Pharmacological rescue of cortical synaptic and network potentiation in a mouse model for fragile X syndrome

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Pharmacological rescue of cortical synaptic and network potentiation in a mouse model for fragile X syndrome is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1027730902
P356DOI10.1038/NPP.2014.44
P932PMC publication ID4059905
P698PubMed publication ID24553731
P5875ResearchGate publication ID260271385

P2093author name stringTao Chen
Min Zhuo
Giannina Descalzi
Kohei Koga
Qian Song
Yun-Qing Li
Ming-Gang Liu
Jing-Shan Lu
P2860cites workAltered synaptic plasticity in a mouse model of fragile X mental retardationQ24530695
Metabotropic glutamate receptors trigger postsynaptic protein synthesisQ24561912
Abnormal dendritic spines in fragile X knockout mice: maturation and pruning deficitsQ24657867
Long-term potentiation in the anterior cingulate cortex and chronic painQ26865078
The pathophysiology of fragile X (and what it teaches us about synapses)Q27010675
A decade of molecular studies of fragile X syndromeQ28203140
The fragile X syndrome protein FMRP associates with BC1 RNA and regulates the translation of specific mRNAs at synapsesQ28208647
From mRNP trafficking to spine dysmorphogenesis: the roots of fragile X syndromeQ28247567
Deletion of FMR1 in Purkinje cells enhances parallel fiber LTD, enlarges spines, and attenuates cerebellar eyelid conditioning in Fragile X syndromeQ28512868
Roles of NMDA NR2B subtype receptor in prefrontal long-term potentiation and contextual fear memoryQ28568550
Subunit-specific rules governing AMPA receptor trafficking to synapses in hippocampal pyramidal neuronsQ28579011
Elongation factor 2 and fragile X mental retardation protein control the dynamic translation of Arc/Arg3.1 essential for mGluR-LTDQ28585633
The molecular biology of memory storage: a dialogue between genes and synapsesQ29547845
The mGluR theory of fragile X mental retardationQ29615060
Ras signaling mechanisms underlying impaired GluR1-dependent plasticity associated with fragile X syndromeQ30441120
Bidirectional regulation of dendritic voltage-gated potassium channels by the fragile X mental retardation proteinQ30460772
Elevated glycogen synthase kinase-3 activity in Fragile X mice: key metabolic regulator with evidence for treatment potential.Q30488395
Lithium ameliorates altered glycogen synthase kinase-3 and behavior in a mouse model of fragile X syndrome.Q33607288
Silent synapses and the emergence of a postsynaptic mechanism for LTP.Q33641298
Expression mechanisms underlying NMDA receptor-dependent long-term potentiationQ33691522
Genetic enhancement of trace fear memory and cingulate potentiation in mice overexpressing Ca2+/calmodulin-dependent protein kinase IV.Q50795516
Fragile X mouse: strain effects of knockout phenotype and evidence suggesting deficient amygdala function.Q51083891
Long-term potentiation in the hippocampus of fragile X knockout miceQ57828486
Role for Rapid Dendritic Protein Synthesis in Hippocampal mGluR-Dependent Long-Term DepressionQ60141744
Synaptic potentiation of dual-component excitatory postsynaptic currents in the rat hippocampusQ72192518
Loss of the fragile X mental retardation protein decouples metabotropic glutamate receptor dependent priming of long-term potentiation from protein synthesisQ34108310
Calcium/calmodulin-dependent kinase IV contributes to translation-dependent early synaptic potentiation in the anterior cingulate cortex of adult miceQ34174584
Plasticity of metabotropic glutamate receptor-dependent long-term depression in the anterior cingulate cortex after amputationQ34294210
Activation of postsynaptically silent synapses during pairing-induced LTP in CA1 region of hippocampal sliceQ34311517
Synaptic plasticity, memory and the hippocampus: a neural network approach to causality.Q34727978
The biology of memory: a forty-year perspectiveQ35007945
