Pathophysiology of sleep apnea

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Pathophysiology of sleep apnea is …
instance of (P31):
review articleQ7318358
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P356DOI10.1152/PHYSREV.00043.2008
P8608Fatcat IDrelease_l7ox3i7ldjdujl7bbjkwvgfx3y
P932PMC publication ID3970937
P698PubMed publication ID20086074
P5875ResearchGate publication ID41088175

P50authorJerome DempseyQ29653442
P2093author name stringBarbara J Morgan
Christopher P O'Donnell
Sigrid C Veasey
P2860cites workChildhood obstructive sleep apnea associates with neuropsychological deficits and neuronal brain injuryQ21144702
Short sleep duration is associated with reduced leptin, elevated ghrelin, and increased body mass indexQ21144740
Impact of sleep debt on metabolic and endocrine functionQ23731787
Blood pressure associated with sleep-disordered breathing in a population sample of childrenQ24605368
Angiogenesis in cancer and other diseasesQ27861015
Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of IkkbetaQ28188643
DISTRIBUTION OF BLOOD FLOW IN ISOLATED LUNG; RELATION TO VASCULAR AND ALVEOLAR PRESSURESQ28198229
Sleep-disordered breathing in patients with symptomatic heart failure: a contemporary study of prevalence in and characteristics of 700 patientsQ28267419
Modulation of hypoglossal motoneuron excitability by NK1 receptor activation in neonatal mice in vitroQ28344027
Cerebral metabolic impairment in patients with obstructive sleep apnoea: an independent association of obstructive sleep apnoea with white matter changeQ28346304
Augmented endothelin vasoconstriction in intermittent hypoxia-induced hypertensionQ28570889
Endoplasmic reticulum stress inhibition protects against excitotoxic neuronal injury in the rat brainQ28572076
Regulation of the angiotensin-converting enzyme activity by a time-course hypoxia in the carotid bodyQ28577913
Differential effects of chronic hypoxia and intermittent hypocapnic and eucapnic hypoxia on pulmonary vasoreactivityQ28578154
Effect of deficiency in SREBP cleavage-activating protein on lipid metabolism during intermittent hypoxiaQ28588503
The occurrence of sleep-disordered breathing among middle-aged adultsQ29547889
Brief communication: Sleep curtailment in healthy young men is associated with decreased leptin levels, elevated ghrelin levels, and increased hunger and appetiteQ29615447
Long-term cardiovascular outcomes in men with obstructive sleep apnoea-hypopnoea with or without treatment with continuous positive airway pressure: an observational studyQ29615583
Leptin and the regulation of body weight in mammalsQ29615976
Prospective study of the association between sleep-disordered breathing and hypertensionQ29620492
Continuous positive airway pressure improves vascular function in obstructive sleep apnoea/hypopnoea syndrome: a randomised controlled trialQ46662974
Predictors of blood pressure fall with continuous positive airway pressure (CPAP) treatment of obstructive sleep apnoea (OSA).Q46664744
Effects of continuous positive airway pressure versus supplemental oxygen on 24-hour ambulatory blood pressureQ46684398
Central sleep apnea in stable methadone maintenance treatment patientsQ46703250
Role of gp91phox-containing NADPH oxidase in left ventricular remodeling induced by intermittent hypoxic stressQ46713753
Eif-2a protects brainstem motoneurons in a murine model of sleep apneaQ46729669
Long-term improvement of insulin sensitivity during CPAP therapy in the obstructive sleep apnoea syndrome.Q46732694
Electrocardiographically indicated cardiovascular disease in sleep-disordered breathingQ46774096
Continuous positive airway pressure for central sleep apnea and heart failureQ46799634
Opiate slowing of feline respiratory rhythm and effects on putative medullary phase-regulating neuronsQ46801049
Frequency of distribution of leptin receptor gene polymorphism in obstructive sleep apnea patients.Q46801934
Positron emission tomography findings in obstructive sleep apnea patients with residual sleepiness treated with continuous positive airway pressure.Q46802024
The severity of oxygen desaturation is predictive of carotid wall thickening and plaque occurrence.Q46817068
Serotoninergic receptors in the anteroventral preoptic region modulate the hypoxic ventilatory responseQ46822411
Activation and desensitization of neuronal nicotinic receptors modulate glutamatergic transmission on neonatal rat hypoglossal motoneuronsQ46832677
Chronic intermittent hypoxia alters NE reactivity and mechanics of skeletal muscle resistance arteriesQ46853084
Noradrenergic, serotonergic and GABAergic antagonists injected together into the XII nucleus abolish the REM sleep-like depression of hypoglossal motoneuronal activityQ46858431
Pulmonary hypertension in obstructive sleep apnoea: effects of continuous positive airway pressure: a randomized, controlled cross-over studyQ46960378
Continuous positive airway pressure improves daytime baroreflex sensitivity and nitric oxide production in patients with moderate to severe obstructive sleep apnea syndromeQ46965619
Atomoxetine improves sleepiness and global severity of illness but not the respiratory disturbance index in mild to moderate obstructive sleep apnea with sleepinessQ46977506
Pharyngeal size and shape during wakefulness and sleep in patients with obstructive sleep apnoeaQ47172024
Pharyngeal size in snorers, nonsnorers, and patients with obstructive sleep apneaQ47203231
Hypoxic pressor response, cardiac size, and natriuretic peptides are modified by long-term intermittent hypoxiaQ47251020
Recent weight gain in patients with newly diagnosed obstructive sleep apneaQ47257483
The correlation between adiposity and adiponectin, tumor necrosis factor alpha, interleukin-6 and high sensitivity C-reactive protein levels. Is adipocyte size associated with inflammation in adults?Q47288086
Relationship between adipocyte size and adipokine expression and secretionQ47310274
Excess weight and sleep-disordered breathingQ47368959
The association of left atrial size and occurrence of atrial fibrillation: a prospective cohort study from the Canadian Registry of Atrial FibrillationQ47405338
Effect of weight loss on upper airway collapsibility in obstructive sleep apneaQ47425576
Hypoxia-mediated prolonged elevation of sympathetic nerve activity after periods of intermittent hypoxic apneaQ47446409
Upper airway muscle inflammation and denervation changes in obstructive sleep apneaQ47582296
Ontogeny of postnatal hyoid and larynx descent in humansQ47643615
Continuous positive airway pressure does not reduce blood pressure in nonsleepy hypertensive OSA patientsQ47644015
Effects of nocturnal oxygen therapy on outcome measures in patients with chronic heart failure and cheyne-stokes respirationQ47663430
Mathematical models of periodic breathing and their usefulness in understanding cardiovascular and respiratory disordersQ47692638
The ontogeny of cranial base angulation in humans and chimpanzees and its implications for reconstructing pharyngeal dimensionsQ47719815
Influence of arterial O2 on the susceptibility to posthyperventilation apnea during sleepQ47723312
Surface tension of upper airway mucosal lining liquid in obstructive sleep apnea/hypopnea syndromeQ47725470
Diurnal and obstructive sleep apnea influences on arterial stiffness and central blood pressure in men.Q47725503
Response time and sensitivity of the ventilatory response to CO2 in unanesthetized intact dogs: central vs. peripheral chemoreceptorsQ47726910
Obstructive sleep apnea: Plasma endothelin-1 precursor but not endothelin-1 levels are elevated and decline with nasal continuous positive airway pressureQ47742694
Ventilation is unstable during drowsiness before sleep onsetQ47762439
Acute and chronic cardiovascular effects of intermittent hypoxia in C57BL/6J miceQ47767899
Cerebrovascular response to carbon dioxide in patients with congestive heart failureQ47794875
Down regulation of Kv3.4 channels by chronic hypoxia increases acute oxygen sensitivity in rabbit carotid body.Q47797805
Platelet activation, epinephrine, and blood pressure in obstructive sleep apnea syndromeQ47801435
Craniofacial morphology, head posture, and nasal respiratory resistance in obstructive sleep apnoea: an inter-ethnic comparisonQ47839551
Cerebral structural changes in severe obstructive sleep apneaQ47852334
Functional imaging of working memory in obstructive sleep-disordered breathingQ47858547
Effect of treatment by nasal CPAP on cardiopulmonary exercise test in obstructive sleep apnea syndromeQ47869968
The Great Leap Forward: the anatomic basis for the acquisition of speech and obstructive sleep apneaQ35573209
Serotonin receptors: guardians of stable breathingQ35601739
Waking genioglossal electromyogram in sleep apnea patients versus normal controls (a neuromuscular compensatory mechanism).Q35602313
Mesopontine cholinergic projections to the hypoglossal motor nucleusQ35754242
Sympathetic neural mechanisms in obstructive sleep apnea.Q35764596
Oxidative stress in the systemic and cellular responses to intermittent hypoxiaQ35768167
Induction of sensory long-term facilitation in the carotid body by intermittent hypoxia: implications for recurrent apneasQ35812078
Sleep. 4: Sleepiness, cognitive function, and quality of life in obstructive sleep apnoea/hypopnoea syndromeQ35821094
The ventilatory responsiveness to CO(2) below eupnoea as a determinant of ventilatory stability in sleep.Q35850899
Cerebral ischemia and the unfolded protein responseQ35893250
Pontine cholinergic mechanisms and their impact on respiratory regulationQ35935553
Chronic opioid use is a risk factor for the development of central sleep apnea and ataxic breathingQ35995385
Association between metabolic syndrome and sleep-disordered breathing in adolescentsQ36013648
Long-term regulation of arterial blood pressure by hypothalamic nuclei: some critical questionsQ36107869
Cardiovascular alterations by chronic intermittent hypoxia: importance of carotid body chemoreflexes.Q36107883
NADPH oxidase-derived superoxide anion mediates angiotensin II-enhanced carotid body chemoreceptor sensitivity in heart failure rabbitsQ36114032
Load compensation and respiratory muscle function during sleepQ36145898
Reduced cerebral blood flow during wakefulness in obstructive sleep apnea-hypopnea syndromeQ36151492
Treatment of obstructive sleep apnoea leads to improved microvascular endothelial function in the systemic circulationQ36203132
Impact of obstructive apnea syndrome on upper airway respiratory musclesQ36212835
Cellular and molecular mechanisms associated with carotid body adaptations to chronic hypoxiaQ36214817
Influence of wakefulness on pharyngeal airway muscle activityQ36225941
Treatment for obstructive sleep apnoea: effect on peripheral nerve functionQ36226886
Role of the T cell in the genesis of angiotensin II induced hypertension and vascular dysfunctionQ36229028
Shared genetic risk factors for obstructive sleep apnea and obesity.Q36256296
Tumour necrosis factor-alpha (-308) gene polymorphism in obstructive sleep apnoea-hypopnoea syndrome.Q36276576
Recognition and management of complex sleep-disordered breathingQ36282909
Chronic intermittent hypoxia induces atherosclerosisQ36330538
Mechanical strain induces growth of vascular smooth muscle cells via autocrine action of PDGF.Q36383244
Respiratory control stability and upper airway collapsibility in men and women with obstructive sleep apneaQ36395020
The impact of anatomic manipulations on pharyngeal collapse: results from a computational model of the normal human upper airwayQ36405705
Genioglossal muscle response to CO2 stimulation during NREM sleepQ36405724
Appearance and transient expression of vasopressin and oxytocin receptors in the rat brainQ36419743
Prolonged expiratory phase in sleep apnea. A unifying hypothesisQ41485407
Changes in serotonin level in the hypoglossal nucleus region during carbachol-induced atonia.Q41662617
A neuromuscular mechanism maintaining extrathoracic airway patencyQ41686091
Acute effects of paroxetine on genioglossus activity in obstructive sleep apneaQ41711461
Cardiorespiratory consequences of sleep apnoea syndrome in patients with massive obesityQ41738835
Effects of graded reduction of brain blood flow on ventilation in unanesthetized goatsQ41738968
Sympathetic denervation blocks blood pressure elevation in episodic hypoxiaQ41980368
NFATc3 is required for intermittent hypoxia-induced hypertensionQ42410702
Medial and endothelial platelet-derived growth factor A chain expression is regulated by in vivo exposure to elevated flowQ42465571
Renin activity and blood pressure in response to chronic episodic hypoxiaQ42476427
Differential role of the paraventricular nucleus of the hypothalamus in modulating the sympathoexcitatory component of peripheral and central chemoreflexesQ42478844
Cellular mechanisms involved in rabbit carotid body excitation elicited by endothelin peptidesQ42489186
A putative flip-flop switch for control of REM sleepQ42495172
Sympathetic chemoreflex responses in obstructive sleep apnea and effects of continuous positive airway pressure therapyQ42512473
Release of hypocretin (orexin) during waking and sleep states.Q42523162
Role of inhibitory amino acids in control of hypoglossal motor outflow to genioglossus muscle in naturally sleeping ratsQ42606852
GABAA receptor antagonism at the hypoglossal motor nucleus increases genioglossus muscle activity in NREM but not REM sleepQ42695631
Intermittent hypoxia causes insulin resistance in lean mice independent of autonomic activityQ42738504
Effect of CPAP on insulin resistance and HbA1c in men with obstructive sleep apnoea and type 2 diabetesQ42764571
Influence of obstructive sleep apnea on mortality in patients with heart failureQ43433552
Leftward shift of the interventricular septum and pulsus paradoxus in obstructive sleep apnea syndromeQ43456634
Inhibition of inspiratory upper airway motoneuron activity by phasic volume feedbackQ43501437
The effects of ondansetron on sleep-disordered breathing in the English bulldog.Q43541342
Obstructive sleep apnea-hypopnea and related clinical features in a population-based sample of subjects aged 30 to 70 yr.Q43545269
Impairment of vascular endothelial function and left ventricular filling : association with the severity of apnea-induced hypoxemia during sleepQ43570681
Altered vascular reactivity in arterioles of chronic intermittent hypoxic ratsQ43572857
Effect of Clonidine in Obstructive Sleep ApneaQ43582833
Long-term (5-year) effects of a reduced-fat diet intervention in individuals with glucose intoleranceQ43584172
Effects of acute changes of plasma free fatty acids on intramyocellular fat content and insulin resistance in healthy subjectsQ43651825
Obstructive sleep apnea is a risk factor for death in patients with stroke: a 10-year follow-upQ43715275
Alpha(1B) receptors are the main postsynaptic mediators of adrenergic excitation in brainstem motoneurons, a single-cell RT-PCR studyQ43719691
The motor inhibitory system operating during active sleep is tonically suppressed by GABAergic mechanisms during other statesQ43766622
Evidence for lipid peroxidation in obstructive sleep apneaQ43800410
Continuous positive airway pressure treatment improves pulmonary hemodynamics in patients with obstructive sleep apnea.Q43854250
Systemic and local adrenergic regulation of muscle glucose utilization during hypoglycemia in healthy subjectsQ43901616
Obstructive sleep apnea is independently associated with insulin resistance.Q43903080
Sleep-disordered breathing and insulin resistance in middle-aged and overweight men.Q43903083
Modulation of phrenic motoneuron excitability by ATP: consequences for respiratory-related output in vitro.Q43964415
Effect of ventilatory drive on carbon dioxide sensitivity below eupnea during sleep.Q43980951
A locally generated angiotensin system in rat carotid body.Q44077189
Afferent pathway(s) for pharyngeal dilator reflex to negative pressure in man: a study using upper airway anaesthesiaQ44108678
Effects of CPAP on oxidative stress and nitrate efficiency in sleep apnoea: a randomised trial.Q44117488
