Role of histone deacetylase Rpd3 in regulating rRNA gene transcription and nucleolar structure in yeast

scientific article

Role of histone deacetylase Rpd3 in regulating rRNA gene transcription and nucleolar structure in yeast is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/MCB.26.10.3889-3901.2006
P932PMC publication ID1489006
P698PubMed publication ID16648483
P5875ResearchGate publication ID7133813

P50authorSarah L. FrenchQ64590298
P2093author name stringJohn P Aris
Ann L Beyer
Masayasu Nomura
Imran Siddiqi
Manabu Sato
Loan Vu
Melanie L Oakes
P2860cites workmTOR-dependent activation of the transcription factor TIF-IA links rRNA synthesis to nutrient availabilityQ24607244
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylaseQ27860668
Chromatin-mediated regulation of nucleolar structure and RNA Pol I localization by TORQ27930272
An approach for isolation of mutants defective in 35S ribosomal RNA synthesis in Saccharomyces cerevisiaeQ27930691
Microarray deacetylation maps determine genome-wide functions for yeast histone deacetylasesQ27931861
Multiprotein transcription factor UAF interacts with the upstream element of the yeast RNA polymerase I promoter and forms a stable preinitiation complex.Q27931925
A new role for a yeast transcriptional silencer gene, SIR2, in regulation of recombination in ribosomal DNA.Q27932277
A genetic screen for ribosomal DNA silencing defects identifies multiple DNA replication and chromatin-modulating factorsQ27933069
Histones H3 and H4 are components of upstream activation factor required for the high-level transcription of yeast rDNA by RNA polymerase IQ27934091
A general requirement for the Sin3-Rpd3 histone deacetylase complex in regulating silencing in Saccharomyces cerevisiae.Q27934391
Reconstitution of yeast RNA polymerase I transcription in vitro from purified components. TATA-binding protein is not required for basal transcriptionQ27935304
Transcription of chromosomal rRNA genes by both RNA polymerase I and II in yeast uaf30 mutants lacking the 30 kDa subunit of transcription factor UAFQ27935374
Labeling of RNA and phosphoproteins in Saccharomyces cerevisiaeQ70120838
Ribosome synthesis during the growth cycle of Saccharomyces cerevisiaeQ72515066
RRN3 gene of Saccharomyces cerevisiae encodes an essential RNA polymerase I transcription factor which interacts with the polymerase independently of DNA template.Q27936787
Regulation of ribosome biogenesis by the rapamycin-sensitive TOR-signaling pathway in Saccharomyces cerevisiaeQ27937080
Exit from mitosis is triggered by Tem1-dependent release of the protein phosphatase Cdc14 from nucleolar RENT complexQ27937157
HDA1 and RPD3 are members of distinct yeast histone deacetylase complexes that regulate silencing and transcriptionQ27937238
Cfi1 prevents premature exit from mitosis by anchoring Cdc14 phosphatase in the nucleolusQ29615267
Extrachromosomal rDNA circles--a cause of aging in yeastQ29618308
Transcriptional silencing in yeast is associated with reduced nucleosome acetylationQ29618497
Transcriptional silencing of Ty1 elements in the RDN1 locus of yeastQ29618830
An unusual form of transcriptional silencing in yeast ribosomal DNAQ29618831
RPD3 is required for the inactivation of yeast ribosomal DNA genes in stationary phaseQ30309921
RNA polymerase I propagates unidirectional spreading of rDNA silent chromatinQ30310369
In exponentially growing Saccharomyces cerevisiae cells, rRNA synthesis is determined by the summed RNA polymerase I loading rate rather than by the number of active genesQ30310526
Tor Pathway Regulates Rrn3p-dependent Recruitment of Yeast RNA Polymerase I to the Promoter but Does Not Participate in Alteration of the Number of Active GenesQ30449935
A specialized form of RNA polymerase I, essential for initiation and growth-dependent regulation of rRNA synthesis, is disrupted during transcriptionQ33889052
Ordered nucleation and spreading of silenced chromatin in Saccharomyces cerevisiae.Q33893339
Sir2 links chromatin silencing, metabolism, and agingQ33901751
Differential roles of phosphorylation in the formation of transcriptional active RNA polymerase I.Q33951831
Histone acetylation and deacetylation in yeastQ34187792
"Sleeping beauty": quiescence in Saccharomyces cerevisiaeQ34348944
Tor signalling in bugs, brain and brawnQ35058522
RNA polymerase switch in transcription of yeast rDNA: role of transcription factor UAF (upstream activation factor) in silencing rDNA transcription by RNA polymerase II.Q35125953
At the interface between signaling and executing anaphase--Cdc14 and the FEAR networkQ35936135
Mutational analysis of the structure and localization of the nucleolus in the yeast Saccharomyces cerevisiaeQ36255523
Efficient transcriptional silencing in Saccharomyces cerevisiae requires a heterochromatin histone acetylation patternQ36561489
The yeast nucleolar protein Cbf5p is involved in rRNA biosynthesis and interacts genetically with the RNA polymerase I transcription factor RRN3.Q36573301
Structural alterations of the nucleolus in mutants of Saccharomyces cerevisiae defective in RNA polymerase I.Q36678953
RPD3 encodes a second factor required to achieve maximum positive and negative transcriptional states in Saccharomyces cerevisiaeQ36744711
Transcription factor UAF, expansion and contraction of ribosomal DNA (rDNA) repeats, and RNA polymerase switch in transcription of yeast rDNAQ39449635
Rapamycin induces the G0 program of transcriptional repression in yeast by interfering with the TOR signaling pathwayQ39575463
Steps in assembly of silent chromatin in yeast: Sir3-independent binding of a Sir2/Sir4 complex to silencers and role for Sir2-dependent deacetylationQ39674793
The tor pathway regulates gene expression by linking nutrient sensing to histone acetylationQ39739761
Transcription in the yeast rRNA gene locus: distribution of the active gene copies and chromatin structure of their flanking regulatory sequencesQ40017238
Chromatin structures and transcription of rDNA in yeast Saccharomyces cerevisiaeQ40407137
Rrn3 phosphorylation is a regulatory checkpoint for ribosome biogenesisQ40731596
Direct evidence for SIR2 modulation of chromatin structure in yeast rDNA.Q42631705
Highly specific antibodies determine histone acetylation site usage in yeast heterochromatin and euchromatinQ43430561
Rpd3p relocation mediates a transcriptional response to rapamycin in yeastQ44880724
Silencing in yeast rDNA chromatin: reciprocal relationship in gene expression between RNA polymerase I and II.Q45998087
SIR2 regulates recombination between different rDNA repeats, but not recombination within individual rRNA genes in yeastQ47619702
P433issue10
P407language of work or nameEnglishQ1860
P304page(s)3889-3901
P577publication date2006-05-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleRole of histone deacetylase Rpd3 in regulating rRNA gene transcription and nucleolar structure in yeast
P478volume26

