Shiga toxin-producing Escherichia coli O104:H4: an emerging pathogen with enhanced virulence

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Shiga toxin-producing Escherichia coli O104:H4: an emerging pathogen with enhanced virulence is …
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scholarly articleQ13442814

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P356DOI10.1016/J.IDC.2013.05.002
P932PMC publication ID3800737
P698PubMed publication ID24011834

P2093author name stringJohn M Leong
Dakshina M Jandhyala
Beth A McCormick
Erik J Boll
Vijay Vanguri
Yushuan Lai
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Enteroaggregative Escherichia coli expresses a novel flagellin that causes IL-8 release from intestinal epithelial cells.Q30305779
Virulence of the Shiga toxin type 2-expressing Escherichia coli O104:H4 German outbreak isolate in two animal modelsQ30416578
The fimbriae of enteroaggregative Escherichia coli induce epithelial inflammation in vitro and in a human intestinal xenograft modelQ30417449
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CXCL1/KC and CXCL2/MIP-2 are critical effectors and potential targets for therapy of Escherichia coli O157:H7-associated renal inflammationQ30442733
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Correlation between in vivo biofilm formation and virulence gene expression in Escherichia coli O104:H4.Q34358725
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An IncI1 plasmid contributes to the adherence of the atypical enteroaggregative Escherichia coli strain C1096 to cultured cells and abiotic surfacesQ34492804
A novel dispersin protein in enteroaggregative Escherichia coliQ34815535
Aggregative adherence fimbria II, a second fimbrial antigen mediating aggregative adherence in enteroaggregative Escherichia coli.Q35556396
Presence of enterohemorrhagic Escherichia coli ST678/O104:H4 in France prior to 2011Q35599259
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Multicenter evaluation of a sequence-based protocol for subtyping Shiga toxins and standardizing Stx nomenclatureQ36172302
Enteroaggregative Escherichia coli heat-stable enterotoxin 1 represents another subfamily of E. coli heat-stable toxinQ36219150
New adhesin of enteroaggregative Escherichia coli related to the Afa/Dr/AAF familyQ36747051
Distinctive patterns of adherence of enteropathogenic Escherichia coli to HeLa cellsQ37077312
Verocytotoxin-producing Escherichia coli (VTEC).Q37467549
Acute bloody diarrhea: a medical emergency for patients of all ages.Q37490296
Autotransporters and virulence of enteroaggregative E. coli.Q37884346
Pathogenesis of Shiga-toxin producing escherichia coli.Q37931746
The induction of apoptosis by Shiga toxins and ricinQ37963278
Enteroaggregative Escherichia coli pathotype: a genetically heterogeneous emerging foodborne enteropathogenQ38024836
Potential role of adherence traits of Escherichia coli in persistent diarrhea in an urban Brazilian slumQ39243122
Cytoskeletal effects induced by pet, the serine protease enterotoxin of enteroaggregative Escherichia coliQ39610447
Enteroaggregative Escherichia coli Disrupts Epithelial Cell Tight JunctionsQ39658552
Adhesion of enteroaggregative Escherichia coli to pediatric intestinal mucosa in vitroQ39826618
AggR, a transcriptional activator of aggregative adherence fimbria I expression in enteroaggregative Escherichia coliQ39896258
Laboratory investigation of enteroaggregative Escherichia coli O untypeable:H10 associated with a massive outbreak of gastrointestinal illnessQ40014564
Studies with enteroaggregative Escherichia coli in the gnotobiotic piglet gastroenteritis modelQ40152628
Diarrheagenic Escherichia coli infection in Baltimore, Maryland, and New Haven, Connecticut.Q40474671
Commensal bacteria influence Escherichia coli O157:H7 persistence and Shiga toxin production in the mouse intestineQ42203695
Similarity of Shiga toxin-producing Escherichia coli O104:H4 strains from Italy and GermanyQ42572253
Proteomic and microarray characterization of the AggR regulon identifies a pheU pathogenicity island in enteroaggregative Escherichia coliQ42596037
The mode of action of Shiga toxin on peptide elongation of eukaryotic protein synthesisQ42856082
A randomized, double-blind, multicenter study of rifaximin compared with placebo and with ciprofloxacin in the treatment of travelers' diarrheaQ43894968
A tyrosine-phosphorylated 12-amino-acid sequence of enteropathogenic Escherichia coli Tir binds the host adaptor protein Nck and is required for Nck localization to actin pedestalsQ43936783
Enteroaggregative Escherichia coli diarrhea in travelers: response to rifaximin therapyQ44797478
Enteroaggregative Escherichia coli associated with a foodborne outbreak of gastroenteritisQ44883649
Clinical spectrum of Shiga toxin-producing Escherichia coli (STEC) in adults and childrenQ44939982
