Next-generation in situ hybridization chain reaction: higher gain, lower cost, greater durability

scientific article

Next-generation in situ hybridization chain reaction: higher gain, lower cost, greater durability is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1021/NN405717P
P932PMC publication ID4046802
P698PubMed publication ID24712299
P5875ResearchGate publication ID261514332

P50authorNiles A. PierceQ7037041
P2093author name stringNiles A Pierce
Harry M T Choi
Victor A Beck
P2860cites workA branched DNA signal amplification assay for quantification of nucleic acid targets below 100 molecules/mlQ24545015
Paradigms for computational nucleic acid designQ24613802
Two-color, rolling-circle amplification on antibody microarrays for sensitive, multiplexed serum-protein measurementsQ24791680
Method for multiplex cellular detection of mRNAs using quantum dot fluorescent in situ hybridizationQ24813897
A DNA-fuelled molecular machine made of DNAQ28144136
Formation and detection of RNA-DNA hybrid molecules in cytological preparationsQ28247194
DNA based identification of medicinal materials in Chinese patent medicinesQ28710364
Appendix G: In Situ Hybridization: An Improved Whole-Mount Method for Xenopus EmbryosQ29620084
Amplification methods to increase the sensitivity of in situ hybridization: play card(s).Q33534710
Nucleic acid sequence design via efficient ensemble defect optimizationQ34131851
Single-cell gene expression profilingQ74572633
Real-time hybridization chain reactionQ81341399
In situ genotyping individual DNA molecules by target-primed rolling-circle amplification of padlock probesQ81554465
Pyrene-excimer probes based on the hybridization chain reaction for the detection of nucleic acids in complex biological fluidsQ82871189
Amplified detection of DNA through the enzyme-free autonomous assembly of hemin/G-quadruplex DNAzyme nanowiresQ83227565
Hybridization chain reaction-based aptameric system for the highly selective and sensitive detection of proteinQ83408684
An electrochemical aptasensor based on hybridization chain reaction with enzyme-signal amplification for interferon-gamma detectionQ84105454
DNA-based hybridization chain reaction for amplified bioelectronic signal and ultrasensitive detection of proteinsQ84221762
A self-assembled DNA nanostructure-amplified quartz crystal microbalance with dissipation biosensing platform for nucleic acidsQ84234839
In situ hybridization chain reaction amplification for universal and highly sensitive electrochemiluminescent detection of DNAQ84876733
Amplified analysis of DNA by the autonomous assembly of polymers consisting of DNAzyme wiresQ85006039
Coupling two different nucleic acid circuits in an enzyme-free amplifierQ85375684
Nanogold-based bio-bar codes for label-free immunosensing of proteins coupling with an in situ DNA-based hybridization chain reactionQ85419599
Graphene surface-anchored fluorescence sensor for sensitive detection of microRNA coupled with enzyme-free signal amplification of hybridization chain reactionQ85534562
Programmable imaging amplification via nanoparticle-initiated DNA polymerizationQ87023329
Ultrasensitive electrochemical DNA detection based on dual amplification of circular strand-displacement polymerase reaction and hybridization chain reactionQ95817625
Combining nucleic acid amplification and detectionQ34134912
Dynamic DNA nanotechnology using strand-displacement reactionsQ34160407
Multiplex detection of RNA expression in Drosophila embryosQ34339201
Recent developments in signal amplification methods for in situ hybridizationQ34531678
Imaging individual mRNA molecules using multiple singly labeled probesQ34833213
Immuno-hybridization chain reaction for enhancing detection of individual cytokine-secreting human peripheral mononuclear cellsQ35220317
Gene expression profiling in single cells within tissueQ35991125
Isoform-specific 3'-untranslated sequences sort alpha-cardiac and beta-cytoplasmic actin messenger RNAs to different cytoplasmic compartmentsQ36233363
Oligonucleotide probes for RNA-targeted fluorescence in situ hybridizationQ36716921
Self-assembled, aptamer-tethered DNA nanotrains for targeted transport of molecular drugs in cancer theranostics.Q36855129
Building fluorescent DNA nanodevices on target living cell surfacesQ37128176
Triggered amplification by hybridization chain reactionQ37593751
Amperometric aptasensor for thrombin detection using enzyme-mediated direct electrochemistry and DNA-based signal amplification strategyQ38313897