Extracellular ATP is an autocrine/paracrine regulator of hypoxia-induced adventitial fibroblast growth. Signaling through extracellular signal-regulated kinase-1/2 and the Egr-1 transcription factor.Q44147029
Brain morphology associated with obstructive sleep apneaQ44159112
Interactions of adenosine, prostaglandins and nitric oxide in hypoxia-induced vasodilatation: in vivo and in vitro studiesQ44161155
Continuous positive airway pressure treatment of mild to moderate obstructive sleep apnea reduces cardiovascular riskQ44168768
Left ventricular systolic dysfunction in patients with obstructive sleep apnea syndromeQ44178011
Nicotinic excitation of rat hypoglossal motoneuronsQ44219024
Suppression of genioglossus muscle tone and activity during reflex hypercapnic stimulation by GABA(A) mechanisms at the hypoglossal motor nucleus in vivoQ44283579
A prospective study of self-reported sleep duration and incident diabetes in womenQ44291206
Longitudinal study of moderate weight change and sleep-disordered breathingQ44313768
Mechanisms of the cerebrovascular response to apnoea in humansQ44317043
The English bulldog: a natural model of sleep-disordered breathingQ44321964
Excitatory effects of hypocretin-1 (orexin-A) in the trigeminal motor nucleus are reversed by NMDA antagonismQ44336714
Pharmacological characterization of 5-hydroxytryptamine-induced apnea in the rat.Q44349360
Effect of Acetazolamide on Hypoxemia during Sleep at High AltitudeQ44383344
Abnormal vasoactive hormones and 24-hour blood pressure in obstructive sleep apneaQ44387214
Effect of ondansetron on moderate obstructive sleep apnoea, a single night, placebo-controlled trialQ44445146
Clinical effects of locally delivered nicotine in obstructive sleep apnea syndromeQ44447296
Alveolar hypoventilation syndrome. Studies of ventilatory control in patients selected for diaphragm pacingQ44470873
Obstructive sleep-disordered breathing with a dominant cyclic alternating pattern--a recognizable polysomnographic variant with practical clinical implicationsQ44508613
Intermittent hypoxia increases insulin resistance in genetically obese miceQ44524266
Sleep apnea in 81 ambulatory male patients with stable heart failure. Types and their prevalences, consequences, and presentationsQ44554087
Parasympathetic hyperresponsiveness and bradyarrhythmias during apnoea in hypertensionQ44573309
Reduction of sleep-disordered breathing after physostigmineQ44575158
Peripheral chemoreceptor hypersensitivity: an ominous sign in patients with chronic heart failureQ44578930
Effect of lifestyle modification on adipokine levels in obese subjects with insulin resistanceQ44584057
Continuous positive airway pressure treatment rapidly improves insulin sensitivity in patients with obstructive sleep apnea syndrome.Q44598192
Chronic intermittent hypoxia impairs endothelium-dependent dilation in rat cerebral and skeletal muscle resistance arteriesQ44598223
Endocrine effects of nasal continuous positive airway pressure in male patients with obstructive sleep apnoeaQ44612095
8-Isoprostane, a marker of oxidative stress, is increased in exhaled breath condensate of patients with obstructive sleep apnea after night and is reduced by continuous positive airway pressure therapy.Q44615125
The modulation by 5-HT of glutamatergic inputs from the raphe pallidus to rat hypoglossal motoneurones, in vitroQ44615235
Controlled trial of continuous positive airway pressure in obstructive sleep apnea and heart failureQ44641932
5-HT at hypoglossal motor nucleus and respiratory control of genioglossus muscle in anesthetized ratsQ44650019
Phox2b controls the development of peripheral chemoreceptors and afferent visceral pathways.Q44662113
Catecholamine-induced vascular wall growth is dependent on generation of reactive oxygen speciesQ44680894
Oxidative stress in severe pulmonary hypertensionQ44710488
Sympathetic activity is reduced by nCPAP in hypertensive obstructive sleep apnoea patientsQ44773562
Oxidative injury to the endoplasmic reticulum in mouse brains after transient focal ischemiaQ44790375
Inhibition of Insulin Release by Norepinephrine in ManQ44804200
Hypoxia causes glucose intolerance in humans.Q44814411
Long-term intermittent hypoxia in mice: protracted hypersomnolence with oxidative injury to sleep-wake brain regionsQ44881796
Sleep-disordered breathing, glucose intolerance, and insulin resistance: the Sleep Heart Health StudyQ45048798
Marked decrease in sleepiness in patients with sleep apnea by etanercept, a tumor necrosis factor-alpha antagonistQ45050579
Urinary catecholamines before and after tracheostomy in patients with obstructive sleep apnea and hypertensionQ45062680
Pre- and postsynaptic modulation of glycinergic and gabaergic transmission by muscarinic receptors on rat hypoglossal motoneurons in vitroQ45181896
Sympathetic vesicovascular reflex induced by acute urinary retention evokes proinflammatory and proapoptotic injury in rat liverQ45197559
Sympathoexcitation by central ANG II: roles for AT1 receptor upregulation and NAD(P)H oxidase in RVLM.Q45214773
Damage to the endoplasmic reticulum and activation of apoptotic machinery by oxidative stress in ischemic neuronsQ45242538
Localization of oxytocin binding sites in the human brainstem and upper spinal cord: an autoradiographic studyQ45304416
Snoring as a risk factor for type II diabetes mellitus: a prospective studyQ45305411
The effect of hypoxia on baroreflexes and pressor sensitivity in sleep apnea and hypertensionQ46306844
Opposing muscarinic and nicotinic modulation of hypoglossal motor output to genioglossus muscle in rats in vivoQ46427662
Dynamics of periodic breathing and arousal during sleep at extreme altitudeQ46440183
Endothelial function and arterial stiffness in minimally symptomatic obstructive sleep apneaQ46460378
Medullary serotonergic neurones modulate the ventilatory response to hypercapnia, but not hypoxia in conscious ratsQ46477266
Effects of continuous positive airway pressure on cardiovascular risk profile in patients with severe obstructive sleep apnea and metabolic syndromeQ46484855
Neurotransmitter phenotypes of intermediate zone reticular formation projections to the motor trigeminal and hypoglossal nuclei in the rat.Q46506326
CHOP plays a pivotal role in the astrocyte death induced by oxygen and glucose deprivationQ46587446
Role of endogenous serotonin in modulating genioglossus muscle activity in awake and sleeping ratsQ46601745
Crossing the apnoeic threshold: causes and consequencesQ47887447
An investigation into the relationship between the severity of obstructive sleep apnoea/hypopnoea syndrome and the vertical position of the hyoid boneQ47887787
Cardiorespiratory function in stable methadone maintenance treatment (MMT) patientsQ47904697
Respiratory responses to intermittent hypoxia in unsedated piglets: relation to substance P binding in brainstemQ47913988
Identification of upper airway anatomic risk factors for obstructive sleep apnea with volumetric magnetic resonance imagingQ47914137
Obstructive Sleep Apnea and the Recurrence of Atrial FibrillationQ47918768
Oral appliance therapy reduces blood pressure in obstructive sleep apnea: a randomized, controlled trialQ47920342
Prevalence and risk factors for sleep-disordered breathing in 8- to 11-year-old children: association with race and prematurityQ47955291
Twenty-four-hour ambulatory blood pressure in children with sleep-disordered breathingQ48022686
A community study of sleep-disordered breathing in middle-aged Chinese women in Hong Kong: prevalence and gender differencesQ48032564
Linkage between brain blood flow and respiratory drive during rapid-eye-movement sleepQ48090991
Interaction between chemoreceptor and stretch receptor inputs at medullary respiratory neuronsQ48112969
CO(2) microdialysis in retrotrapezoid nucleus of the rat increases breathing in wakefulness but not in sleepQ48114282
Pituitary reactivity, androgens and catecholamines in obstructive sleep apnoea. Effects of continuous positive airway pressure treatment (CPAP).Q48125932
Microdialysis delivery of morphine to the hypoglossal nucleus of Wistar rat increases hypoglossal acetylcholine releaseQ48145376
Changes in brain morphology associated with obstructive sleep apneaQ48157373
Substance P-immunoreactive boutons closely appose inspiratory protruder hypoglossal motoneurons in the cat.Q48162363
The apneic threshold during non-REM sleep in dogs: sensitivity of carotid body vs. central chemoreceptorsQ48171557
Silent brain infarction and platelet activation in obstructive sleep apneaQ48251845
Reactivity of cerebral blood flow to carbon dioxide in various types of ischemic cerebrovascular disease: evaluation by the transcranial Doppler methodQ48290664
Effects of specific carotid body and brain hypoxia on respiratory muscle control in the awake goatQ48351953
The vasopressin-induced excitation of hypoglossal and facial motoneurons in young rats is mediated by V1a but not V1b receptors, and is independent of intracellular calcium signallingQ48412192
A negative interaction between brainstem and peripheral respiratory chemoreceptors modulates peripheral chemoreflex magnitude.Q48414961
Relationship between overnight rostral fluid shift and Obstructive Sleep Apnea in nonobese men.Q48418702
Behavior of VRG neurons during the atonia of REM sleep induced by pontine carbachol in decerebrate catsQ48420693
Assessment of intracranial hemodynamics in sleep apnea syndromeQ48425286
Lower body positive pressure increases upper airway collapsibility in healthy subjectsQ48436635
Influence of cerebrovascular function on the hypercapnic ventilatory response in healthy humansQ48437765
Activity of respiratory neurons during NREM sleepQ48437961
Masked hypertension in obstructive sleep apnea syndromeQ48438013
Effects of continuous positive airway pressure treatment and withdrawal in patients with obstructive sleep apnea on arterial stiffness and central BP.Q48440095
Cerebrovascular events on awakening, patent foramen ovale and obstructive sleep apnea syndromeQ48448229
Nocturnal cardiac arrhythmia in patients with obstructive sleep apnea.Q48450974
Left ventricular dysfunction and associated cellular injury in rats exposed to chronic intermittent hypoxiaQ48451162
Chronic intermittent hypoxia increases the CO2 reserve in sleeping dogsQ48454461
Severe sleep apnea and risk of ischemic stroke in the elderly.Q48455002
Increased erythrocyte adhesiveness and aggregation in obstructive sleep apnea syndromeQ48455753
C-reactive protein and fibrinogen in acute stroke patients with and without sleep apneaQ48456610
Selective loss of catecholaminergic wake active neurons in a murine sleep apnea model.Q48457049
Mechanisms of breathing instability in patients with obstructive sleep apneaQ48457747
Treatment of obstructive sleep apnoea leads to enhanced pulmonary vascular nitric oxide releaseQ48463382
Lung volume and collapsibility of the passive pharynx in patients with sleep-disordered breathingQ48463593
Effect of genioglossus contraction on pharyngeal lumen and airflow in sleep apnoea patientsQ48464724
CPAP should not be used for central sleep apnea in congestive heart failure patients.Q48466090
Effects of continuous positive airway pressure on early signs of atherosclerosis in obstructive sleep apneaQ48466428
The association of angiotensin converting enzyme (ACE) polymorphisms with sleep apnea and hypertensionQ48468115
Obstructive sleep apnea, hypertension, and their interaction on arterial stiffness and heart remodelingQ48469363
Comparison of cardiac structural and functional changes in obese otherwise healthy adults with versus without obstructive sleep apneaQ48469918
Chronic intermittent hypoxia predisposes to liver injuryQ48473495
Interaction between the angiotensin-converting enzyme gene insertion/deletion polymorphism and obstructive sleep apnoea as a mechanism for hypertensionQ48474993
Haptoglobin polymorphism is a risk factor for cardiovascular disease in patients with obstructive sleep apnea syndromeQ48620431
Relationship between surface tension of upper airway lining liquid and upper airway collapsibility during sleep in obstructive sleep apnea hypopnea syndromeQ48623276
Cardiorespiratory Effects of Added Dead Space in Patients With Heart Failure and Central Sleep ApneaQ48628760
Elevated levels of C-reactive protein and interleukin-6 in patients with obstructive sleep apnea syndrome are decreased by nasal continuous positive airway pressureQ48634373
Menopausal status and sleep-disordered breathing in the Wisconsin Sleep Cohort StudyQ48634392
Pembrey's dream: the time has come for a long-term trial of nocturnal supplemental nasal oxygen to treat central sleep apnea in congestive heart failureQ48636625
P2 receptor excitation of rodent hypoglossal motoneuron activity in vitro and in vivo: a molecular physiological analysis.Q48637309
Effect of nasal continuous positive airway pressure treatment on blood pressure in patients with obstructive sleep apneaQ48640268
Obstructive sleep apnea can be provocative for right-to-left shunting through a patent foramen ovale.Q48641801
Evidence for left ventricular dysfunction in patients with obstructive sleep apnoea syndromeQ48643754
The male predisposition to pharyngeal collapse: importance of airway lengthQ48646084
Carotid body denervation eliminates apnea in response to transient hypocapniaQ48648039
Prolonged surges of baroreflex-resistant muscle sympathetic drive during periodic breathing.Q48650285
Modulation of upper airway collapsibility during sleep: influence of respiratory phase and flow regimen.Q48650682
Anatomic determinants of sleep-disordered breathing across the spectrum of clinical and nonclinical male subjectsQ48651079
Effect of surfactant on pharyngeal mechanics in sleeping humans: implications for sleep apnoeaQ48652008
Brain angiotensin II: new insights into its role in sympathetic regulationQ48652656
Elevated C-reactive protein in patients with obstructive sleep apneaQ48660954
Apnea-hypopnea threshold for CO2 in patients with congestive heart failureQ48663138
Predictors of sleep-disordered breathing in community-dwelling adults: the Sleep Heart Health StudyQ48664229
Genetics of the apnea hypopnea index in Caucasians and African Americans: I. Segregation analysisQ48665802
The effect of neuromuscular stimulation of the genioglossus on the hypopharyngeal airwayQ48667721
Improvement in neuropsychological performance following surgical treatment for obstructive sleep apnea syndromeQ48668327
Inattention, hyperactivity, and symptoms of sleep-disordered breathingQ48668369
Abnormal palatopharyngeal muscle morphology in sleep-disordered breathingQ48669225
Severe obstructive sleep apnea is associated with left ventricular diastolic dysfunctionQ48670679
Ambulatory blood pressure after therapeutic and subtherapeutic nasal continuous positive airway pressure for obstructive sleep apnoea: a randomised parallel trialQ48672164
Effects of sleep-wake state on the genioglossus vs.diaphragm muscle response to CO(2) in ratsQ48673020
Blood pressure response to chronic episodic hypoxia: the renin-angiotensin systemQ48673050
Contribution of body habitus and craniofacial characteristics to segmental closing pressures of the passive pharynx in patients with sleep-disordered breathingQ48673227
Daytime pulmonary hypertension in patients with obstructive sleep apnea: the effect of continuous positive airway pressure on pulmonary hemodynamicsQ48673471
Obstructive apnea during sleep is associated with peripheral vasoconstrictionQ48673756
Sleep-disordered breathing and coronary artery disease: long-term prognosisQ48677504
Adaptive pressure support servo-ventilation: a novel treatment for Cheyne-Stokes respiration in heart failureQ48684878
Effect of hypoxia on the hypopnoeic and apnoeic threshold for CO(2) in sleeping humansQ48685460
Impact of obstructive sleep apnea on left ventricular mass and diastolic functionQ48691685
Treatment with continuous positive airway pressure is not effective in patients with sleep apnea but no daytime sleepiness. a randomized, controlled trialQ48692215
Nonchemical elimination of inspiratory motor output via mechanical ventilation in sleepQ48693572
