The many mechanisms of viral membrane fusion proteins.

scientific article

The many mechanisms of viral membrane fusion proteins. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1007/3-540-26764-6_2
P932PMC publication ID7122167
P698PubMed publication ID15609500

P2093author name stringJ M White
S E Delos
H E Park
L J Earp
P2860cites workLipid-anchored influenza hemagglutinin promotes hemifusion, not complete fusionQ44633908
Electron microscopy of the human respiratory syncytial virus fusion protein and complexes that it forms with monoclonal antibodiesQ45742418
Temperature dependence of fusion by sendai virusQ45742427
Oligomerization, secretion, and biological function of an anchor-free parainfluenza virus type 2 (PI2) fusion proteinQ45742724
Mutations in the glycoprotein of viral haemorrhagic septicaemia virus that affect virulence for fish and the pH threshold for membrane fusionQ45749135
Importance of the intracytoplasmic domain of the simian immunodeficiency virus (SIV) envelope glycoprotein for pathogenesis.Q45752054
Interaction of peptide fragment 828-848 of the envelope glycoprotein of human immunodeficiency virus type I with lipid bilayersQ45773640
Kinetics and pH dependence of acid-induced structural changes in the lymphocytic choriomeningitis virus glycoprotein complexQ45785753
Membrane fusion activity of the influenza virus hemagglutinin. The low pH-induced conformational change.Q45828248
Effects of low pH on influenza virus. Activation and inactivation of the membrane fusion capacity of the hemagglutininQ45829893
Maturation of murine leukemia virus env proteins in the absence of other viral proteinsQ45838350
A trimeric structural domain of the HIV-1 transmembrane glycoprotein.Q54155492
Evidence for H(+)-induced insertion of influenza hemagglutinin HA2 N-terminal segment into viral membraneQ72068502
Liposome destabilization induced by the HIV-1 fusion peptide effect of a single amino acid substitutionQ72165328
Influenza hemagglutinin-mediated membrane fusion: influence of receptor binding on the lag phase preceding fusionQ72528362
Retroviral entry mediated by receptor priming and low pH triggering of an envelope glycoproteinQ73270498
A leucine zipper-like sequence from the cytoplasmic tail of the HIV-1 envelope glycoprotein binds and perturbs lipid bilayersQ73309597
Acylation of the influenza hemagglutinin modulates fusion activityQ77165158
The protein coat in membrane fusion: lessons from fissionQ77869246
HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled ReceptorQ22242268
Role of the hemagglutinin-neuraminidase protein in the mechanism of paramyxovirus-cell membrane fusionQ24538786
Fusion of Rous sarcoma virus with host cells does not require exposure to low pHQ24655687
Structure of dengue virus: implications for flavivirus organization, maturation, and fusionQ24736810
The central proline of an internal viral fusion peptide serves two important rolesQ27469628
Membrane interface-interacting sequences within the ectodomain of the human immunodeficiency virus type 1 envelope glycoprotein: putative role during viral fusionQ27469690
Mapping of functional elements in the stem-anchor region of tick-borne encephalitis virus envelope protein EQ27469713
An epitope of the Semliki Forest virus fusion protein exposed during virus-membrane fusionQ27469752
Mutational Evidence for an Internal Fusion Peptide in Flavivirus Envelope Protein EQ27469788
Role of metastability and acidic pH in membrane fusion by tick-borne encephalitis virus.Q27469927
The fusion peptide of Semliki Forest virus associates with sterol-rich membrane domainsQ27472848
Membrane interactions of the tick-borne encephalitis virus fusion protein E at low pH.Q27472865
Membrane fusion tropism and heterotypic functional activities of the Nipah virus and Hendra virus envelope glycoproteinsQ27472931
The Coronavirus Spike Protein Is a Class I Virus Fusion Protein: Structural and Functional Characterization of the Fusion Core ComplexQ27477706
Oligomeric rearrangement of tick-borne encephalitis virus envelope proteins induced by an acidic pHQ27478446
Structural requirements for low-pH-induced rearrangements in the envelope glycoprotein of tick-borne encephalitis virusQ27480753
Membrane fusion process of Semliki Forest virus. I: Low pH-induced rearrangement in spike protein quaternary structure precedes virus penetration into cellsQ27485691
Viral and cellular membrane fusion proteinsQ34208540
Common properties of fusion peptides from diverse systemsQ34293662
Viral fusion peptides: a tool set to disrupt and connect biological membranesQ34293668
