Effects of sildenafil and/or muscle derived stem cells on myocardial infarction

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Effects of sildenafil and/or muscle derived stem cells on myocardial infarction is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1004514359
P356DOI10.1186/1479-5876-10-159
P932PMC publication ID3476974
P698PubMed publication ID22871104
P5875ResearchGate publication ID230631678

P50authorNestor F Gonzalez-CadavidQ92730697
Dolores VernetQ122228091
P2093author name stringGaby Nolazco
George E Kopchok
Istvan Kovanecz
Judy Sc Wang
Rodney A White
Sheryl L Chow
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Comparative human pharmacokinetics and metabolism of single-dose oral and intravenous sildenafilQ41822316
Myocardial remodeling is controlled by myocyte-targeted gene regulation of phosphodiesterase type 5.Q42094814
cGMP modulates stem cells differentiation to neurons in brain in vivoQ43230613
Quantitative comparison of toxicity of anticancer agents in mouse, rat, hamster, dog, monkey, and man.Q43706400
Sildenafil (Viagra) attenuates ischemic cardiomyopathy and improves left ventricular function in miceQ44935527
Preconditioning by phosphodiesterase-5 inhibition improves therapeutic efficacy of adipose-derived stem cells following myocardial infarction in miceQ44970917
Early onset of fibrosis within the arterial media in a rat model of type 2 diabetes mellitus with erectile dysfunction.Q46025702
Long-term continuous treatment with sildenafil ameliorates aging-related erectile dysfunction and the underlying corporal fibrosis in the rat.Q46600601
In vivo analysis of chronic phosphodiesterase-5 inhibition with sildenafil in penile erectile tissues: no tachyphylaxis effectQ46689741
Effect of muscle-derived stem cells on the restoration of corpora cavernosa smooth muscle and erectile function in the aged rat.Q46738229
The phosphodiesterase-5 inhibitor tadalafil reduces myocardial infarct sizeQ46785598
Phosphodiesterase type 5 is not upregulated by tadalafil in cultures of human penile cellsQ46892052
PDE5A inhibition attenuates bleomycin-induced pulmonary fibrosis and pulmonary hypertension through inhibition of ROS generation and RhoA/Rho kinase activationQ46927614
Chronic daily tadalafil prevents the corporal fibrosis and veno-occlusive dysfunction that occurs after cavernosal nerve resectionQ46987652
Long-term continuous sildenafil treatment ameliorates corporal veno-occlusive dysfunction (CVOD) induced by cavernosal nerve resection in rats.Q46991340
Phosphodiesterase 5A inhibition induces Na+/H+ exchanger blockade and protection against myocardial infarctionQ48252402
Involvement of the nitric oxide-soluble guanylyl cyclase pathway in the oxytocin-mediated differentiation of porcine bone marrow stem cells into cardiomyocytesQ60758048
Differential myocardial infarct repair with muscle stem cells compared to myoblastsQ81123128
A relationship between vascular endothelial growth factor, angiogenesis, and cardiac repair after muscle stem cell transplantation into ischemic heartsQ81469764
Isolation of a slowly adhering cell fraction containing stem cells from murine skeletal muscle by the preplate techniqueQ81932797
Cardiomyocyte formation by skeletal muscle-derived multi-myogenic stem cells after transplantation into infarcted myocardiumQ27301781
Cytokines regulate matrix metalloproteinases and migration in cardiac fibroblastsQ30480210
Renin-angiotensin-aldosterone system blockade for cardiovascular diseases: current statusQ34124779
Early combined treatment with sildenafil and adipose-derived mesenchymal stem cells preserves heart function in rat dilated cardiomyopathyQ34208448
Phosphodiesterase-5 inhibitor, tadalafil, protects against myocardial ischemia/reperfusion through protein-kinase g-dependent generation of hydrogen sulfideQ34503391
Sildenafil and vardenafil but not nitroglycerin limit myocardial infarction through opening of mitochondrial K(ATP) channels when administered at reperfusion following ischemia in rabbitsQ34543457
Attenuation of Doxorubicin-induced Cardiotoxicity by Tadalafil: A Long Acting Phosphodiesterase-5 Inhibitor.Q34793299
Cardiac mesenchymal stem cells contribute to scar formation after myocardial infarctionQ35037360
Mitigation of the progression of heart failure with sildenafil involves inhibition of RhoA/Rho-kinase pathwayQ35056906
Up and down-regulation of phosphodiesterase-5 as related to tachyphylaxis and priapismQ35174777
Emerging new uses of phosphodiesterase-5 inhibitors in cardiovascular diseases.Q35500693
Stimulating vaginal repair in rats through skeletal muscle-derived stem cells seeded on small intestinal submucosal scaffolds.Q35553198
Differential expression of PDE5 in failing and nonfailing human myocardiumQ35680934
Differentiation of muscle-derived cells into myofibroblasts in injured skeletal muscleQ35789114
Cardiovascular protection with sildenafil following chronic inhibition of nitric oxide synthaseQ36357896
Myostatin genetic inactivation inhibits myogenesis by muscle-derived stem cells in vitro but not when implanted in the mdx mouse muscle.Q36998190
Role of nitric oxide signaling components in differentiation of embryonic stem cells into myocardial cells.Q36999849
ERK phosphorylation mediates sildenafil-induced myocardial protection against ischemia-reperfusion injury in mice.Q37200237
Myogenic endothelial cells purified from human skeletal muscle improve cardiac function after transplantation into infarcted myocardiumQ37286527
Antifibrotic effects of pioglitazone on the kidney in a rat model of type 2 diabetes mellitusQ37306331
Sildenafil-mediated neovascularization and protection against myocardial ischaemia reperfusion injury in rats: role of VEGF/angiopoietin-1Q37310691
The role of the renin-angiotensin-aldosterone system in cardiovascular progenitor cell function.Q37366776
Mechanisms of penile fibrosisQ37408368
Novel pharmacotherapies to abrogate postinfarction ventricular remodelingQ37437162
Phosphodiesterase 5 inhibition in heart failure: mechanisms and clinical implicationsQ37450782
Cardiac fibroblasts: at the heart of myocardial remodelingQ37491524
Erectile dysfunction following prostatectomy: prevention and treatmentQ37573390
Treatment of Peyronie's disease with PDE5 inhibitors: an antifibrotic strategyQ37704966
Postconditioning and protection from reperfusion injury: where do we stand? Position paper from the Working Group of Cellular Biology of the Heart of the European Society of CardiologyQ37744271
Stem cell therapy for chronic myocardial infarctionQ37766194
Regulation and dysregulation of fibrosis in skeletal muscleQ37767061
Role of myofibroblasts in vascular remodelling: focus on restenosis and aneurysm.Q37771768
Left ventricular remodeling in the post-infarction heart: a review of cellular, molecular mechanisms, and therapeutic modalitiesQ37771886
P407language of work or nameEnglishQ1860
P921main subjectmyocardial infarctionQ12152
P304page(s)159
P577publication date2012-08-07
P1433published inJournal of Translational MedicineQ15716664
P1476titleEffects of sildenafil and/or muscle derived stem cells on myocardial infarction
P478volume10