Selected Contribution: Pulmonary hypertension in mice following intermittent hypoxiaQ48694134
CPAP treatment does not affect glucose-insulin metabolism in sleep apneic patients.Q48696352
Magnetic resonance imaging of the pharynx in OSA patients and healthy subjectsQ48696514
Blood pressure perturbations caused by subclinical sleep-disordered breathingQ48697545
Role of endothelin in intermittent hypoxia-induced hypertensionQ48701728
Overnight shift from obstructive to central apneas in patients with heart failure: role of PCO2 and circulatory delayQ48704758
Sleep-disordered breathing and cardiovascular disease: cross-sectional results of the Sleep Heart Health StudyQ48704784
Randomized placebo-controlled trial of continuous positive airway pressure on blood pressure in the sleep apnea-hypopnea syndromeQ48705061
Circulating nitric oxide is suppressed in obstructive sleep apnea and is reversed by nasal continuous positive airway pressure.Q48708402
Fibrinogen levels and obstructive sleep apnea in ischemic strokeQ48708426
Platelet function in patients with obstructive sleep apnoea syndromeQ48708646
Impairment of endothelium-dependent vasodilation of resistance vessels in patients with obstructive sleep apneaQ48709586
5-HT2 receptors.Q30339012
The emerging epidemic of obesity in developing countries.Q30352086
The 2008 Carl Ludwig Lecture: retrotrapezoid nucleus, CO2 homeostasis, and breathing automaticityQ30439053
Peripheral chemoreceptor inputs to retrotrapezoid nucleus (RTN) CO2-sensitive neurons in ratsQ30439417
Expression of Phox2b by brainstem neurons involved in chemosensory integration in the adult rat.Q30441790
Upper Airway Muscle Activation Is Augmented in Patients with Obstructive Sleep Apnea Compared with That in Normal SubjectsQ30462513
Pharyngeal fat in obstructive sleep apneaQ30467139
Time-dependent adaptation in the hemodynamic response to hypoxia.Q30484430
Altered upper airway and soft tissue structures in the New Zealand Obese mouseQ30485689
Effect of increased lung volume on sleep disordered breathing in patients with sleep apnoeaQ30489999
Cerebrovascular response to arousal from NREM and REM sleep.Q30493611
Pharyngeal shape and dimensions in healthy subjects, snorers, and patients with obstructive sleep apnoeaQ30496440
Obstructive sleep apnea as a cause of systemic hypertension. Evidence from a canine modelQ30500690
Circulating cardiovascular risk factors in obstructive sleep apnoea: data from randomised controlled trialsQ30954736
Fos expression in orexin neurons varies with behavioral state.Q32062017
Outcome of patients with sleep apnea-associated severe bradyarrhythmias after continuous positive airway pressure therapyQ33145749
Behavioral and anatomical correlates of chronic episodic hypoxia during sleep in the rat.Q33181809
Risk factors and myocardial infarction in patients with obstructive sleep apnea: impact of beta2-adrenergic receptor polymorphismsQ33267996
Ventilatory control and airway anatomy in obstructive sleep apneaQ33432033
Induction of upper airway occlusion in sleeping individuals with subatmospheric nasal pressureQ33471794
Static mechanics of the velopharynx of patients with obstructive sleep apneaQ33485260
Effects of sleep fragmentation on glucose metabolism in normal subjectsQ33577379
"Syndrome Z": the interaction of sleep apnoea, vascular risk factors and heart diseaseQ33588198
Adult obstructive sleep apnea: pathophysiology and diagnosisQ33619089
NO and CO as second messengers in oxygen sensing in the carotid bodyQ33672137
Independent association between obstructive sleep apnea and subclinical coronary artery diseaseQ33700621
Role of peripheral serotonin in the regulation of central sleep apneas in ratsQ33862626
Prognostic value of ambulatory blood pressure : current evidence and clinical implicationsQ33864724
Atherogenic lipids and endothelial dysfunction: mechanisms in the genesis of ischemic syndromesQ33896005
Extreme obesity associated with alveolar hypoventilation; a Pickwickian syndromeQ33969326
Chronic-intermittent hypoxia: a model of sympathetic activation in the rat.Q34017531
Determinants of ventilatory instability and variabilityQ34020046
Multiple sites for central chemoreception: their roles in response sensitivity and in sleep and wakefulnessQ34020071
The endoplasmic reticulum: folding, calcium homeostasis, signaling, and redox controlQ36598776
Obesity and obstructive sleep apnea in childrenQ36650911
Metabolic alterations and systemic inflammation in obstructive sleep apnea among nonobese and obese prepubertal childrenQ36657681
Sleep-disordered breathing and cardiovascular disease: an outcome-based definition of hypopneasQ36657686
Physiological basis for a causal relationship of obstructive sleep apnoea to hypertensionQ36662356
Brainstem respiratory control: substrates of respiratory failure of multiple system atrophyQ36667880
Histological and ultrastructural localization of the kainate receptor subunits, KA2 and GluR6/7, in the rat nervous system using selective antipeptide antibodiesQ36715590
ER stress and diseases.Q36731474
Contribution of male sex, age, and obesity to mechanical instability of the upper airway during sleepQ36776107
Brain structural changes in obstructive sleep apneaQ36800544
Endothelin type A receptor antagonist normalizes blood pressure in rats exposed to eucapnic intermittent hypoxiaQ36807926
Childhood overweight, obesity, and the metabolic syndrome in developing countriesQ36810809
Effects of captopril and oxygen on sleep apnoea in patients with mild to moderate congestive cardiac failureQ36817015
Effects of buspirone on posthypoxic ventilatory behavior in the C57BL/6J and A/J mouse strainsQ36846751
Chronic intermittent hypoxia sensitizes acute hypothalamic-pituitary-adrenal stress reactivity and Fos induction in the rat locus coeruleus in response to subsequent immobilization stressQ36849018
Neurocognitive and behavioral morbidity in children with sleep disordersQ36954283
Aldosterone and vascular inflammationQ37048931
Obesity and obstructive sleep apnea: pathogenic mechanisms and therapeutic approachesQ37077157
Central sleep apnea and Cheyne-Stokes respirationQ37077168
Influence of cerebral blood flow on breathing stabilityQ37139015
Some aspects of clinical relevance in the maturation of respiratory control in infantsQ37141660
Association of nocturnal arrhythmias with sleep-disordered breathing: The Sleep Heart Health StudyQ37144291
Effects of acute intermittent hypoxia on glucose metabolism in awake healthy volunteersQ37190183
A whole-genome scan for obstructive sleep apnea and obesityQ37219579
Reactive oxygen species contribute to sleep apnea-induced hypertension in ratsQ37220930
Prospective study of sleep-disordered breathing and hypertension: the Sleep Heart Health StudyQ37225106
Role of respiratory control mechanisms in the pathogenesis of obstructive sleep disordersQ37267023
Association of sleep-disordered breathing and the occurrence of strokeQ37282690
Lung volume and continuous positive airway pressure requirements in obstructive sleep apneaQ37282714
Association of sleep apnea and type II diabetes: a population-based studyQ37282758
The influence of obstructive sleep apnea and gender on genioglossus activity during rapid eye movement sleep.Q37424477
Impaired vascular regulation in patients with obstructive sleep apnea: effects of continuous positive airway pressure treatmentQ37443285
Molecular mechanisms of cardiovascular disease in OSAHS: the oxidative stress linkQ37502404
Differential roles of opioid receptors in respiration, respiratory disease, and opiate-induced respiratory depressionQ37895578
Positive effect of CPAP treatment on the control of difficult-to-treat hypertensionQ48477044
Endothelial cell apoptosis in obstructive sleep apnea: a link to endothelial dysfunctionQ48478550
Cardiovascular and metabolic effects of CPAP in obese males with OSA.Q48479379
Effects of continuous positive airway pressure on cerebral vascular response to hypoxia in patients with obstructive sleep apnea.Q48480506
Abnormally increased endothelin-1 in plasma during the night in obstructive sleep apnea: relation to blood pressure and severity of diseaseQ48481292
The incremental effect of obstructive sleep apnoea syndrome on arterial stiffness in newly diagnosed essential hypertensive subjectsQ48483708
Acute intermittent hypoxia increases both phrenic and sympathetic nerve activities in the rat.Q48483884
Hyperlipidemia and lipid peroxidation are dependent on the severity of chronic intermittent hypoxiaQ48486252
Twenty-four-hour ambulatory BP in snoring children with obstructive sleep apnea syndromeQ48488274
Recurrent obstructive apneas trigger early systemic inflammation in a rat model of sleep apneaQ48488578
Neuromechanical control of upper airway patency during sleepQ48489322
Fluid shift by lower body positive pressure increases pharyngeal resistance in healthy subjectsQ48489723
Endogenous excitatory drive modulating respiratory muscle activity across sleep-wake statesQ48492029
Association between lipid peroxidation and inflammation in obstructive sleep apnoeaQ48494122
PHOX2B mutation-confirmed congenital central hypoventilation syndrome: presentation in adulthoodQ48494366
Predictors of elevated nuclear factor-kappaB-dependent genes in obstructive sleep apnea syndromeQ48495147
Effect of continuous positive airway pressure on ambulatory BP in patients with sleep apnea and hypertension: a placebo-controlled trial.Q48497132
Changes in the activity of respiratory neurons during sleepQ48497637
Aortic stiffness, flow-mediated dilatation and carotid intima-media thickness in obstructive sleep apnea: non-invasive indicators of atherosclerosisQ48499649
Effect of repetitive hypoxic apnoeas on baroreflex function in humans.Q48500181
Allopurinol improves endothelial function in sleep apnoea: a randomised controlled studyQ48500312
Evidence of impaired hypoxic vasodilation after intermediate-duration hypoxic exposure in humansQ48502864
Increased propensity for apnea in response to acute elevations in left atrial pressure during sleep in the dog.Q48504256
Plasma levels of vascular endothelial markers in obstructive sleep apneaQ48504520
A role of pharyngeal length in obstructive sleep apnea patientsQ48506863
Association between sleep apnea severity and blood coagulability: Treatment effects of nasal continuous positive airway pressureQ48507311
Enhanced sympathetic outflow and decreased baroreflex sensitivity are associated with intermittent hypoxia-induced systemic hypertension in conscious ratsQ48512599
Upper airway function during sleep and wakefulness: experimental studies on normal and anesthetized cats. 1978 [classical article].Q48527421
Selective activation of inflammatory pathways by intermittent hypoxia in obstructive sleep apnea syndromeQ48528105
Sex differences in blood pressure response to intermittent hypoxia in ratsQ48535302
Activation of a distinct arousal state immediately after spontaneous awakening from sleepQ48536891
Increased carotid intima-media thickness and serum inflammatory markers in obstructive sleep apneaQ48538212
Altered blood rheology in obstructive sleep apnea as a mediator of cardiovascular riskQ48544900
Hypoxic response of hypoglossal motoneurones in the in vivo cat.Q48545058
Oxidative stress and left ventricular function with chronic intermittent hypoxia in ratsQ48547568
Chronic liver injury during obstructive sleep apneaQ48550777
Day-night pattern of sudden death in obstructive sleep apneaQ48558148
Elevated production of tumor necrosis factor-alpha by monocytes in patients with obstructive sleep apnea syndromeQ48573657
Association of atrial fibrillation and obstructive sleep apneaQ48587853
Contribution of endothelin-1 to the enhanced carotid body chemosensory responses induced by chronic intermittent hypoxiaQ48593909
Peripheral 5-HT1A receptors are not essential for increased ventilation evoked by systemic 8-OH-DPAT challenge in anaesthetized rats.Q48594766
Whole genome scan for obstructive sleep apnea and obesity in African-American familiesQ48596650
Role of arousals in the pathogenesis of obstructive sleep apneaQ48607323
The influence of lung volume on pharyngeal mechanics, collapsibility, and genioglossus muscle activation during sleepQ48608984
Pulmonary hemodynamics in obstructive sleep apnea: frequency and causes of pulmonary hypertensionQ48615887
Upper airway surface tension: is it a significant cause of airflow obstruction during sleep?Q48616607
Endothelial Function in Obstructive Sleep Apnea and Response to TreatmentQ48616765
Sleep apnea and markers of vascular endothelial function in a large community sample of older adultsQ48616776
Effects of sleep state on ventilatory acclimatization to hypoxia in humansQ48618089
Blood pressure elevation associated with sleep-related breathing disorder in a community sample of white and Hispanic children: the Tucson Children's Assessment of Sleep Apnea studyQ48619087
The placebo effect in heart failureQ38000579
Induction of vascular endothelial growth factor expression and hypoxia-inducible factor 1alpha protein by the oxidative stressor arseniteQ38295592
Intermittent hypoxia induces hyperlipidemia in lean mice.Q38321740
Leptin attenuates respiratory complications associated with the obese phenotypeQ38330703
Concomitant impairment of growth hormone secretion and peripheral sensitivity in obese patients with obstructive sleep apnea syndromeQ38361353
Sleep physiology at high altitudeQ39336577
Objective measurement of patterns of nasal CPAP use by patients with obstructive sleep apneaQ39413535
Induction of periodic breathing during sleep causes upper airway obstruction in humansQ39541605
Peripheral vascular resistance increases after termination of obstructive apneasQ39583304
The effect of upper airway obstruction and arousal on peripheral arterial tonometry in obstructive sleep apneaQ39632284
Unilateral ablation of pre-Botzinger complex disrupts breathing during sleep but not wakefulness.Q39637483
Cardiovascular effects of continuous positive airway pressure in patients with heart failure and obstructive sleep apneaQ39645233
Ambulatory blood pressure in children with obstructive sleep apnoea: a community based studyQ40106632
Intermittent hypoxia reverses the diurnal glucose rhythm and causes pancreatic beta-cell replication in miceQ40151226
Waking and ventilatory responses to laryngeal stimulation in sleeping dogsQ40198315
Brain stem gigantocellular neurons: patterns of activity during behavior and sleep in the freely moving ratQ40218517
Respiratory neurons of the pneumotaxic center during sleep and wakefulnessQ40287122
Is obstructive sleep apnea a common cause of essential hypertension?Q40413671
Pathophysiology of cor pulmonale in chronic obstructive pulmonary disease. Part two.Q40628951
Relation of sleep-disordered breathing to cardiovascular disease risk factors: the Sleep Heart Health StudyQ40699336
Pathophysiology of cor pulmonale in chronic obstructive pulmonary disease. Part One.Q40704030
REM sleep-like atonia of hypoglossal (XII) motoneurons is caused by loss of noradrenergic and serotonergic inputsQ41065785
Correlation between oscillations in ventilation and frequency content of the electroencephalogramQ41116400
Effects of pH on vascular tension: which are the important mechanisms?Q41155753
The pharyngeal critical pressure. The whys and hows of using nasal continuous positive airway pressure diagnosticallyQ41169490
The pulmonary circulation in cystic fibrosisQ41193266
Obstructive sleep apnea treated by independently adjusted inspiratory and expiratory positive airway pressures via nasal mask. Physiologic and clinical implicationsQ41204871
Upper airway occlusion during sleep in patients with Cheyne-Stokes respirationQ41378669
Presynaptic inhibition by serotonin: a possible mechanism for switching motor output of the hypoglossal nucleus.Q41403333
Excitatory drive to the respiratory system in REM sleep.Q41403351
Changes in inspiratory muscle electrical activity and upper airway resistance during periodic breathing induced by hypoxia during sleepQ41455172
Influence of reticular mechanisms upon hypoglossal, trigeminal and phrenic activitiesQ41477112
