Cyclooxygenase-2 enhances alpha2beta1 integrin expression and cell migration via EP1 dependent signaling pathway in human chondrosarcoma cells

scientific article

Cyclooxygenase-2 enhances alpha2beta1 integrin expression and cell migration via EP1 dependent signaling pathway in human chondrosarcoma cells is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1032591492
P356DOI10.1186/1476-4598-9-43
P932PMC publication ID2837621
P698PubMed publication ID20178602
P5875ResearchGate publication ID41547681

P2093author name stringChih-Hsin Tang
Chin-Jung Hsu
Hsien-Te Chen
Chih-Shiang Chang
Chih-Yi Chen
Chun-Yin Huang
Ju-Fang Liu
Long-Bin Jeng
Wei-Hung Yang
Yi-Chin Fong
P2860cites workCyclooxygenase-2 expression is up-regulated in human pancreatic cancerQ74592734
Increased expression of cyclooxygenase 2 occurs frequently in human lung cancers, specifically in adenocarcinomasQ77220353
Intratumoral lymphatic vessels: a case of mistaken identity or malfunction?Q77794181
Ultrasound induces cyclooxygenase-2 expression through integrin, integrin-linked kinase, Akt, NF-kappaB and p300 pathway in human chondrocytesQ80782862
Absence of a correlation between the presence of a single nucleotide polymorphism in the matrix metalloproteinase 1 promoter and outcome in patients of chondrosarcomaQ80980471
The role of prostaglandin E receptor subtypes (EP1, EP2, EP3, and EP4) in bone resorption: an analysis using specific agonists for the respective EPsQ28375076
Prostaglandin E2 stimulates fibronectin expression through EP1 receptor, phospholipase C, protein kinase Calpha, and c-Src pathway in primary cultured rat osteoblastsQ28569432
Expression of the prostaglandin E(2) (PGE(2)) receptor subtype EP(4) and its regulation by PGE(2) in osteoblastic cell lines and adult rat bone tissueQ28572536
Cyclooxygenases: structural, cellular, and molecular biologyQ29616510
Cancer metastasis: building a frameworkQ29616783
Cloning and expression of a cDNA for mouse prostaglandin E receptor EP3 subtypeQ31169232
Integrin structureQ33915456
Cyclooxygenase-2: a therapeutic targetQ34111944
Divergent effects of new cyclooxygenase inhibitors on gastric ulcer healing: Shifting the angiogenic balance.Q34192374
Cyclooxygenase-2 induces EP1- and HER-2/Neu-dependent vascular endothelial growth factor-C up-regulation: a novel mechanism of lymphangiogenesis in lung adenocarcinomaQ34292697
Autocrine/paracrine prostaglandin E2 production by non-small cell lung cancer cells regulates matrix metalloproteinase-2 and CD44 in cyclooxygenase-2-dependent invasionQ34646962
Off-target effects by siRNA can induce toxic phenotypeQ34703017
Distinct functions of COX-1 and COX-2.Q34997943
Cyclooxygenases: new forms, new inhibitors, and lessons from the clinicQ35760394
Targeting prostaglandin E EP receptors to inhibit metastasisQ36626270
The mouse prostaglandin E receptor EP2 subtype: cloning, expression, and northern blot analysisQ36681241
Cloning and expression of cDNA for a mouse EP1 subtype of prostaglandin E receptorQ36697107
Involvement of AdipoR receptor in adiponectin-induced motility and alpha2beta1 integrin upregulation in human chondrosarcoma cellsQ39834275
Cyr61 increases migration and MMP-13 expression via alphavbeta3 integrin, FAK, ERK and AP-1-dependent pathway in human chondrosarcoma cellsQ39898176
Vanillin inhibits matrix metalloproteinase-9 expression through down-regulation of nuclear factor-kappaB signaling pathway in human hepatocellular carcinoma cellsQ39932437
Stromal cell-derived factor-1 increase alphavbeta3 integrin expression and invasion in human chondrosarcoma cells.Q39936366
Involvement of matrix metalloproteinase-9 in stromal cell-derived factor-1/CXCR4 pathway of lung cancer metastasisQ40071923
Elevated expression of Cyr61 enhances peritoneal dissemination of gastric cancer cells through integrin alpha2beta1.Q40074224
Role of the beta1-integrin subunit in the adhesion, extravasation and migration of T24 human bladder carcinoma cellsQ40387485
Hypersialylation of beta1 integrins, observed in colon adenocarcinoma, may contribute to cancer progression by up-regulating cell motilityQ40414546
RNAi mediated MMP-1 silencing inhibits human chondrosarcoma invasionQ40415092
Cyclooxygenase inhibitors retard murine mammary tumor progression by reducing tumor cell migration, invasiveness and angiogenesisQ40789590
Multi-faceted analyses of a highly metastatic human lung cancer cell line NCI-H460-LNM35 suggest mimicry of inflammatory cells in metastasis.Q40791025
Tumour necrosis factor-alpha provokes upregulation of alpha2beta1 and alpha5beta1 integrins, and cell migration in OST osteosarcoma cellsQ40810266
Altered expression and function of beta1 integrins in a highly metastatic human lung adenocarcinoma cell line.Q40842418
Akt stimulates the transactivation potential of the RelA/p65 Subunit of NF-kappa B through utilization of the Ikappa B kinase and activation of the mitogen-activated protein kinase p38.Q42830960
Cyclooxygenase-2 overexpression reduces apoptotic susceptibility by inhibiting the cytochrome c-dependent apoptotic pathway in human colon cancer cells.Q44203835
Requirement of Gbetagamma and c-Src in D2 dopamine receptor-mediated nuclear factor-kappaB activationQ44517638
Integrin chains beta1 and alphav as prognostic factors in human metastatic melanoma.Q44848602
Oxidized phospholipids increase interleukin 8 (IL-8) synthesis by activation of the c-src/signal transducers and activators of transcription (STAT)3 pathwayQ44895871
Leptin enhances cell migration in human chondrosarcoma cells through OBRl leptin receptorQ46147836
Increased beta1 integrin is associated with decreased survival in invasive breast cancerQ46447755
Expression of cyclooxygenase-1 and -2 in human colorectal cancerQ53461597
Chemotherapy and P-glycoprotein expression in chondrosarcomaQ60146944
Thrombin signal transduction mechanisms in rat vascular smooth muscle cells. Calcium and protein kinase C-dependent and -independent pathwaysQ67672649
Prognostic value of beta1-integrin (=CD29) in serous adenocarcinomas of the ovaryQ74361860
Expression of cyclooxygenase-1 and cyclooxygenase-2 in human breast cancerQ74376052
P407language of work or nameEnglishQ1860
P921main subjectcell migrationQ189092
chondrosarcomaQ1076087
P304page(s)43
P577publication date2010-02-23
P1433published inMolecular CancerQ15724585
P1476titleCyclooxygenase-2 enhances alpha2beta1 integrin expression and cell migration via EP1 dependent signaling pathway in human chondrosarcoma cells
P478volume9

