| P50 | author | Bradley W Kesser | Q70426433 |
| P2093 | author name string | Jeffrey R Holt | |
| | George T Hashisaki | |
| P2860 | cites work | KCNQ4, a novel potassium channel expressed in sensory outer hair cells, is mutated in dominant deafness | Q22008780 |
| | A defect in harmonin, a PDZ domain-containing protein expressed in the inner ear sensory hair cells, underlies Usher syndrome type 1C | Q24290185 |
| | Usher syndrome type I G (USH1G) is caused by mutations in the gene encoding SANS, a protein that associates with the USH1C protein, harmonin | Q24294773 |
| | PCDH15 is expressed in the neurosensory epithelium of the eye and ear and mutant alleles are responsible for both USH1F and DFNB23 | Q24298183 |
| | Defective myosin VIIA gene responsible for Usher syndrome type 1B | Q24314638 |
| | A novel mutation in the potassium channel gene KVLQT1 causes the Jervell and Lange-Nielsen cardioauditory syndrome | Q24318498 |
| | Mutations of MYO6 are associated with recessive deafness, DFNB37 | Q24532041 |
| | Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of the novel cadherin-like gene CDH23 | Q24535604 |
| | MYO6, the human homologue of the gene responsible for deafness in Snell's waltzer mice, is mutated in autosomal dominant nonsyndromic hearing loss | Q24535864 |
| | A simplified system for generating recombinant adenoviruses | Q24682328 |
| | Math1 gene transfer generates new cochlear hair cells in mature guinea pigs in vivo | Q28178896 |
| | KCNE1 mutations cause jervell and Lange-Nielsen syndrome | Q28253362 |
| | Shaker-1 mutations reveal roles for myosin VIIA in both development and function of cochlear hair cells | Q28509764 |
| | Math1: an essential gene for the generation of inner ear hair cells | Q28513764 |
| | Mutations in Cdh23, encoding a new type of cadherin, cause stereocilia disorganization in waltzer, the mouse model for Usher syndrome type 1D | Q28589238 |
| | The mouse Ames waltzer hearing-loss mutant is caused by mutation of Pcdh15, a novel protocadherin gene | Q28589565 |
| | TRPA1 is a candidate for the mechanosensitive transduction channel of vertebrate hair cells | Q28591781 |
| | Complementary roles of BDNF and NT-3 in vestibular and auditory development | Q28594015 |
| | Mice with altered KCNQ4 K+ channels implicate sensory outer hair cells in human progressive deafness | Q28594332 |
| | Viral-mediated gene transfer to study the molecular physiology of the Mammalian inner ear. | Q30309437 |
| | An in vitro model system to study gene therapy in the human inner ear. | Q30438620 |
| | Dominant-negative inhibition of M-like potassium conductances in hair cells of the mouse inner ear | Q30440196 |
| | Spiral ganglion neurons are protected from degeneration by GDNF gene therapy. | Q30473538 |
| | Morphology of auditory hair cells in guinea pig cochlea after transgene expression | Q33200503 |
| | Structural recovery from sound and aminoglycoside damage in the avian cochlea. | Q33749308 |
| | Vestibular hair cell regeneration and restoration of balance function induced by math1 gene transfer | Q46713382 |
| | Cochlear gene transfer: round window versus cochleostomy inoculation | Q48097614 |
| | NT-3 and/or BDNF therapy prevents loss of auditory neurons following loss of hair cells | Q49052948 |
| | Glutathione limits noise-induced hearing loss. | Q50495238 |
| | Cracking the auditory genetic code: nonsyndromic hereditary hearing impairment. | Q50502591 |
| | Hair cells and supporting cells share a common progenitor in the avian inner ear. | Q50504230 |
| | Adenoviral-mediated gene transfer into guinea pig cochlear cells in vivo. | Q50515400 |
| | New hair cells arise from supporting cell conversion in the acoustically damaged chick inner ear. | Q50515888 |
| | Transgene expression in mature guinea pig cochlear cells in vitro | Q64378275 |
| | Functional expression of exogenous proteins in mammalian sensory hair cells infected with adenoviral vectors | Q64381584 |
| | Transfection of neonatal rat cochlear cells in vitro with an adenovirus vector | Q64382380 |
| | Cochlear gene therapy | Q73818064 |
| | A novel vestibular approach for gene transfer into the inner ear | Q78604396 |
| | Progress with retroviral gene vectors | Q33920752 |
| | Auditory hair cell replacement and hearing improvement by Atoh1 gene therapy in deaf mammals | Q34394494 |
| | Association of unconventional myosin MYO15 mutations with human nonsyndromic deafness DFNB3. | Q34469642 |
| | HIV-1-derived lentiviral vectors | Q34561994 |
| | Neuronal survival and cell death signaling pathways. | Q35063052 |
| | KCNQ4, a K+ channel mutated in a form of dominant deafness, is expressed in the inner ear and the central auditory pathway. | Q35682356 |
| | Utilization of adenovirus vectors for multiple gene transfer applications | Q35762017 |
| | Drug delivery to the inner ear using gene therapy. | Q35912971 |
| | Hearing and hair cells are protected by adenoviral gene therapy with TGF-β1 and GDNF | Q40650824 |
| | Glial cell line-derived neurotrophic factor and chronic electrical stimulation prevent VIII cranial nerve degeneration following denervation | Q40688618 |
| | Gene expression in the mammalian cochlea: a study of multiple vector systems. | Q40708362 |
| | A surgical approach appropriate for targeted cochlear gene therapy in the mouse | Q40734130 |