Long-term cardiopulmonary sequelae in patients with sleep apnea and chronic lung diseaseQ41481128
Reversal of obstructive sleep apnoea by continuous positive airway pressure applied through the naresQ34054705
Effects of intravenous and dietary lipid challenge on intramyocellular lipid content and the relation with insulin sensitivity in humansQ34099337
Increased adhesion molecules expression and production of reactive oxygen species in leukocytes of sleep apnea patientsQ34122262
Neonatal intermittent hypoxia impairs dopamine signaling and executive functioning.Q34170090
Sleep-induced apnea syndrome. Prevalence of cardiac arrhythmias and their reversal after tracheostomyQ34174067
Medullary serotonergic network deficiency in the sudden infant death syndrome: review of a 15-year study of a single datasetQ34178799
Episodic neonatal hypoxia evokes executive dysfunction and regionally specific alterations in markers of dopamine signalingQ34180887
Continuous positive airway pressure therapy for treating sleepiness in a diverse population with obstructive sleep apnea: results of a meta-analysis.Q34182043
Glucose clamp technique: a method for quantifying insulin secretion and resistanceQ34191986
Physiologic, metabolic, and muscle fiber type characteristics of musculus uvulae in sleep apnea hypopnea syndrome and in snorersQ34192318
Extracellular matrix remodeling in the vascular wallQ34294293
Efficacy of positive airway pressure and oral appliance in mild to moderate obstructive sleep apneaQ34327395
Vascular endothelial dysfunction: does tetrahydrobiopterin play a role?Q34341995
A double-blind, randomized trial of sabeluzole--a putative glutamate antagonist--in obstructive sleep apnea.Q34394242
Role of superoxide in angiotensin II-induced but not catecholamine-induced hypertensionQ34415739
Acetazolamide improves central sleep apnea in heart failure: a double-blind, prospective studyQ34461570
Obstructive sleep apnea as a risk factor for stroke and deathQ34466726
Chronic intermittent hypoxia activates nuclear factor-kappaB in cardiovascular tissues in vivoQ34504254
Association of sleep-disordered breathing, sleep apnea, and hypertension in a large community-based study. Sleep Heart Health StudyQ34508280
Obstructive sleep apnea and the prefrontal cortex: towards a comprehensive model linking nocturnal upper airway obstruction to daytime cognitive and behavioral deficitsQ34546476
Improved sex-specific criteria of left ventricular hypertrophy for clinical and computer interpretation of electrocardiograms: validation with autopsy findingsQ34562725
Equivalence of the insulin sensitivity index in man derived by the minimal model method and the euglycemic glucose clampQ34563818
Hypoxia-induced pulmonary vascular remodeling: cellular and molecular mechanismsQ34569861
Pathologically-activated therapeutics for neuroprotection: mechanism of NMDA receptor block by memantine and S-nitrosylationQ34628531
L-tryptophan in the treatment of impaired respiration in sleepQ34708766
Trends in opioid prescribing by race/ethnicity for patients seeking care in US emergency departmentsQ34732249
Donepezil improves obstructive sleep apnea in Alzheimer disease: a double-blind, placebo-controlled studyQ34736623
Tonic activity in the respiratory system in wakefulness, NREM and REM sleep.Q34768252
The structural basis of pulmonary hypertension in chronic lung disease: remodelling, rarefaction or angiogenesis?Q34996430
Hypoxic activation of adventitial fibroblasts: role in vascular remodelingQ35022227
Characterization of the in vitro effects of 5-hydroxytryptamine (5-HT) on identified neurones of the rat dorsal motor nucleus of the vagus (DMV).Q35041694
Role of oxidative stress in atherosclerosisQ35088521
Effect of oxygen in obstructive sleep apnea: role of loop gain.Q35095307
Contributions of upper airway mechanics and control mechanisms to severity of obstructive apneaQ35139520
Cerebral hemodynamic changes in sleep apnea syndrome and effect of continuous positive airway pressure treatmentQ48786336
State-related changes in upper airway caliber and surrounding soft-tissue structures in normal subjectsQ48786979
Instability of ventilatory control in patients with obstructive sleep apneaQ48786991
Patterned cardiovascular responses to sleep and nonrespiratory arousals in a porcine modelQ48787353
Respiratory-related activity in hypoglossal neurons across sleep-waking states in catsQ48793543
Surface tension forces in sleep apnea: the role of a soft tissue lubricant: a randomized double-blind, placebo-controlled trialQ48799429
Systemic and myocardial hemodynamics during periodic obstructive apneas in sedated pigsQ48801747
Ventilatory effects of specific carotid body hypocapnia in dogs during wakefulness and sleepQ48805502
Spontaneous platelet activation and aggregation during obstructive sleep apnea and its response to therapy with nasal continuous positive airway pressure. A preliminary investigationQ48806749
Surges of muscle sympathetic nerve activity during obstructive apnea are linked to hypoxemiaQ48809642
Effects of body position on the upper airway of patients with obstructive sleep apneaQ48811689
Acute systemic blood pressure elevation in obstructive and nonobstructive breath hold in primatesQ48812069
Combined hypoxia and hypercapnia evokes long-lasting sympathetic activation in humansQ48812084
Familial aggregates in obstructive sleep apnea syndrome.Q48819246
Cardiac hypertrophy in obstructive sleep apnea syndromeQ48819259
Treatment of apneustic respiratory disturbance with a serotonin-receptor agonistQ48820909
Effects of excitatory amino acid antagonists on the phasic depolarizing events that occur in lumbar motoneurons during REM periods of active sleepQ48820984
Pharyngeal narrowing/occlusion during central sleep apneaQ48821308
Respiratory and cardiovascular responses to increased and decreased carotid sinus pressure in sleeping dogsQ48821325
Sleep apnoea and nocturnal angina.Q48821990
Pulmonary hypertension in obstructive sleep apnoeaQ48822927
Platelet Function and Fibrinolytic Activity in Hypertensive and Normotensive Sleep Apnea PatientsQ48823182
Body fat distribution and sleep apnea severity in womenQ48824946
Family studies in patients with the sleep apnea-hypopnea syndromeQ48825036
Reduction in sympathetic activity after long-term CPAP treatment in sleep apnoea: cardiovascular implicationsQ48825408
Reversal of sinus arrest and atrioventricular conduction block in patients with sleep apnea during nasal continuous positive airway pressureQ48827357
Sleep apnea in patients with hemispheric strokeQ48827370
Obstructive sleep apnea in obese noninsulin-dependent diabetic patients: effect of continuous positive airway pressure treatment on insulin responsivenessQ48829306
Impairment of cerebral perfusion during obstructive sleep apneasQ48829441
Effects of REM sleep on the ventilatory response to airway occlusion in the dog.Q48830297
Central respiratory activity in rapid eye movement sleep: augmenting and late inspiratory cells [corrected]Q48830306
Respiratory muscle activity during sleep-induced periodic breathing in the elderlyQ48830987
Apnea after normocapnic mechanical ventilation during NREM sleepQ48831015
Insulin levels, blood pressure and sleep apnea.Q48832253
Plasma insulin and lipid levels in untreated obstructive sleep apnoea and snoring; their comparison with matched controls and response to treatmentQ48833064
Interaction of hyperventilation and arousal in the pathogenesis of idiopathic central sleep apneaQ48835890
Acute effects of transdermal nicotine on sleep architecture, snoring, and sleep-disordered breathing in nonsmokersQ48835975
A volume-dependent apneic threshold during NREM sleep in the dog.Q48843287
Presynaptic depression of excitatory synaptic inputs to rat hypoglossal motoneurons by muscarinic M2 receptorsQ48846731
ST-segment depression during obstructive sleep apneaQ48846744
Effect of chemoreceptor stimulation and inhibition on total pulmonary resistance in humans during NREM sleepQ48847268
Pulmonary hypertension and hypoxemia in obstructive sleep apnea syndromeQ48851176
Dynamic upper airway imaging during awake respiration in normal subjects and patients with sleep disordered breathingQ48859276
Pharyngeal narrowing and closing pressures in patients with obstructive sleep apneaQ48862328
Effects of rapid-eye-movement sleep on the apneic threshold in dogsQ48863592
Laryngeal response to passively induced hypocapnia during NREM sleep in normal adult humansQ48863604
Hypocretin (orexin) input to trigeminal and hypoglossal motoneurons in the cat: a double-labeling immunohistochemical studyQ48864091
Continuous positive airway pressure treatment. Effects on growth hormone, insulin and glucose profiles in obstructive sleep apnea patientsQ48865967
ST-segment depression during sleep in obstructive sleep apneaQ48867762
Augmented resting sympathetic activity in awake patients with obstructive sleep apneaQ48867897
Neurocirculatory consequences of negative intrathoracic pressure vs. asphyxia during voluntary apneaQ48868124
Molecular and physiologic basis of obstructive sleep apneaQ35151647
Hypertension and obstructive sleep apneaQ35209080
Neck soft tissue and fat distribution: comparison between normal men and women by magnetic resonance imagingQ35533055
Pulmonary arterial hypertension in patients with sleep apnoea syndromeQ35533481
Association of serum leptin with hypoventilation in human obesityQ35534789
Craniofacial profile in Asian and white subjects with obstructive sleep apnoeaQ35537704
Serotonin2 receptors in the nucleus tractus solitarius: characterization and role in the baroreceptor reflex arcQ35545559
Effects of nasal continuous positive airway pressure on soluble cell adhesion molecules in patients with obstructive sleep apnea syndromeQ48710576
Reduced alpha- and beta(2)-adrenergic vascular response in patients with obstructive sleep apneaQ48711993
Angiotensin-converting enzyme gene insertion/deletion (I/D) polymorphism in hypertensive patients with different degrees of obstructive sleep apneaQ48712448
Neurocirculatory consequences of intermittent asphyxia in humansQ48712967
Upper airway muscle responsiveness to rising PCO(2) during NREM sleepQ48712976
Cardiac rhythm disturbances in the obstructive sleep apnea syndrome: effects of nasal continuous positive airway pressure therapyQ48713863
Endogenous excitatory drive to the respiratory system in rapid eye movement sleep in catsQ48714864
Enhanced release of superoxide from polymorphonuclear neutrophils in obstructive sleep apnea. Impact of continuous positive airway pressure therapyQ48716348
Association of hypertension and sleep-disordered breathingQ48716637
Increased vasoconstrictor sensitivity in obstructive sleep apneaQ48716681
Local mechanisms drive genioglossus activation in obstructive sleep apnea.Q48722362
Ventilatory responses to specific CNS hypoxia in sleeping dogsQ48722647
Predictors of improvements in daytime function outcomes with CPAP therapyQ48728579
Neural and local effects of hypoxia on cardiovascular responses to obstructive apneaQ48728776
Endothelin-1 plasma levels are not elevated in patients with obstructive sleep apnoeaQ48729153
Sleep-disordered breathing among patients with first-ever strokeQ48729312
Time course of sleep-related breathing disorders in first-ever stroke or transient ischemic attackQ48731769
Effects of nasal O2 on sleep-related disordered breathing in ambulatory patients with stable heart failure.Q48735827
Hypoglossal motoneurons are postsynaptically inhibited during carbachol-induced rapid eye movement sleepQ48736196
Nocturnal continuous positive airway pressure decreases daytime sympathetic traffic in obstructive sleep apnea.Q48737296
Acute and chronic effects of airway obstruction on canine left ventricular performanceQ48737323
Nocturnal ischemic events in patients with obstructive sleep apnea syndrome and ischemic heart disease: effects of continuous positive air pressure treatmentQ48737933
The effects of trazodone with L-tryptophan on sleep-disordered breathing in the English bulldogQ48739007
Risk factors for central and obstructive sleep apnea in 450 men and women with congestive heart failureQ48741847
Chronic intermittent hypoxia increases haematocrit and causes right ventricular hypertrophy in the rat.Q48742479
An independent association between obstructive sleep apnoea and coronary artery diseaseQ48744179
Patients with obstructive sleep apnea have an abnormal peripheral vascular response to hypoxiaQ48744641
Changes in intra-abdominal visceral fat and serum leptin levels in patients with obstructive sleep apnea syndrome following nasal continuous positive airway pressure therapyQ48748953
Sleep apnea syndrome and cerebral hemodynamicsQ48752136
The effect of adenotonsillectomy on serum insulin-like growth factor-I and growth in children with obstructive sleep apnea syndromeQ48755930
Manifestation of pulmonary hypertension during REM sleep in obstructive sleep apnea syndromeQ48762066
Acute and chronic blood pressure response to recurrent acoustic arousal in ratsQ48762593
Risk factors for sleep-disordered breathing in children. Associations with obesity, race, and respiratory problemsQ48764895
Daytime pulmonary hemodynamics in patients with obstructive sleep apnea without lung diseaseQ48764914
Effects of inhaled carbon dioxide and oxygen on cheyne-stokes respiration in patients with heart failureQ48764933
Leptin prevents respiratory depression in obesityQ48764953
Inhibition of inspiratory motor output by high-frequency low-pressure oscillations in the upper airway of sleeping dogs.Q48765076
Sleep apnea in acute cerebrovascular diseases: final report on 128 patientsQ48766715
Baroreflex control of heart rate in a canine model of obstructive sleep apneaQ48767973
Effects of obstructive sleep apnea on endothelin-1 and blood pressure.Q48768740
Influence of pulmonary capillary wedge pressure on central apnea in heart failureQ48768829
Selective potentiation of peripheral chemoreflex sensitivity in obstructive sleep apnea.Q48770394
Effect of serotonin uptake inhibition on breathing during sleep and daytime symptoms in obstructive sleep apnea.Q48771805
Acute effects of nasal continuous positive airway pressure on 24-hour blood pressure and catecholamines in patients with obstructive sleep apneaQ48772436
Polysomnography and maintenance of wakefulness test as predictors of CPAP effectiveness in obstructive sleep apneaQ48773101
Chronic intermittent hypoxia increases sympathetic responsiveness to hypoxia and hypercapniaQ48774498
Peripheral neuropathy in sleep apnea. A tissue marker of the severity of nocturnal desaturation.Q48775593
Progressive retropalatal narrowing preceding obstructive apnea.Q48779079
Impairment of daytime cerebrovascular reactivity in patients with obstructive sleep apnoea syndrome.Q48779531
Susceptibility to periodic breathing with assisted ventilation during sleep in normal subjectsQ48785494
Activity of serotonin-containing neurons in the nucleus raphe pallidus of freely moving catsQ48872432
Persistent neuropsychological deficits and vigilance impairment in sleep apnea syndrome after treatment with continuous positive airways pressure (CPAP).Q48873426
Nasal continuous positive airway pressure in chronic heart failure with sleep-disordered breathingQ48874085
Determinants of poststimulus potentiation in humans during NREM sleepQ48882115
Stroke volume and cardiac output decrease at termination of obstructive apneasQ48882125
Repetitive, episodic hypoxia causes diurnal elevation of blood pressure in ratsQ48886060
Carotid chemoreceptors, systemic blood pressure, and chronic episodic hypoxia mimicking sleep apneaQ48886308
Histopathologic changes in snoring and obstructive sleep apnea syndromeQ48895331
Prevention of airway obstructions during sleep in infants with breath-holding spells by means of oral belladonna: a prospective double-blind crossover evaluationQ48898591
Response of Obstructive Sleep Apnea to Fluoxetine and ProtriptylineQ48902274
Effect of Hypercapnia on Total Pulmonary Resistance during Wakefulness and during NREM SleepQ48902370
Left ventricular hypertrophy independent of hypertension in patients with obstructive sleep apnoea.Q48919880
