Deletion of tetraspanin Cd151 results in decreased pathologic angiogenesis in vivo and in vitro

scientific article

Deletion of tetraspanin Cd151 results in decreased pathologic angiogenesis in vivo and in vitro is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1182/BLOOD-2006-08-041970
P932PMC publication ID1794066
P698PubMed publication ID17023588
P5875ResearchGate publication ID6770649

P2093author name stringAlexander R Kazarov
Arja Kaipainen
Martin E Hemler
Laura E Benjamin
Yoshito Takeda
Benjamin D Hopkins
Catherine E Butterfield
P2860cites workFunction of the tetraspanin CD151-alpha6beta1 integrin complex during cellular morphogenesisQ24555041
Annexin II regulates fibrin homeostasis and neoangiogenesis in vivoQ24623508
Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivoQ24648140
Akt1 in endothelial cell and angiogenesisQ24676614
PETA-3/CD151, a member of the transmembrane 4 superfamily, is localised to the plasma membrane and endocytic system of endothelial cells, associates with multiple integrins and modulates cell functionQ28137736
Eukaryotic expression cloning with an antimetastatic monoclonal antibody identifies a tetraspanin (PETA-3/CD151) as an effector of human tumor cell migration and metastasisQ28142104
Laminin-10/11 and fibronectin differentially regulate integrin-dependent Rho and Rac activation via p130(Cas)-CrkII-DOCK180 pathwayQ28190218
Laminin-10/11 and fibronectin differentially prevent apoptosis induced by serum removal via phosphatidylinositol 3-kinase/Akt- and MEK1/ERK-dependent pathwaysQ28206731
Complexes of tetraspanins with integrins: more than meets the eyeQ28210099
CD151 enhances cell motility and metastasis of cancer cells in the presence of focal adhesion kinaseQ28214450
Localization of the transmembrane 4 superfamily (TM4SF) member PETA-3 (CD151) in normal human tissues: comparison with CD9, CD63, and alpha5beta1 integrinQ28235612
Tetraspanin functions and associated microdomainsQ28284176
Developmental regulation of the laminin alpha5 chain suggests a role in epithelial and endothelial cell maturationQ28505309
SRC binding to the cytoskeleton, triggered by growth cone attachment to laminin, is protein tyrosine phosphatase-dependentQ28578043
Characterization of mice lacking the tetraspanin superfamily member CD151Q28587010
Beta4 integrin is required for hemidesmosome formation, cell adhesion and cell survivalQ28592841
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Endothelial/pericyte interactionsQ29619802
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Basement membranes: structure, assembly and role in tumour angiogenesisQ29622882
A critical role for tetraspanin CD151 in alpha3beta1 and alpha6beta4 integrin-dependent tumor cell functions on laminin-5Q30477393
Tetraspanin CD151 regulates alpha6beta1 integrin adhesion strengtheningQ30478308
Mapping of tetraspanin-enriched microdomains that can function as gateways for HIV-1.Q30480407
Integrin signaling via the PI3-kinase-Akt pathway increases neuronal resistance to glutamate-induced apoptosisQ32134580
Angiogenesis and vasculogenesis are impaired in the precocious-aging klotho mouseQ33205670
The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animalsQ33688733
Potentiation of the ligand-binding activity of integrin alpha3beta1 via association with tetraspanin CD151Q33837431
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Tetraspanin Proteins Mediate Cellular Penetration, Invasion, and Fusion Events and Define a Novel Type of Membrane MicrodomainQ35564822
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Palmitoylation supports assembly and function of integrin-tetraspanin complexesQ36322840
Integrins and angiogenesis: a sticky businessQ36330257
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Dose-dependent response of FGF-2 for lymphangiogenesisQ37415307
Between molecules and morphology. Extracellular matrix and creation of vascular form.Q40421562
Role of extracellular matrix in regulation of staurosporine-induced apoptosis in breast cancer cells.Q40448713
Integrin engagement differentially modulates epithelial cell motility by RhoA/ROCK and PAK1.Q40478610