Caveolae as portals of entry for microbesQ34328519
Soluble receptor potentiates receptor-independent infection by murine coronavirusQ34329104
Segregation of CD4 and CXCR4 into distinct lipid microdomains in T lymphocytes suggests a mechanism for membrane destabilization by human immunodeficiency virusQ34330529
The machinery for flavivirus fusion with host cell membranesQ34331567
Truncation of the cytoplasmic domain induces exposure of conserved regions in the ectodomain of human immunodeficiency virus type 1 envelope proteinQ34332519
Influenza fusion peptidesQ34332538
Dissection of human immunodeficiency virus type 1 entry with neutralizing antibodies to gp41 fusion intermediatesQ34341098
Mutagenic stabilization and/or disruption of a CD4-bound state reveals distinct conformations of the human immunodeficiency virus type 1 gp120 envelope glycoproteinQ34347265
Newcastle disease virus HN protein alters the conformation of the F protein at cell surfacesQ34352422
Covalent modifications of the ebola virus glycoproteinQ34354004
Sensitivity of HIV-1 to entry inhibitors correlates with envelope/coreceptor affinity, receptor density, and fusion kineticsQ34415921
Mutations in the cytoplasmic domain of a paramyxovirus fusion glycoprotein rescue syncytium formation and eliminate the hemagglutinin-neuraminidase protein requirement for membrane fusionQ34462207
Cytoplasmic tail of Moloney murine leukemia virus envelope protein influences the conformation of the extracellular domain: implications for mechanism of action of the R PeptideQ34464572
Human T-cell leukemia virus type 1 envelope-mediated syncytium formation can be activated in resistant Mammalian cell lines by a carboxy-terminal truncation of the envelope cytoplasmic domainQ34464923
Peptides trap the human immunodeficiency virus type 1 envelope glycoprotein fusion intermediate at two sitesQ34466260
A point mutation in the transmembrane domain of the hemagglutinin of influenza virus stabilizes a hemifusion intermediate that can transit to fusion.Q34775394
HIV-1 envelope proteins complete their folding into six-helix bundles immediately after fusion pore formationQ34812952
Lipid rafts and assembly of enveloped virusesQ34852370
Human Immunodeficiency Virus Type 1 Env with an Intersubunit Disulfide Bond Engages Coreceptors but Requires Bond Reduction after Engagement To Induce FusionQ34977118
Insider information: what viruses tell us about endocytosisQ35189406
Palmitoylation of the HIV-1 envelope glycoprotein is critical for viral infectivityQ35566715
Temperature dependence of cell-cell fusion induced by the envelope glycoprotein of human immunodeficiency virus type 1.Q35833860
Quantitative measurement of paramyxovirus fusion: differences in requirements of glycoproteins between simian virus 5 and human parainfluenza virus 3 or Newcastle disease virusQ35849734
Analysis of the cell fusion activities of chimeric simian immunodeficiency virus-murine leukemia virus envelope proteins: inhibitory effects of the R peptideQ35853520
Domains of the human immunodeficiency virus type 1 matrix and gp41 cytoplasmic tail required for envelope incorporation into virions.Q35853659
Association of the parainfluenza virus fusion and hemagglutinin-neuraminidase glycoproteins on cell surfacesQ35875690
Detection of an interaction between the HN and F proteins in Newcastle disease virus-infected cellsQ35890850
The transmembrane domain in viral fusion: essential role for a conserved glycine residue in vesicular stomatitis virus G proteinQ36001197
Fusion of Semliki forest virus with the plasma membrane can be induced by low pH.Q36201795
Studies on the mechanism of membrane fusion: site-specific mutagenesis of the hemagglutinin of influenza virusQ36214055
Membrane fusion of Semliki Forest virus involves homotrimers of the fusion proteinQ27486203
Structural basis for paramyxovirus-mediated membrane fusionQ27617867
N- and C-terminal residues combine in the fusion-pH influenza hemagglutinin HA(2) subunit to form an N cap that terminates the triple-stranded coiled coilQ27619272
Inhibiting HIV-1 entry: discovery of D-peptide inhibitors that target the gp41 coiled-coil pocketQ27619965
The structure of the fusion glycoprotein of Newcastle disease virus suggests a novel paradigm for the molecular mechanism of membrane fusionQ27631011
The Fusion glycoprotein shell of Semliki Forest virus: an icosahedral assembly primed for fusogenic activation at endosomal pHQ27631190
Membrane structure and fusion-triggering conformational change of the fusion domain from influenza hemagglutininQ27633701