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cites work (P2860)
Q30357437Cell growth control: little eukaryotes make big contributions.
Q37299868Chromatin: linking structure and function in the nucleolus
Q37250667Coordination of Ribosomal Protein and Ribosomal RNA Gene Expression in Response to TOR Signaling.
Q33742112DSIF and RNA Polymerase II CTD Phosphorylation Coordinate the Recruitment of Rpd3S to Actively Transcribed Genes
Q24313528Epigenetic control of rDNA loci in response to intracellular energy status
Q34747109Functional divergence of eukaryotic RNA polymerases: unique properties of RNA polymerase I suit its cellular role
Q27937728Genetic identification of factors that modulate ribosomal DNA transcription in Saccharomyces cerevisiae.
Q89966219H3K9 Demethylation-Induced R-Loop Accumulation Is Linked to Disorganized Nucleoli
Q35603101RNA polymerase I activity is regulated at multiple steps in the transcription cycle: recent insights into factors that influence transcription elongation.
Q36035266Ribosome quality control is a central protection mechanism for yeast exposed to deoxynivalenol and trichothecin
Q35071642Sir2 represses endogenous polymerase II transcription units in the ribosomal DNA nontranscribed spacer
Q28754860Switching from prokaryotic molecular biology to eukaryotic molecular biology
Q27937453TOR-dependent reduction in the expression level of Rrn3p lowers the activity of the yeast RNA Pol I machinery, but does not account for the strong inhibition of rRNA production
Q36210184The Histone Deacetylase Gene Rpd3 Is Required for Starvation Stress Resistance
Q61806371The path of pre-ribosomes through the nuclear pore complex revealed by electron tomography
Q27931478The transcription elongation factor Spt5 influences transcription by RNA polymerase I positively and negatively
Q27938936Transcription of multiple yeast ribosomal DNA genes requires targeting of UAF to the promoter by Uaf30.
Q36954385Yeast linker histone Hho1p is required for efficient RNA polymerase I processivity and transcriptional silencing at the ribosomal DNA

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