Impact of proton pump inhibitor therapy on the efficacy of clopidogrel in the CAPRIE and CREDO trials

scientific article

Impact of proton pump inhibitor therapy on the efficacy of clopidogrel in the CAPRIE and CREDO trials is …
instance of (P31):
scholarly articleQ13442814
meta-analysisQ815382

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P356DOI10.1161/JAHA.112.004564
P932PMC publication ID3603228
P698PubMed publication ID23525436

P50authorEric J. TopolQ5387640
Peter B. BergerQ7172602
Steve SteinhublQ57450607
P2093author name stringSteven P Dunn
Richard J Charnigo
Deborah Bauer
P2860cites workEffects of pantoprazole and esomeprazole on platelet inhibition by clopidogrelQ46199177
Impact of proton pump inhibitors on the antiplatelet effects of clopidogrel.Q50357085
Clinical Events as a Function of Proton Pump Inhibitor Use, Clopidogrel Use, and Cytochrome P450 2C19 Genotype in a Large Nationwide Cohort of Acute Myocardial InfarctionQ57243377
Concomitant use of clopidogrel and proton pump inhibitors is not associated with major adverse cardiovascular events following coronary stent implantationQ57300220
Negative inotropy of the gastric proton pump inhibitor pantoprazole in myocardium from humans and rabbits: evaluation of mechanismsQ80495498
ACCF/ACG/AHA 2010 Expert Consensus Document on the concomitant use of proton pump inhibitors and thienopyridines: a focused update of the ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy andQ82364672
Differential Effects of Omeprazole and Pantoprazole on the Pharmacodynamics and Pharmacokinetics of Clopidogrel in Healthy Subjects: Randomized, Placebo-Controlled, Crossover Comparison StudiesQ85036168
Use of proton pump inhibitors and mortality among institutionalized older peopleQ85103495
Meta-analysis in clinical trialsQ27860779
Benefit of clopidogrel over aspirin is amplified in patients with a history of ischemic eventsQ28166894
Early and sustained dual oral antiplatelet therapy following percutaneous coronary intervention: a randomized controlled trialQ28194232
Lack of adverse clopidogrel-atorvastatin clinical interaction from secondary analysis of a randomized, placebo-controlled clopidogrel trialQ28199508
A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE). CAPRIE Steering CommitteeQ29620666
Clopidogrel: review of bioanalytical methods, pharmacokinetics/pharmacodynamics, and update on recent trends in drug-drug interaction studiesQ33378137
Influence of omeprazole on the antiplatelet action of clopidogrel associated with aspirin: the randomized, double-blind OCLA (Omeprazole CLopidogrel Aspirin) studyQ34009506
Atorvastatin reduces the ability of clopidogrel to inhibit platelet aggregation: a new drug-drug interactionQ34168972
A population-based study of the drug interaction between proton pump inhibitors and clopidogrelQ34603772
Clopidogrel with or without omeprazole in coronary artery diseaseQ34660303
Risk of adverse outcomes associated with concomitant use of clopidogrel and proton pump inhibitors following acute coronary syndromeQ34956075
Outcomes with concurrent use of clopidogrel and proton-pump inhibitors: a cohort studyQ35222839
Pharmacodynamic effect and clinical efficacy of clopidogrel and prasugrel with or without a proton-pump inhibitor: an analysis of two randomised trialsQ37590925
The prevalence of co-administration of clopidogrel and proton pump inhibitors.Q37894155
Association of proton pump inhibitor use on cardiovascular outcomes with clopidogrel and ticagrelor: insights from the platelet inhibition and patient outcomes trialQ38477257
Increased Use of Acid‐Suppressing Drugs Before the Occurrence of Ischemic Events: A Potential Source of Confounding in Recent Observational StudiesQ42875458
Proton-pump inhibitors are associated with increased cardiovascular risk independent of clopidogrel use: a nationwide cohort studyQ42882409
Impact of proton pump inhibitors on the effectiveness of clopidogrel after coronary stent placement: the clopidogrel Medco outcomes studyQ42961046
P433issue1
P921main subjectclopidogrelQ410237
P304page(s)e004564
P577publication date2013-01-15
P1433published inJournal of the American Heart Association: Cardiovascular and Cerebrovascular DiseaseQ19880670
P1476titleImpact of proton pump inhibitor therapy on the efficacy of clopidogrel in the CAPRIE and CREDO trials
P478volume2