A novel electrochemical aptasensor for thrombin detection based on the hybridization chain reaction with hemin/G-quadruplex DNAzyme-signal amplificationQ38315033
Hybridization chain reaction engineered DNA nanopolylinker for amplified electrochemical sensing of biomarkersQ39386396
Visualization of single RNA transcripts in situQ39465222
In situ detection and genotyping of individual mRNA moleculesQ39716147
In situ detection of messenger RNA using digoxigenin-labeled oligonucleotides and rolling circle amplificationQ40797581
Programmable in situ amplification for multiplexed imaging of mRNA expressionQ42040352
Electrochemical immunoassay for thyroxine detection using cascade catalysis as signal amplified enhancer and multi-functionalized magnetic graphene sphere as signal tag.Q43475626
NUPACK: Analysis and design of nucleic acid systemsQ44438781
Enzyme-free colorimetric detection of DNA by using gold nanoparticles and hybridization chain reaction amplificationQ46220936
Manganese porphyrin-dsDNA complex: a mimicking enzyme for highly efficient bioanalysisQ46661262
Kinetically grafting G-quadruplexes onto DNA nanostructures for structure and function encoding via a DNA machineQ47359748
FISHing for chick genes: Triple-label whole-mount fluorescence in situ hybridization detects simultaneous and overlapping gene expression in avian embryos.Q48020252
Detection of two different mRNAs in a single section by dual in situ hybridization: a comparison between colorimetric and fluorescent detectionQ48270167
Robert Feulgen Prize Lecture 1999. Detection and amplification systems for sensitive, multiple-target DNA and RNA in situ hybridization: looking inside cells with a spectrum of colorsQ48376906
Enzyme-free and ultrasensitive electrochemical detection of nucleic acids by target catalyzed hairpin assembly followed with hybridization chain reactionQ50231824
Nanogold-functionalized DNAzyme concatamers with redox-active intercalators for quadruple signal amplification of electrochemical immunoassayQ50236305
Comparison of in-situ hybridization, direct and indirect in-situ PCR as well as tyramide signal amplification for the detection of HPV.Q50519722
A cytometric bead assay for sensitive DNA detection based on enzyme-free signal amplification of hybridization chain reaction.Q50872417
Homogeneous bioluminescence detection of biomolecules using target-triggered hybridization chain reaction-mediated ligation without luciferase label.Q50907499
Amplified detection of nucleic acid by G-quadruplex based hybridization chain reaction.Q51539045
Hybridization chain reaction-based instantaneous derivatization technology for chemiluminescence detection of specific DNA sequences.Q51823406
Sensitive electrochemical monitoring of nucleic acids coupling DNA nanostructures with hybridization chain reaction.Q51873172
ProbeDesigner: for the design of probesets for branched DNA (bDNA) signal amplification assays.Q52212330
Double labeling with fluorescence in situ hybridization in Drosophila whole-mount embryos.Q52563090
DNAzyme-based magneto-controlled electronic switch for picomolar detection of lead (II) coupling with DNA-based hybridization chain reaction.Q53118125
Branch migration mediated DNA labeling and cloning.Q54723606
Fluorescence detection for DNA using hybridization chain reaction with enzyme-amplificationQ64387175
Improved localization of fluorescent tyramides for fluorescence in situ hybridization using dextran sulfate and polyvinyl alcoholQ71001719
Comparison of immunologic amplification vs enzymatic deposition of fluorochrome-conjugated tyramide as detection systems for FISHQ73157371
Single-copy gene detection using branched DNA (bDNA) in situ hybridizationQ73758628
P433issue5
P407language of work or nameEnglishQ1860
P304page(s)4284-4294
P577publication date2014-04-08
P1433published inACS NanoQ2819067
P1476titleNext-generation in situ hybridization chain reaction: higher gain, lower cost, greater durability
P478volume8

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cites work (P2860)
Q91125172"Second-generation" fluorogenic RNA-based sensors
Q33731183A Fluorescence in Situ Hybridization Method To Quantify mRNA Translation by Visualizing Ribosome-mRNA Interactions in Single Cells
Q50886047A Nanobiosensor Based on Fluorescent DNA-Hosted Silver Nanocluster and HCR Amplification for Detection of MicroRNA Involved in Progression of Multiple Sclerosis.