Long-term potentiation and long-term depression: a clinical perspectiveQ35054973
Introduction. Long-term potentiation and structure of the issueQ35124797
Fusion pore modulation as a presynaptic mechanism contributing to expression of long-term potentiationQ35124807
Synaptic disinhibition during maintenance of long-term potentiation in the CA1 hippocampal subfieldQ35152914
Long-term potentiation in the dentate gyrus of the anaesthetized rat is accompanied by an increase in extracellular glutamate: real-time measurements using a novel dialysis electrodeQ35213510
Inhibition of GSK3β improves hippocampus-dependent learning and rescues neurogenesis in a mouse model of fragile X syndromeQ35674710
A pivotal role of GSK-3 in synaptic plasticity.Q35757839
Absence of metabotropic glutamate receptor-mediated plasticity in the neocortex of fragile X mice.Q35844502
Rapid synaptic potentiation within the anterior cingulate cortex mediates trace fear learningQ36092364
Rapid translation of Arc/Arg3.1 selectively mediates mGluR-dependent LTD through persistent increases in AMPAR endocytosis rateQ36966248
Long-term potentiation of synaptic transmission in the adult mouse insular cortex: multielectrode array recordingsQ37054831
Role for metabotropic glutamate receptor 5 (mGluR5) in the pathogenesis of fragile X syndromeQ37059491
Altered hippocampal synaptic plasticity in the FMR1 gene family knockout mouse modelsQ37190453
Characterization of intracortical synaptic connections in the mouse anterior cingulate cortex using dual patch clamp recordingQ37405850
Predicting aversive events and terminating fear in the mouse anterior cingulate cortex during trace fear conditioning.Q39661854
A decrease in firing threshold observed after induction of the EPSP-spike (E-S) component of long-term potentiation in rat hippocampal slicesQ41230210
Genetic demonstration of a role for PKA in the late phase of LTP and in hippocampus-based long-term memoryQ42435372
Deficits in trace fear memory and long-term potentiation in a mouse model for fragile X syndrome.Q42482484
Open-label treatment trial of lithium to target the underlying defect in fragile X syndromeQ42594453
Fragile X mental retardation protein is required for chemically-induced long-term potentiation of the hippocampus in adult mice.Q43297720
Reduced cortical synaptic plasticity and GluR1 expression associated with fragile X mental retardation protein deficiency.Q43892381
Expression of constitutively active CREB protein facilitates the late phase of long-term potentiation by enhancing synaptic captureQ43917165
Presynaptic enhancement shown by whole-cell recordings of long-term potentiation in hippocampal slicesQ46122085
Brain-derived neurotrophic factor rescues synaptic plasticity in a mouse model of fragile X syndromeQ46145632
Calcium-stimulated adenylyl cyclases required for long-term potentiation in the anterior cingulate cortexQ46573022
Silent synapses during development of thalamocortical inputsQ46721431
The inhibition of glycogen synthase kinase 3beta by a metabotropic glutamate receptor 5 mediated pathway confers neuroprotection to Abeta peptidesQ46796513
Increased threshold for spike-timing-dependent plasticity is caused by unreliable calcium signaling in mice lacking fragile X gene FMR1.Q48158558
Effects of cAMP simulate a late stage of LTP in hippocampal CA1 neuronsQ48267434
Synaptic coexistence of AMPA and NMDA receptors in the rat hippocampus: a postembedding immunogold studyQ48346971
Genetic evidence for adenylyl cyclase 1 as a target for preventing neuronal excitotoxicity mediated by N-methyl-D-aspartate receptors.Q48361521
Cell type and pathway dependence of synaptic AMPA receptor number and variability in the hippocampusQ48377872
Anxiolytic-like effects of the selective metabotropic glutamate receptor 5 antagonist MPEP after its intra-amygdaloid microinjection in three different non-conditioned rat models of anxietyQ48480239