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cites work (P2860)
Q35793821Amphiregulin enhances alpha6beta1 integrin expression and cell motility in human chondrosarcoma cells through Ras/Raf/MEK/ERK/AP-1 pathway.
Q36562200Amphiregulin enhances intercellular adhesion molecule-1 expression and promotes tumor metastasis in human osteosarcoma
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Q39587555CCN3 increases cell motility and MMP-13 expression in human chondrosarcoma through integrin-dependent pathway
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Q38098398COX-2 in cancer: Gordian knot or Achilles heel?
Q51141555Correlations of IGF-1R and COX-2 Expressions with Ras and BRAF Genetic Mutations, Clinicopathological Features and Prognosis of Colorectal Cancer Patients.
Q37274028Cyclooxygenase-2 induced β1-integrin expression in NSCLC and promoted cell invasion via the EP1/MAPK/E2F-1/FoxC2 signal pathway
Q34224752Cyclooxygenases and lipoxygenases in cancer
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Q37734894Prostaglandin E2 stimulates β1-integrin expression in hepatocellular carcinoma through the EP1 receptor/PKC/NF-κB pathway
Q33567396Prostanoid EP1 receptor as the target of (-)-epigallocatechin-3-gallate in suppressing hepatocellular carcinoma cells in vitro
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Q36312486TSC2 modulates cell adhesion and migration via integrin-α1β1
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