Age-associated defects in EphA2 signaling impair the migration of human cardiac progenitor cells

scientific article

Age-associated defects in EphA2 signaling impair the migration of human cardiac progenitor cells is …
instance of (P31):
scholarly articleQ13442814
retracted paperQ45182324

External links are
P356DOI10.1161/CIRCULATIONAHA.113.004698
P932PMC publication ID3888551
P698PubMed publication ID24141256

P50authorAnnarosa LeriQ19863983
Piero AnversaQ3903152
Jan KajsturaQ57391856
Marcello RotaQ57392184
Polina GoichbergQ57392242
P2093author name stringAnnarosa Leri
Jan Kajstura
Marcello Rota
Ramaswamy Kannappan
Yingnan Bai
Fumihiro Sanada
Sergio Signore
Andrea Sorrentino
Maria Cimini
Polina Goichberg
P2860cites workLoss of caveolin-1 polarity impedes endothelial cell polarization and directional movementQ23909883
Eph/ephrin molecules--a hub for signaling and endocytosisQ24611588
The ephrin A1-EphA2 system promotes cardiac stem cell migration after infarctionQ42739752
A direct role for Met endocytosis in tumorigenesis.Q42809894
EphA4 is localized in clathrin-coated and synaptic vesicles in adult mouse brainQ43196398
Myocyte turnover in the aging human heartQ43415029
Loss of functional caveolae during senescence of human fibroblastsQ43553575
Cardiac stem cell and myocyte aging, heart failure, and insulin-like growth factor-1 overexpression.Q51010411
Peroxiredoxin II is an essential antioxidant enzyme that prevents the oxidative inactivation of VEGF receptor-2 in vascular endothelial cells.Q53398020
Loss of functional caveolae during senescence of human fibroblastsQ57351467
Cardiac Stem Cells Possess Growth Factor-Receptor Systems That After Activation Regenerate the Infarcted Myocardium, Improving Ventricular Function and Long-Term SurvivalQ57395179
EphB receptors coordinate migration and proliferation in the intestinal stem cell nicheQ60721106
Senescence and death of primitive cells and myocytes lead to premature cardiac aging and heart failureQ73906111
Signalling the end of the lineQ83793527
Role of cardiac stem cells in cardiac pathophysiology: a paradigm shift in human myocardial biologyQ26858965
Endosome maturationQ26992067
Oxidants, oxidative stress and the biology of ageingQ28131725
Activation of cardiac progenitor cells reverses the failing heart senescent phenotype and prolongs lifespanQ28566303
Spatial regulation of VEGF receptor endocytosis in angiogenesisQ28585752
EphB receptors regulate stem/progenitor cell proliferation, migration, and polarity during hippocampal neurogenesisQ28591772
Dynasore, a cell-permeable inhibitor of dynaminQ29619881
Intracoronary cardiosphere-derived cells for heart regeneration after myocardial infarction (CADUCEUS): a prospective, randomised phase 1 trialQ29620043
RETRACTED: Cardiac stem cells in patients with ischaemic cardiomyopathy (SCIPIO): initial results of a randomised phase 1 trialQ29620044
An inside view: VEGF receptor trafficking and signalingQ33682832
DNA-SCARS: distinct nuclear structures that sustain damage-induced senescence growth arrest and inflammatory cytokine secretionQ33759285
Stem cells in the dog heart are self-renewing, clonogenic, and multipotent and regenerate infarcted myocardium, improving cardiac functionQ33863225
Effects of age and heart failure on human cardiac stem cell functionQ33942627
Eph receptors and ephrins in cancer: bidirectional signalling and beyondQ34021365
Cellular senescence and the senescent secretory phenotype: therapeutic opportunitiesQ34035882
Flow cytometry and FISH to measure the average length of telomeres (flow FISH).Q34615436
Stem cell niches in the adult mouse heartQ34657903
The redox stress hypothesis of agingQ35705418
Eph/ephrin signaling in morphogenesis, neural development and plasticity.Q35885665
Human cardiac stem cellsQ35956924
Administration of cardiac stem cells in patients with ischemic cardiomyopathy: the SCIPIO trial: surgical aspects and interim analysis of myocardial function and viability by magnetic resonanceQ36252910
Regenerating new heart with stem cellsQ36497191
Assessing cell and organ senescence biomarkersQ36776292
Mechanisms that regulate stem cell aging and life spanQ36810649
Clonality of mouse and human cardiomyogenesis in vivoQ37385968
Endosomes: a legitimate platform for the signaling trainQ37394435
Cellular senescence, ageing and diseaseQ37398698
A model for phospho-caveolin-1-driven turnover of focal adhesions.Q37800338
Endocytosis and signalingQ37862859
The role of endocytosis in activating and regulating signal transductionQ37960345
Eph-dependent cell-cell adhesion and segregation in development and cancer.Q37971902
Concepts and consequences of Eph receptor clusteringQ37977285
Caveolin-1: role in cell signalingQ37992927
Eph/Ephrin signaling in injury and inflammationQ38047589
Caveolin-1 is required for signaling and membrane targeting of EphB1 receptor tyrosine kinaseQ40275557
Anthracycline cardiomyopathy is mediated by depletion of the cardiac stem cell pool and is rescued by restoration of progenitor cell functionQ41883542
Endocytosis of EphA receptors is essential for the proper development of the retinocollicular topographic map.Q42739460
P433issue20
P407language of work or nameEnglishQ1860
P304page(s)2211-2223
P577publication date2013-10-18
P1433published inCirculationQ578091
P1476titleAge-associated defects in EphA2 signaling impair the migration of human cardiac progenitor cells
P478volume128