Alpha 3 beta 1 integrin promotes keratinocyte cell survival through activation of a MEK/ERK signaling pathwayQ40530851
Specific interactions among transmembrane 4 superfamily (TM4SF) proteins and phosphoinositide 4-kinaseQ40847493
Regulation of endothelial cell motility by complexes of tetraspan molecules CD81/TAPA-1 and CD151/PETA-3 with alpha3 beta1 integrin localized at endothelial lateral junctionsQ41035046
p38 MAPK is a critical regulator of the constitutive and the beta4 integrin-regulated expression of IL-6 in human normal thymic epithelial cells.Q42451854
Function of alpha3beta1-tetraspanin protein complexes in tumor cell invasion. Evidence for the role of the complexes in production of matrix metalloproteinase 2 (MMP-2).Q42870963
Transmembrane-4 superfamily proteins associate with activated protein kinase C (PKC) and link PKC to specific beta(1) integrinsQ43590665
NSAIDs inhibit alpha V beta 3 integrin-mediated and Cdc42/Rac-dependent endothelial-cell spreading, migration and angiogenesis.Q43726776
Association of the tetraspanin CD151 with the laminin-binding integrins alpha3beta1, alpha6beta1, alpha6beta4 and alpha7beta1 in cells in culture and in vivoQ43909564
Retinal vascular development is mediated by endothelial filopodia, a preexisting astrocytic template and specific R-cadherin adhesion.Q44198738
Angiogenesis in collagen I requires alpha2beta1 ligation of a GFP*GER sequence and possibly p38 MAPK activation and focal adhesion disassemblyQ44467145
Antiangiogenic and antitumor efficacy of EphA2 receptor antagonistQ44761792
Matrix-specific activation of Src and Rho initiates capillary morphogenesis of endothelial cellsQ44788587
The tetraspanin superfamily member CD151 regulates outside-in integrin alphaIIbbeta3 signaling and platelet function.Q44958582
Differential expression of pro- and antiangiogenic factors in mouse strain-dependent hypoxia-induced retinal neovascularizationQ46459264
The integrin alpha6beta1 modulation of PI3K and Cdc42 activities induces dynamic filopodium formation in human plateletsQ46756082
Regulation of skin microvasculature angiogenesis, cell migration, and permeability by a specific inhibitor of PKCalphaQ46865497
Deletion of laminin-8 results in increased tumor neovascularization and metastasis in mice.Q47324578
Laminin-1 promotes angiogenesis in synergy with fibroblast growth factor by distinct regulation of the gene and protein expression profile in endothelial cells.Q47880744
The mouse aorta model: influence of genetic background and aging on bFGF- and VEGF-induced angiogenic sproutingQ47889556
Tensional forces in fibrillar extracellular matrices control directional capillary sprouting.Q48749055
CD151, the first member of the tetraspanin (TM4) superfamily detected on erythrocytes, is essential for the correct assembly of human basement membranes in kidney and skinQ50335739
Absence of integrin alpha 6 leads to epidermolysis bullosa and neonatal death in mice.Q52200996
MT1-MMP expression promotes tumor growth and angiogenesis through an up-regulation of vascular endothelial growth factor expression.Q53876521
Integrin β4 signaling promotes tumor angiogenesisQ57359862
Enhanced pathological angiogenesis in mice lacking β3 integrin or β3 and β5 integrinsQ61631829
Protein kinase C and downstream signaling pathways in a three-dimensional model of phorbol ester-induced angiogenesisQ61815743
The Cdc42 and Rac1 GTPases are required for capillary lumen formation in three-dimensional extracellular matricesQ64379046
A model of angiogenesis in the mouse corneaQ71174063
Alpha 3 beta 1 integrin has a crucial role in kidney and lung organogenesisQ71849956
Regulation of endothelial cell morphogenesis by integrins, mechanical forces, and matrix guidance pathwaysQ72390027
Clinical significance of CD151 gene expression in non-small cell lung cancerQ77372883
PKCalpha activates eNOS and increases arterial blood flow in vivoQ81009178
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectangiogenesisQ539568
P304page(s)1524-1532
P577publication date2006-10-05
P1433published inBloodQ885070
P1476titleDeletion of tetraspanin Cd151 results in decreased pathologic angiogenesis in vivo and in vitro
P478volume109