Genomic organization, tissue distribution and functional characterization of the rat Pate gene cluster

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Genomic organization, tissue distribution and functional characterization of the rat Pate gene cluster is …
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scholarly articleQ13442814

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P819ADS bibcode2012PLoSO...732633R
P356DOI10.1371/JOURNAL.PONE.0032633
P932PMC publication ID3316536
P698PubMed publication ID22479333
P5875ResearchGate publication ID223960961

P2093author name stringSuresh Yenugu
Angireddy Rajesh
P2860cites workAntimicrobial responses in the male reproductive tract of lipopolysaccharide challenged ratsQ83099963
HE2beta and HE2gamma, new members of an epididymis-specific family of androgen-regulated proteins in the humanQ22253255
Primate epididymis-specific proteins: characterization of ESC42, a novel protein containing a trefoil-like motif in monkey and humanQ24291705
PATE gene clusters code for multiple, secreted TFP/Ly-6/uPAR proteins that are expressed in reproductive and neuron-rich tissues and possess neuromodulatory activityQ24316881
Antibacterial properties of the sperm-binding proteins and peptides of human epididymis 2 (HE2) family; salt sensitivity, structural dependence and their interaction with outer and cytoplasmic membranes of Escherichia coliQ24529975
LCN6, a novel human epididymal lipocalinQ24799292
NMR structure of bucandin, a neurotoxin from the venom of the Malayan krait (Bungarus candidus)Q27636643
Structure-function relationships in the interaction between the urokinase-type plasminogen activator and its receptorQ28188116
Cystatin 11: a new member of the cystatin type 2 familyQ28205478
Molecular evolution and phylogeny of elapid snake venom three-finger toxinsQ28205651
SLLP1, a unique, intra-acrosomal, non-bacteriolytic, c lysozyme-like protein of human spermatozoaQ28212246
Molecular cloning and characterization of three novel lysozyme-like genes, predominantly expressed in the male reproductive system of humans, belonging to the c-type lysozyme/alpha-lactalbumin familyQ28261425
The androgen-regulated epididymal sperm-binding protein, human beta-defensin 118 (DEFB118) (formerly ESC42), is an antimicrobial beta-defensin.Q29871486
Testicular regulation of epididymal gene expression.Q30304625
Mouse cysteine-rich secretory protein 4 (CRISP4): a member of the Crisp family exclusively expressed in the epididymis in an androgen-dependent mannerQ33211237
Bactericidal activity of mammalian cathelicidin-derived peptides.Q34004332
PATE, a gene expressed in prostate cancer, normal prostate, and testis, identified by a functional genomic approachQ34016309
Regulation of gene transcription in the epididymisQ34292987
Antimicrobial activity of human EPPIN, an androgen-regulated, sperm-bound protein with a whey acidic protein motifQ34330422
Identification, cloning and functional characterization of novel beta-defensins in the rat (Rattus norvegicus).Q34496775
Host defense proteins of the male reproductive tract.Q34788151
Contribution of epididymal secretory proteins for spermatozoa maturationQ35097494
Members of the murine Pate family are predominantly expressed in the epididymis in a segment-specific fashion and regulated by androgens and other testicular factorsQ35339268
Biosynthesis and molecular cloning of sulfated glycoprotein 2 secreted by rat Sertoli cellsQ36470996
Antibacterial activity of antileukoprotease.Q39826482
The PATE gene is expressed in the accessory tissues of the human male genital tract and encodes a secreted sperm-associated proteinQ40441337
An epididymis-specific beta-defensin is important for the initiation of sperm maturationQ40560329
Structure-function relationships in the receptor for urokinase-type plasminogen activator. Comparison to other members of the Ly-6 family and snake venom alpha-neurotoxinsQ40683497
Specialized gene expression in the epididymis.Q40954700
Comparison, characterization, and identification of proteases and protease inhibitors in epididymal fluids of domestic mammals. Matrix metalloproteinases are major fluid gelatinases.Q43967607
Novel families of toxin-like peptides in insects and mammals: a computational approach.Q45965405
Identification and characterization of Wfdc gene expression in the male reproductive tract of the rat.Q46217516
Effects of seminal vesicle fluid components on sperm motility in the house mouseQ46241008
Activation of toll-like receptor 4 (TLR4) by in vivo and in vitro exposure of rat epididymis to lipopolysaccharide from Escherichia Coli.Q46429349
Concentration of testosterone in testis fluid of the rat.Q47843833
Developmental expression of an androgen-regulated epididymal protein.Q52245459
Purification, structure, and characterization of caltrin proteins from seminal vesicle of the rat and mouseQ67907295
Effects of seminal vesicle removal on fertility and uterine sperm motility in the house mouseQ69685548
Purification and characterization of a sulfated glycoprotein secreted by Sertoli cellsQ69715215
Androgen levels in the rete testis fluid during sexual developmentQ70793779
Purification and characterization of the active precursor of a human sperm motility inhibitor secreted by the seminal vesicles: identity with semenogelinQ71702479
Metabolism of Progesterone by Rat Testicular Homogenates. II. Changes with AgeQ72843418
Cystatin and cystatin-derived peptides have antibacterial activity against the pathogen Porphyromonas gingivalisQ77726065
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)e32633
P577publication date2012-03-30
P1433published inPLOS OneQ564954
P1476titleGenomic organization, tissue distribution and functional characterization of the rat Pate gene cluster
P478volume7

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cites work (P2860)
Q35810626IL-22/STAT3-Induced Increases in SLURP1 Expression within Psoriatic Lesions Exerts Antimicrobial Effects against Staphylococcus aureus.
Q35675081Identification and expression of an uncharacterized Ly-6 gene cluster in zebrafish Danio rerio
Q27324489In Silico and Biochemical Characterization of Lysozyme-Like Proteins in the Rat
Q35698858Mechanism of antibacterial action of the alcoholic extracts of Hemidesmus indicus (L.) R. Br. ex Schult, Leucas aspera (Wild.), Plumbago zeylanica L., and Tridax procumbens (L.) R. Br. ex Schult
Q34788262Sperm-associated antigen 11A is expressed exclusively in the principal cells of the mouse caput epididymis in an androgen-dependent manner.
Q92632929Uroplakin expression in the male reproductive tract of rat
Q50882969shRNA mediated ablation of prostate and testis expressed (Pate) messenger RNA results in impaired sperm function and fertility.

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