Reverse relations

cites work (P2860)
Q42007631A Novel Class of Human Cardiac Stem Cells
Q36065239Accumulation of Mitochondrial DNA Mutations Disrupts Cardiac Progenitor Cell Function and Reduces Survival.
Q40095672Activation of EphA4 and EphB2 Reverse Signaling Restores the Age-Associated Reduction of Self-Renewal, Migration, and Actin Turnover in Human Tendon Stem/Progenitor Cells.
Q38596695Aging Effects on Cardiac Progenitor Cell Physiology
Q34552442Aging disrupts cell subpopulation dynamics and diminishes the function of mesenchymal stem cells
Q91418946Assessing Stem Cell DNA Integrity for Cardiac Cell Therapy
Q51751360Beyond cardiomyocyte loss: Role of Notch in cardiac aging.
Q89495332Biology of Tendon Stem Cells and Tendon in Aging
Q90199537Bioreactor-based 3D human myocardial ischemia/reperfusion in vitro model: a novel tool to unveil key paracrine factors upon acute myocardial infarction
Q35695769Cardiac aging - Getting to the stem of the problem.
Q26825051Cardiac stem cells: biology and clinical applications
Q41341645Combined Analysis of Endothelial, Hematopoietic, and Mesenchymal Stem Cell Compartments Shows Simultaneous but Independent Effects of Age and Heart Disease.
Q39390326Concise Review: Challenges in Regenerating the Diabetic Heart: A Comprehensive Review
Q39107914Conformational transitions and interactions underlying the function of membrane embedded receptor protein kinases
Q38840851Current Understanding of the Pathways Involved in Adult Stem and Progenitor Cell Migration for Tissue Homeostasis and Repair
Q38652827Decline in cellular function of aged mouse c-kit+ cardiac progenitor cells.
Q38257853Eph receptors and ephrins: therapeutic opportunities
Q46339083EphB2 signaling-mediated Sirt3 expression reduces MSC senescence by maintaining mitochondrial ROS homeostasis
Q54179932Epigenome-wide association study reveals differential DNA methylation in individuals with a history of myocardial infarction.
Q90735653Expression of Concern
Q95387984Expression of Concern
Q53085931Heart factory or fiction?: cardiac progenitor cells and regeneration.
Q53125918Long noncoding RNA H19 mediates melatonin inhibition of premature senescence of c-kit(+) cardiac progenitor cells by promoting miR-675.
Q37574010Predicting the future with stem cells
Q37505199Rejuvenating the senescent heart
Q45035654Remodeling the Human Adult Stem Cell Niche for Regenerative Medicine Applications
Q49572317Rescue plan for Achilles: Therapeutics steering the fate and functions of stem cells in tendon wound healing
Q58571967Single-Cell Transcriptomics of Human Mesenchymal Stem Cells Reveal Age-Related Cellular Subpopulation Depletion and Impaired Regenerative Function
Q39534918Stimulatory Effects of Mesenchymal Stem Cells on cKit+ Cardiac Stem Cells Are Mediated by SDF1/CXCR4 and SCF/cKit Signaling Pathways
Q36665462miR-204 downregulates EphB2 in aging mouse hippocampal neurons
Q33809750p53 Modulates the Fate of Cardiac Progenitor Cells Ex Vivo and in the Diabetic Heart In Vivo