Effects of sleep-induced increases in upper airway resistance on ventilationQ48922295
Waking and genioglossus muscle responses to upper airway pressure oscillation in sleeping dogsQ48923432
Effect of lung inflation on pulmonary resistance during NREM sleepQ48925606
Cephalometric evaluation of pharyngeal obstructive factors in patients with sleep apneas syndromeQ48930190
Pulmonary hypertension, hypoxemia, and hypercapnia in obstructive sleep apnea patientsQ48937004
Morphology of the uvula in obstructive sleep apneaQ48938620
Respiration and abnormal sleep in patients with congestive heart failureQ48938749
Neuroendocrine dysfunction in sleep apnea: reversal by continuous positive airways pressure therapyQ48946653
Presynaptic inhibition of glutamatergic synaptic transmission to rat motoneurons by serotoninQ48949615
Is high and fluctuating muscle nerve sympathetic activity in the sleep apnoea syndrome of pathogenetic importance for the development of hypertension?Q48950794
Daytime pulmonary hypertension in patients with obstructive sleep apnea syndromeQ48955167
Inhibition of inspiratory muscle activity during sleep. Chemical and nonchemical influencesQ48956427
Obstructive sleep apnea and cephalometric roentgenograms. The role of anatomic upper airway abnormalities in the definition of abnormal breathing during sleepQ48957305
Sleep apnea in olivopontocerebellar degeneration: treatment with trazodoneQ48959349
Upper airway pressure-flow relationships in obstructive sleep apneaQ48960423
Serotonergic effects on hypoglossal neural activity and reflex responsesQ48965282
Comparison of the response of diaphragm and upper airway dilating muscle activity in sleeping catsQ48969055
Recombinant tumor necrosis factor and interleukin 1 enhance slow-wave sleepQ48983400
Effect of hypoxia-induced periodic breathing on upper airway obstruction during sleepQ48985430
A sleep-induced apneic threshold and its consequencesQ49011346
A possible mechanism for mixed apnea in obstructive sleep apneaQ49012144
Serotonergic and noradrenergic effects on respiratory neural discharge in the medullary slice preparation of neonatal ratsQ49017292
Sleep apnea and pulmonary hypertensionQ49018369
Undiagnosed sleep apnea in patients with essential hypertensionQ49038713
Role of daytime hypoxemia in the pathogenesis of right heart failure in the obstructive sleep apnea syndromeQ49041960
Sleep apnea syndrome and essential hypertensionQ49045570
Nicotine: a different approach to treatment of obstructive sleep apneaQ49054158
Induction of airway collapse with subatmospheric pressure in awake patients with sleep apneaQ49073309
Upper airway morphology in patients with idiopathic obstructive sleep apneaQ49083087
Effects of slow wave sleep on ventilatory compensation to inspiratory elastic loadingQ49087961
Reduced stroke volume related to pleural pressure in obstructive sleep apneaQ49098116
Mechanisms of hypoxia-induced periodic breathing during sleep in humansQ49104073
Investigating the relationship between stroke and obstructive sleep apnea.Q49105399
Interaction of sleep state and chemical stimuli in sustaining rhythmic ventilationQ49105780
Cardiac arrhythmia and conduction disturbances during sleep in 400 patients with sleep apnea syndromeQ49105960
Inspiratory and expiratory partitioning of airway resistance during sleep in patients with sleep apneaQ49112575
Cephalometric analyses and flow-volume loops in obstructive sleep apnea patientsQ49122316
Factors inducing periodic breathing in humans: a general modelQ49134449
Changes in cerebral blood flow in patients with severe congestive cardiac failure before and after captopril treatmentQ70216514
Influence of upper airway pressure changes on genioglossus muscle respiratory activityQ70219449
Oropharyngeal muscle tone in obstructive sleep apnea before and after strychnineQ70742224
5-HT2 receptor-controlled modulation of medullary respiratory neurones in the catQ70845792
The effects of serotonin antagonists in an animal model of sleep-disordered breathingQ70906266
Influence of treatment on muscle sympathetic nerve activity in sleep apneaQ71046220
Obstructive sleep apnea syndrome and circadian rhythms of hormones and cytokinesQ71078731
Effects of NCPAP therapy on fibrinogen levels in obstructive sleep apnea syndromeQ71147324
Hypoxemia during apnea in normal subjects: mechanisms and impact of lung volumeQ71168888
Laryngeal receptors responding to transmural pressure, airflow and local muscle activityQ71202053
Pharmacological characterization of serotonin receptors in the facial motor nucleus: a microiontophoretic studyQ71265425
Phasic volume-related feedback on upper airway muscle activityQ71300070
Negative pressure-induced deformation of the upper airway causes central apnea in awake and sleeping dogsQ71314467
Neurocirculatory consequences of abrupt change in sleep state in humansQ71314529
Diaphragmatic and genioglossal electromyogram responses to isocapnic hypoxia in humansQ71569447
Effects of vasodilators on hypoxic pulmonary vasoconstriction in normal manQ71618840
Upper airway and soft tissue anatomy in normal subjects and patients with sleep-disordered breathing. Significance of the lateral pharyngeal wallsQ71796369
Airway obstruction during sleep increases blood pressure without arousalQ71886003
Effect of recurrent episodic hypocapnic, eucapnic, and hypercapnic hypoxia on systemic blood pressureQ71891689
Modification of mastication and respiration during swallowing in the adult humanQ71958971
ATP modulation of synaptic transmission in the spinal substantia gelatinosaQ72240775
Determinants of maximal expiratory flow from the lungsQ72317246
Ventilatory afterdischarge and central respiratory drive interactions in the awake goatQ72403158
Development of thyrotropin-releasing hormone and norepinephrine potentiation of inspiratory-related hypoglossal motoneuron discharge in neonatal and juvenile mice in vitroQ72616516
Role of hyperventilation in the pathogenesis of central sleep apneas in patients with congestive heart failureQ72860707
Sleep-related myocardial ischemia and sleep structure in patients with obstructive sleep apnea and coronary heart diseaseQ73092761
Visceral fat accumulation as an important risk factor for obstructive sleep apnoea syndrome in obese subjectsQ73092998
Effects of inhaled CO2 and added dead space on idiopathic central sleep apneaQ73165458
Role of 5HT1 receptors in the control of hypoglossal motoneurons in vivoQ73187641
Comparison of regional cerebral blood flow and glucose metabolism in the normal brain: effect of agingQ73251630
Elevation of plasma cytokines in disorders of excessive daytime sleepiness: role of sleep disturbance and obesityQ73320092
Circulating endothelin-1 in obstructive sleep apneaQ73544211
Cerebrovascular reactivity and subcortical infarctionsQ73735298
Hemodynamics, cerebral circulation, and oxygen saturation in Cheyne-Stokes respirationQ73807063
The effect of altitude hypoxia on glucose homeostasis in menQ73831550
Left ventricular volume in patients with heart failure and Cheyne-Stokes respiration during sleepQ73885902
Pulmonary hypertension in patients with obstructive sleep apnea syndromeQ73912549
An induced blood pressure rise does not alter upper airway resistance in sleeping humansQ74126007
Sleep-disordered breathing in childrenQ74129549
Association of low PaCO2 with central sleep apnea and ventricular arrhythmias in ambulatory patients with stable heart failureQ74137585
Hypertension caused by chronic intermittent hypoxia--influence of chemoreceptors and sympathetic nervous systemQ74261920
Angiotensin II-nitric oxide interaction on sympathetic outflow in conscious rabbitsQ74324545
Contribution of tonic chemoreflex activation to sympathetic activity and blood pressure in patients with obstructive sleep apneaQ74405737
Heart block in patients with obstructive sleep apnoea: pathogenetic factors and effects of treatmentQ74463133
Exposure to hypoxia produces long-lasting sympathetic activation in humansQ74542436
Respiration and wakefulness in manQ76458458
Enhanced activity of carotid body chemoreceptors in rabbits with heart failure: role of nitric oxideQ77293229
Quantitation of chemoreceptor activity: interrelation of hypoxia and hypercapniaQ78929106
5-HT activates vagal afferent cell bodies in vivo: role of 5-HT2 and 5-HT3 receptorsQ79213470
Role of the renin-angiotensin system in the systemic microvascular inflammation of alveolar hypoxiaQ79511818
Angiotensin II induces endothelial xanthine oxidase activation: role for endothelial dysfunction in patients with coronary diseaseQ79597968
Chronic intermittent hypoxia induces hypoxia-evoked catecholamine efflux in adult rat adrenal medulla via oxidative stressQ79733817
5-HT evokes sensory long-term facilitation of rodent carotid body via activation of NADPH oxidaseQ80057764
Angiotensin II enhances carotid body chemoreflex control of sympathetic outflow in chronic heart failure rabbitsQ83227640
Ventilatory adaptations to resistive loading during wakefulness and non-REM sleepQ49146036
Pathogenesis of apneas in hypersomnia-sleep apnea syndromeQ49148060
Sleep-disordered breathing and poor functional outcome after strokeQ49157537
Activity of norepinephrine-containing locus coeruleus neurons in behaving rats anticipates fluctuations in the sleep-waking cycleQ49162619
Depressed baroreflex sensitivity in patients with obstructive sleep apnea.Q50993314
Sleep-disordered breathing in women: occurrence and association with coronary artery disease.Q50999358
Studies on the respiratory response to disturbances of acid-base balance, with deductions concerning the ionic composition of cerebral interstitial fluidQ51238223
Polygraphic study of the episodic diurnal and nocturnal (hypnic and respiratory) manifestations of the pickwick syndromeQ51239571
The reticular activating system and respiratory regulation in the cat.Q51285533
Diet-induced muscle insulin resistance in rats is ameliorated by acute dietary lipid withdrawal or a single bout of exercise: parallel relationship between insulin stimulation of glucose uptake and suppression of long-chain fatty acyl-CoA.Q51572827
Serotonin 1A-receptor activation suppresses respiratory apneusis in the cat.Q51633937
Reactive oxygen species in the plasticity of respiratory behavior elicited by chronic intermittent hypoxia.Q51690158
Upper airway negative-pressure effects on respiratory activity of upper airway muscles.Q51848221
Respiratory-related hypoglossal nerve activity: influence of anesthetics.Q51851882
Haptoglobin phenotype is an independent risk factor for cardiovascular disease in individuals with diabetes: The Strong Heart Study.Q52026600
Interaction of cross-sectional area, driving pressure, and airflow of passive velopharynx.Q52256635
Pulmonary hemodynamics in the obstructive sleep apnea syndrome. Results in 220 consecutive patients.Q52312223
Dynamic imaging of the upper airway during respiration in normal subjects.Q52397685
Influence of passive changes of lung volume on upper airways.Q52866740
Maximum Nasal Inspiratory Flow and Nasal ResistanceQ53008986
Apparent CBF decrease with normal aging due to partial volume effects: MR-based partial volume correction on CBF SPECT.Q53574032
Pharmacological studies of facial motoneurones in the rat.Q53701417
Neural mechanism of the pressor response to obstructive and nonobstructive apnea.Q53794129
Central neural respiratory stimulatory effect of active respiration.Q54122856
Actions of norepinephrine on rat hypoglossal motoneurons.Q54158533
Adenosine suppresses excitatory glutamatergic inputs to rat hypoglossal motoneurons in vitro.Q54197519
Influence of lung volume dependence of upper airway resistance during continuous negative airway pressure.Q54198339
Effect of tracheotomy in hypersomnia with periodic respiration.Q54253301
Nasal and pharyngeal resistance after topical mucosal vasoconstriction in normal humans.Q54284802
Thoracic influence on upper airway patency.Q54373761
Hemodynamics of the Mueller maneuver in man: right and left heart micromanometry and Doppler echocardiography.Q54397477
Effect of beta-adrenergic agonists on apnea reflexes in newborn lambs.Q54500793
Effect of chemical stimuli on nerves supplying upper airway muscles.Q54520337
Essential role of vascular endothelial growth factor in angiotensin II-induced vascular inflammation and remodeling.Q54709411
Genetically reduced antioxidative protection and increased ischemic heart disease risk: The Copenhagen City Heart Study.Q55037941
Superiority of Ambulatory Over Clinic Blood Pressure Measurement in Predicting MortalityQ57085545
The Partial 5-Hydroxytryptamine1A Receptor Agonist Buspirone does not Antagonize Morphine-induced Respiratory Depression in HumansQ60678545
Sleep-Disordered Breathing in Men With Coronary Artery DiseaseQ60687134
Effects of graded reduction of brain blood flow on chemical control of breathingQ66993783
Pathogenesis of upper airway occlusion during sleepQ67355497
Regulation of respiration in sleeping dogsQ67738701
Hemodynamics in sleep-induced apnea. Studies during wakefulness and sleepQ67876016
Ventricular Function in Snorers and Patients with Obstructive Sleep ApneaQ68194031
Pulmonary arterial muscularity and right ventricular hypertrophy in chronic bronchitis and emphysemaQ68543610
Insomnia with sleep apnea: a new syndromeQ68665477
Noradrenergic modulation of the masseteric reflex in behaving cats. I. Pharmacological studiesQ68700993
Serotonin and co-localized peptides: effects on spinal motoneuron excitabilityQ68951049
Variable site of airway narrowing among obstructive sleep apnea patientsQ69663735
P433issue1
P921main subjectsleep apneaQ213600
pathophysiologyQ1135939
sleepQ35831
P304page(s)47-112
P577publication date2010-01-01
P1433published inPhysiological ReviewsQ1091827
P1476titlePathophysiology of sleep apnea
P478volume90

Reverse relations

cites work (P2860)
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Q48367687Are home ventilators able to guarantee a minimal tidal volume?
Q37301951Are nocturnal breathing, sleep, and cognitive performance impaired at moderate altitude (1,630-2,590 m)?
Q44601208Arousals are frequent and associated with exacerbated blood pressure response in patients with primary hypertension
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Q39123858Association Between Sleep-Disordered Breathing and Hypertensive Disorders of Pregnancy and Gestational Diabetes Mellitus
Q47739016Association between Sleep Disordered Breathing and Nighttime Driving Performance in Mild Cognitive Impairment
Q35100289Association between asthma and risk of developing obstructive sleep apnea
Q92000972Association of Adipocytokines With Carotid Intima Media Thickness and Arterial Stiffness in Obstructive Sleep Apnea Patients
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Q47947249Augmented cardiovascular responses to episodes of repetitive compared with isolated respiratory events in preschool children with sleep-disordered breathing.
Q58484011Baroreflex control of muscle sympathetic nerve activity as a mechanism for persistent sympathoexcitation following acute hypoxia in humans
Q42128532Bench test evaluation of adaptive servoventilation devices for sleep apnea treatment
Q60919539Benzodiazepines Associated With Acute Respiratory Failure in Patients With Obstructive Sleep Apnea
Q41457855Blockade of Na+/H+ exchanger type 3 causes intracellular acidification and hyperexcitability via inhibition of pH-sensitive K+ channels in chemosensitive respiratory neurons of the dorsal vagal nucleus in rats
Q37628119Bupropion response on sleep quality in patients with depression: implications for increased cardiovascular disease risk
Q30411461C1 neurons: the body's EMTs
Q38076337CBCT assessment of upper airway changes and treatment outcomes of obstructive sleep apnoea: a systematic review
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Q35366061Cardiac autonomic control in the obstructive sleep apnea
Q61454624Cardiac rhythm disorders in obstructive sleep apnea
Q35144144Cardio-respiratory coordination increases during sleep apnea.
Q55241616Cardiovascular Disease Risk in Obstructive Sleep apnea: An Update.
