Fission yeast profilin is tailored to facilitate actin assembly by the cytokinesis formin Cdc12.

scientific article

Fission yeast profilin is tailored to facilitate actin assembly by the cytokinesis formin Cdc12. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1091/MBC.E13-05-0281
P932PMC publication ID4294675
P698PubMed publication ID25392301

P50authorJenna R ChristensenQ42290545
P2093author name stringRobert J Keenan
Thomas A Burke
David R Kovar
Andrew J Bestul
Vladimir Sirotkin
Jennifer A Sees
Robert T Carroll
Agnieszka P Grzegorzewska
P2860cites workDifferential remodeling of actin cytoskeleton architecture by profilin isoforms leads to distinct effects on cell migration and invasionQ24303907
Fission yeast Sop2p: a novel and evolutionarily conserved protein that interacts with Arp3p and modulates profilin functionQ24309489
Bni1p, a yeast formin linking cdc42p and the actin cytoskeleton during polarized morphogenesisQ24310527
The proline-rich focal adhesion and microfilament protein VASP is a ligand for profilinsQ24568320
Formins at a glanceQ27009102
Profilin binds proline-rich ligands in two distinct amide backbone orientationsQ27619025
Incompatibility with Formin Cdc12p Prevents Human Profilin from Substituting for Fission Yeast Profilin: INSIGHTS FROM CRYSTAL STRUCTURES OF FISSION YEAST PROFILINQ27652980
Characterization of two classes of small molecule inhibitors of Arp2/3 complexQ27656832
The structure of crystalline profilin-beta-actinQ27732069
Structure of the profilin-poly-L-proline complex involved in morphogenesis and cytoskeletal regulationQ27747144
Structure determination and characterization of Saccharomyces cerevisiae profilinQ27764965
Mutational analysis of yeast profilinQ27931447
Cofilin recruitment and function during actin-mediated endocytosis dictated by actin nucleotide stateQ27936702
In vivo importance of actin nucleotide exchange catalyzed by profilinQ27939378
Crystal structures of a Formin Homology-2 domain reveal a tethered dimer architectureQ28248937
Actin polymerizability is influenced by profilin, a low molecular weight protein in non-muscle cellsQ28254284
Profilin2 contributes to synaptic vesicle exocytosis, neuronal excitability, and novelty-seeking behaviorQ28592417
The many faces of actin: matching assembly factors with cellular structuresQ29620433
Assembly of the cytokinetic contractile ring from a broad band of nodes in fission yeastQ30480451
Regulation and targeting of the fission yeast formin cdc12p in cytokinesisQ30481843
Model of formin-associated actin filament elongationQ37027224
Role of tropomyosin in formin-mediated contractile ring assembly in fission yeastQ37158388
Actin nucleation and elongation factors: mechanisms and interplayQ37164608
Rapid formin-mediated actin-filament elongation is essential for polarized plant cell growthQ37304139
Non-redundant roles for Profilin2 and Profilin1 during vertebrate gastrulationQ37344291
Actin filament nucleation and elongation factors--structure-function relationshipsQ37455891
Review of the mechanism of processive actin filament elongation by forminsQ37491020
Polyproline binding is an essential function of human profilin in yeastQ38325062
cdc12p, a protein required for cytokinesis in fission yeast, is a component of the cell division ring and interacts with profilinQ40897448
The cytokinesis formins from the nematode worm and fission yeast differentially mediate actin filament assemblyQ42120294
Roles of the fission yeast formin for3p in cell polarity, actin cable formation and symmetric cell divisionQ43790544
Formin is a processive motor that requires profilin to accelerate actin assembly and associated ATP hydrolysisQ45126402
Structural basis of actin filament nucleation and processive capping by a formin homology 2 domainQ45213799
Control of the assembly of ATP- and ADP-actin by formins and profilin.Q45345926
Formin differentially utilizes profilin isoforms to rapidly assemble actin filamentsQ46268992
Assembly mechanism of the contractile ring for cytokinesis by fission yeastQ48026763
Arabidopsis profilins are functionally similar to yeast profilins: identification of a vascular bundle-specific profilin and a pollen-specific profilin.Q48061677
Chlamydomonas reinhardtii produces a profilin with unusual biochemical propertiesQ48329493
Stepping into the ring: the SIN takes on contractile ring assembly.Q53433632
Identification of the poly-L-proline-binding site on human profilin.Q54738745
The actin-binding protein profilin binds to PIP2 and inhibits its hydrolysis by phospholipase CQ68454345