The membrane-proximal tryptophan-rich region of the HIV glycoprotein, gp41, forms a well-defined helix in dodecylphosphocholine micellesQ27635152
An antibody that prevents the hemagglutinin low pH fusogenic transitionQ27638286
Structure of the dengue virus envelope protein after membrane fusionQ27643009
Conformational change and protein-protein interactions of the fusion protein of Semliki Forest virusQ27643010
Structure of a flavivirus envelope glycoprotein in its low-pH-induced membrane fusion conformationQ27643140
The envelope glycoprotein from tick-borne encephalitis virus at 2 A resolutionQ27730234
Structure of influenza haemagglutinin at the pH of membrane fusionQ27730888
Core structure of gp41 from the HIV envelope glycoproteinQ27736064
Atomic structure of the ectodomain from HIV-1 gp41Q27738021
Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibodyQ27759364
Structure of the hemagglutinin precursor cleavage site, a determinant of influenza pathogenicity and the origin of the labile conformationQ27766025
Crystal structure of the Ebola virus membrane fusion subunit, GP2, from the envelope glycoprotein ectodomainQ27766228
Receptor binding and membrane fusion in virus entry: the influenza hemagglutininQ27861017
Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3 A resolutionQ28131812
The structural biology of type I viral membrane fusionQ28188215
HIV entry and its inhibitionQ28273919
Membrane fusion machines of paramyxoviruses: capture of intermediates of fusionQ28345073
Structure-based identification of small molecule antiviral compounds targeted to the gp41 core structure of the human immunodeficiency virus type 1Q28371845
Selection of gp41-mediated HIV-1 cell entry inhibitors from biased combinatorial libraries of non-natural binding elementsQ28373387
Evidence that the transition of HIV-1 gp41 into a six-helix bundle, not the bundle configuration, induces membrane fusionQ28646673
A spring-loaded mechanism for the conformational change of influenza hemagglutininQ28646856
Structural features of membrane fusion between influenza virus and liposome as revealed by quick-freezing electron microscopyQ28646869
Capture of an early fusion-active conformation of HIV-1 gp41Q28646880
Mechanisms of viral membrane fusion and its inhibitionQ29616090
Membrane fusionQ29618140
Structure and function of sphingolipid- and cholesterol-rich membrane raftsQ29618518
Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41-mediated virus entryQ29620710
A specific point mutant at position 1 of the influenza hemagglutinin fusion peptide displays a hemifusion phenotypeQ30304191
Mutations within the putative membrane-spanning domain of the simian immunodeficiency virus transmembrane glycoprotein define the minimal requirements for fusion, incorporation, and infectivityQ33846366
Cellular membrane-binding ability of the C-terminal cytoplasmic domain of human immunodeficiency virus type 1 envelope transmembrane protein gp41.Q33847059
Mutations in the cytoplasmic tail of murine leukemia virus envelope protein suppress fusion inhibition by R peptideQ33850746
Activation of membrane fusion by murine leukemia viruses is controlled in cis or in trans by interactions between the receptor-binding domain and a conserved disulfide loop of the carboxy terminus of the surface glycoproteinQ33851195
Deletion of the cytoplasmic tail of the fusion protein of the paramyxovirus simian virus 5 affects fusion pore enlargementQ33852113
Specific roles for lipids in virus fusion and exit. Examples from the alphaviruses.Q33917125
Membrane fusion activity of influenza virus.Q33927846
Role of the N-terminal peptides of viral envelope proteins in membrane fusion.Q33933461
Cleavage of the human respiratory syncytial virus fusion protein at two distinct sites is required for activation of membrane fusionQ33934074
Membrane fusion of Semliki Forest virus in a model system: correlation between fusion kinetics and structural changes in the envelope glycoproteinQ34043702
Measles viruses with altered envelope protein cytoplasmic tails gain cell fusion competence.Q34069549
Observation of a membrane fusion intermediate structureQ34149361
Proper spacing between heptad repeat B and the transmembrane domain boundary of the paramyxovirus SV5 F protein is critical for biological activityQ41071200
The role of the cytoplasmic tail region of influenza virus hemagglutinin in formation and growth of fusion poresQ41093333
Entry of Semliki forest virus into cells: effects of concanamycin A and nigericin on viral membrane fusion and infection.Q41133527
A new mechanism for the neutralization of enveloped viruses by antiviral antibodyQ41352659
