Prevention of Ventricular Arrhythmia and Calcium Dysregulation in a Catecholaminergic Polymorphic Ventricular Tachycardia Mouse Model Carrying Calsequestrin-2 Mutation

scientific article published on August 30, 2010

Prevention of Ventricular Arrhythmia and Calcium Dysregulation in a Catecholaminergic Polymorphic Ventricular Tachycardia Mouse Model Carrying Calsequestrin-2 Mutation is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/J.1540-8167.2010.01877.X
P953full work available at URLhttps://europepmc.org/articles/PMC3053436
https://europepmc.org/articles/pmc3053436?pdf=render
https://europepmc.org/articles/PMC3053436?pdf=render
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20807279/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20807279/pdf/?tool=EBI
http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1540-8167.2010.01877.x/fullpdf
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1540-8167.2010.01877.x
https://doi.org/10.1111/j.1540-8167.2010.01877.x
P932PMC publication ID3053436
P698PubMed publication ID20807279
P5875ResearchGate publication ID46107031

P50authorChristine E. SeidmanQ30123970
P2093author name stringLibin Wang
Charles I. Berul
Michael Arad
Tetsuo Konno
Ronny Alcalai
David Planer
Hiroko Wakimoto
Jon G. Seidman
P2860cites workSudden death in familial polymorphic ventricular tachycardia associated with calcium release channel (ryanodine receptor) leakQ24296910
Clinical phenotype and functional characterization of CASQ2 mutations associated with catecholaminergic polymorphic ventricular tachycardiaQ24299780
Ryanodine receptor mutations associated with stress-induced ventricular tachycardia mediate increased calcium release in stimulated cardiomyocytesQ24315860
Flecainide prevents catecholaminergic polymorphic ventricular tachycardia in mice and humansQ24608179
Catecholaminergic polymorphic ventricular tachycardia: electrocardiographic characteristics and optimal therapeutic strategies to prevent sudden deathQ24674590
Mutations of the cardiac ryanodine receptor (RyR2) gene in familial polymorphic ventricular tachycardiaQ28142708
Mutations in the cardiac ryanodine receptor gene (hRyR2) underlie catecholaminergic polymorphic ventricular tachycardiaQ28201561
A missense mutation in a highly conserved region of CASQ2 is associated with autosomal recessive catecholamine-induced polymorphic ventricular tachycardia in Bedouin families from IsraelQ28204838
Calsequestrin 2 (CASQ2) mutations increase expression of calreticulin and ryanodine receptors, causing catecholaminergic polymorphic ventricular tachycardiaQ28235110
Abnormal calcium signaling and sudden cardiac death associated with mutation of calsequestrinQ28237997
Quantitation of proteinQ28279026
Left cardiac sympathetic denervation for catecholaminergic polymorphic ventricular tachycardiaQ28279395
Catecholaminergic polymorphic ventricular tachycardiaQ28287523
Casq2 deletion causes sarcoplasmic reticulum volume increase, premature Ca2+ release, and catecholaminergic polymorphic ventricular tachycardiaQ28589230
Autosomal recessive catecholamine- or exercise-induced polymorphic ventricular tachycardia: clinical features and assignment of the disease gene to chromosome 1p13-21.Q33146452
Clinical and molecular characterization of patients with catecholaminergic polymorphic ventricular tachycardia.Q33147854
Bidirectional ventricular tachycardia and fibrillation elicited in a knock-in mouse model carrier of a mutation in the cardiac ryanodine receptor.Q33152686
Calcium channel blockers and beta-blockers versus beta-blockers alone for preventing exercise-induced arrhythmias in catecholaminergic polymorphic ventricular tachycardiaQ33155477
Incidence and risk factors of arrhythmic events in catecholaminergic polymorphic ventricular tachycardiaQ33157356
Catecholaminergic polymorphic ventricular tachycardia in children. A 7-year follow-up of 21 patientsQ33173888
Cardiac electrophysiology in genetically engineered miceQ33882437
Direct binding of verapamil to the ryanodine receptor channel of sarcoplasmic reticulumQ34126333