Q90390942A Pandas complex adapted for piRNA-guided transcriptional silencing and heterochromatin formation
Q68472811A hybridization-chain-reaction-based method for amplifying immunosignals
Q38813167A modified protocol for the detection of three different mRNAs with a new-generation in situ hybridization chain reaction on frozen sections
Q58070911A review of microscopy and comparative molecular-based methods to characterize “Plastisphere” communities
Q50917477A supersandwich fluorescence in situ hybridization strategy for highly sensitive and selective mRNA imaging in tumor cells.
Q90699389A technical review and guide to RNA fluorescence in situ hybridization
Q37120491A transcription factor network controls cell migration and fate decisions in the developing zebrafish pineal complex.
Q89494769Accelerating DNA-Based Computing on a Supramolecular Polymer
Q35876078Analysis of dynamic changes in retinoid-induced transcription and epigenetic profiles of murine Hox clusters in ES cells
Q38818221Approaches towards molecular amplification for sensing
Q89256818Assessing Individual Neuronal Activity Across the Intact Brain: Using Hybridization Chain Reaction (HCR) to Detect Arc mRNA Localized to the Nucleus in Volumes of Cleared Brain Tissue
Q48262342Automated cell-type classification in intact tissues by single-cell molecular profiling.
Q64106701Avian Primordial Germ Cells Contribute to and Interact With the Extracellular Matrix During Early Migration
Q90862414Branched hybridization chain reaction-using highly dimensional DNA nanostructures for label-free, reagent-less, multiplexed molecular diagnostics
Q47978451CAGE: Chromatin Analogous Gene Expression.
Q57477017Chimeric padlock and iLock probes for increased efficiency of targeted RNA detection
Q93002013ClampFISH detects individual nucleic acid molecules using click chemistry-based amplification
Q26744838Clearing and Labeling Techniques for Large-Scale Biological Tissues
Q92669298Combined microRNA and mRNA detection in mammalian retinas by in situ hybridization chain reaction
Q41042643Constructing real-time, wash-free, and reiterative sensors for cell surface proteins using binding-induced dynamic DNA assembly.
Q53831839Construction of an autonomously concatenated hybridization chain reaction for signal amplification and intracellular imaging.
Q59357771Cycling of Rational Hybridization Chain Reaction To Enable Enzyme-Free DNA-Based Clinical Diagnosis
Q47724796DAN (NBL1) promotes collective neural crest migration by restraining uncontrolled invasion.
Q38578352DNA nanotechnology from the test tube to the cell.
Q64052002DNA-templated synthesis of biomimetic cell wall for nanoencapsulation and protection of mammalian cells
Q90612546Designed and Evolved Nucleic Acid Nanotechnology: Contrast and Complementarity
Q46603674Detection and signal amplification in zebrafish RNA FISH.
Q55172529Detection of Sub-fM DNA with Target Recycling and Self-Assembly Amplification on Graphene Field-Effect Biosensors.
Q61908055Digestion-ligation-only Hi-C is an efficient and cost-effective method for chromosome conformation capture
Q97636238Discovery and evolution of RNA and XNA reverse transcriptase function and fidelity
Q98464612Encoding Method of Single-cell Spatial Transcriptomics Sequencing
Q37210984Engineering a robust DNA split proximity circuit with minimized circuit leakage
Q47327532Engineering high-performance hairpin stacking circuits for logic gate operation and highly sensitive biosensing assay of microRNA.
Q40617768Enzyme-free amplification and detection of bovine viral diarrhea virus RNA using hybridization chain reaction and gold nanoparticles.
Q39458627Enzyme-free, signal-amplified nucleic acid circuits for biosensing and bioimaging analysis
Q67471734Expansion Microscopy: Protocols for Imaging Proteins and RNA in Cells and Tissues.