Role of the fusion peptide sequence in initial stages of influenza hemagglutinin-induced cell fusion.Q41554310
Inhibition of the fusion-inducing conformational change of influenza hemagglutinin by benzoquinones and hydroquinonesQ41565125
Molecular organization of a recombinant subviral particle from tick-borne encephalitis virusQ41630846
Introduction of intersubunit disulfide bonds in the membrane-distal region of the influenza hemagglutinin abolishes membrane fusion activityQ41639247
What studies of fusion peptides tell us about viral envelope glycoprotein-mediated membrane fusion (review).Q41658185
The cytoplasmic tail of HIV-1 gp160 contains regions that associate with cellular membranesQ41702321
The pH independence of mammalian retrovirus infectionQ41738977
pH-independent HIV entry into CD4-positive T cells via virus envelope fusion to the plasma membraneQ41764642
A molecular model for membrane fusion based on solution studies of an amphiphilic peptide from HIV gp41Q42598413
Membrane fusion activity of tick-borne encephalitis virus and recombinant subviral particles in a liposomal model systemQ42997821
Fusion of enveloped viruses with cells and liposomes. Activity and inactivationQ43635160
Sphingomyelin and cholesterol promote HIV-1 gp41 pretransmembrane sequence surface aggregation and membrane restructuring.Q43945296
Sphingolipid and cholesterol dependence of alphavirus membrane fusion. Lack of correlation with lipid raft formation in target liposomesQ44077405
Fusion peptides derived from the HIV type 1 glycoprotein 41 associate within phospholipid membranes and inhibit cell-cell Fusion. Structure-function study.Q44184585
VSV transmembrane domain (TMD) peptide promotes PEG-mediated fusion of liposomes in a conformationally sensitive fashionQ44244220
Regulation of fusion activity by the cytoplasmic domain of a paramyxovirus F proteinQ44373009
Effect of proteolytic processing at two distinct sites on shape and aggregation of an anchorless fusion protein of human respiratory syncytial virus and fate of the intervening segment.Q44602073
Critical role for the cysteines flanking the internal fusion peptide of avian sarcoma/leukosis virus envelope glycoproteinQ30306131
The transmembrane domain of influenza hemagglutinin exhibits a stringent length requirement to support the hemifusion to fusion transitionQ30306248
Structure and function of membrane fusion peptidesQ30310337
The avian retrovirus avian sarcoma/leukosis virus subtype A reaches the lipid mixing stage of fusion at neutral pH.Q30310511
Thermodynamics of fusion peptide-membrane interactionsQ30310922
Leash in the groove mechanism of membrane fusionQ30311919
Sequential roles of receptor binding and low pH in forming prehairpin and hairpin conformations of a retroviral envelope glycoproteinQ30433973
Synchronized activation and refolding of influenza hemagglutinin in multimeric fusion machinesQ30441948
Specific single or double proline substitutions in the "spring-loaded" coiled-coil region of the influenza hemagglutinin impair or abolish membrane fusion activityQ30442103
Dilation of the human immunodeficiency virus-1 envelope glycoprotein fusion pore revealed by the inhibitory action of a synthetic peptide from gp41Q30442126
Activation of a retroviral membrane fusion protein: soluble receptor-induced liposome binding of the ALSV envelope glycoproteinQ30442135
Inner but not outer membrane leaflets control the transition from glycosylphosphatidylinositol-anchored influenza hemagglutinin-induced hemifusion to full fusionQ30442161
Membrane fusion mediated by the influenza virus hemagglutinin requires the concerted action of at least three hemagglutinin trimersQ30442203
Structure-based identification of an inducer of the low-pH conformational change in the influenza virus hemagglutinin: irreversible inhibition of infectivityQ30452569
New insights into the spring-loaded conformational change of influenza virus hemagglutininQ30452958
Mutational analysis of the candidate internal fusion peptide of the avian leukosis and sarcoma virus subgroup A envelope glycoprotein.Q30453530
Receptor-triggered membrane association of a model retroviral glycoproteinQ30454419
Virus-cell and cell-cell fusionQ30469833
Peptide and non-peptide HIV fusion inhibitorsQ30831361
Role of cholesterol in human immunodeficiency virus type 1 envelope protein-mediated fusion with host cellsQ30865013
Mode of action of an antiviral peptide from HIV-1. Inhibition at a post-lipid mixing stageQ31454800