Q47731161Cardiovascular Effects of Continuous Positive Airway Pressure Treatment in Patients With Obstructive Sleep Apnea: A Meta-Analysis.
Q48275734Cardiovascular consequences of sleep apnea
Q92090998Cardiovascular morbidities of obstructive sleep apnea and the role of circulating extracellular vesicles
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Q42722134Career perspective: Jerome A. Dempsey
Q88779835Carotid Body Ablation: a New Target to Address Central Autonomic Dysfunction
Q28076487Carotid body chemoreceptors, sympathetic neural activation, and cardiometabolic disease
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Q34495929Carotid body potentiation during chronic intermittent hypoxia: implication for hypertension
Q34419319Carotid body, insulin, and metabolic diseases: unraveling the links
Q40121464Catecholaminergic A1/C1 neurons contribute to the maintenance of upper airway muscle tone but may not participate in NREM sleep-related depression of these muscles
Q37513401Central and peripheral factors contributing to obstructive sleep apneas
Q39999646Central respiratory chemosensitivity and cerebrovascular CO2 reactivity: a rebreathing demonstration illustrating integrative human physiology
Q91812122Central sleep apnea: misunderstood and mistreated!
Q36366284Cerebrovascular consequences of obstructive sleep apnea
Q34887628Cerebrovascular reactivity in young subjects with sleep apnea.
Q38716737Change in End-Expiratory Lung Volume During Sleep in Patients at Risk for Obstructive Sleep Apnea
Q34553063Chemogenetic stimulation of the hypoglossal neurons improves upper airway patency
Q26825346Chemoreception and asphyxia-induced arousal
Q34598170Chemoreflexes, sleep apnea, and sympathetic dysregulation
Q40471661Chronic Influences of Obstructive Sleep Apnea on Cerebral Venous Flow.
Q36541176Chronic Intermittent Hypoxia Alters Local Respiratory Circuit Function at the Level of the preBötzinger Complex.
Q41705938Chronic Intermittent Hypoxia Differentially Impacts Different States of Inspiratory Activity at the Level of the preBötzinger Complex
Q26783756Chronic hypoventilation syndromes and sleep-related hypoventilation
Q38593059Chronic intermittent hypoxia exposure-induced atherosclerosis: a brief review
Q35086929Chronic intermittent hypoxia increases blood pressure and expression of FosB/DeltaFosB in central autonomic regions
Q51764236Chronic intermittent hypoxia induces hormonal and male sexual behavioral changes: Hypoxia as an advancer of aging.
Q33679761Chronic intermittent hypoxia induces oxidative stress and inflammation in brain regions associated with early-stage neurodegeneration
Q60301442Chronic intermittent hypoxia-mediated renal sympathetic nerve activation in hypertension and cardiovascular disease
Q38101728Circulating adhesion molecules in obstructive sleep apnea and cardiovascular disease
Q39413926Circulating exosomes in obstructive sleep apnea as phenotypic biomarkers and mechanistic messengers of end-organ morbidity
Q30389382Co-activation of μ- and δ-opioid receptors elicits tolerance to morphine-induced ventilatory depression via generation of peroxynitrite
Q36791654Cognition and biomarkers of oxidative stress in obstructive sleep apnea
Q33806219Combination of erythropoietin and sildenafil can effectively attenuate hypoxia-induced pulmonary hypertension in mice
Q48278669Combined effect of obstructive sleep apnea and age on daytime blood pressure
Q38111142Common mechanisms of compensatory respiratory plasticity in spinal neurological disorders
Q36808834Comorbidities Associated with Obstructive Sleep Apnea: a Retrospective Study
Q36603628Comparative evaluation of craniofacial anthropometric measurements in Indian adult patients with and without obstructive sleep apnea: A pilot study
Q89866358Comparison between blood pressure during obstructive respiratory events in REM and NREM sleep using pulse transit time
Q37095489Comparison of Sleep Disorders between Real and Simulated 3,450-m Altitude
Q92795879Comparison of upper airway measurement by lateral cephalogram in upright position and CBCT in supine position
Q48148793Complex sleep apnea
Q37964622Computational models for the study of heart-lung interactions in mammals
Q43457674Consecutive transcranial magnetic stimulation twitches reduce flow limitation during sleep in apnoeic patients
Q47364059Consequences of maternal omega-3 polyunsaturated fatty acid supplementation on respiratory function in rat pups.
Q58710225Continuous positive airway pressure effect on visual acuity in patients with type 2 diabetes and obstructive sleep apnoea: a multicentre randomised controlled trial
Q90533496Contribution of Oxidative Stress and Inflammation to the Neurogenic Hypertension Induced by Intermittent Hypoxia
Q24634619Control of sleep and wakefulness
Q44747950Correlation between inflammatory markers of atherosclerosis and carotid intima-media thickness in Obstructive Sleep Apnea.
Q53681657Correlation between metabolic syndrome and sleep apnea.
Q42723886Correlation of obstructive sleep apnea hypopnea syndrome with metabolic syndrome in snorers
Q42217838Critical Role of Endoplasmic Reticulum Stress in Chronic Intermittent Hypoxia-Induced Deficits in Synaptic Plasticity and Long-Term Memory
Q48093832CrossTalk opposing view: Loop gain is not a consequence of obstructive sleep apnoea
Q48173273CrossTalk proposal: the human upper airway does behave like a Starling resistor during sleep
Q35682939Crossed motor innervation of the base of human tongue
Q47943982Crucial Role of the Carotid Body Chemoreceptors on the Development of High Arterial Blood Pressure During Chronic Intermittent Hypoxia
Q58700894Culturally tailored, peer-based sleep health education and social support to increase obstructive sleep apnea assessment and treatment adherence among a community sample of blacks: study protocol for a randomized controlled trial
Q46259726DNA methylation in the central and efferent limbs of the chemo reflex requires carotid body neural activity
Q38080761Death by a thousand cuts in Alzheimer's disease: hypoxia--the prodrome
Q35478501Decreased Regional Cerebral Perfusion in Moderate-Severe Obstructive Sleep Apnoea during Wakefulness.
Q64245857Desmin and dystrophin abnormalities in upper airway muscles of snorers and patients with sleep apnea
Q42363825Development of a Clinical Pathway and Technical Aspects of Upper Airway Stimulation Therapy for Obstructive Sleep Apnea
Q37060214Development of autonomic dysfunction with intermittent hypoxia in a lean murine model
Q37227528Developmental changes in the morphology of mouse hypoglossal motor neurons
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Q47562447Diagnostic accuracy of level IV portable sleep monitors versus polysomnography for obstructive sleep apnea: a systematic review and meta-analysis.
Q47682789Diagnostic performance of cheeks appearance in sleep apnea
Q36999754Diaphragm muscle remodeling in a rat model of chronic intermittent hypoxia
Q35142653Dichotomous effects of chronic intermittent hypoxia on focal cerebral ischemic injury
Q39403276Diet and exercise in the management of obstructive sleep apnoea and cardiovascular disease risk
Q37094674Different Craniofacial Characteristics Predict Upper Airway Collapsibility in Japanese-Brazilian and White Men.
Q90601927Differential expression of immune markers in the patients with obstructive sleep apnea/hypopnea syndrome
Q47905401Does experimental paradoxical sleep deprivation (EPSD) is an appropriate model for evaluation of cardiovascular complications of obstructive sleep apnea?
Q34235233Does race-ethnicity moderate the relationship between CPAP adherence and functional outcomes of sleep in US veterans with obstructive sleep apnea syndrome?
Q40157811Downregulation of uncoupling protein-1 mRNA expression and hypoadiponectinemia in a mouse model of sleep apnea.
Q40021922Drug trials for obstructive sleep apnea.
Q38602645Drug-induced sedation endoscopy versus clinical exploration for the diagnosis of severe upper airway obstruction in OSAHS patients
Q59340090ENT and mucopolysaccharidoses
Q47935780Echocardiographic findings and plasma endothelin-1 levels in obese patients with and without obstructive sleep apnea
Q55256781Effect of Acute, Subacute, and Repeated Exposure to High Altitude (5050 m) on Psychomotor Vigilance.
Q55516492Effect of Gender on Chronic Intermittent Hypoxic Fosb Expression in Cardiorespiratory-Related Brain Structures in Mice.
Q53408826Effect of Rapid Eye Movement Sleep Behavior Disorder on Obstructive Sleep Apnea Severity and Cognition of Parkinson's Disease Patients.
Q38886533Effect of Sleeping Position on Upper Airway Patency in Obstructive Sleep Apnea Is Determined by the Pharyngeal Structure Causing Collapse
Q35951157Effect of chronic intermittent hypoxia on noradrenergic activation of hypoglossal motoneurons
Q35544844Effect of diuretics and sodium-restricted diet on sleep apnea severity: study protocol for a randomized controlled trial
Q47728243Effect of modern surgical treatment on the inflammatory/anti-inflammatory balance in patients with obstructive sleep apnoea
Q38260517Effect of sedative-hypnotics, anesthetics and analgesics on sleep architecture in obstructive sleep apnea
Q42206349Effect of sleep on breathing - Why recurrent apneas are only seen during sleep
Q41623574Effect of transoral endoscopic adenoidectomy on peripheral blood T-lymphocyte subsets in children with obstructive sleep apnea-hypopnea syndrome and its treatment strategy
Q51730788Effects of Bedroom Environmental Conditions on the Severity of Obstructive Sleep Apnea.
Q47682676Effects of Cannabinoid Agonists and Antagonists on Sleep and Breathing in Sprague-Dawley Rats
Q57819508Effects of Increased Pharyngeal Tissue Mass Due to Fluid Accumulation in the Neck on the Acoustic Features of Snoring Sounds in Men
Q30368951Effects of Obstructive Sleep Apnea and Obesity on Cardiac Remodeling: The Wisconsin Sleep Cohort Study.
Q64109656Effects of an Adenotonsillectomy on the Cognitive and Behavioural Function of Children Who Snore: A naturalistic observational study
Q37518432Effects of chronic sleep fragmentation on wake-active neurons and the hypercapnic arousal response
Q48021825Effects of dorsomedial medullary 5-HT2 receptor antagonism on initial ventilatory airway responses to hypercapnic hypoxia in mice
Q38110759Effects of gas exchange on acid-base balance.
Q37505948Effects of inhaled fluticasone on upper airway during sleep and wakefulness in asthma: a pilot study
Q35222160Effects of orexin 2 receptor activation on apnea in the C57BL/6J mouse
Q47811378Effects of repetitive transcranial magnetic stimulation of upper airway muscles during sleep in obstructive sleep apnea patients
Q37054675Effects of stabilizing or increasing respiratory motor outputs on obstructive sleep apnea
Q90177552Efficacy and adherence of auto-CPAP therapy in patients with obstructive sleep apnea: a prospective study
Q38668431Electrical stimulation for the treatment of obstructive sleep apnoea: a review of the evidence
Q52728801Elevations in neutrophils with obstructive sleep apnea: The Multi-Ethnic Study of Atherosclerosis (MESA).
Q34300711Endothelin 1-dependent neurovascular dysfunction in chronic intermittent hypoxia
Q34608364Enhanced carotid body chemosensory activity and the cardiovascular alterations induced by intermittent hypoxia
Q30366078Enhanced non-eupneic breathing following hypoxic, hypercapnic or hypoxic-hypercapnic gas challenges in conscious mice.
Q40177344Environmental Enrichment Prevent the Juvenile Hypoxia-Induced Developmental Loss of Parvalbumin-Immunoreactive Cells in the Prefrontal Cortex and Neurobehavioral Alterations Through Inhibition of NADPH Oxidase-2-Derived Oxidative Stress
Q47929499Enzalutamide and sleep apnea: an emerging central nervous system side-effect?
Q35832711Epigenomic profiling in visceral white adipose tissue of offspring of mice exposed to late gestational sleep fragmentation.
Q48049049Erythropoietin does not have effects on the ventilatory and pulmonary vascular response to acute hypoxia in men and women
Q30419870Etiopathogenetic mechanisms of pulmonary hypertension in sleep-related breathing disorders
Q98465633Evaluation of Serum and Plasma Interleukin-6 Levels in Obstructive Sleep Apnea Syndrome: A Meta-Analysis and Meta-Regression
Q51730785Evaluation of a Trial Period With a Sleep Position Trainer in Patients With Positional Sleep Apnea.
Q41090861Evaluation of the predictive value of red blood cell distribution width for onset of cerebral infarction in the patients with obstructive sleep apnea hypopnea syndrome
Q39173365Evening and morning peroxiredoxin-2 redox/oligomeric state changes in obstructive sleep apnea red blood cells: Correlation with polysomnographic and metabolic parameters
Q35677223Exogenous growth hormone attenuates cognitive deficits induced by intermittent hypoxia in rats
Q34575701Experimental pain and opioid analgesia in volunteers at high risk for obstructive sleep apnea
Q34663312Experimental protocols and preparations to study respiratory long term facilitation
Q34062951Exposure of mice to chronic hypoxia attenuates pulmonary arterial contractile responses to acute hypoxia by increases in extracellular hydrogen peroxide
Q45132502Factors influencing the response of psychological symptoms to continuous positive airway pressure therapy
Q54116553Fasudil improves endothelial dysfunction in rats exposed to chronic intermittent hypoxia through RhoA/ROCK/NFATc3 pathway.
Q48243276Filling in the pieces of the sleep apnea-hypertension puzzle
Q42604098Fingerprinting-based metabolomic approach with LC-MS to sleep apnea and hypopnea syndrome: a pilot study.
Q35023591Frequent periodic leg movement during sleep is an unrecognized risk factor for progression of atrial fibrillation
Q47942661Functional outcome of tongue motions with selective hypoglossal nerve stimulation in patients with obstructive sleep apnea
Q26827948Future of Sleep-Disordered Breathing Therapy Using a Mechanistic Approach
Q37364745Growth hormone releasing hormone (GHRH) signaling modulates intermittent hypoxia-induced oxidative stress and cognitive deficits in mouse
Q55380515Guinea Pig as a Model to Study the Carotid Body Mediated Chronic Intermittent Hypoxia Effects.
Q46487608Hepatic Cyp1a2 Expression Reduction during Inflammation Elicited in a Rat Model of Intermittent Hypoxia
Q35130266Hepatic oxidative stress in an animal model of sleep apnoea: effects of different duration of exposure
Q36234613Hepatocyte Hypoxia Inducible Factor-1 Mediates the Development of Liver Fibrosis in a Mouse Model of Nonalcoholic Fatty Liver Disease
Q37678352High intensity aerobic exercise training improves chronic intermittent hypoxia-induced insulin resistance without basal autophagy modulation
Q46476087High risk for sleep apnea in the Berlin questionnaire and coronary artery disease
Q36115297Human apolipoprotein E4 targeted replacement in mice reveals increased susceptibility to sleep disruption and intermittent hypoxia
Q35817898Humans In Hypoxia: A Conspiracy Of Maladaptation?!
Q33714452Hypercapnia is a key correlate of EEG activation and daytime sleepiness in hypercapnic sleep disordered breathing patients
Q47888286Hypercapnia is more important than hypoxia in the neuro-outcomes of sleep-disordered breathing
Q50148800Hypoglossal Nerve Stimulation in a Pre-Clinical Anesthetized Rabbit Model Relevant to OSA.
Q47799588Hypoxia-induced microRNA-26b inhibition contributes to hypoxic pulmonary hypertension via CTGF.