Age-dependent and selective impairment of long-term potentiation in the anterior piriform cortex of mice lacking the fragile X mental retardation protein.Q48732650
Long-term potentiation in Schaffer collateral and commissural systems of the hippocampus: In vitro study in rats pretreated with kainic acidQ48761967
Long-term potentiation in the hippocampus of fragile X knockout miceQ48943824
P4510describes a project that usesImageJQ1659584
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectpharmacologyQ128406
fragile X syndromeQ221472
P304page(s)1955-1967
P577publication date2014-02-20
P1433published inNeuropsychopharmacologyQ2261280
P1476titlePharmacological rescue of cortical synaptic and network potentiation in a mouse model for fragile X syndrome
P478volume39

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cites work (P2860)
Q36708087Acid-sensing ion channel 1a contributes to hippocampal LTP inducibility through multiple mechanisms
Q34346403Adenylyl cyclase subtype 1 is essential for late-phase long term potentiation and spatial propagation of synaptic responses in the anterior cingulate cortex of adult mice
Q41270458Age-Dependent Long-Term Potentiation Deficits in the Prefrontal Cortex of the Fmr1 Knockout Mouse Model of Fragile X Syndrome
Q93103822Anterior insular cortex mediates hyperalgesia induced by chronic pancreatitis in rats
Q30418368Antipurinergic therapy corrects the autism-like features in the Fragile X (Fmr1 knockout) mouse model.
Q64090589Calcitonin gene-related peptide potentiated the excitatory transmission and network propagation in the anterior cingulate cortex of adult mice
Q64097444Calcium-stimulated adenylyl cyclase subtype 1 is required for presynaptic long-term potentiation in the insular cortex of adult mice
Q48665243Differential Adulthood Onset mGlu5 Signaling Saves Prefrontal Function in the Fragile X Mouse.
Q37346949Elevated ERK/p90 ribosomal S6 kinase activity underlies audiogenic seizure susceptibility in fragile X mice
Q26829152Emerging pharmacologic treatment options for fragile X syndrome
Q35218838Functional and structural deficits at accumbens synapses in a mouse model of Fragile X.
Q30713841Impaired cognitive discrimination and discoordination of coupled theta-gamma oscillations in Fmr1 knockout mice
Q55365043Impaired hippocampal representation of place in the Fmr1-knockout mouse model of fragile X syndrome.
Q48343073Impaired presynaptic long-term potentiation in the anterior cingulate cortex of Fmr1 knock-out mice.
Q64972685Loss of Synaptic Tagging in the Anterior Cingulate Cortex after Tail Amputation in Adult Mice.
Q38863874Metabotropic Glutamate Receptor Dependent Cortical Plasticity in Chronic Pain
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Q36141229Molecular mechanisms regulating impaired neurogenesis of fragile X syndrome human embryonic stem cells
Q39157732Neuronal and microglial mechanisms for neuropathic pain in the spinal dorsal horn and anterior cingulate cortex.
Q51730970No requirement of interlukine-1 for long-term potentiation in the anterior cingulate cortex of adult mice.
Q47553088Normal CA1 Place Fields but Discoordinated Network Discharge in a Fmr1-Null Mouse Model of Fragile X Syndrome
Q53422584Of Men and Mice: Modeling the Fragile X Syndrome.
Q34460051Postsynaptic insertion of AMPA receptor onto cortical pyramidal neurons in the anterior cingulate cortex after peripheral nerve injury
Q58706607Reduced synaptic function of Kainate receptors in the insular cortex of Fmr1 Knock-out mice
Q38648021Selective Phosphorylation of AMPA Receptor Contributes to the Network of Long-Term Potentiation in the Anterior Cingulate Cortex.
Q90364879Sex difference in synaptic plasticity in the anterior cingulate cortex of adult mice
Q26745117Synaptic Plasticity, a Prominent Contributor to the Anxiety in Fragile X Syndrome

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