The catalytic activity of protein disulfide isomerase is involved in human immunodeficiency virus envelope-mediated membrane fusion after CD4 cell bindingQ31954340
Structural basis for membrane fusion by enveloped virusesQ33637921
Rabies virus-induced membrane fusionQ33637927
pH-dependent changes in photoaffinity labeling patterns of the H1 influenza virus hemagglutinin by using an inhibitor of viral fusion.Q33652712
A conserved tryptophan-rich motif in the membrane-proximal region of the human immunodeficiency virus type 1 gp41 ectodomain is important for Env-mediated fusion and virus infectivity.Q33654081
A proline-rich motif downstream of the receptor binding domain modulates conformation and fusogenicity of murine retroviral envelopesQ33786094
Role of hemagglutinin surface density in the initial stages of influenza virus fusion: lack of evidence for cooperativityQ33799995
Mutational analysis of conserved domains within the cytoplasmic tail of gp41 from human immunodeficiency virus type 1: effects on glycoprotein incorporation and infectivityQ33812739
Conformational intermediates and fusion activity of influenza virus hemagglutinin.Q33813444
Interaction of peptides with sequences from the Newcastle disease virus fusion protein heptad repeat regionsQ33815821
Role of the membrane-proximal domain in the initial stages of human immunodeficiency virus type 1 envelope glycoprotein-mediated membrane fusion.Q33815984
Mutational analysis of the putative fusion domain of Ebola virus glycoprotein.Q33821928
Mechanisms of mutations inhibiting fusion and infection by Semliki Forest virus.Q36237272
Dilation of the influenza hemagglutinin fusion pore revealed by the kinetics of individual cell-cell fusion eventsQ36237488
A single point mutation controls the cholesterol dependence of Semliki Forest virus entry and exitQ36254866
Membrane fusion mediated by baculovirus gp64 involves assembly of stable gp64 trimers into multiprotein aggregatesQ36256359
pH-dependent fusion between the Semliki Forest virus membrane and liposomesQ36392548
Mutations in the membrane-spanning domain of the human immunodeficiency virus envelope glycoprotein that affect fusion activity.Q36620954
Function of the cytoplasmic domain of a retroviral transmembrane protein: p15E-p2E cleavage activates the membrane fusion capability of the murine leukemia virus Env proteinQ36629882
Expression of the TM protein of Rous sarcoma virus in the absence of SU shows that this domain is capable of oligomerization and intracellular transportQ36632361
pH-independent murine leukemia virus ecotropic envelope-mediated cell fusion: implications for the role of the R peptide and p12E TM in viral entryQ36633601
Fusogenic mechanisms of enveloped-virus glycoproteins analyzed by a novel recombinant vaccinia virus-based assay quantitating cell fusion-dependent reporter gene activation.Q36634800
Intermonomer disulfide bonds impair the fusion activity of influenza virus hemagglutininQ36700712
A mutation in the human immunodeficiency virus type 1 transmembrane glycoprotein gp41 dominantly interferes with fusion and infectivityQ36756570
Influenza hemagglutinin is spring-loaded by a metastable native conformationQ36809584
The role of the membrane-spanning domain sequence in glycoprotein-mediated membrane fusionQ36906696
Peptides from conserved regions of paramyxovirus fusion (F) proteins are potent inhibitors of viral fusionQ37712954
Tight binding of influenza virus hemagglutinin to its receptor interferes with fusion pore dilationQ38360836
Inhibition of influenza virus hemagglutinin-mediated membrane fusion by a compound related to podocarpic acidQ38462263
Activation of vesicular stomatitis virus fusion with cells by pretreatment at low pH.Q39532421
An evolutionarily conserved positively charged amino acid in the putative membrane-spanning domain of the foamy virus envelope protein controls fusion activityQ39590982
Modification of the cytoplasmic domain of influenza virus hemagglutinin affects enlargement of the fusion poreQ39592707
Antibodies to CD9, a tetraspan transmembrane protein, inhibit canine distemper virus-induced cell-cell fusion but not virus-cell fusionQ39592728
Receptor binding transforms the surface subunit of the mammalian C-type retrovirus envelope protein from an inhibitor to an activator of fusionQ39604047
Human immunodeficiency virus type 1 uses lipid raft-colocalized CD4 and chemokine receptors for productive entry into CD4(+) T cellsQ39683422
Interactions between the transmembrane segments of the alphavirus E1 and E2 proteins play a role in virus budding and fusionQ39732657
Fatty acids on the A/USSR/77 influenza virus hemagglutinin facilitate the transition from hemifusion to fusion pore formationQ39752831