Q30415118Hypoxia-induced ventilatory responses in conscious mice: gender differences in ventilatory roll-off and facilitation
Q26768865Hypoxia: The Force that Drives Chronic Kidney Disease
Q57099542Hypoxic pulmonary vasoconstriction
Q41892767Identification of a pharmacological target for genioglossus reactivation throughout sleep
Q33705228Impact of Compression Stockings vs. Continuous Positive Airway Pressure on Overnight Fluid Shift and Obstructive Sleep Apnea among Patients on Hemodialysis
Q38009039Impact of breath holding on cardiovascular respiratory and cerebrovascular health
Q38821538Impact of obstructive sleep apnoea and intermittent hypoxia on cardiovascular and cerebrovascular regulation.
Q48009102Impact of rapid ascent to high altitude on sleep
Q35787447Impact of repeated daily exposure to intermittent hypoxia and mild sustained hypercapnia on apnea severity
Q36850754Inactivity-induced phrenic and hypoglossal motor facilitation are differentially expressed following intermittent vs. sustained neural apnea
Q92341358Increase in the frequency of obstructive sleep apnea in elderly people
Q36369678Increased Muscle Sympathetic Nerve Activity and Impaired Executive Performance Capacity in Obstructive Sleep Apnea.
Q33723873Increased arterial stiffness in obstructive sleep apnea: a systematic review.
Q34615048Increased cardio-respiratory coupling evoked by slow deep breathing can persist in normal humans
Q35143486Increased cerebrovascular sensitivity to endothelin-1 in a rat model of obstructive sleep apnea: a role for endothelin receptor B
Q36828589Increased sympathetic and decreased parasympathetic cardiac tone in patients with sleep related alveolar hypoventilation
Q41007166Independent associations between arterial bicarbonate, apnea severity and hypertension in obstructive sleep apnea
Q48349535Indomethacin-induced impairment of regional cerebrovascular reactivity: implications for respiratory control
Q38293699Inflammation and oxidative stress during intermittent hypoxia: the impact on chemoreception.
Q35137720Inflammation in sleep apnea: an update.
Q47689143Inflammatory and oxidative stress‑associated factors in chronic intermittent hypoxia in Chinese patients, rats, lymphocytes and endotheliocytes
Q45766091Influence of sleep apnea severity on blood pressure variability of patients with hypertension
Q37736610Innate immunity modulation in the duodenal mucosa induced by REM sleep deprivation during infection with Trichinella spirallis
Q47649290Insulin sensitivity, leptin, adiponectin, resistin, and testosterone in adult male and female rats after maternal-neonatal separation and environmental stress
Q35976931Integrative miRNA-mRNA profiling of adipose tissue unravels transcriptional circuits induced by sleep fragmentation
Q89673421Intermittent Hypoxia Augments Pulmonary Vasoconstrictor Reactivity through PKCβ/Mitochondrial Oxidant Signaling
Q64251883Intermittent Hypoxia Up-Regulates Gene Expressions of in Enteroendocrine Cells
Q36424244Intermittent Hypoxia-Induced Carotid Body Chemosensory Potentiation and Hypertension Are Critically Dependent on Peroxynitrite Formation
Q34840423Intermittent hypoxemia and OSA: implications for comorbidities
Q44011217Intermittent hypoxia and diet-induced obesity: effects on oxidative status, sympathetic tone, plasma glucose and insulin levels, and arterial pressure.
Q47638275Intermittent hypoxia causes histological kidney damage and increases growth factor expression in a mouse model of obstructive sleep apnea
Q37092265Intermittent hypoxia from obstructive sleep apnea may cause neuronal impairment and dysfunction in central nervous system: the potential roles played by microglia
Q34197603Intermittent hypoxia mobilizes bone marrow-derived very small embryonic-like stem cells and activates developmental transcriptional programs in mice
Q94671516Intermittent hypoxia modulates redox homeostasis, lipid metabolism associated inflammatory processes and redox post-translational modifications: Benefits at high altitude
Q47767706Intermittent hypoxia revisited: a promising non-pharmaceutical strategy to reduce cardio-metabolic risk factors?
Q35055945Intermittent hypoxia-induced sensitization of central chemoreceptors contributes to sympathetic nerve activity during late expiration in rats
Q26824915Intermittent hypoxia: a low-risk research tool with therapeutic value in humans
Q42328188Interventional Drug-Induced Sleep Endoscopy: A Novel Technique to Guide Surgical Planning for Obstructive Sleep Apnea
Q38832964Intracranial mechanisms for preserving brain blood flow in health and disease
Q36770920Intradialytic Hypoxemia and Clinical Outcomes in Patients on Hemodialysis.
Q33672788Is C-reactive protein a marker of obstructive sleep apnea?: A meta-analysis
Q35624212Is obstructive sleep apnea associated with cortisol levels? A systematic review of the research evidence.
Q36095782It takes a mouth to eat and a nose to breathe: abnormal oral respiration affects neonates' oral competence and systemic adaptation
Q47774432Late gestational intermittent hypoxia induces metabolic and epigenetic changes in male adult offspring mice
Q47685523Left ventricular strain rate is reduced during voluntary apnea in healthy humans.
Q43746033Leptin signaling in the nucleus of the solitary tract alters the cardiovascular responses to activation of the chemoreceptor reflex
Q35212608Leukotriene B4 receptor-1 mediates intermittent hypoxia-induced atherogenesis
Q33563733Lingual muscle activity across sleep-wake States in rats with surgically altered upper airway
Q36203008Lower hypoxic ventilatory response in smokers compared to non-smokers during abstinence from cigarettes
Q48034119MEMBRANE PROGESTERONE RECEPTOR β, BUT NOT α, IN DORSAL BRAINSTEM ESTABLISHES SEX-SPECIFIC CHEMOREFLEX RESPONSES AND REDUCES APNEA FREQUENCY IN ADULT MICE.
Q92081261Magnitude and Determinants of Patients at Risk of Developing Obstructive Sleep Apnea in a Non-Communicable Disease Clinic
Q36490066Making sense of oxidative stress in obstructive sleep apnea: mediator or distracter?
Q99617415Managements for Obstructive Sleep Apnea in Adults: Review
Q43944859Measurement of dyspnea in patients with obstructive sleep apnea
Q47994056Mechanical effects of repetitive transcranial magnetic stimulation of upper airway muscles in awake obstructive sleep apnoea subjects
Q38165141Mechanical properties of respiratory muscles
Q30449453Mechanical properties of the upper airway
Q47976663Melatonin prevents hyperglycemia in a model of sleep apnea
Q34340704Meta-analysis: continuous positive airway pressure improves insulin resistance in patients with sleep apnea without diabetes
Q90524853Metabolomic and lipidomic profile in men with obstructive sleep apnoea: implications for diagnosis and biomarkers of cardiovascular risk
Q57050031MiRNA expression profiles in healthy OSAHS and OSAHS with arterial hypertension: potential diagnostic and early warning markers
Q91803429MicroRNA expression profile is altered in the upper airway skeletal muscle tissue of patients with obstructive sleep apnea-hypopnea syndrome
Q47875351Morning cortisol levels and glucose metabolism parameters in moderate and severe obstructive sleep apnea patients.
Q30411852Morphine has latent deleterious effects on the ventilatory responses to a hypoxic challenge
Q30411856Morphine has latent deleterious effects on the ventilatory responses to a hypoxic-hypercapnic challenge
Q36282468Multimodality therapy for sleep apnea syndromes
Q48420421Muscarinic acetylcholine receptors enhance neonatal mouse hypoglossal motoneuron excitability in vitro
Q37284845Neonatal Maternal Separation Augments Carotid Body Response to Hypoxia in Adult Males but Not Female Rats
Q47600668Neonatal maternal separation opposes the facilitatory effect of castration on the respiratory response to hypercapnia of the adult male rat: Evidence for the involvement of the medial amygdala
Q47996462Neonatal stress affects the aging trajectory of female rats on the endocrine, temperature, and ventilatory responses to hypoxia
Q48182180Neonatal stress augments the hypoxic chemoreflex of adult male rats by increasing AMPA receptor-mediated modulation
Q28078657Neural Control of Blood Pressure in Chronic Intermittent Hypoxia
Q37591858Neural Control of the Upper Airway: Respiratory and State-Dependent Mechanisms
Q38111288Neural control of the upper airway: integrative physiological mechanisms and relevance for sleep disordered breathing
Q58754382Neuroanatomical Basis of State-Dependent Activity of Upper Airway Muscles
Q38363900Neurogenic changes in the upper airway of obstructive sleep apnoea
Q36382223Neurogenic mechanisms underlying the rapid onset of sympathetic responses to intermittent hypoxia.
Q38111735Neuronal control of breathing: sex and stress hormones.
Q64914170Neurotrophic factor BDNF is upregulated in soft palate muscles of snorers and sleep apnea patients.
Q89635060Non-alcoholic fatty liver disease among patients with sleep disorders: a Nationwide study of Taiwan
Q36189704Nonlinear Dynamics Forecasting of Obstructive Sleep Apnea Onsets.
Q35957627Novel Approach to Simulate Sleep Apnea Patients for Evaluating Positive Pressure Therapy Devices
Q35541483NuMoM2b Sleep-Disordered Breathing study: objectives and methods
Q92692917OBEDIS Core Variables Project: European Expert Guidelines on a Minimal Core Set of Variables to Include in Randomized, Controlled Clinical Trials of Obesity Interventions
Q37961776Obesity hypoventilation syndrome: from sleep-disordered breathing to systemic comorbidities and the need to offer combined treatment strategies.
Q60624588Obesity, obstructive sleep apnea and type 2 diabetes mellitus: Epidemiology and pathophysiologic insights
Q48034168Observation following tonsillectomy may be inadequate due to silent death
Q37658755Obstructive Sleep Apnea and Lipid Abnormalities
Q34729134Obstructive Sleep Apnea and Multiple Anthropometric Indices of General Obesity and Abdominal Obesity among Young Adults.
Q40160441Obstructive Sleep Apnea and Subclinical Interstitial Lung Disease in MESA.
Q38878249Obstructive Sleep Apnea and Vascular Diseases.
Q36764419Obstructive Sleep Apnea in Patients with Branch Retinal Vein Occlusion: A Preliminary Study
Q36368997Obstructive Sleep Apnea, Hypertension, and Their Additive Effects on Atherosclerosis
Q93032893Obstructive Sleep Apnea, Hypoxia, and Nonalcoholic Fatty Liver Disease
Q38736599Obstructive Sleep Apnea-Induced Hypertension: Role of the Gut Microbiota
Q88301765Obstructive sleep apnea and effects of continuous positive airway pressure on triglyceride-rich lipoprotein metabolism
Q37530601Obstructive sleep apnea and neurocognitive performance: the role of cortisol
Q64983915Obstructive sleep apnea as an independent predictor of postoperative delirium and pain: protocol for an observational study of a surgical cohort.
Q57788725Obstructive sleep apnea in patients surviving acute hypercapnic respiratory failure is best predicted by static hyperinflation
Q33983903Obstructive sleep apnea in pregnancy: reliability of prevalence and prediction estimates
Q30447694Obstructive sleep apnea in young lean men: impact on insulin sensitivity and secretion
Q48330682Obstructive sleep apnea may increase the risk of stroke in AF patients: Refining the CHADS2 score
Q43568388Obstructive sleep apnea pharmacotherapy: one step closer
Q36722885Obstructive sleep apnea related to rapid-eye-movement or non-rapid-eye-movement sleep: comparison of demographic, anthropometric, and polysomnographic features
Q38179027Obstructive sleep apnea syndrome and chronic kidney disease: a new cardiorenal risk factor
Q33988159Obstructive sleep apnea syndrome is associated with deficits in verbal but not visual memory
Q28084261Obstructive sleep apnea, pain, and opioids: is the riddle solved?
Q47973595Obstructive sleep apnoea should be deemed a cardiovascular disease.
Q89216818Obstructive sleep apnoea syndrome
Q26785989Obstructive sleep apnoea syndrome and its management
Q28081330On the cutting edge of obstructive sleep apnoea: where next?
Q30414026Optogenetic stimulation of c1 and retrotrapezoid nucleus neurons causes sleep state-dependent cardiorespiratory stimulation and arousal in rats
Q39194858Oral appliance in sleep apnea treatment: respiratory and clinical effects and long-term adherence
Q47669203Oral appliance treatment outcome can be predicted by continuous positive airway pressure in moderate to severe obstructive sleep apnea
Q37114229Origins of and implementation concepts for upper airway stimulation therapy for obstructive sleep apnea
Q48221600Overnight heart rate variability in patients with obstructive sleep apnoea: a time and frequency domain study.
Q38695841Oxygen sensing by the carotid body: mechanisms and role in adaptation to hypoxia.
Q37169927P2Y1 receptors expressed by C1 neurons determine peripheral chemoreceptor modulation of breathing, sympathetic activity, and blood pressure
Q64265091Palatal anatomy for sleep apnea surgery
Q47772821Palatoglossus coupling in selective upper airway stimulation
Q27025575Pathogenic roles of the carotid body inflammation in sleep apnea
Q36053044Pathological effects of obstructive apneas during the sleep cycle in an animal model of cerebral small vessel disease
Q38219952Pathophysiology of human ventilatory control
Q37840296Patterns of unexpected in-hospital deaths: a root cause analysis
Q48004029Periodic breathing in healthy humans at exercise in hypoxia.
Q48260732Pharyngeal neuropathy in obstructive sleep apnea: where are we going?
Q30241786Phenotypes in obstructive sleep apnea: A definition, examples and evolution of approaches
Q48298175Phenotyping interindividual variability in obstructive sleep apnoea response to temazepam using ventilatory chemoreflexes during wakefulness
Q30429878Photostimulation of Phox2b medullary neurons activates cardiorespiratory function in conscious rats
Q35882854Physiological and pathophysiological interactions between the respiratory central pattern generator and the sympathetic nervous system
Q26829148Physiology in medicine: obstructive sleep apnea pathogenesis and treatment--considerations beyond airway anatomy
Q36303952Piecing together phenotypes of brain injury and dysfunction in obstructive sleep apnea
Q38908062Plasticity in respiratory motor neurons in response to reduced synaptic inputs: A form of homeostatic plasticity in respiratory control?
Q47840395Polysomnography findings in spinocerebellar ataxia type 6.
Q60921514Post-approval upper airway stimulation predictors of treatment effectiveness in the ADHERE registry
Q95924542Postictal stertor: Associations with focal and bilateral seizure types
Q90344503Postoperative complications with neuromuscular blocking drugs and/or reversal agents in obstructive sleep apnea patients: a systematic review
Q90625006Potential Contribution of Carotid Body-Induced Sympathetic and Renin-Angiotensin System Overflow to Pulmonary Hypertension in Intermittent Hypoxia
Q93197937Potential Role of mRNAs and LncRNAs in Chronic Intermittent Hypoxia Exposure-Aggravated Atherosclerosis
Q38264989Predictors of successful completion of diagnostic home sleep testing in patients with chronic kidney disease.
Q37120767Preeclampsia and Sleep-Disordered Breathing: A Case-Control Study
Q89172307Preperitoneal Bupivacaine Infiltration Reduces Postoperative Opioid Consumption, Acute Pain, and Chronic Postsurgical Pain After Bariatric Surgery: a Randomized Controlled Trial
Q33588505Prevalence and risk factors of obstructive sleep apnea syndrome in a Saudi Arabian population
Q98224625Prevalence of Obstructive Sleep Apnea in Patients With Diabetic Foot Ulcers
Q47689125Prevalence of sleep apnea and cardiovascular risk factors in patients with hypertension in a day hospital model
Q47733089Psoriasis is associated with risk of obstructive sleep apnea independently from metabolic parameters and other comorbidities: a large hospital-based case-control study.
