Knockdown of hypothalamic RFRP3 prevents chronic stress-induced infertility and embryo resorption.

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Knockdown of hypothalamic RFRP3 prevents chronic stress-induced infertility and embryo resorption. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.7554/ELIFE.04316
P932PMC publication ID4289855
P698PubMed publication ID25581095

P50authorSandra E MuroyQ86513955
Lance KriegsfeldQ88292050
P2093author name stringGeorge E Bentley
Sheng Zhao
Daniela Kaufer
Anna C Geraghty
P2860cites workIdentification of human GnIH homologs, RFRP-1 and RFRP-3, and the cognate receptor, GPR147 in the human hypothalamic pituitary axisQ24293068
Stress and the suppression of subordinate reproduction in cooperatively breeding meerkatsQ29029180
Reproductive Suppression Among Female Mammals: Implications for Biomedicine and Sexual Selection TheoryQ29303956
Contextual and auditory fear conditioning are mediated by the lateral, basal, and central amygdaloid nuclei in ratsQ30500317
Clinical review 105: Stress and the reproductive cycleQ33662441
Effects of stress on reproduction in non-rodent mammals: the role of glucocorticoids and sex differencesQ33948979
The roles of RFamide-related peptide-3 in mammalian reproductive function and behaviourQ34015369
Characterization of the potent gonadotropin-releasing activity of RF9, a selective antagonist of RF-amide-related peptides and neuropeptide FF receptors: physiological and pharmacological implicationsQ34099107
Stress reduces conception probabilities across the fertile window: evidence in support of relaxationQ34284536
Identification and characterization of a gonadotropin-inhibitory system in the brains of mammalsQ34479271
Hypophysiotropic role of RFamide-related peptide-3 in the inhibition of LH secretion in female ratsQ34800399
Identification, expression, and physiological functions of Siberian hamster gonadotropin-inhibitory hormoneQ35646083
Rat RFamide-related peptide-3 stimulates GH secretion, inhibits LH secretion, and has variable effects on sex behavior in the adult male rat.Q35697346
Effect of Stress on the Activity of the Hypothalamic-Pituitary-Gonadal Axis: Peripheral and Central Mechanisms1Q36447886
Neuroendocrine regulation of feminine sexual behavior: lessons from rodent models and thoughts about humansQ36901990
Stress increases putative gonadotropin inhibitory hormone and decreases luteinizing hormone in male ratsQ37233701
Comprehensive algorithm for quantitative real-time polymerase chain reactionQ37276441
Restraint stress inhibits mouse implantation: temporal window and the involvement of HB-EGF, estrogen and progesteroneQ37308948
Optimizing natural fertilityQ37324894
Gonadotropin-inhibitory hormone reduces sexual motivation but not lordosis behavior in female Syrian hamsters (Mesocricetus auratus).Q37639992
Molecular basis for the activation of gonadotropin-inhibitory hormone gene transcription by corticosteroneQ39022543
Gonadotropin-inhibitory hormone inhibits GnRH-induced gonadotropin subunit gene transcriptions by inhibiting AC/cAMP/PKA-dependent ERK pathway in LβT2 cellsQ39388418
Effects of Chronic Immobilization Stress on Pituitary Hormone Secretion, on Hypothalamic Factor Levels, and on Pituitary Responsiveness to LHRH and TRH in Female RatsQ39695743
Cells expressing RFamide-related peptide-1/3, the mammalian gonadotropin-inhibitory hormone orthologs, are not hypophysiotropic neuroendocrine neurons in the rat.Q42444892
Gonadotropin inhibitory hormone inhibits basal forebrain vGluT2-gonadotropin-releasing hormone neurons via a direct postsynaptic mechanismQ42449100
Characterization of the inhibitory roles of RFRP3, the mammalian ortholog of GnIH, in the control of gonadotropin secretion in the rat: in vivo and in vitro studies.Q42470776
Gonadotropin-inhibitory hormone identification, cDNA cloning, and distribution in rhesus macaque brainQ43257784
Central and peripheral effects of RFamide-related peptide-3 on luteinizing hormone and prolactin secretion in ratsQ46235534
RFamide-related peptide-3 receptor gene expression in GnRH and kisspeptin neurons and GnRH-dependent mechanism of actionQ47631520
Effect of RF-amide-related peptide-3 on luteinizing hormone and follicle-stimulating hormone synthesis and secretion in ovine pituitary gonadotropes.Q48440313
A novel rat hypothalamic RFamide-related peptide identified by immunoaffinity chromatography and mass spectrometryQ48684705
Corticotropin-releasing factor is a potent inhibitor of sexual receptivity in the female rat.Q48738377
Distribution of novel RFamide-related peptide-like immunoreactivity in the mouse central nervous systemQ48968504
Effects of long-term psychological stress on sexual behavior and brain catecholamine levelsQ49092649
Gonadotrophin inhibitory hormone depresses gonadotrophin alpha and follicle-stimulating hormone beta subunit expression in the pituitary of the domestic chicken.Q49119428
RFamide-related peptide-3, a mammalian gonadotropin-inhibitory hormone ortholog, regulates gonadotropin-releasing hormone neuron firing in the mouse.Q50606894
Effects of mounts without intromission upon the behavior of female rats during the onset of estrogen-induced heatQ52328357
A Novel Avian Hypothalamic Peptide Inhibiting Gonadotropin ReleaseQ60961718
P407language of work or nameEnglishQ1860
P577publication date2015-01-12
P1433published ineLifeQ2000008
P1476titleKnockdown of hypothalamic RFRP3 prevents chronic stress-induced infertility and embryo resorption
P478volume4