Vesicular stomatitis virus glycoprotein mutations that affect membrane fusion activity and abolish virus infectivity.Q39869009
Mutations in the putative fusion peptide of Semliki Forest virus affect spike protein oligomerization and virus assembly.Q39869725
Fusion of bovine leukemia virus with target cells monitored by R18 fluorescence and PCR assaysQ39877869
Functional analysis of the cytoplasmic tail of Moloney murine leukemia virus envelope proteinQ39879338
Localization of the labile disulfide bond between SU and TM of the murine leukemia virus envelope protein complex to a highly conserved CWLC motif in SU that resembles the active-site sequence of thiol-disulfide exchange enzymesQ39881687
Mutational analysis of the vesicular stomatitis virus glycoprotein G for membrane fusion domainsQ40045940
Stalk model of membrane fusion: solution of energy crisisQ40201228
Membrane structure of the human immunodeficiency virus gp41 fusion domain by molecular dynamics simulationQ40209529
Alphavirus and flavivirus glycoproteins: structures and functionsQ40541050
Membrane fusion and the alphavirus life cycleQ40551613
Pre-transmembrane sequence of Ebola glycoprotein. Interfacial hydrophobicity distribution and interaction with membranes.Q40568440
Completion of trimeric hairpin formation of influenza virus hemagglutinin promotes fusion pore opening and enlargementQ40612986
HIV-1 entry into T-cells is not dependent on CD4 and CCR5 localization to sphingolipid-enriched, detergent-resistant, raft membrane domainsQ40690112
Protein-disulfide isomerase-mediated reduction of two disulfide bonds of HIV envelope glycoprotein 120 occurs post-CXCR4 binding and is required for fusionQ40705636
Inhibitors of protein-disulfide isomerase prevent cleavage of disulfide bonds in receptor-bound glycoprotein 120 and prevent HIV-1 entry.Q40705642
Identification of R-peptides in envelope proteins of C-type retrovirusesQ40709996
Paramyxovirus fusion: a hypothesis for changesQ40767649
Endocytic entry of HIV-1.Q40855363
Fusion protein of the paramyxovirus SV5: destabilizing and stabilizing mutants of fusion activationQ40885459
Mutations in the Newcastle disease virus hemagglutinin-neuraminidase protein that interfere with its ability to interact with the homologous F protein in the promotion of fusionQ40981026
A core trimer of the paramyxovirus fusion protein: parallels to influenza virus hemagglutinin and HIV-1 gp41.Q41016283
P304page(s)25-66
P577publication date2005-01-01
P1433published inCurrent Topics in Microbiology and ImmunologyQ15752446
P1476titleThe many mechanisms of viral membrane fusion proteins
P478volume285

Reverse relations

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Q21558779IFITM proteins restrict viral membrane hemifusion
Q34651454Identification of an N-terminal trimeric coiled-coil core within arenavirus glycoprotein 2 permits assignment to class I viral fusion proteins
Q37384933Induction of cell-cell fusion by ectromelia virus is not inhibited by its fusion inhibitory complex
Q34963154Inhibition of Ebola virus entry by a C-peptide targeted to endosomes
Q24814238Inhibition of Henipavirus fusion and infection by heptad-derived peptides of the Nipah virus fusion glycoprotein
Q35101317Inhibition of hendra virus fusion.
Q34434940Inhibition of receptor binding stabilizes Newcastle disease virus HN and F protein-containing complexes
Q28294996Inner/Outer nuclear membrane fusion in nuclear pore assembly: biochemical demonstration and molecular analysis
Q33622464Insulin degrading enzyme induces a conformational change in varicella-zoster virus gE, and enhances virus infectivity and stability
Q38768365Integrin αvβ1 Modulation Affects Subtype B Avian Metapneumovirus Fusion Protein-mediated Cell-Cell Fusion and Virus Infection
Q27490540Interactions and Oligomerization of Hantavirus Glycoproteins
Q37067907Interfacial pre-transmembrane domains in viral proteins promoting membrane fusion and fission.
Q61818410Interferon-induced transmembrane protein 3 blocks fusion of sensitive but not resistant viruses by partitioning into virus-carrying endosomes
Q92242558Intracellular Vesicle Fusion Requires a Membrane-Destabilizing Peptide Located at the Juxtamembrane Region of the v-SNARE
Q35549868Intracellular curvature-generating proteins in cell-to-cell fusion.
Q35422927Intronic deletions of tva receptor gene decrease the susceptibility to infection by avian sarcoma and leukosis virus subgroup A.
Q36483877Jaagsiekte sheep retrovirus utilizes a pH-dependent endocytosis pathway for entry.