Q94478532Expansion microscopy of C. elegans
Q47188643Expansion microscopy: development and neuroscience applications
Q64357579Expansion microscopy: principles and uses in biological research
Q100635895Experimentally-validated correlation analysis reveals new anaerobic methane oxidation partnerships with consortium-level heterogeneity in diazotrophy
Q37292246Exposing the Three-Dimensional Biogeography and Metabolic States of Pathogens in Cystic Fibrosis Sputum via Hydrogel Embedding, Clearing, and rRNA Labeling
Q38890789Extracting structural and functional features of widely distributed biological circuits with single cell resolution via tissue clearing and delivery vectors
Q38753472Fish-on-a-chip: microfluidics for zebrafish research
Q90162254Fluorescence In Situ Imaging of Dendritic RNAs at Single-Molecule Resolution
Q58862336From “Cellular” RNA to “Smart” RNA: Multiple Roles of RNA in Genome Stability and Beyond
Q39780720Gene networks and developmental context: the importance of understanding complex gene expression patterns in evolution
Q99545325Global landscape of phenazine biosynthesis and biodegradation reveals species-specific colonization patterns in agricultural soils and crop microbiomes
Q90598602Grafting from a Hybrid DNA-Covalent Polymer by the Hybridization Chain Reaction
Q42657178High resolution, high speed, long working distance, large field of view confocal fluorescence microscope
Q92916702High-fidelity amplified FISH for the detection and allelic discrimination of single mRNA molecules
Q48016302Hybridization Chain Reaction for Direct mRNA Detection Without Nucleic Acid Purification
Q38675885Hybridization chain reaction: a versatile molecular tool for biosensing, bioimaging, and biomedicine
Q46723745Hyperbranched Hybridization Chain Reaction for Triggered Signal Amplification and Concatenated Logic Circuits
Q45943501Identification of a neural crest stem cell niche by Spatial Genomic Analysis.
Q36989398Identifying the Target Cells and Mechanisms of Merkel Cell Polyomavirus Infection
Q39424515Illuminating Messengers: An Update and Outlook on RNA Visualization in Bacteria
Q90226764Imaging the Life and Death of mRNAs in Single Cells
Q54064678In Situ Single-Molecule RNA Genotyping Using Padlock Probes and Rolling Circle Amplification.
Q42377271In Situ Transcription Profiling of Single Cells Reveals Spatial Organization of Cells in the Mouse Hippocampus
Q51383497In situ DNA-hybridization chain reaction (HCR): a facilitated in situ HCR system for the detection of environmental microorganisms.
Q91826268Investigating Nrg1 Signaling in the Regenerating Axolotl Spinal Cord Using Multiplexed FISH
Q36196829Key Structural Elements of Unsymmetrical Cyanine Dyes for Highly Sensitive Fluorescence Turn-On DNA Probes.
Q46205727Live Cell Imaging of Endogenous mRNA Using RNA-Based Fluorescence "Turn-On" Probe.
Q38690004Low picomolar, instrument-free visual detection of mercury and silver ions using low-cost programmable nanoprobes
Q39323495Mapping a multiplexed zoo of mRNA expression
Q91871152Merkel Cell Polyomavirus Infection and Detection
Q39042180Methods for the analysis of early oogenesis in Zebrafish
Q59807837Modeling craniofacial development reveals spatiotemporal constraints on robust patterning of the mandibular arch
Q47193224Multidimensional quantitative analysis of mRNA expression within intact vertebrate embryos.
Q36643896Multiplexed Intact-Tissue Transcriptional Analysis at Cellular Resolution
Q64986517Multiplexed detection of RNA using MERFISH and branched DNA amplification.
Q37228866Multiplexed miRNA northern blots via hybridization chain reaction
Q37136338Nanoscale imaging of RNA with expansion microscopy
Q38364195Neural crest migration: trailblazing ahead
Q58563419Neuromesodermal progenitors are a conserved source of spinal cord with divergent growth dynamics
Q36791918Noise modulation in retinoic acid signaling sharpens segmental boundaries of gene expression in the embryonic zebrafish hindbrain
Q50880214Non-Covalent Fluorescent Labeling of Hairpin DNA Probe Coupled with Hybridization Chain Reaction for Sensitive DNA Detection.
Q27345399Oocyte Polarization Is Coupled to the Chromosomal Bouquet, a Conserved Polarized Nuclear Configuration in Meiosis
Q93078977Opportunities, Challenges, and Prospects in Electrochemical Biosensing of Circulating Tumor DNA and its Specific Features
Q91432430Optimizing Tissue Preservation for High-Resolution Confocal Imaging of Single-Molecule RNA-FISH
Q60960609Overview of DNA Self-Assembling: Progresses in Biomedical Applications
Q47972844Padlock Probes to Detect Single Nucleotide Polymorphisms
Q46713018Pnrc2 regulates 3'UTR-mediated decay of segmentation clock-associated transcripts during zebrafish segmentation
Q57798905Preparation of plant tissue to enable Spatial Transcriptomics profiling using barcoded microarrays
Q46523525Profiling the transcriptome with RNA SPOTs
Q64274131Programmable intracellular DNA biocomputing circuits for reliable cell recognitions
Q64903283Protection of tissue physicochemical properties using polyfunctional crosslinkers.