Quantitative analysis of the effect of Acanthamoeba profilin on actin filament nucleation and elongationQ70802575
Acanthamoeba profilin interacts with G-actin to increase the rate of exchange of actin-bound adenosine 5'-triphosphateQ71851561
The S. pombe rlc1 gene encodes a putative myosin regulatory light chain that binds the type II myosins myo3p and myo2pQ73167868
Evidence for two interaction regions for phosphatidylinositol(4,5)-bisphosphate on mammalian profilin IQ74404416
Effects of single amino acid substitutions in the actin-binding site on the biological activity of bovine profilin IQ77465501
Rotational movement of the formin mDia1 along the double helical strand of an actin filamentQ82838077
Energetic requirements for processive elongation of actin filaments by FH1FH2-forminsQ30487234
Roles of formin nodes and myosin motor activity in Mid1p-dependent contractile-ring assembly during fission yeast cytokinesis.Q30492328
Characterization of structural and functional domains of the anillin-related protein Mid1p that contribute to cytokinesis in fission yeast.Q30525606
Nonmedially assembled F-actin cables incorporate into the actomyosin ring in fission yeast.Q30528962
Homeostatic actin cytoskeleton networks are regulated by assembly factor competition for monomers.Q30575659
Insertional assembly of actin filament barbed ends in association with formins produces piconewton forcesQ31113561
Role of actin polymerization and actin cables in actin-patch movement in Schizosaccharomyces pombeQ32084012
Laboratory-directed protein evolutionQ33222949
The mammalian profilin isoforms display complementary affinities for PIP2 and proline-rich sequencesQ33886049
Mathematical modeling of endocytic actin patch kinetics in fission yeast: disassembly requires release of actin filament fragmentsQ34063827
Actin dynamics in the contractile ring during cytokinesis in fission yeastQ34147996
Isolation and characterization of fission yeast mutants defective in the assembly and placement of the contractile actin ring.Q34400026
Genetic control of the cell division cycle in the fission yeast Schizosaccharomyces pombeQ34467598
Assembly and architecture of precursor nodes during fission yeast cytokinesisQ34712437
Three's company: the fission yeast actin cytoskeletonQ34776860
Profilin regulates F-actin network homeostasis by favoring formin over Arp2/3 complexQ34945496
Characterization of dip1p reveals a switch in Arp2/3-dependent actin assembly for fission yeast endocytosisQ35062892
The functionally distinct fission yeast formins have specific actin-assembly propertiesQ35340654
Profilin binding to poly-L-proline and actin monomers along with ability to catalyze actin nucleotide exchange is required for viability of fission yeastQ35588789
Determinants of Formin Homology 1 (FH1) domain function in actin filament elongation by forminsQ35801835
The role of profilin complexes in cell motility and other cellular processesQ35861651
The Schizosaccharomyces pombe actin-related protein, Arp3, is a component of the cortical actin cytoskeleton and interacts with profilinQ35915558
Formin proteins: a domain-based approach.Q36160324
Purification of profilin from Saccharomyces cerevisiae and analysis of profilin-deficient cellsQ36222408
The fission yeast cytokinesis formin Cdc12p is a barbed end actin filament capping protein gated by profilinQ36323549
Molecular details of formin-mediated actin assemblyQ36346689
The Schizosaccharomyces pombe cdc3+ gene encodes a profilin essential for cytokinesisQ36534881
Fission yeast cytoskeletons and cell polarity factors: connecting at the cortexQ36624081
The profile of profilinsQ36903642
A mutant of Arp2p causes partial disassembly of the Arp2/3 complex and loss of cortical actin function in fission yeastQ36954505
Caenorhabditis elegans expresses three functional profilins in a tissue-specific mannerQ36954788
Mid1p/anillin and the septation initiation network orchestrate contractile ring assembly for cytokinesisQ36995378
Assembly of normal actomyosin rings in the absence of Mid1p and cortical nodes in fission yeastQ37010742
The role of the FH1 domain and profilin in formin-mediated actin-filament elongation and nucleationQ37016416
P4510describes a project that usesImageJQ1659584
P433issue2
P304page(s)283-293
P577publication date2014-11-12
P1433published inMolecular Biology of the CellQ2338259
P1476titleFission yeast profilin is tailored to facilitate actin assembly by the cytokinesis formin Cdc12
P478volume26

Reverse relations

Q64911556Molecular mechanisms of contractile-ring constriction and membrane trafficking in cytokinesis.cites workP2860

Search more.