Stepwise metabolic adaption from pure metabolization to balanced anaerobic growth on xylose explored for recombinant Saccharomyces cerevisiae

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Stepwise metabolic adaption from pure metabolization to balanced anaerobic growth on xylose explored for recombinant Saccharomyces cerevisiae is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1027226171
P356DOI10.1186/1475-2859-13-37
P932PMC publication ID4007572
P698PubMed publication ID24606998
P5875ResearchGate publication ID260644509

P50authorMario KlimacekQ123474875
Stefan KrahulecQ123474878
Bernd NidetzkyQ42118706
P2093author name stringVera Novy
Karin Longus
Elisabeth Kirl
P2860cites workComparison of the xylose reductase-xylitol dehydrogenase and the xylose isomerase pathways for xylose fermentation by recombinant Saccharomyces cerevisiaeQ21246025
Limitations in Xylose-FermentingSaccharomyces cerevisiae, Made Evident through Comprehensive Metabolite Profiling and Thermodynamic AnalysisQ30475607
Co-fermentation of hexose and pentose sugars in a spent sulfite liquor matrix with genetically modified Saccharomyces cerevisiaeQ85892450
An efficient xylose-fermenting recombinant Saccharomyces cerevisiae strain obtained through adaptive evolution and its global transcription profileQ87423427
Fermentation of mixed glucose-xylose substrates by engineered strains of Saccharomyces cerevisiae: role of the coenzyme specificity of xylose reductase, and effect of glucose on xylose utilizationQ30482447
Altering the coenzyme preference of xylose reductase to favor utilization of NADH enhances ethanol yield from xylose in a metabolically engineered strain of Saccharomyces cerevisiaeQ30494926
Structural and functional properties of a yeast xylitol dehydrogenase, a Zn2+-containing metalloenzyme similar to medium-chain sorbitol dehydrogenasesQ31979159
Physiological and genome-wide transcriptional responses of Saccharomyces cerevisiae to high carbon dioxide concentrations.Q33433079
Increased Ethanol Productivity in Xylose-Utilizing Saccharomyces cerevisiae via a Randomly Mutagenized Xylose ReductaseQ33708719
Stoichiometry and compartmentation of NADH metabolism in Saccharomyces cerevisiaeQ33930915
Evolutionary engineering of industrially important microbial phenotypesQ34509849
Engineering yeasts for xylose metabolismQ36483389
Growth and fermentation of D-xylose by Saccharomyces cerevisiae expressing a novel D-xylose isomerase originating from the bacterium Prevotella ruminicola TC2-24.Q36905765
Metabolic engineering for pentose utilization in Saccharomyces cerevisiaeQ36936778
Development of efficient xylose fermentation in Saccharomyces cerevisiae: xylose isomerase as a key component.Q36936782
Ethanol production from xylose in engineered Saccharomyces cerevisiae strains: current state and perspectives.Q37538569
Stress-related challenges in pentose fermentation to ethanol by the yeast Saccharomyces cerevisiae.Q37838374
Engineering Saccharomyces cerevisiae for efficient anaerobic xylose fermentation: reflections and perspectivesQ37965464
Strain engineering of Saccharomyces cerevisiae for enhanced xylose metabolism.Q38092531
Adaptive laboratory evolution -- principles and applications for biotechnologyQ38118393
Gpd1 and Gpd2 fine-tuning for sustainable reduction of glycerol formation in Saccharomyces cerevisiae.Q38283443
Evolutionary engineering of Saccharomyces cerevisiae for anaerobic growth on xyloseQ39751889
Molecular basis for anaerobic growth of Saccharomyces cerevisiae on xylose, investigated by global gene expression and metabolic flux analysisQ40744256
Development of a D-xylose fermenting and inhibitor tolerant industrial Saccharomyces cerevisiae strain with high performance in lignocellulose hydrolysates using metabolic and evolutionary engineering.Q41394061
Analysis and prediction of the physiological effects of altered coenzyme specificity in xylose reductase and xylitol dehydrogenase during xylose fermentation by Saccharomyces cerevisiaeQ41824569
The coenzyme specificity of Candida tenuis xylose reductase (AKR2B5) explored by site-directed mutagenesis and X-ray crystallographyQ41954443
Increased expression of the oxidative pentose phosphate pathway and gluconeogenesis in anaerobically growing xylose-utilizing Saccharomyces cerevisiaeQ42035332
Quantitative physiology of Saccharomyces cerevisiae at near-zero specific growth rates.Q42545882
Metabolic engineering of Saccharomyces cerevisiae for conversion of D-glucose to xylitol and other five-carbon sugars and sugar alcoholsQ42621523
Evolutionary adaptation of recombinant shochu yeast for improved xylose utilization.Q43029013
Furfural, 5-hydroxymethyl furfural, and acetoin act as external electron acceptors during anaerobic fermentation of xylose in recombinant Saccharomyces cerevisiaeQ43900067
Characterization of recombinant xylitol dehydrogenase from Galactocandida mastotermitis expressed in Escherichia coliQ44326982
Minimal metabolic engineering of Saccharomyces cerevisiae for efficient anaerobic xylose fermentation: a proof of principleQ44812140
Fermentation performance of engineered and evolved xylose-fermenting Saccharomyces cerevisiae strains.Q44947501
Energetics of Saccharomyces cerevisiae in anaerobic glucose-limited chemostat culturesQ45227049
Metabolic engineering of a xylose-isomerase-expressing Saccharomyces cerevisiae strain for rapid anaerobic xylose fermentationQ45251239
Engineering of a matched pair of xylose reductase and xylitol dehydrogenase for xylose fermentation by Saccharomyces cerevisiae.Q46006247
Evolutionary engineering of mixed-sugar utilization by a xylose-fermenting Saccharomyces cerevisiae strainQ46540264
The expression of a Pichia stipitis xylose reductase mutant with higher K(M) for NADPH increases ethanol production from xylose in recombinant Saccharomyces cerevisiaeQ46863962
Xylose fermentation by yeasts. 5. Use of ATP balances for modeling oxygen-limited growth and fermentation of yeast Pichia stipitis with xylose as carbon source.Q52524224
Noncovalent enzyme-substrate interactions in the catalytic mechanism of yeast aldose reductase.Q54124450
Xylose isomerase overexpression along with engineering of the pentose phosphate pathway and evolutionary engineering enable rapid xylose utilization and ethanol production by Saccharomyces cerevisiae.Q54488420
Stoichiometry and compartmentation of NADH metabolism inSaccharomyces cerevisiaeQ56267572
Physiology of Saccharomyces cerevisiae in anaerobic glucose-limited chemostat culturesQ68094386
Improvement of xylose fermentation in respiratory-deficient xylose-fermenting Saccharomyces cerevisiaeQ83009000
Saccharomyces cerevisiae engineered for xylose metabolism requires gluconeogenesis and the oxidative branch of the pentose phosphate pathway for aerobic xylose assimilationQ84646594
P433issue1
P921main subjectSaccharomyces cerevisiaeQ719725
P304page(s)37
P577publication date2014-03-08
P1433published inMicrobial Cell FactoriesQ15766995
P1476titleStepwise metabolic adaption from pure metabolization to balanced anaerobic growth on xylose explored for recombinant Saccharomyces cerevisiae
P478volume13