| | Differential protective effects of neurotrophins in the attenuation of noise-induced hair cell loss | Q40865835 |
| | Effect of transgenic GDNF expression on gentamicin-induced cochlear and vestibular toxicity | Q40871245 |
| | Green fluorescent protein as a reporter for gene transfer studies in the cochlea | Q40871576 |
| | Glial cell line-derived neurotrophic factor. Potential for otoprotection | Q40875441 |
| | Glial cell line-derived neurotrophic factor has a dose dependent influence on noise-induced hearing loss in the guinea pig cochlea | Q40889342 |
| | Development of in vivo gene therapy for hearing disorders: introduction of adeno-associated virus into the cochlea of the guinea pig. | Q40934948 |
| | Development of retroviral vectors as safe, targeted gene delivery systems | Q40944251 |
| | Viral vectors in gene therapy | Q40945246 |
| | Attenuation of cochlear damage from noise trauma by an iron chelator, a free radical scavenger and glial cell line-derived neurotrophic factor in vivo | Q40983153 |
| | Guinea pig auditory neurons are protected by glial cell line-derived growth factor from degeneration after noise trauma | Q40993628 |
| | GDNF protects the cochlea against noise damage | Q41019032 |
| | Defective HSV-1 vector expressing BDNF in auditory ganglia elicits neurite outgrowth: model for treatment of neuron loss following cochlear degeneration | Q41237702 |
| | Cationic liposome mediated transgene expression in the guinea pig cochlea | Q41614363 |
| | The protective effect of brain-derived neurotrophic factor after gentamicin ototoxicity. | Q41666663 |
| | Transgene expression in the guinea pig cochlea mediated by a lentivirus-derived gene transfer vector | Q41685193 |
| | Overexpression of Math1 induces robust production of extra hair cells in postnatal rat inner ears | Q41736617 |
| | Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brain | Q42280576 |
| | Hearing preservation after inner ear gene therapy: the effect of vector and surgical approach. | Q42451504 |
| | Correction of deafness in shaker-2 mice by an unconventional myosin in a BAC transgene. | Q42455765 |
| | Transgene correction maintains normal cochlear structure and function in 6-month-old Myo15a mutant mice | Q42492876 |
| | In vivo adenoviral transduction of the neonatal rat cochlea and middle ear. | Q42497484 |
| | In vitro and in vivo assessment of the ability of adeno-associated virus-brain-derived neurotrophic factor to enhance spiral ganglion cell survival following ototoxic insult | Q42524699 |
| | Interactions of mammalian cells with lipid dispersions containing novel metabolizable cationic amphiphiles | Q42832960 |
| | Antioxidant gene therapy can protect hearing and hair cells from ototoxicity | Q43169212 |
| | Robust generation of new hair cells in the mature mammalian inner ear by adenoviral expression of Hath1. | Q44042846 |
| | Long-term in vivo cochlear transgene expression mediated by recombinant adeno-associated virus | Q44136141 |
| | A modified adenovirus can transfect cochlear hair cells in vivo without compromising cochlear function | Q44441757 |
| | Ebselen attenuates cochlear damage caused by acoustic trauma | Q44509557 |
| | Gene transfer into supporting cells of the organ of Corti | Q44835605 |
| | The functional and structural outcome of inner ear gene transfer via the vestibular and cochlear fluids in mice | Q45071652 |
| | A novel bovine virus efficiently transduces inner ear neuroepithelial cells | Q45457216 |
| | Adeno-associated virus-mediated gene transfer to hair cells and support cells of the murine cochlea | Q45457280 |
| | Cochlear function and transgene expression in the guinea pig cochlea, using adenovirus- and adeno-associated virus-directed gene transfer. | Q45737477 |
| | Gene transfer into the mammalian inner ear using HSV-1 and vaccinia virus vectors | Q45747744 |
| | Expression of adeno-associated virus integrated transgene within the mammalian vestibular organs. | Q45756022 |
| | The effect of cochleostomy and intracochlear infusion on auditory brain stem response threshold in the guinea pig. | Q45855751 |
| | Inner ear transgene expression after adenoviral vector inoculation in the endolymphatic sac. | Q45857676 |
| | Transduction of the contralateral ear after adenovirus-mediated cochlear gene transfer | Q45865689 |
| | Adenovirus-mediated expression of brain-derived neurotrophic factor protects spiral ganglion neurons from ototoxic damage | Q45874526 |
| | Novel method for homogeneous gene transfer to the inner ear. | Q45876825 |
| | Viral-mediated gene transfer in the cochlea | Q45883103 |
| | Brain-derived neurotrophic factor gene therapy prevents spiral ganglion degeneration after hair cell loss | Q45888449 |
| | Cochlear microinjection and its effects upon auditory function in the guinea pig. | Q46100531 |
| | Ebselen prevents noise-induced excitotoxicity and temporary threshold shift | Q46464961 |
| | Cochlear gene delivery through an intact round window membrane in mouse | Q46630707 |
| P433 | issue | 5 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | gene therapy | Q213901 |
| P304 | page(s) | 821-831 | |
| P577 | publication date | 2008-05-01 | |
| P1433 | published in | The Laryngoscope | Q15755068 |
| P1476 | title | Gene transfer in human vestibular epithelia and the prospects for inner ear gene therapy | |
| P478 | volume | 118 | |