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cites work (P2860)
Q90344621Dyslipidemia Is a Major Factor in Stem Cell Damage Induced by Uncontrolled Long-Term Type 2 Diabetes and Obesity in the Rat, as Suggested by the Effects on Stem Cell Culture
Q37353891Human Umbilical Cord Blood for Transplantation Therapy in Myocardial Infarction
Q36951110Implanted Muscle-Derived Stem Cells Ameliorate Erectile Dysfunction in a Rat Model of Type 2 Diabetes, but Their Repair Capacity Is Impaired by Their Prior Exposure to the Diabetic Milieu
Q90056593Microenergy acoustic pulses induced myogenesis of urethral striated muscle stem/progenitor cells
Q37646812Muscle Derived Stem Cells Stimulate Muscle Myofiber Repair and Counteract Fat Infiltration in a Diabetic Mouse Model of Critical Limb Ischemia.
Q36998190Myostatin genetic inactivation inhibits myogenesis by muscle-derived stem cells in vitro but not when implanted in the mdx mouse muscle.
Q41600750Separate or combined treatments with daily sildenafil, molsidomine, or muscle-derived stem cells prevent erectile dysfunction in a rat model of cavernosal nerve damage.
Q35116422The transcriptional signatures of cells from the human Peyronie's disease plaque and the ability of these cells to generate a plaque in a rat model suggest potential therapeutic targets

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