Prediction model for aneuploidy in early human embryo development revealed by single-cell analysis

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Prediction model for aneuploidy in early human embryo development revealed by single-cell analysis is …
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P819ADS bibcode2015NatCo...6.7601V
P6179Dimensions Publication ID1037406783
P356DOI10.1038/NCOMMS8601
P932PMC publication ID4506544
P698PubMed publication ID26151134
P5875ResearchGate publication ID279851805

P50authorCarlos SimónQ5751790
Renee Reijo PeraQ27670653
Shawn L ChavezQ58788803
Maria Vera-RodriguezQ58849666
P2093author name stringCarmen Rubio
P2860cites workNIH Image to ImageJ: 25 years of image analysisQ23319322
Clinical outcomes following selection of human preimplantation embryos with time-lapse monitoring: a systematic reviewQ26827106
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Non-invasive imaging of human embryos before embryonic genome activation predicts development to the blastocyst stageQ46697212
Expression and functional analyses of circadian genes in mouse oocytes and preimplantation embryos: Cry1 is involved in the meiotic process independently of circadian clock regulationQ47227507
Maternal-effect gene Ces5/Ooep/Moep19/Floped is essential for oocyte cytoplasmic lattice formation and embryonic development at the maternal-zygotic stage transitionQ48695786
Live birth after anonymous donation of twice-cryopreserved embryos that had been stored in liquid nitrogen for a cumulative storage time of approximately 13.5 yearsQ48696957
Expression profiling of DNA repair genes in human oocytes and blastocysts using microarraysQ48718101
Quantitative RT-PCR reveals tuberous sclerosis gene, TSC2, mRNA degradation following cryopreservation in the human preimplantation embryoQ48821998
The human zygote inherits its mitotic potential from the male gameteQ49099108
Wide range of chromosome abnormalities in the embryos of young egg donors.Q50651270
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DNA repair signalling pathway genes are overexpressed in poor-quality pre-implantation human embryos with complex aneuploidy.Q50691755
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Increasing the probability of selecting chromosomally normal embryos by time-lapse morphokinetics analysis.Q50733532
Comparison of gene expression in fresh and frozen-thawed human preimplantation embryos.Q50784003
Association of abnormal morphology and altered gene expression in human preimplantation embryos.Q52042294
Human embryos with unevenly sized blastomeres have lower pregnancy and implantation rates: indications for aneuploidy and multinucleation.Q52141671
In vitro development and implantation rates of fresh and cryopreserved sibling zygotes.Q52207890
The cleavage stage embryo.Q53159552
Chromosome instability is common in human cleavage-stage embryos.Q53398239
Internalization of cellular fragments in a human embryo: time-lapse recordings.Q53664579
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Preimplantation genetic screening reveals a high incidence of aneuploidy and mosaicism in embryos from young women undergoing IVFQ81196488
Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocystQ28280404
Requirement for RNA-binding activity of MSY2 for cytoplasmic localization and retention in mouse oocytesQ28508614
Basonuclin: a novel mammalian maternal-effect geneQ28512107
Expression of Fas and Fas ligand mRNA in rat and human preimplantation embryosQ28567877
Maternal depletion of CTCF reveals multiple functions during oocyte and preimplantation embryo developmentQ28586603
Dynamic blastomere behaviour reflects human embryo ploidy by the four-cell stageQ30531076
Transcriptome profiling of human pre-implantation developmentQ30895783
Zygote arrest 1 (Zar1) is a novel maternal-effect gene critical for the oocyte-to-embryo transitionQ31126531
Genome-wide microarray evidence that 8-cell human blastomeres over-express cell cycle drivers and under-express checkpointsQ33548383
Babelomics: an integrative platform for the analysis of transcriptomics, proteomics and genomic data with advanced functional profilingQ33579781
New tools for embryo selection: comprehensive chromosome screening by array comparative genomic hybridizationQ33616513
Preclinical validation of a microarray method for full molecular karyotyping of blastomeres in a 24-h protocolQ33731973
Functional genomics of 5- to 8-cell stage human embryos by blastomere single-cell cDNA analysisQ33737671
Apoptosis in the human embryoQ33751748
Waves of early transcriptional activation and pluripotency program initiation during human preimplantation developmentQ33818101
Analysis of embryo morphokinetics, multinucleation and cleavage anomalies using continuous time-lapse monitoring in blastocyst transfer cycles.Q33820389
Selection of competent blastocysts for transfer by combining time-lapse monitoring and array CGH testing for patients undergoing preimplantation genetic screening: a prospective study with sibling oocytesQ33830129
Differences in gene expression between mouse and human for dynamically regulated genes in early embryoQ33999242
Comparison of epigenetic mediator expression and function in mouse and human embryonic blastomeresQ34074528
Expression of apoptosis-related genes during human preimplantation embryo development: potential roles for the Harakiri gene product and Caspase-3 in blastomere fragmentationQ34179960
The use of morphokinetics as a predictor of embryo implantationQ34206864
Molecular origin of mitotic aneuploidies in preimplantation embryosQ34286611
Cleavage kinetics analysis of human embryos predicts development to blastocyst and implantationQ34300841
Modelling a risk classification of aneuploidy in human embryos using non-invasive morphokineticsQ34334550
Genetic programs in human and mouse early embryos revealed by single-cell RNA sequencingQ34360246
Defining the genomic signature of totipotency and pluripotency during early human developmentQ34685636
Global gene expression profiling of individual human oocytes and embryos demonstrates heterogeneity in early developmentQ34745404
Maternal BRG1 regulates zygotic genome activation in the mouseQ34863379
Comparing thaw survival, implantation and live birth rates from cryopreserved zygotes, embryos and blastocysts.Q35104492
Absence of MSY2 in mouse oocytes perturbs oocyte growth and maturation, RNA stability, and the transcriptomeQ35174982
Transcription factor profiling in individual hematopoietic progenitors by digital RT-PCRQ35215049
Expression of apoptosis-related genes in human oocytes and embryosQ36269726
DNA repair in mammalian embryosQ36671606
Centrioles in the beginning of human developmentQ37523526
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
limmaQ112236343
P407language of work or nameEnglishQ1860
P304page(s)7601
P577publication date2015-07-07
P1433published inNature CommunicationsQ573880
P1476titlePrediction model for aneuploidy in early human embryo development revealed by single-cell analysis
P478volume6

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Q47814105What we can learn from single-cell analysis in development
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