Intervertebral disc degeneration and ectopic bone formation in apolipoprotein E knockout mice

scientific article

Intervertebral disc degeneration and ectopic bone formation in apolipoprotein E knockout mice is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/JOR.22216
P932PMC publication ID3535577
P698PubMed publication ID22915292

P2093author name stringLi Jin
Dawei Zhang
Xudong Li
Adam L Shimer
Francis H Shen
Davis L Reames
P2860cites workThe role of interleukin-1 in the pathogenesis of human intervertebral disc degenerationQ24817050
Demineralized bone matrix gelatin as scaffold for osteochondral tissue engineeringQ30438937
Mouse growth and differentiation factor-5 protein and DNA therapy potentiates intervertebral disc cell aggregation and chondrogenic gene expressionQ30444872
Nucleus pulposus explant culture modelQ30447390
Effects of gender and age on the association of apolipoprotein E epsilon4 with bone mineral density, bone turnover and the risk of fractures in older peopleQ30743347
ApoE gene deficiency enhances the reduction of bone formation induced by a high-fat diet through the stimulation of p53-mediated apoptosis in osteoblastic cellsQ33280147
Fas/FasL interaction of nucleus pulposus and cancer cells with the activation of caspasesQ33969742
Proinflammatory cytokine expression profile in degenerated and herniated human intervertebral disc tissuesQ34050359
Interleukin‐17 synergizes with IFNγ or TNFα to promote inflammatory mediator release and intercellular adhesion molecule‐1 (ICAM‐1) expression in human intervertebral disc cellsQ34430562
The pathophysiology of the intervertebral discQ34504785
Cardiovascular and lifestyle risk factors in lumbar radicular pain or clinically defined sciatica: a systematic reviewQ36274822
Molecular pathogenic factors in symptomatic disc degenerationQ36314164
2002 SSE Award Competition in Basic Science: expression of major matrix metalloproteinases is associated with intervertebral disc degradation and resorptionQ36723561
Matrix synthesis and degradation in human intervertebral disc degeneration.Q36883824
Risk factors of atherosclerosis and shoulder pain--is there an association? A systematic reviewQ36950658
Atherosclerosis and disc degeneration/low-back pain--a systematic reviewQ37425578
The role of apolipoprotein E in bone metabolismQ37907478
Nutrition of the intervertebral disc: solute transport and metabolismQ39345516
Atherosclerotic calcification: relation to developmental osteogenesisQ40598040
Activation of inducible nitric oxide synthase increases MMP-2 and MMP-9 levels in ApoE-knockout mice.Q42750815
Apolipoprotein E-dependent inverse regulation of vertebral bone and adipose tissue mass in C57Bl/6 mice: modulation by diet-induced obesityQ42969279
Greater loss of axons in primary progressive multiple sclerosis plaques compared to secondary progressive disease.Q43645390
Increased bone formation in mice lacking apolipoprotein E.Q45222081
Mineral surface in calcified plaque is like that of bone: further evidence for regulated mineralizationQ46276752
Chronic kidney disease bone and mineral disorder (CKD-MBD) in apolipoprotein E-deficient mice with chronic renal failure.Q46296691
Osteogenesis associates with inflammation in early-stage atherosclerosis evaluated by molecular imaging in vivoQ46881126
Factors associated with lumbar intervertebral disc degeneration in the elderlyQ46883080
Chronic hypoxia accelerates the progression of atherosclerosis in apolipoprotein E-knockout miceQ46938472
Apolipoprotein E gene mapping and expression: localization of the structural gene to human chromosome 19 and expression of ApoE mRNA in lipoprotein- and non-lipoprotein-producing tissuesQ48470999
Effect of intervertebral disc degeneration on disc cell viability: a numerical investigation.Q51526042
Cardiovascular risk factors for physician-diagnosed lumbar disc herniation.Q51777715
Multipotential differentiation of human anulus fibrosus cells: an in vitro study.Q54439265
Heritability of low back pain and the role of disc degenerationQ57256818
Apolipoprotein E Polymorphism: A New Genetic Marker of Hip Fracture RiskThe Study of Osteoporotic FracturesQ57616139
Expression and Distribution of Tumor Necrosis Factor Alpha in Human Lumbar Intervertebral Discs: A Study in Surgical Specimen and Autopsy ControlsQ63341178
A controlled immunohistochemical study of inflammatory cells in disc herniation tissueQ72653285
ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial treeQ72689998
Low back pain in relation to lumbar disc degenerationQ73522106
Association of bone mineral density with apolipoprotein E phenotypeQ73673405
Enhanced expression of matrix metalloproteinase-3, -12, and -13 mRNAs in the aortas of apolipoprotein E-deficient mice with advanced atherosclerosisQ78027366
Changes in mRNA and protein levels of proteoglycans of the anulus fibrosus and nucleus pulposus during intervertebral disc degenerationQ78413360
Is greater lumbar vertebral BMD associated with more disk degeneration? A study using µCT and discographyQ84590557
P433issue2
P921main subjectknockout mouseQ1364740
P304page(s)210-217
P577publication date2012-08-22
P1433published inJournal of Orthopaedic ResearchQ6295700
P1476titleIntervertebral disc degeneration and ectopic bone formation in apolipoprotein E knockout mice
P478volume31

Reverse relations

cites work (P2860)
Q30252208Animal models for disc degeneration-an update
Q30413145Annulus fibrosus cell characteristics are a potential source of intervertebral disc pathogenesis
Q89829122Loss of tenomodulin expression is a risk factor for age-related intervertebral disc degeneration
Q30252648Nanoparticle fullerol alleviates radiculopathy via NLRP3 inflammasome and neuropeptides
Q41286398Possible involvement of the oxLDL/LOX-1 system in the pathogenesis and progression of human intervertebral disc degeneration or herniation
Q30277122miR-221 attenuates the osteogenic differentiation of human annulus fibrosus cells

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