Analysis of collection of hemolytic uremic syndrome-associated enterohemorrhagic Escherichia coliQ33380625
Treatment and outcome of Shiga-toxin-associated hemolytic uremic syndrome (HUS).Q33380757
Shiga toxin-associated hemolytic uremic syndrome and thrombotic thrombocytopenic purpura: distinct mechanisms of pathogenesisQ33383009
Hemolytic uremic syndrome and death in persons with Escherichia coli O157:H7 infection, foodborne diseases active surveillance network sites, 2000-2006.Q33386636
Recommendations for diagnosis of shiga toxin--producing Escherichia coli infections by clinical laboratoriesQ33386665
Treatment of typical (enteropathic) hemolytic uremic syndromeQ33392003
Escherichia coli Shiga Toxin Mechanisms of Action in Renal DiseaseQ33394010
Epidemic profile of Shiga-toxin-producing Escherichia coli O104:H4 outbreak in GermanyQ33395886
Characterisation of the Escherichia coli strain associated with an outbreak of haemolytic uraemic syndrome in Germany, 2011: a microbiological studyQ33395933
Early volume expansion during diarrhea and relative nephroprotection during subsequent hemolytic uremic syndromeQ33396329
Hemolytic-uremic syndrome during an outbreak of Escherichia coli O157:H7 infections in institutions for mentally retarded persons: clinical and epidemiologic observationsQ33396501
Management of an acute outbreak of diarrhoea-associated haemolytic uraemic syndrome with early plasma exchange in adults from southern Denmark: an observational studyQ33396885
Treatment of severe neurological deficits with IgG depletion through immunoadsorption in patients with Escherichia coli O104:H4-associated haemolytic uraemic syndrome: a prospective trialQ33397004
Antibiotic treatment of Escherichia coli O157 infection and the risk of hemolytic uremic syndrome, MinnesotaQ33397014
German outbreak of Escherichia coli O104:H4 associated with sproutsQ33397821
Management of hemolytic uremic syndromeQ33399370
Association between azithromycin therapy and duration of bacterial shedding among patients with Shiga toxin-producing enteroaggregative Escherichia coli O104:H4.Q33400244
Validation of treatment strategies for enterohaemorrhagic Escherichia coli O104:H4 induced haemolytic uraemic syndrome: case-control studyQ33402456
Renal and neurological involvement in typical Shiga toxin-associated HUS.Q33403361
Best supportive care and therapeutic plasma exchange with or without eculizumab in Shiga-toxin-producing E. coli O104:H4 induced haemolytic-uraemic syndrome: an analysis of the German STEC-HUS registryQ33404151
Ciprofloxacin reduces the risk of hemolytic uremic syndrome in patients with Escherichia coli O104:H4-associated diarrhea.Q33405117
A severe outbreak of Escherichia coli O157:H7--associated hemorrhagic colitis in a nursing homeQ33450098
A continuing assessment of risk factors for the development of Escherichia coli O157:H7-associated hemolytic uremic syndrome.Q33491139
Endothelial heterogeneity in Shiga toxin receptors and responses.Q33493734
Predictors of hemolytic uremic syndrome in children during a large outbreak of Escherichia coli O157:H7 infectionsQ33499640
Strain-specific differences in the amount of Shiga toxin released from enterohemorrhagic Escherichia coli O157 following exposure to subinhibitory concentrations of antimicrobial agents.Q33505061
The immunogenic SigA enterotoxin of Shigella flexneri 2a binds to HEp-2 cells and induces fodrin redistribution in intoxicated epithelial cellsQ33518453
Effect of shigella enterotoxin 1 (ShET1) on rabbit intestine in vitro and in vivoQ33617990
Quinolone antibiotics induce Shiga toxin-encoding bacteriophages, toxin production, and death in mice.Q33889513
Shiga toxins induce, superinduce, and stabilize a variety of C-X-C chemokine mRNAs in intestinal epithelial cells, resulting in increased chemokine expressionQ34009265
Site of action of a Vero toxin (VT2) from Escherichia coli O157:H7 and of Shiga toxin on eukaryotic ribosomes. RNA N-glycosidase activity of the toxins.Q34049372
Different classes of antibiotics differentially influence shiga toxin productionQ34108726
Patterns of adherence of diarrheagenic Escherichia coli to HEp-2 cellsQ34173805
Pic, an autotransporter protein secreted by different pathogens in the Enterobacteriaceae family, is a potent mucus secretagogueQ34177330
P433issue3
P921main subjectEscherichia coliQ25419
emerging pathogenQ108429945
P304page(s)631-649
P577publication date2013-07-24
P1433published inInfectious Disease Clinics of North AmericaQ15754797
P1476titleShiga toxin-producing Escherichia coli O104:H4: an emerging pathogen with enhanced virulence
P478volume27

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Q30657658Shiga toxin type-2 (Stx2) induces glutamate release via phosphoinositide 3-kinase (PI3K) pathway in murine neurons
Q35154085Two novel EHEC/EAEC hybrid strains isolated from human infections.

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