Reverse relations

cites work (P2860)
Q38946836Aggressive interactions are associated with reductions in RFamide-related peptide, but not kisspeptin, neuronal activation in mice
Q91414301Brain mapping of the gonadotropin-inhibitory hormone-related peptide 2 with a novel antibody suggests a connection with emotional reactivity in the Japanese quail (Coturnix japonica, Temminck & Schlegel, 1849)
Q40754851Differential response of GnIH in the brain and gonads following acute stress in a songbird
Q39380126Food restriction-induced changes in motivation differ with stages of the estrous cycle and are closely linked to RFamide-related peptide-3 but not kisspeptin in Syrian hamsters.
Q64058575Functional Implications of RFRP-3 in the Central Control of Daily and Seasonal Rhythms in Reproduction
Q88292053Gonadotrophin-inhibitory hormone and its mammalian orthologue RFamide-related peptide-3: Discovery and functional implications for reproduction and stress
Q37737530Gonadotropin-Inhibitory Hormone Plays Roles in Stress-Induced Reproductive Dysfunction
Q30354349Maternal and Early-Life Circadian Disruption Have Long-Lasting Negative Consequences on Offspring Development and Adult Behavior in Mice.
Q90109157Neural and endocrine mechanisms underlying stress-induced suppression of pulsatile LH secretion
Q46450328Patterns of hypothalamic GnIH change over the reproductive period in starlings and rats
Q28067975Peripheral and Central Mechanisms Involved in the Hormonal Control of Male and Female Reproduction
Q31006872Putting the brakes on reproduction: Implications for conservation, global climate change and biomedicine
Q46113199RFamide-related Peptide-3 and the Trade-off between Reproductive and Ingestive Behavior
Q42323950RFamide-related peptide-3 (RFRP-3) suppresses sexual maturation in a eusocial mammal
Q47548408Sex-biased transcriptomic response of the reproductive axis to stress
Q50300992Social structure as a strategy to mitigate the costs of group living: a comparison of gelada and guereza monkeys
Q47167938Stress and the HPA Axis: Balancing Homeostasis and Fertility.
Q98188986Stressful life events, the incidence of infertility, and the moderating effect of maternal responsiveness: a longitudinal study
Q37022809The Role of RFamide-Related Peptide-3 in Age-Related Reproductive Decline in Female Rats
Q47824790The protective effect of the Vacha rhizome extract on chronic stress-induced immunodeficiency in rat.
Q60922678The roles of RFamide-related peptides (RFRPs), mammalian gonadotropin-inhibitory hormone (GnIH) orthologues in female reproduction
Q38883710What's in a Name? Roles of RFamide-Related Peptides Beyond Gonadotrophin Inhibition

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