RIN3 is a negative regulator of mast cell responses to SCF.

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RIN3 is a negative regulator of mast cell responses to SCF. is …
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scholarly articleQ13442814

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P819ADS bibcode2012PLoSO...749615J
P356DOI10.1371/JOURNAL.PONE.0049615
P932PMC publication ID3502454
P698PubMed publication ID23185384
P5875ResearchGate publication ID233775559

P2093author name stringGeorge C Prendergast
Noriyuki Kasahara
John Colicelli
Christine Janson
P2860cites workRin1 is a negative regulator of the IL3 receptor signal transduction pathways.Q53599362
Continual expression of Rab5(Q79L) causes a ligand-independent EGFR internalization and diminishes EGFR activityQ80354398
Bin2, a functionally nonredundant member of the BAR adaptor gene familyQ22254645
Rin1 interacts with signal-transducing adaptor molecule (STAM) and mediates epidermal growth factor receptor trafficking and degradationQ24301513
RIN1 is an ABL tyrosine kinase activator and a regulator of epithelial-cell adhesion and migrationQ24301773
Signaling by Kit protein-tyrosine kinase--the stem cell factor receptorQ24318673
Protein binding and signaling properties of RIN1 suggest a unique effector functionQ24319548
Let's go bananas: revisiting the endocytic BAR codeQ24635636
Roles of RabGEF1/Rabex-5 domains in regulating Fc epsilon RI surface expression and Fc epsilon RI-dependent responses in mast cellsQ24674977
A simplified system for generating recombinant adenovirusesQ24682328
Mast cells in inflammatory arthritisQ24798636
The role of mast cells in allergic inflammationQ27003571
A new member of the amphiphysin family connecting endocytosis and signal transduction pathwaysQ28240505
Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cellsQ28277030
Signal transduction via the stem cell factor receptor/c-KitQ28291675
RabGEF1 regulates stem cell factor/c-Kit-mediated signaling events and biological responses in mast cellsQ28586055
Rabs and their effectors: achieving specificity in membrane trafficQ29619989
A novel Rab5 GDP/GTP exchange factor complexed to Rabaptin-5 links nucleotide exchange to effector recruitment and functionQ29620529
RIN3: a novel Rab5 GEF interacting with amphiphysin II involved in the early endocytic pathwayQ30164512
Characterization of a novel human mast cell line that responds to stem cell factor and expresses functional FcεRIQ30428097
RINL, guanine nucleotide exchange factor Rab5-subfamily, is involved in the EphA8-degradation pathway with odinQ31047089
The biology of stem cell factor and its receptor C-kitQ33785129
Efficient gene transfer into human CD34(+) cells by a retargeted adenovirus vectorQ33799667
Rab GTPases coordinate endocytosisQ33816001
c-Kit and c-kit mutations in mastocytosis and other hematological diseases.Q33835586
BAR the door: cancer suppression by amphiphysin-like genesQ33870256
Effect of the tyrosine kinase inhibitor STI571 in a patient with a metastatic gastrointestinal stromal tumorQ33941495
Ras-activated endocytosis is mediated by the Rab5 guanine nucleotide exchange activity of RIN1.Q34101310
Glivec (STI571, imatinib), a rationally developed, targeted anticancer drugQ34139151
The interface of receptor trafficking and signallingQ34394434
Rin1 regulates insulin receptor signal transduction pathwaysQ34491332
Rabenosyn-5 defines the fate of the transferrin receptor following clathrin-mediated endocytosisQ35779085
Stem cell factor-induced airway hyperreactivity in allergic and normal miceQ35786893
Regulation of mast cell responses in health and diseaseQ36092456
Feedback regulation of Ras signaling by Rabex-5-mediated ubiquitinationQ36217483
Structure and regulation of Kit protein-tyrosine kinase--the stem cell factor receptorQ36287291
Integration of transforming growth factor beta and RAS signaling silences a RAB5 guanine nucleotide exchange factor and enhances growth factor-directed cell migrationQ36483438
RIN1 orchestrates the activation of RAB5 GTPases and ABL tyrosine kinases to determine the fate of EGFR.Q36619492
Mast cells and mastocytosisQ36835143
The Rab5 guanylate exchange factor Rin1 regulates endocytosis of the EphA4 receptor in mature excitatory neuronsQ36858652
Regulation of secretory vesicle traffic by Rab small GTPasesQ37251862
Rabex-5 is a Rab22 effector and mediates a Rab22-Rab5 signaling cascade in endocytosisQ37420461
AMPH-1/Amphiphysin/Bin1 functions with RME-1/Ehd1 in endocytic recyclingQ37460208
Membrane shaping by the Bin/amphiphysin/Rvs (BAR) domain protein superfamilyQ37902570
Rab5a regulates surface expression of FcεRI and functional activation in mast cellsQ38335518
The SRC homology 2 domain of Rin1 mediates its binding to the epidermal growth factor receptor and regulates receptor endocytosisQ38353980
The antitumor activity of homoharringtonine against human mast cells harboring the KIT D816V mutationQ39755254
Cell proliferation and epidermal growth factor signaling in non-small cell lung adenocarcinoma cell lines are dependent on Rin1.Q39830464
Identification of MCL1 as a novel target in neoplastic mast cells in systemic mastocytosis: inhibition of mast cell survival by MCL1 antisense oligonucleotides and synergism with PKC412.Q40207428
Characterization of novel stem cell factor responsive human mast cell lines LAD 1 and 2 established from a patient with mast cell sarcoma/leukemia; activation following aggregation of FcepsilonRI or FcgammaRI.Q40640528
Amphiphysin 2 (Bin1) and T-tubule biogenesis in muscleQ40710117
Rab5 regulates the dynamics of early endosome fusionQ41146537
Establishment of an immature mast cell line from a patient with mast cell leukemiaQ41296878
Efficacy of imatinib mesylate (STI571) treatment for a patient with rheumatoid arthritis developing chronic myelogenous leukemiaQ44630894
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectmast cellQ191989
P304page(s)e49615
P577publication date2012-11-20
P1433published inPLOS OneQ564954
P1476titleRIN3 is a negative regulator of mast cell responses to SCF.
P478volume7

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cites work (P2860)
Q64057094A Genome-Wide Analysis of the Penumbral Volume in Inbred Mice following Middle Cerebral Artery Occlusion
Q38554818Biology and Treatment of Paget's Disease of Bone
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Q28080897Dynamic self-guiding analysis of Alzheimer's disease
Q88205441Genetics of Paget's disease of bone
Q33889172Identification of rs7350481 at chromosome 11q23.3 as a novel susceptibility locus for metabolic syndrome in Japanese individuals by an exome-wide association study
Q29416987Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis

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