Cellular mechanisms underlying the development of catecholaminergic ventricular tachycardia.Q34661902
Modulation of SR Ca release by luminal Ca and calsequestrin in cardiac myocytes: effects of CASQ2 mutations linked to sudden cardiac death.Q36791253
Video-assisted thoracoscopic cardiac denervation: a potential novel therapeutic option for children with intractable ventricular arrhythmiasQ37339393
Caffeine induces Ca2+ release by reducing the threshold for luminal Ca2+ activation of the ryanodine receptorQ37355318
ATPase Activities, Ca2+ Transport and Phosphoprotein Formation in Sarcoplasmic Reticulum Subfractions of Fast and Slow Rabbit MusclesQ39840965
Sarcoplasmic reticulum calsequestrins: structural and functional propertiesQ40565740
Modified release verapamil induced cardiogenic shockQ41990514
Calsequestrin: more than 'only' a luminal Ca2+ buffer inside the sarcoplasmic reticulumQ42992388
Intra-sarcoplasmic reticulum Ca2+ oscillations are driven by dynamic regulation of ryanodine receptor function by luminal Ca2+ in cardiomyocytesQ43286787
Quantitative assessment of the SR Ca2+ leak-load relationshipQ44167973
Calcium channel antagonism reduces exercise-induced ventricular arrhythmias in catecholaminergic polymorphic ventricular tachycardia patients with RyR2 mutationsQ45273441
Early changes in excitation-contraction coupling: transition from compensated hypertrophy to failure in Dahl salt-sensitive rat myocytes.Q54135977
Hormonal control of Mg2+ transport in the heartQ59095759
In vivo cardiac electrophysiology studies in the mouseQ71785180
Impaired cell shortening and relengthening with increased pacing frequency are intrinsic to the senescent mouse cardiomyocyteQ73098110
Magnesium inhibition of ryanodine-receptor calcium channels: evidence for two independent mechanismsQ73207956
Absence of calsequestrin 2 causes severe forms of catecholaminergic polymorphic ventricular tachycardiaQ78390804
Arrhythmogenesis in catecholaminergic polymorphic ventricular tachycardia: insights from a RyR2 R4496C knock-in mouse modelQ79851890
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectventricular tachycardiaQ56002
heart arrhythmiaQ189331
tachycardiaQ209583
catecholaminergic polymorphic ventricular tachycardiaQ1649897
P304page(s)316-324
P577publication date2010-08-30
P1433published inJournal of Cardiovascular ElectrophysiologyQ4736917
P1476titlePrevention of ventricular arrhythmia and calcium dysregulation in a catecholaminergic polymorphic ventricular tachycardia mouse model carrying calsequestrin-2 mutation
Prevention of Ventricular Arrhythmia and Calcium Dysregulation in a Catecholaminergic Polymorphic Ventricular Tachycardia Mouse Model Carrying Calsequestrin-2 Mutation
P478volume22

Reverse relations

cites work (P2860)
Q51864131A key role of TRPC channels in the regulation of electromechanical activity of the developing heart.
Q30416051Ageing is associated with deterioration of calcium homeostasis in isolated human right atrial myocytes
Q36941532Calsequestrin 2 deletion shortens the refractoriness of Ca²⁺ release and reduces rate-dependent Ca²⁺-alternans in intact mouse hearts
Q38125941Current perspectives in genetic cardiovascular disorders: from basic to clinical aspects
Q28589538Dynamic, inter-subunit interactions between the N-terminal and central mutation regions of cardiac ryanodine receptor
Q38602828Efficacy and potency of class I antiarrhythmic drugs for suppression of Ca2+ waves in permeabilized myocytes lacking calsequestrin.
Q36559205L-Type Calcium Channels Do Not Play a Critical Role in Chest Blow Induced Ventricular Fibrillation: Commotio Cordis
Q89961129Molecular and tissue mechanisms of catecholaminergic polymorphic ventricular tachycardia
Q38494265Pharmacotherapy for inherited arrhythmia syndromes: mechanistic basis, clinical trial evidence and practical application.
Q33160416Therapeutic approach for patients with catecholaminergic polymorphic ventricular tachycardia: state of the art and future developments

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