Q47810127Proximity aptasensor for protein detection based on an enzyme-free amplification strategy
Q35660926Proximity-dependent initiation of hybridization chain reaction
Q36409638Q&A: Expansion microscopy
Q42364008Q&A: How can advances in tissue clearing and optogenetics contribute to our understanding of normal and diseased biology?
Q90984649Quantitative analysis reveals genotype- and domain- specific differences between mRNA and protein expression of segmentation genes in Drosophila
Q40076081Rapid Visual Screening and Programmable Subtype Classification of Ebola Virus Biomarkers
Q51496579Rational design of hybridization chain reaction monomers for robust signal amplification.
Q36497231Reck enables cerebrovascular development by promoting canonical Wnt signaling.
Q45227051Reversible Loading of Nanoscale Elements on a Multicomponent Supramolecular Polymer System by Using DNA Strand Displacement.
Q59804254RollFISH achieves robust quantification of single-molecule RNA biomarkers in paraffin-embedded tumor tissue samples
Q92173127SABER amplifies FISH: enhanced multiplexed imaging of RNA and DNA in cells and tissues
Q38682545Signal Amplification Technologies for the Detection of Nucleic Acids: from Cell-Free Analysis to Live-Cell Imaging
Q47242554Simultaneous Multiplexed Imaging of mRNA and Proteins with Subcellular Resolution in Breast Cancer Tissue Samples by Mass Cytometry.
Q37217389Single-molecule RNA detection at depth by hybridization chain reaction and tissue hydrogel embedding and clearing
Q64939484Single-step multivalent capture assay for nucleic acid detection with dual-affinity regulation using mutation inhibition and allosteric activation.
Q27304985Spatio-Temporal Differences in Dystrophin Dynamics at mRNA and Protein Levels Revealed by a Novel FlipTrap Line
Q94483876Stability and nuclear localization of yeast telomerase depend on protein components of RNase P/MRP
Q38663510Stochasticity in the enterococcal sex pheromone response revealed by quantitative analysis of transcription in single cells
Q37393955Strand-Exchange Nucleic Acid Circuitry with Enhanced Thermo-and Structure- Buffering Abilities Turns Gene Diagnostics Ultra-Reliable and Environmental Compatible
Q28081247Strength in numbers: quantitative single-molecule RNA detection assays
Q41074715Sub-100-nm metafluorophores with digitally tunable optical properties self-assembled from DNA.
Q38712384The development of nanostructure assisted isothermal amplification in biosensors
Q55347186The importance of thermodynamics for molecular systems, and the importance of molecular systems for thermodynamics.
Q51052882The inhibition effect of starch nanoparticles on tyrosinase activity and its mechanism.
Q48031984The promise of spatial transcriptomics for neuroscience in the era of molecular cell typing.
Q57653395Third-generation hybridization chain reaction: multiplexed, quantitative, sensitive, versatile, robust
Q96816542Three-dimensional single-cell imaging for the analysis of RNA and protein expression in intact tumour biopsies
Q90607006Transcriptomics reveals complex kinetics of dorsal-ventral patterning gene expression in the mandibular arch
Q88938280Ultrafast neuronal imaging of dopamine dynamics with designed genetically encoded sensors
Q37690342Ultrasensitive colorimetric detection of circulating tumor DNA using hybridization chain reaction and the pivot of triplex DNA.
Q36000323Use of Hybridization Chain Reaction-Fluorescent In Situ Hybridization To Track Gene Expression by Both Partners during Initiation of Symbiosis
Q58089223Whole-Brain Analysis of Cells and Circuits by Tissue Clearing and Light-Sheet Microscopy
Q37029369Whole-body tissue stabilization and selective extractions via tissue-hydrogel hybrids for high-resolution intact circuit mapping and phenotyping
Q38947544cis-Regulatory control of the initial neurogenic pattern of onecut gene expression in the sea urchin embryo
Q83230772piRNA-guided co-transcriptional silencing coopts nuclear export factors

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