Introduction of a point mutation into the mouse genome by homologous recombination in embryonic stem cells using a replacement type vector with a selectable marker

scientific article

Introduction of a point mutation into the mouse genome by homologous recombination in embryonic stem cells using a replacement type vector with a selectable marker is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/NAR/21.11.2613
P932PMC publication ID309589
P698PubMed publication ID8392702
P5875ResearchGate publication ID14806009

P50authorMiguel A JapónQ40263959
P2093author name stringM Rubinstein
M J Low
P2860cites workTargeted mutation of the DNA methyltransferase gene results in embryonic lethalityQ28131773
The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brainQ28586297
Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar developmentQ28593581
Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in miceQ29547898
Simplified mammalian DNA isolation procedureQ29618648
An animal model for cystic fibrosis made by gene targetingQ33970549
Limited bidirectional activity of two housekeeping gene promoters: human HPRT and PGK.Q34332031
Testing an "in-out" targeting procedure for making subtle genomic modifications in mouse embryonic stem cellsQ36958779
Homologous recombination in mammalian cellsQ38763375
Regulation of proopiomelanocortin gene expression in pituitaryQ39210658
Neuropeptides derived from pro-opiocortin: behavioral, physiological, and neurochemical effectsQ40087121
Investigation of coelectroporation as a method for introducing small mutations into embryonic stem cellsQ40655136
Animal model of Gaucher's disease from targeted disruption of the mouse glucocerebrosidase geneQ44601366
Neuronal expression of chimeric genes in transgenic mice.Q45984030
The mouse genome contains two nonallelic pro-opiomelanocortin genesQ48396982
Tissue-specific posttranslational processing of pre-prosomatostatin encoded by a metallothionein-somatostatin fusion gene in transgenic miceQ48494752
Disruption of the Hox-1.6 homeobox gene results in defects in a region corresponding to its rostral domain of expressionQ48654359
Production of chimaeric mice containing embryonic stem (ES) cells carrying a homoeobox Hox 1.1 allele mutated by homologous recombination.Q52246995
Parental imprinting of the mouse insulin-like growth factor II gene.Q55052428
A Mammary-Specific Promoter Directs Expression of Growth Hormone not only to the Mammary Gland, but also to Bergman Glia Cells in Transgenic MiceQ57174281
Introduction of a subtle mutation into the Hox-2.6 locus in embryonic stem cellsQ59064557
P433issue11
P407language of work or nameEnglishQ1860
P304page(s)2613-2617
P577publication date1993-06-01
P1433published inNucleic Acids ResearchQ135122
P1476titleIntroduction of a point mutation into the mouse genome by homologous recombination in embryonic stem cells using a replacement type vector with a selectable marker
P478volume21

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cites work (P2860)
Q37626387Absence of opioid stress-induced analgesia in mice lacking beta-endorphin by site-directed mutagenesis
Q44497322Beta-endorphin modulates the acute response to a social conflict in male mice but does not play a role in stress-induced changes in sleep.
Q40382136Genetic knockouts in mice: an update
Q44233550Increased splenocyte proliferative response and cytokine production in beta-endorphin-deficient mice
Q44633543Reduced sodium appetite and increased oxytocin gene expression in mutant mice lacking β-endorphin
Q36028536Somatostatin is required for masculinization of growth hormone-regulated hepatic gene expression but not of somatic growth
Q37685031The genetics of pain and pain inhibition
Q96772559Universal Southern blot protocol with cold or radioactive probes for the validation of alleles obtained by homologous recombination

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