Q34507126Ligand-induced and nonfusogenic dissolution of a viral membrane
Q30476143Liposome reconstitution of a minimal protein-mediated membrane fusion machine
Q30248743MERS-CoV spike protein: Targets for vaccines and therapeutics
Q36215318Macrophage fusion: the making of osteoclasts and giant cells
Q36901510Mechanics of membrane fusion
Q27027678Mechanisms of coronavirus cell entry mediated by the viral spike protein
Q98155448Mechanistic insights of host cell fusion of SARS-CoV-1 and SARS-CoV-2 from atomic resolution structure and membrane dynamics
Q90219290Membrane Composition Modulates Fusion by Altering Membrane Properties and Fusion Peptide Structure
Q33770433Membrane Fusion Involved in Neurotransmission: Glimpse from Electron Microscope and Molecular Simulation
Q80516923Membrane activity of an amphiphilic alpha-helical membrane-proximal cytoplasmic domain of the MoMuLV envelope glycoprotein
Q34221609Membrane fusion and cell entry of XMRV are pH-independent and modulated by the envelope glycoprotein's cytoplasmic tail
Q38256285Membrane proteins of arterivirus particles: structure, topology, processing and function.
Q42280908Membrane requirement for folding of the herpes simplex virus 1 gB cytodomain suggests a unique mechanism of fusion regulation
Q30437943Membrane structures of the hemifusion-inducing fusion peptide mutant G1S and the fusion-blocking mutant G1V of influenza virus hemagglutinin suggest a mechanism for pore opening in membrane fusion
Q40304999Membrane-anchored inhibitory peptides capture human immunodeficiency virus type 1 gp41 conformations that engage the target membrane prior to fusion
Q40020345Membrane-proximal cytoplasmic domain of Moloney murine leukemia virus envelope tail facilitates fusion
Q42689581Multifaceted sequence-dependent and -independent roles for reovirus FAST protein cytoplasmic tails in fusion pore formation and syncytiogenesis.
Q30478481Multiple intermediates in SNARE-induced membrane fusion
Q34651205Murine leukemia virus R Peptide inhibits influenza virus hemagglutinin-induced membrane fusion
Q35754943Mutations in the DI-DII Linker of Human Parainfluenza Virus Type 3 Fusion Protein Result in Diminished Fusion Activity
Q38809753Mutations in the Leucine Zipper-Like Motif of the Human Parainfluenza Virus 3 Fusion Protein Impair Fusion Activity.
Q41921957NMR structure and localization of a large fragment of the SARS-CoV fusion protein: Implications in viral cell fusion.
Q41726816NMR structures and localization of the potential fusion peptides and the pre-transmembrane region of SARS-CoV: Implications in membrane fusion.
Q43255517Nipah virus entry can occur by macropinocytosis
Q81504869Opinion: Cell entry machines: a common theme in nature?
Q38006719Palmitoylation of virus proteins
Q36346778Paramyxovirus membrane fusion: lessons from the F and HN atomic structures
Q41855783Peptides released from reovirus outer capsid form membrane pores that recruit virus particles.
Q45433900Pleiotropic mechanisms of virus survival and persistence
Q34202362Poxvirus multiprotein entry-fusion complex
Q37640977Poxvirus proteomics and virus-host protein interactions
Q36090006Primate lentiviruses are differentially inhibited by interferon-induced transmembrane proteins.
Q33373579Protein intrinsic disorder toolbox for comparative analysis of viral proteins
Q42176996Punctuated evolution of influenza virus neuraminidase (A/H1N1) under opposing migration and vaccination pressures
Q40229048Quantitative comparison of the efficiency of antibodies against S1 and S2 subunit of SARS coronavirus spike protein in virus neutralization and blocking of receptor binding: implications for the functional roles of S2 subunit
Q30479669Rapid membrane fusion of individual virus particles with supported lipid bilayers.
Q33263085Refolding of a paramyxovirus F protein from prefusion to postfusion conformations observed by liposome binding and electron microscopy
Q34917410Reovirus FAST protein transmembrane domains function in a modular, primary sequence-independent manner to mediate cell-cell membrane fusion.
Q35128812Residue-level resolution of alphavirus envelope protein interactions in pH-dependent fusion
Q27481481Role of Endocytosis and Low pH in Murine Hepatitis Virus Strain A59 Cell Entry
Q40002207Role of endocytosis and cathepsin-mediated activation in Nipah virus entry
Q30439990Role of endosomal cathepsins in entry mediated by the Ebola virus glycoprotein
Q42638118Role of the cytoplasmic tail domains of Bunyamwera orthobunyavirus glycoproteins Gn and Gc in virus assembly and morphogenesis
Q37033266Role of thiol/disulfide exchange in newcastle disease virus entry
Q52563510Rotation-Activated and Cooperative Zipping Characterize Class I Viral Fusion Protein Dynamics.
