Multiple quantitative trait loci modify cochlear hair cell degeneration in the Beethoven (Tmc1Bth) mouse model of progressive hearing loss DFNA36.

scientific article

Multiple quantitative trait loci modify cochlear hair cell degeneration in the Beethoven (Tmc1Bth) mouse model of progressive hearing loss DFNA36. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1534/GENETICS.106.057372
P932PMC publication ID1569729
P698PubMed publication ID16648588
P5875ResearchGate publication ID7131944

P50authorGregory I FrolenkovQ55267329
Tomoko MakishimaQ62940124
Martin Hrabě de AngelisQ28606776
P2093author name stringYoshihiro Noguchi
Helmut Fuchs
Ken Kitamura
Andrew J Griffith
Kiyoto Kurima
P2860cites workA gene responsible for autosomal dominant auditory neuropathy (AUNA1) maps to 13q14-21.Q43073966
Postnatal development in the acoustic system of the house mouse in the light of developing masked thresholdsQ44450814
A chemical-genetic strategy implicates myosin-1c in adaptation by hair cells.Q45712448
Auditory neuropathy in patients carrying mutations in the otoferlin gene (OTOF).Q47367429
Auditory function associated with Col11a1 haploinsufficiency in chondrodysplasia (cho) miceQ48409882
Listening to genetic background noise.Q50473703
The guide to plotting a cochleogram.Q50477106
Early onset and rapid progression of dominant nonsyndromic DFNA36 hearing loss.Q50478228
Nonsyndromic hearing loss caused by a mitochondrial T7511C mutation.Q50486980
Distortion product otoacoustic emissions in hearing-impaired mutant mice.Q50582118
Inner ear pathology in the deafness mutant mouse.Q50592040
Clinical and molecular characterization of a Chinese patient with auditory neuropathy associated with mitochondrial 12S rRNA T1095C mutation.Q55404336
Cochlear origin of 2f1-f2 distortion products assessed by using 2 types of mutant miceQ70213965
Modification of human hearing loss by plasma-membrane calcium pump PMCA2Q24300034
Microtubule-associated protein 1A is a modifier of tubby hearing (moth1).Q24630241
Non-syndromic recessive auditory neuropathy is the result of mutations in the otoferlin (OTOF) geneQ24678650
Characterization of the transmembrane channel-like (TMC) gene family: functional clues from hearing loss and epidermodysplasia verruciformisQ28156114
Dominant and recessive deafness caused by mutations of a novel gene, TMC1, required for cochlear hair-cell functionQ28202014
Myosin-XVa is required for tip localization of whirlin and differential elongation of hair-cell stereociliaQ28593953
Association of cadherin 23 with polygenic inheritance and genetic modification of sensorineural hearing lossQ30481606
Map Manager QTX, cross-platform software for genetic mappingQ31030142
Ahl2, a second locus affecting age-related hearing loss in miceQ33820990
A nuclear-mitochondrial DNA interaction affecting hearing impairment in miceQ33821006
Modifier genes of hereditary hearing lossQ34029118
Beethoven, a mouse model for dominant, progressive hearing loss DFNA36.Q34114643
Auditory neuropathyQ34386008
Genetic modifiers of vision and hearingQ34641632
Human Nonsyndromic Sensorineural DeafnessQ35550640
Genetic insights into the morphogenesis of inner ear hair cells.Q35813847
Bioinformatics toolbox for narrowing rodent quantitative trait lociQ36286902
Localization of the bronx waltzer (bv) deafness gene to mouse chromosome 5.Q42445066
P433issue4
P407language of work or nameEnglishQ1860
P921main subjecthearing lossQ16035842
quantitative trait locusQ853421
P304page(s)2111-2119
P577publication date2006-04-28
P1433published inGeneticsQ3100575
P1476titleMultiple quantitative trait loci modify cochlear hair cell degeneration in the Beethoven (Tmc1Bth) mouse model of progressive hearing loss DFNA36.
P478volume173

Reverse relations

cites work (P2860)
Q36239574A QTL on Chr 5 modifies hearing loss associated with the fascin-2 variant of DBA/2J mice
Q90240470A Tmc1 mutation reduces calcium permeability and expression of mechanoelectrical transduction channels in cochlear hair cells
Q30482720A locus on distal chromosome 11 (ahl8) and its interaction with Cdh23 ahl underlie the early onset, age-related hearing loss of DBA/2J mice
Q35297950A modifier gene alleviates hypothyroidism-induced hearing impairment in Pou1f1dw dwarf mice
Q28505277A noncoding point mutation of Zeb1 causes multiple developmental malformations and obesity in Twirler mice
Q36200344Amino acid 572 in TMC1: hot spot or critical functional residue for dominant mutations causing hearing impairment
Q49914916Co-deficiency of Lysosomal Mucolipins 3 and 1 in Cochlear Hair Cells Diminishes Outer Hair Cell Longevity and Accelerates Age-Related Hearing Loss.
Q48429300Development of distortion product otoacoustic emissions in C57BL/6J mice
Q46978889Dietary thyroid hormone replacement ameliorates hearing deficits in hypothyroid mice
Q28511525Disruption of fibroblast growth factor receptor 3 signaling results in defects in cellular differentiation, neuronal patterning, and hearing impairment
Q30469465Genetic background of Prop1(df) mutants provides remarkable protection against hypothyroidism-induced hearing impairment
Q30464765Genome-wide linkage analyses identify Hfhl1 and Hfhl3 with frequency-specific effects on the hearing spectrum of NIH Swiss mice
Q30474049High-frequency sensorineural hearing loss and its underlying genetics (Hfhl1 and Hfhl2) in NIH Swiss mice
Q50436365Hydrogen in drinking water attenuates noise-induced hearing loss in guinea pigs
Q37144696Hypo-functional SLC26A4 variants associated with nonsyndromic hearing loss and enlargement of the vestibular aqueduct: genotype-phenotype correlation or coincidental polymorphisms?
Q34689630Identities, frequencies and origins of TMC1 mutations causing DFNB7/B11 deafness in Pakistan
Q24634356Mechanotransduction in mouse inner ear hair cells requires transmembrane channel-like genes
Q35485037Mouse model of enlarged vestibular aqueducts defines temporal requirement of Slc26a4 expression for hearing acquisition
Q34250259Mutations of TMC1 cause deafness by disrupting mechanoelectrical transduction
Q37087936Quiet as a mouse: dissecting the molecular and genetic basis of hearing
Q37004981RNA Interference Prevents Autosomal-Dominant Hearing Loss.
Q30410497Slc26a4-insufficiency causes fluctuating hearing loss and stria vascularis dysfunction
Q27329412Stereocilia-staircase spacing is influenced by myosin III motors and their cargos espin-1 and espin-like
Q91241233Targeted Allele Suppression Prevents Progressive Hearing Loss in the Mature Murine Model of Human TMC1 Deafness
Q58783095Tmc2 expression partially restores auditory function in a mouse model of DFNB7/B11 deafness caused by loss of Tmc1 function
Q34807434Transmembrane channel-like (TMC) genes are required for auditory and vestibular mechanosensation

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