va during processive movement | Q37416808 | ||
A new method of attachment of isolated mammalian ventricular myocytes for tension recording: length dependence of passive and active tension | Q41192393 | ||
Heterologous expression of a cardiomyopathic myosin that is defective in its actin interaction | Q41493794 | ||
Actomyosin interaction in striated muscle | Q41543090 | ||
A novel form of motility in filopodia revealed by imaging myosin-X at the single-molecule level | Q41978648 | ||
Motor function and regulation of myosin X. | Q43678692 | ||
Loaded shortening and power output in cardiac myocytes are dependent on myosin heavy chain isoform expression | Q43713902 | ||
The mechanism of myosin VI translocation and its load-induced anchoring | Q44790017 | ||
Human homozygous R403W mutant cardiac myosin presents disproportionate enhancement of mechanical and enzymatic properties. | Q44792718 | ||
Myosin VI walks hand-over-hand along actin | Q45001874 | ||
Cardiac transgenic and gene transfer strategies converge to support an important role for troponin I in regulating relaxation in cardiac myocytes. | Q45060973 | ||
Contractile dysfunction of cardiomyopathic hamster myocytes is pronounced under high load conditions | Q46502206 | ||
Dynamics of the unbound head during myosin V processive translocation | Q46692109 | ||
Low thyroid function leads to cardiac atrophy with chamber dilatation, impaired myocardial blood flow, loss of arterioles, and severe systolic dysfunction | Q46795007 | ||
Myosin step size. Estimation from slow sliding movement of actin over low densities of heavy meromyosin | Q47443144 | ||
Expression of green fluorescent protein impairs the force-generating ability of isolated rat ventricular cardiomyocytes. | Q50736830 | ||
Fluorescence imaging with one nanometer accuracy: application to molecular motors. | Q50761313 | ||
Calcium-independent negative inotropy by beta-myosin heavy chain gene transfer in cardiac myocytes. | Q51046536 | ||
Microtubules modulate the stiffness of cardiomyocytes against shear stress. | Q51812166 | ||
Force-length relations in isolated intact cardiomyocytes subjected to dynamic changes in mechanical load. | Q53584942 | ||
Contractile force measured in unskinned isolated adult rat heart fibres | Q54563996 | ||
In vitro motilities of the unconventional myosins, brush border myosin-I, and chick brain myosin-V exhibit assay-dependent differences in velocity | Q58134478 | ||
p38-MAPK Induced Dephosphorylation of α-Tropomyosin Is Associated With Depression of Myocardial Sarcomeric Tension and ATPase Activity | Q58198510 | ||
Motor molecules in motion | Q59013657 | ||
Movement of myosin-coated beads on oriented filaments reconstituted from purified actin | Q59061286 | ||
Mutations in the motor domain modulate myosin activity and myofibril organization | Q64377437 | ||
Sliding velocity of isolated rabbit cardiac myosin correlates with isozyme distribution | Q67546911 | ||
Evidence of genetic heterogeneity in five kindreds with familial hypertrophic cardiomyopathy | Q67742146 | ||
Relation of properties of isolated myosin to those of intact muscles of the cat and sloth | Q68406038 | ||
Biochemical and structural studies of actomyosin-like proteins from non-muscle cells. II. Purification, properties, and membrane association of actin from amoebae of Dictyostelium discoideum | Q68534864 | ||
Control of myosin heavy chain expression in cardiac hypertrophy | Q70023080 | ||
Cardiac myosin heavy chain mRNA expression and myocardial function in the mouse heart | Q70162261 | ||
Brain myosin-V is a two-headed unconventional myosin with motor activity | Q70488210 | ||
Comparison of the myosin and actomyosin ATPase mechanisms of the four types of vertebrate muscles | Q70531440 | ||
Depressed sliding velocity of isolated cardiac myosin from cardiomyopathic hamsters: evidence for an alteration in mechanical interaction of actomyosin | Q70617424 | ||
Cardiac V1 and V3 myosins differ in their hydrolytic and mechanical activities in vitro | Q71888375 | ||
Single-molecule analysis of the actomyosin motor using nano-manipulation | Q72310250 | ||
The in vitro motility activity of beta-cardiac myosin depends on the nature of the beta-myosin heavy chain gene mutation in hypertrophic cardiomyopathy | Q73388735 | ||
Membrane potential of rat ventricular myocytes responds to axial stretch in phase, amplitude and speed-dependent manners | Q79284696 | ||
Single cell mechanics of rat cardiomyocytes under isometric, unloaded, and physiologically loaded conditions | Q79735185 | ||
Carbon fiber technique for the investigation of single-cell mechanics in intact cardiac myocytes | Q80093199 | ||
Cardiac myosin isoforms from different species have unique enzymatic and mechanical properties | Q81035642 | ||
P433 | issue | 4 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 426-440 | |
P577 | publication date | 2009-09-29 | |
P1433 | published in | Journal of Cardiovascular Translational Research | Q6294906 |
P1476 | title | Insights into human beta-cardiac myosin function from single molecule and single cell studies | |
P478 | volume | 2 |
Q47210536 | Adaptation and validation of the ACMG/AMP variant classification framework for MYH7-associated inherited cardiomyopathies: recommendations by ClinGen's Inherited Cardiomyopathy Expert Panel |
Q36045425 | Cell-intrinsic functional effects of the α-cardiac myosin Arg-403-Gln mutation in familial hypertrophic cardiomyopathy |
Q26770578 | Effects of hypertrophic and dilated cardiomyopathy mutations on power output by human β-cardiac myosin |
Q35075551 | Effects of troponin T cardiomyopathy mutations on the calcium sensitivity of the regulated thin filament and the actomyosin cross-bridge kinetics of human β-cardiac myosin |
Q36083735 | Electrical and Mechanical Strategies to Enable Cardiac Repair and Regeneration. |
Q27320554 | Ensemble force changes that result from human cardiac myosin mutations and a small-molecule effector |
Q98881672 | Gaining insight into cellular cardiac physiology using single particle tracking |
Q37855688 | How do mutations in contractile proteins cause the primary familial cardiomyopathies? |
Q39440818 | Hypertrophic cardiomyopathy and the myosin mesa: viewing an old disease in a new light |
Q34772983 | Identifying sarcomere gene mutations in hypertrophic cardiomyopathy: a personal history |
Q39429314 | Immortalization of bone marrow-derived porcine mesenchymal stem cells and their differentiation into cells expressing cardiac phenotypic markers. |
Q38940777 | Insights from molecular dynamics simulations for computational protein design |
Q34549974 | Modulating Beta-Cardiac Myosin Function at the Molecular and Tissue Levels. |
Q91972985 | Myocardial Contractility: Historical and Contemporary Considerations |
Q36532652 | Sacrificial layer technique for axial force post assay of immature cardiomyocytes |
Q36823735 | Subtle abnormalities in contractile function are an early manifestation of sarcomere mutations in dilated cardiomyopathy |
Q64883689 | The Molecular Mechanisms of Mutations in Actin and Myosin that Cause Inherited Myopathy. |
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