Q27477540Site-Directed Antibodies against the Stem Region Reveal Low pH-Induced Conformational Changes of the Semliki Forest Virus Fusion Protein
Q35785110Spring-loaded heptad repeat residues regulate the expression and activation of paramyxovirus fusion protein
Q39462591Spring-loaded model revisited: paramyxovirus fusion requires engagement of a receptor binding protein beyond initial triggering of the fusion protein
Q30447936Stoichiometry of envelope glycoprotein trimers in the entry of human immunodeficiency virus type 1
Q24649949Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses
Q29618168Structural basis of West Nile virus neutralization by a therapeutic antibody
Q27481675Structural basis of viral invasion: lessons from paramyxovirus F
Q45421033Structure of the parainfluenza virus 5 F protein in its metastable, prefusion conformation
Q33855371Structure of the uncleaved ectodomain of the paramyxovirus (hPIV3) fusion protein
Q27680499Structure-Based Design of a Fusion Glycoprotein Vaccine for Respiratory Syncytial Virus
Q27487974Structures and Mechanisms of Viral Membrane Fusion Proteins: Multiple Variations on a Common Theme
Q45416737Structures and polymorphic interactions of two heptad-repeat regions of the SARS virus S2 protein
Q40293043Subunit stoichiometry of human immunodeficiency virus type 1 envelope glycoprotein trimers during virus entry into host cells
Q40165402Surface density of the Hendra G protein modulates Hendra F protein-promoted membrane fusion: role for Hendra G protein trafficking and degradation
Q42638352TR1.3 viral pathogenesis and syncytium formation are linked to Env-Gag cooperation
Q37175177Targeted strategies for henipavirus therapeutics
Q43181323The anti-HIV actions of 7- and 10-substituted camptothecins.
Q34545634The avian coronavirus infectious bronchitis virus undergoes direct low-pH-dependent fusion activation during entry into host cells
Q37159933The biophysical function of pulmonary surfactant
Q36585513The conserved plant sterility gene HAP2 functions after attachment of fusogenic membranes in Chlamydomonas and Plasmodium gametes
Q34787116The final conformation of the complete ectodomain of the HA2 subunit of influenza hemagglutinin can by itself drive low pH-dependent fusion
Q37027166The growth and potential of human antiviral monoclonal antibody therapeutics.
Q40179783The hr1 and fusion peptide regions of the subgroup B avian sarcoma and leukosis virus envelope glycoprotein influence low pH-dependent membrane fusion
Q33614501The pH of activation of the hemagglutinin protein regulates H5N1 influenza virus pathogenicity and transmissibility in ducks.
Q33930439The product of the vaccinia virus L5R gene is a fourth membrane protein encoded by all poxviruses that is required for cell entry and cell-cell fusion
Q41345703The role of the N-terminal segment of CCR5 in HIV-1 Env-mediated membrane fusion and the mechanism of virus adaptation to CCR5 lacking this segment
Q36469974The structural basis of paramyxovirus invasion
Q27655400The structure of a cytolytic alpha-helical toxin pore reveals its assembly mechanism
Q34742453The transmembrane domain sequence affects the structure and function of the Newcastle disease virus fusion protein
Q35784690Thiol/disulfide exchange is required for membrane fusion directed by the Newcastle disease virus fusion protein
Q24538796Transmembrane peptides stabilize inverted cubic phases in a biphasic length-dependent manner: implications for protein-induced membrane fusion
Q41080258Transmembrane proteins are not required for early stages of nuclear envelope assembly
Q35947676Two distinct low-pH steps promote entry of vaccinia virus
Q37714227Use of herpes simplex virus and pseudorabies virus chimeric glycoprotein D molecules to identify regions critical for membrane fusion
Q33908798Vaccinia virus A21 virion membrane protein is required for cell entry and fusion
Q35101454Vaccinia virus G9 protein is an essential component of the poxvirus entry-fusion complex
Q35024254Vaccinia virus entry into cells via a low-pH-dependent endosomal pathway
Q37238558Vaccinia virus strain differences in cell attachment and entry
Q24631787Viral and developmental cell fusion mechanisms: conservation and divergence
Q37941707Viral infection: Moving through complex and dynamic cell-membrane structures.
Q41812409Virosome presents multimodel cancer therapy without viral replication
Q29619349Virus entry: open sesame
Q29620769Virus membrane-fusion proteins: more than one way to make a hairpin
Q28487427Virus neutralisation: new insights from kinetic neutralisation curves
Q37681125Viruses as vesicular carriers of the viral genome: a functional module perspective.
Q63739867Zika virus: mapping and reprogramming the entry
Q40410440pH-induced activation of arenavirus membrane fusion is antagonized by small-molecule inhibitors

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