Nuclear factor kappaB deficiency is associated with auditory nerve degeneration and increased noise-induced hearing loss.

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Nuclear factor kappaB deficiency is associated with auditory nerve degeneration and increased noise-induced hearing loss. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1523/JNEUROSCI.2488-05.2006
P932PMC publication ID2897814
P698PubMed publication ID16571762

P50authorHainan LangQ55207665
P2093author name stringRichard A Schmiedt
Bradley A Schulte
Daohong Zhou
Samuel S Spicer
Nancy Smythe
P2860cites workExcitotoxicity, synaptic repair, and functional recovery in the mammalian cochlea: a review of recent findingsQ28145843
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NF-kappaB is required for survival of immature auditory hair cells in vitroQ30492606
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Ouabain induces apoptotic cell death in type I spiral ganglion neurons, but not type II neuronsQ30492621
Lateral wall histopathology and endocochlear potential in the noise-damaged mouse cochleaQ30500463
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Quinolinic acid-induced increases in calbindin D28k immunoreactivity in rat striatal neurons in vivo and in vitro mimic the pattern seen in Huntington's diseaseQ38298264
Inhibition of the c-Jun N-terminal kinase signaling pathway influences neurite outgrowth of spiral ganglion neurons in vitroQ40621038
Cyclic AMP elevation is sufficient to promote the survival of spinal motor neurons in vitro.Q41008887
Kainic acid selectively alters auditory dendrites connected with cochlear inner hair cellsQ41340554
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Targeted disruption of the p50 subunit of NF-kappa B leads to multifocal defects in immune responsesQ42488424
Endoplasmic reticulum D-myo-inositol 1,4,5-trisphosphate-sensitive stores regulate nuclear factor-kappaB binding activity in a calcium-independent mannerQ42502990
Opposite actions of brain-derived neurotrophic factor and neurotrophin-3 on firing features and ion channel composition of murine spiral ganglion neurons.Q42517558
Lack of NF-kappaB p50 exacerbates degeneration of hippocampal neurons after chemical exposure and impairs learningQ42526530
Molecular characterization of synaptophysin, a major calcium-binding protein of the synaptic vesicle membraneQ42566319
Activation of the nuclear factor-kappaB is a key event in brain tolerance.Q43653405
Ca2+/calmodulin-dependent protein kinases II and IV both promote survival but differ in their effects on axon growth in spiral ganglion neurons.Q44387882
Substance P protects spiral ganglion neurons from apoptosis via PKC-Ca2+-MAPK/ERK pathwaysQ44597300
Noise induces A1 adenosine receptor expression in the chinchilla cochleaQ44753753
Nuclear factor-(kappa)B modulates the p53 response in neurons exposed to DNA damage.Q44814700
Auditory-nerve activity in cats exposed to ototoxic drugs and high-intensity soundsQ45008212
Chronic excitotoxicity in the guinea pig cochlea induces temporary functional deficits without disrupting otoacoustic emissions.Q45065022
NF-kappaB pathway protects cochlear hair cells from aminoglycoside-induced ototoxicityQ45239520
Primary Structural Changes in the Organ of Corti After Acoustic OverstimulationQ46193056
Suppression of calcium release from inositol 1,4,5-trisphosphate-sensitive stores mediates the anti-apoptotic function of nuclear factor-kappaB.Q46425809
Excitotoxicity and repair of cochlear synapses after noise-trauma induced hearing loss.Q46614189
Developmental changes in human cerebellum: expression of intracellular calcium receptors, calcium-binding proteins, and phosphorylated and nonphosphorylated neurofilament proteinQ47893659
Lack of the p50 subunit of nuclear factor-kappaB increases the vulnerability of hippocampal neurons to excitotoxic injuryQ48093930
Effects of aging, hearing loss, and anatomical location on thresholds of inferior colliculus neurons in C57BL/6 and CBA miceQ48313119
Auditory peripheral influences on calcium binding protein immunoreactivity in the cochlear nucleus during aging in the C57BL/6J mouseQ48313210
Time-dependence and cell-type specificity of synergistic neurotrophin actions on spiral ganglion neuronsQ48341227
NF-kappaB p50 is increased in neurons surviving hippocampal injuryQ48708549
Recovery of structure and function of inner ear afferent synapses following kainic acid excitotoxicityQ48786829
BDNF synthesis in spiral ganglion neurons is constitutive and CREB-dependent.Q48866529
Supranuclear efferent synapses on outer hair cells and Deiters' cells in the human organ of CortiQ49164334
Survival of adult spiral ganglion neurons requires erbB receptor signaling in the inner ear.Q50477414
Synaptic arrangements between inner hair cells and tunnel fibers in the mouse cochlea.Q50480218
Endocochlear potentials and compound action potential recovery: functions in the C57BL/6J mouse.Q50486241
Recovery of kainic acid excitotoxicity in chinchilla cochlea.Q50495980
Pattern of degeneration of the spiral ganglion cell and its processes in the C57BL/6J mouse.Q50497386
Quantitative measures of hair cell loss in CBA and C57BL/6 mice throughout their life spans.Q50509166
Distortion product otoacoustic emissions in hearing-impaired mutant mice.Q50582118
Functional significance of dendritic swelling after loud sounds in the guinea pig cochlea.Q50593067
Further observations of the efferent cochlear bundle.Q51346581
Expression of plasma membrane Ca-ATPase in the adult and developing gerbil cochlea.Q52204442
Constitutive nuclear factor-kappa B activity is required for central neuron survival.Q53664694
Innervation Patterns in the Organ of Corti of the CatQ58178732
Afferent and efferent innervation of the cat cochlea: quantitative analysis with light and electron microscopyQ68637686
The human spiral ganglionQ71690546
Evidence for calcium-binding proteins and calcium-dependent regulatory proteins in sensory cells of the organ of CortiQ72694918
Distribution of frequenin in the mouse inner ear during development, comparison with other calcium-binding proteins and synaptophysinQ73187106
[Lipopolysaccharide enhances DNA binding activity of nuclear factor-kappa B in the mouse cochlea]Q73440215
Immunolocalization of calbindin D28k and calretinin in the dog cochlea during postnatal developmentQ73924892
Secreted beta-amyloid precursor protein counteracts the proapoptotic action of mutant presenilin-1 by activation of NF-kappaB and stabilization of calcium homeostasisQ74516844
Intracellular neuronal calcium sensor proteins: a family of EF-hand calcium-binding proteins in search of a functionQ77946327
An extranuclear locus of cAMP-dependent protein kinase action is necessary and sufficient for promotion of spiral ganglion neuronal survival by cAMPQ78946402
P433issue13
P407language of work or nameEnglishQ1860
P921main subjecthearing lossQ16035842
nerve degenerationQ54971278
P304page(s)3541-3550
P577publication date2006-03-01
P1433published inJournal of NeuroscienceQ1709864
P1476titleNuclear factor kappaB deficiency is associated with auditory nerve degeneration and increased noise-induced hearing loss
P478volume26

Reverse relations

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