Q36473686Pulmonary C-fiber activation attenuates respiratory-related tongue movements
Q51702895Pulmonary vascular tone is dependent on the central modulation of sympathetic nerve activity following chronic intermittent hypoxia.
Q35085818Purinergic signalling contributes to chemoreception in the retrotrapezoid nucleus but not the nucleus of the solitary tract or medullary raphe
Q38034108Quintessential risk factors: their role in promoting cognitive dysfunction and Alzheimer's disease
Q47682307RELATIONSHIP BETWEEN OBSTRUCTIVE SLEEP APNEA AND THE PRESENCE AND SEVERITY OF DIABETIC RETINOPATHY.
Q33679756Rapid-eye-movement sleep-predominant central sleep apnea relieved by positive airway pressure: a case report
Q35562952Rats subjected to chronic-intermittent hypoxia have increased density of noradrenergic terminals in the trigeminal sensory and motor nuclei
Q48251655Re: Effects of leptin and obesity on the upper airway function by Polotsky et al.
Q52730995Reactive oxygen radicals and gaseous transmitters in carotid body activation by intermittent hypoxia.
Q36770711Reduced c-Fos expression in medullary catecholaminergic neurons in rats 20 h after exposure to chronic intermittent hypoxia
Q28391062Reducing health disparities: the role of sleep deficiency and sleep disorders
Q37479198Regional cerebral blood flow alterations in obstructive sleep apnea
Q39608855Regional hypoxic cerebral vasodilation facilitated by diameter changes primarily in anterior versus posterior circulation
Q37510477Regional reductions in sleep electroencephalography power in obstructive sleep apnea: a high-density EEG study
Q30301264Regulation of breathing and autonomic outflows by chemoreceptors
Q90311366Relationship Between Intermittent Hypoxia and Type 2 Diabetes in Sleep Apnea Syndrome
Q92650087Relationship Between Sleep Apnea and Coronary Artery Calcium in Patients With Ischemic Stroke
Q92857283Relationship between sleep and obesity among U.S. and South Korean college students
Q38019769Relationships between vascular oxygen sensing mechanisms and hypertensive disease processes
Q47676615Remote consulting with telemonitoring of continuous positive airway pressure usage data for the routine review of people with obstructive sleep apnoea hypopnoea syndrome: A systematic review.
Q50334203Reproducibility of hypercapnic ventilatory response measurements with steady-state and rebreathing methods.
Q37811998Resistant hypertension and sleep apnea: pathophysiologic insights and strategic management
Q47657170Resolution of Symptomatic Obstructive Sleep Apnea Not Impacted by Preoperative Body Mass Index, Choice of Operation Between Sleeve Gastrectomy and Roux-en-Y Gastric Bypass Surgery, or Severity.
Q30457547Respiratory and sleep disorders in mucopolysaccharidosis
Q45030495Respiratory modulation of human autonomic function on Earth.
Q47762734Resting cerebral blood flow alteration in severe obstructive sleep apnoea: an arterial spin labelling perfusion fMRI study
Q45751138Resting, night-time, and 24 h heart rate as markers of cardiovascular risk in middle-aged and elderly men and women with no apparent heart disease
Q48886201Restructuring of sleep and reversal of REM-induced supraspinal hypotonia of respiratory muscles following bilateral phrenicotomy
Q90537703Risk factors for the development of idiopathic pulmonary fibrosis: A review
Q37254188Risk of obstructive sleep apnea, excessive daytime sleepiness and depressive symptoms in a Nigerian elderly population
Q39268819Role of Carotid Body in Intermittent Hypoxia-Related Hypertension
Q47781593Role of angiotensin-converting enzyme 1 within the median preoptic nucleus following chronic intermittent hypoxia
Q33976322Role of chemoreception in cardiorespiratory acclimatization to, and deacclimatization from, hypoxia
Q30393764Role of nitric oxide-containing factors in the ventilatory and cardiovascular responses elicited by hypoxic challenge in isoflurane-anesthetized rats
Q35880067Role of the Gut Microbiome in Obstructive Sleep Apnea-Induced Hypertension
Q47918714Roles of interleukin (IL)-6 gene polymorphisms, serum IL-6 levels, and treatment in obstructive sleep apnea: a meta-analysis
Q91257407Sagittal Measurement of Tongue Movement During Respiration: Comparison Between Ultrasonography and Magnetic Resonance Imaging
Q62007536Schlafbezogene Atmungsstörungen
Q89024739Sciatic nerve stimulation and its effects on upper airway resistance in the anesthetized rabbit model relevant to sleep apnea
Q45330173Screening for obstructive sleep apnea in veterans with ischemic heart disease using a computer-based clinical decision-support system
Q89581132Severe desaturations increase PVT-based median reaction time and number of lapses in OSA patients
Q77790350Severe obstructive sleep apnea is associated with alterations in the nasal microbiome and an increase in inflammation
Q93092764Severity of Desaturations Reflects OSA-Related Daytime Sleepiness Better Than AHI
Q47652448Sex differences in sleep apnea and comorbid neurodegenerative diseases.
Q37631992Should the diagnosis and management of OSA move into general practice?
Q36974940Signalment, clinical presentation, concurrent diseases, and diagnostic findings in 28 dogs with dynamic pharyngeal collapse (2008-2013).
Q59328947Silencing of Hypoglossal Motoneurons Leads to Sleep Disordered Breathing in Lean Mice
Q36443187Simulating sleep apnea by exposure to intermittent hypoxia induces inflammation in the lung and liver
Q54936459Simulation of the upper airways in patients with obstructive sleep apnea and nasal obstruction: A novel finite element method.
Q38901960Simultaneous recording of ultrasound and polysomnography during natural sleep in patients with obstructive sleep apnea: a pilot study.
Q42353190Sleep Apnea in Familial Dysautonomia: A Reflection of Apnea Pathogenesis
Q38756440Sleep Apnea: Types, Mechanisms, and Clinical Cardiovascular Consequences.
Q47645255Sleep apnea and pesticide exposure in a study of US farmers
Q37676196Sleep apnea and risk of pneumonia: a nationwide population-based study
Q33943666Sleep apnea in fragile X premutation carriers with and without FXTAS.
Q38754350Sleep apnea in total joint arthroplasty patients and the role for cardiac biomarkers for risk stratification: an exploration of feasibility.
Q48291170Sleep apnea is a stronger predictor for coronary heart disease than traditional risk factors
Q39519512Sleep apnea is associated with an increased risk of mood disorders: a population-based cohort study
Q38558161Sleep at high altitude: guesses and facts
Q41443686Sleep disordered breathing and the risk of psoriasis among US women.
Q28596790Sleep disordered breathing: is it different for females?
Q40957500Sleep disorders in pregnancy and their association with pregnancy outcomes: a prospective observational study
Q43123404Sleep disorders, public health, and public safety.
Q39369116Sleep disturbance and sleep-disordered breathing in hemodialysis patients
Q48302890Sleep in patients with large pleural effusion: impact of thoracentesis
Q37103429Sleep symptoms, race/ethnicity, and socioeconomic position.
Q87659769Sleep-Disordered Breathing During Congestive Heart Failure: To Intervene or Not to Intervene?
Q34276124Sleep-disordered breathing and cancer mortality: results from the Wisconsin Sleep Cohort Study
Q56344132Sleep-disordered breathing and electrocardiographic QRS-T angle: The MESA study
Q37193708Sleep-disordered breathing and gestational diabetes mellitus: a meta-analysis of 9,795 participants enrolled in epidemiological observational studies
Q95261292Sleep-disordered breathing in pregnancy: a developmental origin of offspring obesity?
Q48102128Sleep-disordered breathing-related neurocognitive impairment, time to think beyond hypoxia and sleep fragmentation?
Q37185178Sleep-related changes in autonomic control in obstructive sleep apnea: a model-based perspective
Q63516839Sloshing and slamming oscillations in a collapsible channel flow
Q37219893Snoring, daytime sleepiness, and incident cardiovascular disease in the health, aging, and body composition study
Q33607080Specific branches of hypoglossal nerve to genioglossus muscle as a potential target of selective neurostimulation in obstructive sleep apnea: anatomical and morphometric study.
Q26858790State-dependent and reflex drives to the upper airway: basic physiology with clinical implications
Q34305377Sustained hyperoxia stabilizes breathing in healthy individuals during NREM sleep
Q38863582Symptomless Multi-Variable Apnea Prediction Index Assesses Obstructive Sleep Apnea Risk and Adverse Outcomes in Elective Surgery.
Q92431564THE ROLE OF CORTISOL IN NEUROCOGNITIVE PERFORMANCE IN OBSTRUCTIVE SLEEP APNEA PATIENTS
Q26771548Tailored treatment strategies for obstructive sleep apnea
Q37653173Telemedicine-based approach for obstructive sleep apnea management: building evidence.
Q48121063Testosterone potentiates the hypoxic ventilatory response of adult male rats subjected to neonatal stress.
Q82459833Testosterone restores respiratory long term facilitation in old male rats by an aromatase-dependent mechanism
Q58799135The Bidirectional Relationship Between Obstructive Sleep Apnea and Metabolic Disease
Q34288892The Impact of Obstructive Sleep Apnea on Chronic Kidney Disease
Q93186026The Purinome and the preBötzinger Complex - A Ménage of Unexplored Mechanisms That May Modulate/Shape the Hypoxic Ventilatory Response
Q33692680The Relationship between High Risk for Obstructive Sleep Apnea and General and Central Obesity: Findings from a Sample of Chilean College Students
Q41665400The Role of the Autonomic Nervous System in the Pathophysiology of Obesity.
Q92670282The Sleep-Immune Crosstalk in Health and Disease
Q39043956The Triad of Sleep Apnea, Hypertension, and Chronic Kidney Disease: A Spectrum of Common Pathology
Q36764166The Young Everest Study: preliminary report of changes in sleep and cerebral blood flow velocity during slow ascent to altitude in unacclimatised children.
Q36639762The association between atrial fibrillation and stroke in patients with obstructive sleep apnea: a population-based case-control study
Q36287773The association of kidney function with repetitive breath-hold diving activities of female divers from Korea, Haenyeo
Q34992979The correlation between red blood cell distribution width levels with the severity of obstructive sleep apnea and carotid intima media thickness.
Q47811332The effect of CPAP treatment on venous lactate and arterial blood gas among obstructive sleep apnea syndrome patients
Q36422672The effect of leptin replacement on sleep-disordered breathing in the leptin-deficient ob/ob mouse
Q35888424The effect of tongue exercise on serotonergic input to the hypoglossal nucleus in young and old rats
Q30428971The efficacy of antihypertensive drugs in chronic intermittent hypoxia conditions.
Q34132243The hypoxic ventilatory response and ventilatory long-term facilitation are altered by time of day and repeated daily exposure to intermittent hypoxia
Q36531006The impact of arousal state, sex, and sleep apnea on the magnitude of progressive augmentation and ventilatory long-term facilitation
Q38077649The impact of diet and lifestyle management strategies for obstructive sleep apnoea in adults: a systematic review and meta-analysis of randomised controlled trials
Q36089133The importance of obstructive sleep apnoea and hypopnea pathophysiology for customized therapy
Q47798673The mechanisms underlying the production of discontinuous gas exchange cycles in insects
Q38227865The nucleus of the solitary tract and the coordination of respiratory and sympathetic activities
Q41970894The ongoing need for good physiological investigation: obstructive sleep apnea in HIV patients as a paradigm
Q48190404The predictive value of Muller's maneuvre for CPAP titration in OSAHS patients
Q47799287The rat cerebral vasculature exhibits time-of-day-dependent oscillations in circadian clock genes and vascular function that are attenuated following obstructive sleep apnea
Q37446892The relation between sleep and weight in a suburban sleep center: observations and speculations on apnea and weight
Q47642170The role of hypoxia-inducible factors in carotid body (patho) physiology.
Q55064054The role of loop gain in predicting upper airway surgical outcomes-what do we know?
Q47122578The role of sleepiness on arterial stiffness improvement after CPAP therapy in males with obstructive sleep apnea: a prospective cohort study
Q38722814The role of telemedicine in obstructive sleep apnea management
Q55283429The use of drug-induced sleep endoscopy in England and Belgium.
Q43626222The use of dual-energy X-ray absorptiometry in the evaluation of obesity in women with obstructive sleep apnea-hypopnea syndrome.
Q37599616Three hours of intermittent hypoxia increases circulating glucose levels in healthy adults
Q90287454Three-dimensional volumetric magnetic resonance imaging (MRI) analysis of the soft palate and nasopharynx in brachycephalic and non-brachycephalic dog breeds
Q48030804Time of day affects chemoreflex sensitivity and the carbon dioxide reserve during NREM sleep in participants with sleep apnea
Q47954720Time of day affects the frequency and duration of breathing events and the critical closing pressure during NREM sleep in participants with sleep apnea
Q51645835Time-varying signal analysis to detect high-altitude periodic breathing in climbers ascending to extreme altitude.
Q45323315Toll-like receptor activity in patients with obstructive sleep apnea
Q38039502Tongue anatomy and physiology, the scientific basis for a novel targeted neurostimulation system designed for the treatment of obstructive sleep apnea
Q36004147Tonic and phasic drive to medullary respiratory neurons during periodic breathing.
Q36752050Translational approaches to understanding metabolic dysfunction and cardiovascular consequences of obstructive sleep apnea
Q37637184Treatment of obstructive sleep apnea alters cancer-associated transcriptional signatures in circulating leukocytes.
Q38302944Tumor circulating DNA profiling in xenografted mice exposed to intermittent hypoxia
Q30360424Ultrasonographic Detection of Airway Obstruction in a Model of Obstructive Sleep Apnea.
Q98385778Ultrasonographic Measurement of Pharyngeal-Airway Dimension and Its Relationship with Obesity and Sleep-Disordered Breathing
Q35597819Uncoupling protein-2 mRNA expression in mice subjected to intermittent hypoxia
Q89287564Understanding Pathophysiological Concepts Leading to Obstructive Apnea
Q98772430Updates on management of pediatric obstructive sleep apnea
Q35615468Upper Airway Stimulation for Obstructive Sleep Apnea: Past, Present, and Future
Q58121715Ventilatory and Autonomic Regulation in Sleep Apnea Syndrome: A Potential Protective Role for Erythropoietin?
Q42120765Ventilatory oscillations at exercise: effects of hyperoxia, hypercapnia, and acetazolamide
Q49106586Ventral hippocampus modulates bradycardic response to peripheral chemoreflex activation in awake rats
Q37247926Vitamin D Concentrations and Obstructive Sleep Apnea in a Multicenter Cohort of Older Males
Q48036106WITHDRAWN: Sleep quality changes in chronically depressed patients treated with mindfulness-based cognitive therapy or cognitive behavioral analysis system for psychotherapy: a pilot study
Q64298382Working Time Society consensus statements: Evidence-based effects of shift work on physical and mental health
Q45344902Worsening of central sleep apnea at high altitude--a role for cerebrovascular function
Q36686466Zopiclone Increases the Arousal Threshold without Impairing Genioglossus Activity in Obstructive Sleep Apnea.
Q87139228[Sleep apnea and heart failure]
Q35104879eAMI: a qualitative quantification of periodic breathing based on amplitude of oscillations
Q34414609β2-Adrenergic receptor-dependent attenuation of hypoxic pulmonary vasoconstriction prevents progression of pulmonary arterial hypertension in intermittent hypoxic rats

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