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cites work (P2860)
Q42365699Anaerobic poly-3-D-hydroxybutyrate production from xylose in recombinant Saccharomyces cerevisiae using a NADH-dependent acetoacetyl-CoA reductase.
Q28542984Engineering and two-stage evolution of a lignocellulosic hydrolysate-tolerant Saccharomyces cerevisiae strain for anaerobic fermentation of xylose from AFEX pretreated corn stover
Q35440018From wheat straw to bioethanol: integrative analysis of a separate hydrolysis and co-fermentation process with implemented enzyme production
Q52593419L-Lactic acid production from glucose and xylose with engineered strains of Saccharomyces cerevisiae: aeration and carbon source influence yields and productivities.
Q41611333Saccharomyces cerevisiae strain comparison in glucose-xylose fermentations on defined substrates and in high-gravity SSCF: convergence in strain performance despite differences in genetic and evolutionary engineering history.
Q41154349Sustaining fermentation in high-gravity ethanol production by feeding yeast to a temperature-profiled multifeed simultaneous saccharification and co-fermentation of wheat straw
Q92544990The emergence of adaptive laboratory evolution as an efficient tool for biological discovery and industrial biotechnology
Q50783792Toward "homolactic" fermentation of glucose and xylose by engineered Saccharomyces cerevisiae harboring a kinetically efficient l-lactate dehydrogenase within pdc1-pdc5 deletion background.
Q26765467Xylose Fermentation by Saccharomyces cerevisiae: Challenges and Prospects
Q38293358Xylose fermentation as a challenge for commercialization of lignocellulosic fuels and chemicals.

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